Antioxidant properties of cabergoline: inhibition of brain auto-oxidation and superoxide anion production of microglial cells in rats.

abstract：:beta-Alanine (beta-ALa) is a structural analog of the putative inhibitory transmitters gamma-aminobutyric acid (GABA) and glycine. beta-ALa itself depresses firing in cultured mouse spinal cord (SC) neurons, by selectively increasing membrane conductance to chloride ions. Patch clamp recordings now reveal that beta-AL...

journal_title：Neuroscience letters

authors： Mathers DA,Grewal A,Wang YH

更新日期：1990-01-01 00:00:00

abstract：:Very recent studies in adult gerbils and rats have shown that exposure to sublethal ischemia can confer neuroprotection from subsequent lethal ischemic episodes. To determine if a similar phenomenon can be elicited during the perinatal period, we have developed a preconditioning regimen that involves exposure to normo...

journal_title：Neuroscience letters

authors： Gidday JM,Fitzgibbons JC,Shah AR,Park TS

更新日期：1994-02-28 00:00:00

abstract：:The present study was designed to test the hypothesis that acute administration of alcohol (ethanol) to primary cultured cerebral vascular smooth muscle cells will cause lipid peroxidation, inhibition of IkappaB phosphorylation, and inhibition of nuclear transcription factor-kappa B (NF-kappaB). Ethanol (10, 25, 100 m...

journal_title：Neuroscience letters

authors： Altura BM,Gebrewold A,Zhang A,Altura BT

更新日期：2002-06-07 00:00:00

abstract：:Studies of amino acid release were carried out using frozen sections from brains of schizophrenics and controls. Synaptosomes were prepared via differential centrifugation in Ficoll allowing the veratridine-induced release of aspartate, glutamate, glycine, and GABA to be measured. The release of glutamate and gamma-am...

journal_title：Neuroscience letters

authors： Sherman AD,Davidson AT,Baruah S,Hegwood TS,Waziri R

更新日期：1991-01-02 00:00:00

abstract：:We performed an experiment in which we challenged postural stability in 12 healthy subjects by providing artificial delayed visual feedback. A monitor at eye-height presented subjects with a visual representation of the location of their center-of-pressure (COP) and they were instructed to position their COP as accura...

journal_title：Neuroscience letters

authors： van den Heuvel MR,Balasubramaniam R,Daffertshofer A,Longtin A,Beek PJ

更新日期：2009-03-06 00:00:00

abstract：:'Clipsin' and other peptide bond hydrolase activities that appear to be integral membrane proteins, including two implicated in the formation of the histological hallmarks of Alzheimer's disease, were assayed in the frontal and parietal cortex from a large (n = 45) series of postmortem human brains. Tissues were extra...

journal_title：Neuroscience letters

authors： Stratmann GC,Webster MT,Francis PT,Procter AW,Bowen DM

更新日期：1992-08-31 00:00:00

abstract：:The interaction of NMDA receptor (NMDAR) activation and other mechanisms regulating neuronal excitability have not been thoroughly described. While excess activation of NMDARs results in excitotoxicity, partial activation of NMDARs by d-cycloserine (DCS) is nootropic, enhancing both acquisition and extinction of memor...

journal_title：Neuroscience letters

authors： Donzis EJ,Thompson LT

更新日期：2014-06-13 00:00:00

abstract：:Antipsychotic agents have typically been viewed as acting through dopaminergic targets, although mounting evidence suggests that drugs such as clozapine may act on glutamatergic systems. In order to explore the effects of clozapine on the NMDA class of glutamate receptors, oocytes expressing the NMDA receptor NR1 subu...

journal_title：Neuroscience letters

authors： Levine JB,Martin G,Wilson A,Treistman SN

更新日期：2003-08-07 00:00:00

abstract：:The MgATP-dependent priming step of exocytosis has been suggested to be regulated negatively by GTP-binding protein G0 in permeabilized adrenal chromaffin cells. We have reported that synaptosomal-associated protein of 25 kDa (SNAP-25) and vesicle-associated membrane protein 2 (VAMP-2) form a complex in chromaffin cel...

journal_title：Neuroscience letters

authors： Misonou H,Ohara-Imaizumi M,Kumakura K

更新日期：1997-09-05 00:00:00

abstract：:1,3-di(2-[5-3H]tolyl)Guanidine ([3H]DTG) was found to bind to a single saturable population of binding sites in human cerebral cortex and NCB20 cells, a second low-affinity site was apparent in guinea pig brain. Displacement studies were performed to determine the pharmacology of the [3H]DTG binding site in these 3 me...

journal_title：Neuroscience letters

authors： Knight AR,Gillard J,Wong EH,Middlemiss DN

更新日期：1991-10-14 00:00:00

abstract：:This study aimed to determine the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) on electroencephalograms (EEGs) of rats. Fifteen Sprague-Dawley rats were subject to 100 pulses of 0.5 Hz rTMS, or sham stimulation. EEGs were recorded before stimulation and within 1 min after rTMS or sham st...

journal_title：Neuroscience letters

authors： Li L,Yin Z,Huo X

更新日期：2007-01-29 00:00:00

abstract：:Following unilateral electrolytic lesioning of the rat entorhinal cortex, we assessed changes in messenger RNA (mRNA) levels for four neuron-associated proteins, GAP-43, SCG10, 68 kDa neurofilament (NF68), and alpha 1-tubulin that encode proteins of importance to synaptic remodelling. The mRNA levels for GAP-43 and SC...

journal_title：Neuroscience letters

authors： Zarow C,Finch CE

更新日期：1995-02-09 00:00:00

abstract：:In recent years, animal behavioral models, particularly those used in pain research, have been increasingly scrutinized and criticized for their role in the poor translation of novel pharmacotherapies for chronic pain. This article addresses the use of animal models of pain from the perspective of industrial drug disc...

journal_title：Neuroscience letters

authors： Whiteside GT,Pomonis JD,Kennedy JD

更新日期：2013-12-17 00:00:00

abstract：:We present results of homozygosity mapping in two siblings affected with early onset Parkinson's disease (EOPD) and mutation screening of ATP13A2 in these and other Iranian EOPD patients. Genome-wide SNP homozygosity analysis revealed linkage to a locus that included ATP13A2, and sequencing of the gene revealed a nove...

journal_title：Neuroscience letters

authors： Malakouti-Nejad M,Shahidi GA,Rohani M,Shojaee SM,Hashemi M,Klotzle B,Fan JB,Elahi E

更新日期：2014-08-08 00:00:00

abstract：:Evidence indicates that sympathetic nerves and substance P (SP) are involved in some physiological and pathophysiological changes and activities in retina. The aim of this study was to investigate whether SP participates in the stress reaction and possible involvement of adrenergic mechanisms in modulation of the chan...

journal_title：Neuroscience letters

authors： Yang JH,Meng XX,Xie LS,Guo Z

更新日期：2008-10-10 00:00:00

abstract：:The neurotransmitter gamma-aminobuteric acid (GABA) is believed to have a controlling action on spinal locomotor networks. In spasticity, spinal locomotor networks are thought to play a role. A well known drug in the treatment of spasticity is the GABA(B) agonist Baclofen. We report an inhibitory effect of Baclofen on...

journal_title：Neuroscience letters

authors： de Louw AJ,de Vente J,Steinbusch HP,Steinbusch HW,Troost J,Vles JS

更新日期：2002-03-15 00:00:00

abstract：:Narcolepsy is characterized, beside other features, by excessive daytime sleepiness and disturbed sleep at night. The pineal hormone melatonin may affect the sleep characteristics. The aim of the study was to compare the circadian rhythm in salivary melatonin in narcoleptic patients with that in control healthy subjec...

journal_title：Neuroscience letters

authors： Blazejova K,Illnerova H,Hajek I,Nevsimalova S

更新日期：2008-05-30 00:00:00

abstract：:The objective of this study was to investigate whether berberine in Coptidis Rhizoma extract could be transported in primary cultured cerebral neurons and to study the uptake and transport behavior of berberine through the neurons. The present results showed that the uptake of berberine by the neurons increased linear...

journal_title：Neuroscience letters

authors： Wang X,Xing D,Wang W,Lei F,Su H,Du L

更新日期：2005-05-06 00:00:00

abstract：:Parkin gene mutations are by far the most common mutations in both familial Parkinson's disease (PD) and sporadic PD. Approximately, 50% of parkin mutations is exon dosage mutations (i.e., deletions and duplications of entire exons). Here, we first established a MLPA assay for quick detection of parkin exon rearrangem...

journal_title：Neuroscience letters

authors： Guo JF,Dong XL,Xu Q,Li N,Yan XX,Xia K,Tang BS

更新日期：2015-09-14 00:00:00

abstract：:Alternate serial 1 micron Durcupan resin sections of tiger salamander retina were stained with antisera against GABA and glycine using postembed immunocytochemical techniques. Although the vast majority of neurons were labeled by either GABA or glycine antiserum, a small percentage of presumed amacrine cells in the in...

journal_title：Neuroscience letters

authors： Yazulla S,Yang CY

更新日期：1988-12-19 00:00:00

abstract：:MicroRNAs (miRs) are endogenous small RNAs that regulate gene expression at the post-transcriptional level by mediating mRNA degradation or transcriptional inhibition. MiRs were implicated in the pathogenesis of numerous neurodegenerative diseases, including Parkinson's disease (PD). In this study we analyzed the poss...

journal_title：Neuroscience letters

authors： Lungu G,Stoica G,Ambrus A

更新日期：2013-10-11 00:00:00

abstract：:The relation between phantom limb pain (PLP) and the movement representation of a phantom limb remains controversial in several areas of neurorehabilitation, although there are a few studies in which the representation of phantom limb movement was precisely evaluated. We evaluated the structured movement representatio...

journal_title：Neuroscience letters

authors： Osumi M,Sumitani M,Wake N,Sano Y,Ichinose A,Kumagaya S,Kuniyoshi Y,Morioka S

更新日期：2015-09-25 00:00:00

abstract：:Long-term adrenalectomy results in loss of neurones in the hippocampal formation of the adult rat. The effects of long-term adrenalectomy on spatial learning and exploratory behaviour in adrenalectomized (ADX), adrenalectomized normal weight gain (ADXNW), sham operated and naive control male Sprague-Dawley rats were i...

journal_title：Neuroscience letters

authors： Islam A,Henriksson B,Mohammed A,Winblad B,Adem A

更新日期：1995-07-14 00:00:00

abstract：INTRODUCTION:Quantitative sensory testing (QST) is widely used in human research to investigate the integrity of the sensory function in patients with pain of neuropathic origin, or other causes such as low back pain. Reliability of QST has been evaluated on both sides of the face, hands and feet as well as on the trun...

journal_title：Neuroscience letters

authors： Knutti IA,Suter MR,Opsommer E

更新日期：2014-09-05 00:00:00

abstract：:Post-stroke 'pushing' behaviour appears to be caused by impaired perception of vertical in the roll plane. While pushing behaviour typically resolves with stroke recovery, it is not known if misperception of vertical persists. The purpose of this study was to determine if perception of vertical is impaired amongst str...

journal_title：Neuroscience letters

authors： Mansfield A,Fraser L,Rajachandrakumar R,Danells CJ,Knorr S,Campos J

更新日期：2015-03-17 00:00:00

abstract：:Previous magnetoencephalography (MEG) studies of sleep spindles have identified a complex and widespread distribution in parietal and frontal cortices by fitting a dipolar model to the data. In this study, we used a whole-head 151-channel MEG system with simultaneous electroencephalography (EEG) recording in eight nor...

journal_title：Neuroscience letters

authors： Ishii R,Dziewas R,Chau W,Sörös P,Okamoto H,Gunji A,Pantev C

更新日期：2003-04-03 00:00:00

abstract：:IL-1beta is a proinflammatory cytokine that contributes to psychological stress responses and has been implicated in various psychiatric disorders most notably depression. Preclinical studies also demonstrate that IL-1beta modulates anxiety- and fear-related behaviors, although these findings are difficult to assess b...

journal_title：Neuroscience letters

authors： Koo JW,Duman RS

更新日期：2009-05-29 00:00:00

abstract：:Rabbit retinal Müller cells were isolated by means of papaine and mechanical dissociation. These cells were shown to have a well preserved morphology and to preserve viability for many hours. Intense wheat germ agglutinin binding occurs on the photoreceptor side of Müller cells, especially in the microvillous region. ...

journal_title：Neuroscience letters

authors： Reichenbach A,Dettmer D,Brückner G,Neumann M,Birkenmeyer G

更新日期：1985-03-22 00:00:00

abstract：:A dimeric form of acetylcholinesterase from the electric organ of Torpedo californica was solubilized by phosphatidylinositol-specific phospholipase C from Staphylococcus aureus. The solubilized enzyme had a sedimentation coefficient of 7.3S which was not modified by detergents. The high salt-soluble asymmetric forms ...

journal_title：Neuroscience letters

authors： Futerman AH,Low MG,Silman I

更新日期：1983-09-19 00:00:00

abstract：:In the present experiment, under drinking of 0.01% methamphetamine (MA), young rats exhibited free-running locomotor rhythm ranging from 24.6 to 30.9 h period under light-dark cycle. In contrast, 24-month-old rats showed a low activity and did not exhibit MA-induced free-running rhythm. When MA was injected at a fixed...

journal_title：Neuroscience letters

authors： Shibata S,Minamoto Y,Ono M,Watanabe S

更新日期：1994-05-19 00:00:00