Acute myocardial ischemia up-regulates substance P in the retina of rats.

abstract：:A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes. Complement activation is one of the cardinal pathological features of the inflammation. Intensive AD association studies investigating polymorphisms in inflammatory-related genes have been recently perfor...

journal_title：Neuroscience letters

authors： Rosenmann H,Meiner Z,Kahana E,Aladjem Z,Friedman G,Ben-Yehuda A,Grenader T,Wertman E,Abramsky O

更新日期：2003-01-16 00:00:00

abstract：:Whole-cell recordings were obtained from respiratory neurons by applying patch-clamp techniques in the en bloc medulla of in vitro neonatal rat brainstem-spinal cord preparations. Stable voltage-clamp recordings of excitatory or inhibitory synaptic drive currents and current-clamp recordings of spike discharge of insp...

journal_title：Neuroscience letters

authors： Smith JC,Ballanyi K,Richter DW

更新日期：1992-01-06 00:00:00

abstract：:This study aimed to investigate the cross-modal association of an "abstract symbol," designed for representation of an odor, with its corresponding odor. First, to explore the associations of abstract symbols with odors, participants were asked to match 8 odors with 19 different abstract symbols (Experiment 1). Next, ...

journal_title：Neuroscience letters

authors： Seo HS,Arshamian A,Schemmer K,Scheer I,Sander T,Ritter G,Hummel T

更新日期：2010-07-12 00:00:00

abstract：:In the course of our survey of natural compounds inhibiting prostaglandin E2 release and/or lipopolysaccharide (LPS)-induced transcriptional stimulation via NF-kappaB, a central regulator of inflammatory genes, from natural resources, we found garcinone B, a xanthone from callus tissue culture of Hypericum patulum, as...

journal_title：Neuroscience letters

authors： Yamakuni T,Aoki K,Nakatani K,Kondo N,Oku H,Ishiguro K,Ohizumi Y

更新日期：2006-02-20 00:00:00

abstract：:The morphology of single saccular afferents was studied by the intracellular horseradish peroxidase (HRP) method. Four neurons were sufficiently stained to allow reconstruction of their axonal arborizations. The main axon of these neurons bifurcated into an ascending and a descending branch at the level of the lateral...

journal_title：Neuroscience letters

authors： Imagawa M,Graf W,Sato H,Suwa H,Isu N,Izumi R,Uchino Y

更新日期：1998-01-16 00:00:00

abstract：:The phosphatidylinositol (PI) and phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolytic activities of phosphoinositide-specific phospholipase C (PLC) were measured in membrane and cytosol fractions from 7 discrete areas of the rat brain. Both the PI-PLC and PIP2-PLC specific activities were found to differ significa...

journal_title：Neuroscience letters

authors： Nishida A,Kaiya H,Tohmatsu T,Banno Y,Wakabayashi S,Nozawa Y

更新日期：1988-08-01 00:00:00

abstract：:To elucidate the metabolic process generating amyloid-beta protein (A beta) from beta-amyloid precursor protein (APP) in human brain, we partially purified secretory forms and carboxyl-terminal fragments (CTFs) of APP from the white matter of a Down's syndrome brain. We obtained secretory forms of APP which lack the e...

journal_title：Neuroscience letters

authors： Tokuda T,Tanaka K,Kametani F,Ikeda S,Yanagisawa N

更新日期：1995-02-17 00:00:00

abstract：BACKGROUND/AIM:Depressive disorders are multifactorial diseases, in which cognitive impairment is one of the characteristic feature. One of the molecules that regulate of various cognitive, emotional and behavioural processes is nitric oxide (NO), synthesized from l-arginine by a family of isoformic enzymes known as ni...

journal_title：Neuroscience letters

authors： Talarowska M,Gałecki P,Maes M,Orzechowska A,Chamielec M,Bartosz G,Kowalczyk E

更新日期：2012-02-29 00:00:00

abstract：:Changes in adenosine 3',5'-cyclic monophosphate (cAMP) concentration were measured in cortical synaptosomes. Preincubation with adenosine deaminase reduced cAMP concentration by 45%. Oxotremorine, clonidine, gamma-aminobutyric acid (GABA) and baclofen produced no change in basal concentration. 2-Chloroadenosine and no...

journal_title：Neuroscience letters

authors： Fillenz M,Bloomfield MR

更新日期：1986-02-28 00:00:00

abstract：:Parkinson's disease (PD) is characterized by a loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Adenosine is a neuromodulator that inhibit the release of dopamine via a disinhibitory mechanism. In this study, we investigated the neuroprotective effect of 8-cyclopentyl-1,3-dipropylxanthine and...

journal_title：Neuroscience letters

authors： Fathalla AM,Soliman AM,Moustafa AA

更新日期：2017-03-16 00:00:00

abstract：:The present investigation describes for the first time leg lateral abduction performance during long-term microgravity exposure. Two astronauts took part in the experiments, starting 2 weeks into the mission and lasting for 5 months. Results on joint angles kinematics confirm previous investigations on parabolic fligh...

journal_title：Neuroscience letters

authors： Pedrocchi A,Baroni G,Mouchnino L,Ferrigno G,Pedotti A,Massion J

更新日期：2002-02-22 00:00:00

abstract：:In order to describe how high altitude affects the body during a one night stay at 4000m experiments were performed in a hypobaric chamber and compared to a study on Dachstein (mountain in Austria, 2700m). Ten subjects had to perform a reaction time task at different altitudes. The EEG and ECG were recorded simultaneo...

journal_title：Neuroscience letters

authors： Guger C,Krausert S,Domej W,Edlinger G,Tannheimer M

更新日期：2008-09-12 00:00:00

abstract：:Depression is one of the most prevalent challenges of mental conditions. Yet its exact etiology has not been clear. Chronic stress increases the production of cytokines, which can lead to depression. Hepcidin, an iron modulator, is involved in the inflammation process as well as iron homeostasis. This study was design...

journal_title：Neuroscience letters

authors： Farajdokht F,Soleimani M,Mehrpouya S,Barati M,Nahavandi A

更新日期：2015-02-19 00:00:00

abstract：:Pannexins form single membrane channels that regulate the passage of ions, small molecules and metabolites between the intra- and extracellular compartments. In the central nervous system, these channels are integrated into numerous signaling cascades that shape brain physiology and pathology. Post-translational modif...

journal_title：Neuroscience letters

authors： Lohman AW,Weilinger NL,Santos SM,Bialecki J,Werner AC,Anderson CL,Thompson RJ

更新日期：2019-03-16 00:00:00

abstract：:DJ-1, the causative gene of a familial form of Parkinson's disease (PD), has been reported undergo oxidation preferentially at the 106th cysteine residue (Cys-106) under oxidative stress. Recently, it has been found that the levels of oxidized DJ-1 in erythrocytes of unmedicated PD patients are markedly higher than th...

journal_title：Neuroscience letters

authors： Akazawa YO,Saito Y,Hamakubo T,Masuo Y,Yoshida Y,Nishio K,Shichiri M,Miyasaka T,Iwanari H,Mochizuki Y,Kodama T,Noguchi N,Niki E

更新日期：2010-10-15 00:00:00

abstract：:Peripheral inflammation induced by intraperitoneal (i.p.) injection of Lipopolysaccharide (LPS) is known to cause functional impairments in the brain affecting memory and learning. One of mechanisms may be the interference with neurotrophin (NT) expression and function. In the current study we administered a single, h...

journal_title：Neuroscience letters

authors： Schnydrig S,Korner L,Landweer S,Ernst B,Walker G,Otten U,Kunz D

更新日期：2007-12-11 00:00:00

abstract：:Using antibodies to somatostatin in combination with the avidin-biotin immunohistochemical method, the laminar distribution and morphology of somatostatin-like (SOM-L) immunoreactive cells have been studied in the hippocampal formation of the rat. SOM-L positive cells are present throughout the longitudinal axis of th...

journal_title：Neuroscience letters

authors： Köhler C,Chan-Palay V

更新日期：1982-12-31 00:00:00

abstract：:Lesch-Nyhan syndrome (LNS), caused by the complete deficiency of hypoxanthine phosphoribosyltransferase (HPRT), is characterized by a neurological deficit, the etiology of which is still unclear. Evidence has accumulated indicating that it reflects dopamine deficiency associated with defective arborization of dopamine...

journal_title：Neuroscience letters

authors： Boer P,Brosh S,Wasserman L,Hammel I,Zoref-Shani E,Sperling O

更新日期：2001-04-27 00:00:00

abstract：:Parkinson's disease (PD) is defined as a chronic neurodegenerative disorder which is diagnosed mostly by its clinical manifestations. Reactive oxygen species (ROS) are considered as key modulators in the development of PD. Despite the intensive investigations, antioxidant-dependent molecular mechanisms of initiation a...

journal_title：Neuroscience letters

authors： Hemmati-Dinarvand M,Saedi S,Valilo M,Kalantary-Charvadeh A,Alizadeh Sani M,Kargar R,Safari H,Samadi N

更新日期：2019-09-14 00:00:00

abstract：:Temporal separation and juxtaposition of stimulations for the induction of associative short-term potentiation in the rat hippocampus were examined. A series of stimulations of stratum radiatum during brief tetanic stimulations of stratum oriens resulted in a short-term potentiation (of about 3 min duration) of stratu...

journal_title：Neuroscience letters

authors： Auyeung A,May PB,Goh JW,Sastry BR

更新日期：1987-08-18 00:00:00

abstract：:Fluoride-resistant acid phosphatase (FRAP) has been suggested as an enzymatic marker for nociceptive primary afferent terminals in the spinal dorsal horn, however there has not been demonstrated a direct functional relation between FRAP activity and an increased nociceptive transmission. For this purpose, we quantitat...

journal_title：Neuroscience letters

authors： Glykys J,Guadama M,Marcano L,Ochoa E,Eblen-Zajjur A

更新日期：2003-02-13 00:00:00

abstract：:Rim is a multi-domain, active zone protein that regulates exocytosis and is implicated in vesicle priming and presynaptic plasticity. We recently demonstrated that synaptic defects associated with loss of Caenorhabditis elegans Rim (termed UNC-10) are accompanied by a reduction in docked vesicles adjacent to the presy...

journal_title：Neuroscience letters

authors： Gracheva EO,Hadwiger G,Nonet ML,Richmond JE

更新日期：2008-10-24 00:00:00

abstract：:Increased expression of tumor necrosis factor alpha (TNFalpha) has been shown in adult stroke models. However, its expression and relationship with neuronal apoptosis in neonatal rats with transient middle cerebral artery occlusion (MCAO) have not been clearly elucidated. We studied the expression and distribution of ...

journal_title：Neuroscience letters

authors： Mao M,Hua Y,Jiang X,Li L,Zhang L,Mu D

更新日期：2006-08-07 00:00:00

abstract：:Astrocytes in the CNS produce inflammatory mediators in response to several stimuli and cytokines. Here we investigated the in vitro effect of leptin on inducible nitric oxide synthase (iNOS) expression in a glioma cell line (C6). After hormone stimulation, culture media were analysed for accumulated stable oxidation ...

journal_title：Neuroscience letters

authors： Mattace Raso G,Esposito E,Iacono A,Pacilio M,Coppola A,Bianco G,Diano S,Di Carlo R,Meli R

更新日期：2006-03-27 00:00:00

abstract：:Injections of a wheat germ agglutinin-horseradish peroxidase conjugate were placed in representative areas of the cerebellar cortex of adult tree shrews. Retrogradely labeled cells were found in the medial terminal nucleus (MTN) of the accessory optic system (AOS) when ventral portions of the uvula were involved in th...

journal_title：Neuroscience letters

authors： Haines DE,Sowa TE

更新日期：1985-04-09 00:00:00

abstract：:In spite of systematic investigations, the existence of a specific cortex that could encode for the intensities of somatosensory stimuli, including within nociceptive ranges, is still a matter of debate. The present consensus is that pain is expressed in a distributed network made of thalamus, SII, insula, ACC, and, l...

journal_title：Neuroscience letters

authors： Peyron R,Fauchon C

更新日期：2019-05-29 00:00:00

abstract：:Recent research has shown that pseudowords created by transposing letters are very effective for activating the lexical representation of their base words (e.g., relovution activates REVOLUTION). Furthermore, pseudoword transpositions of consonants are more similar to their corresponding base words than the transposit...

journal_title：Neuroscience letters

authors： Carreiras M,Vergara M,Perea M

更新日期：2007-06-04 00:00:00

abstract：:Mutations in the hairless (hr) gene of mice result in hair follicle and other epithelial defects. The hr gene is expressed at high levels in the brain where it probably participates in the survival and maintenance of some neuronal populations, but whether it also supports glial populations of the central nervous syste...

journal_title：Neuroscience letters

authors： San Jose I,García-Atares N,Pelaez B,Cabo R,Esteban I,Vega JA,Represa J

更新日期：2001-08-24 00:00:00

abstract：:Mental simulation of movements has been widely used to infer about representational aspects of action. On a daily basis, motor planning and execution depends crucially both upon vision and kinesthesia. What if the former is lost? In this study we investigate the physiological changes induced during a mental simulation...

journal_title：Neuroscience letters

authors： Imbiriba LA,Rodrigues EC,Magalhães J,Vargas CD

更新日期：2006-05-29 00:00:00

abstract：:Lowering extracellular calcium concentration [Ca2+]o in rat hippocampal slices can lead to an induction of epileptiform activity. It has been shown that this effect is more pronounced in slices of neonatal rats (postnatal day, PND 8-19) than in mature slices (> PND 40) and it has been suggested that unique N-methyl-D-...

journal_title：Neuroscience letters

authors： Gorter JA,Brady RJ

更新日期：1995-07-21 00:00:00