Modulation of N-methyl-D-aspartic acid receptors by extracellular calcium in immature and adult hippocampal slices: whole cell recordings in CA3 pyramidal cells.

abstract：:Tyrosine hydroxylase-like immunoreactive (TH-IR) neurons with morphological features of interneurons were found throughout the human cerebral cortex. Quantitative estimates in 14 different cytoarchitectonic areas revealed a specific regional distribution pattern, neurons being less dense in primary cortical areas and ...

journal_title：Neuroscience letters

authors： Gaspar P,Berger B,Febvret A,Vigny A,Krieger-Poulet M,Borri-Voltattorni C

更新日期：1987-10-05 00:00:00

abstract：:The activity of single units in the striatum of urethane-anesthetized rats was recorded before and after the systemic administration of 7-nitro-indazole (7-NI; 50 mg/kg intraperitoneally), a selective inhibitor of neuronal nitric oxide (NO) synthase. Two neuronal types were clearly distinguishable electrophysiological...

journal_title：Neuroscience letters

authors： Sardo P,Ferraro G,Di Giovanni G,Galati S,La Grutta V

更新日期：2002-06-14 00:00:00

abstract：:The N-Methyl-D-Aspartate Receptors (NMDARs) are heteromeric cation channels involved in learning, memory, and synaptic plasticity, and their dysregulation leads to various neurodegenerative disorders. Recent evidence has shown that apart from the GluN1/GluN2A and GluN1/GluN2B diheteromeric ion channels, the NMDAR also...

journal_title：Neuroscience letters

authors： Cheriyan J,Balsara RD,Hansen KB,Castellino FJ

更新日期：2016-03-23 00:00:00

abstract：:The present experiment investigated cortical responses of native Italian subjects during reading of short sentences including semantic or morphosyntactic violations. Given the specificity of the Italian language in which the sequencing of words is relatively more free than in English or other languages, we investigate...

journal_title：Neuroscience letters

authors： Angrilli A,Penolazzi B,Vespignani F,De Vincenzi M,Job R,Ciccarelli L,Palomba D,Stegagno L

更新日期：2002-03-29 00:00:00

abstract：:Thyrotropin releasing hormone (TRH) was applied iontophoretically to single neruones in the rat bulbar reticular formation. TRH excited 41 to 56 cells tested; none were inhibited. Excitation developed slowly and was prolonged, and desensitization often occurred. TRH effects were not correlated with effects of acetylch...

journal_title：Neuroscience letters

authors： Briggs I

更新日期：1979-11-01 00:00:00

abstract：:Adaptation of the response to voluntary rapid arm flexion during 3 phases of the step cycle in humans are examined. The onset of arm movement was similar to the standing condition and was unaffected by the phase of the step cycle. The locomotor cycle in contrast was altered. These changes improved the stability of the...

journal_title：Neuroscience letters

authors： Patla AE

更新日期：1986-08-04 00:00:00

abstract：:Astrocytic glial cells from neonatal rat brains were grown in primary culture. Dipeptidyl peptidase II (DPP-II) enzyme activity was measured in cells disrupted by nonionic detergent. The rate of enzyme activity was measured in the presence of various ions, under isosmotic conditions adjusted using mannitol and NaCl. D...

journal_title：Neuroscience letters

authors： Stevens BR,Fernandez A,Sumners C,Hearing L

更新日期：1988-07-08 00:00:00

abstract：:By studying the binding of [3H]glycine and [3H]glutamate to rat synaptic membranes in the presence of 2-amino-5-phosphonovalerate (APV) and kynurenate (KYN) we have demonstrated that KYN is more potent than APV in displacing [3H]glycine, while an opposite order of potency was seen in displacing [3H]glutamate. Moreover...

journal_title：Neuroscience letters

authors： Danysz W,Fadda E,Wroblewski JT,Costa E

更新日期：1989-01-30 00:00:00

abstract：:In the present study, we examined the localizations of canonical transient receptor potential channels (TRPCs) in rat basal ganglia. The dot-like staining pattern of TRPC5 was observed through the globus pallidus (GP) and caudate-putamen. TRPC7 had a strikingly high level of expression in the neuropil in the GP. In th...

journal_title：Neuroscience letters

authors： Chung YH,Kim D,Moon NJ,Oh CS,Lee E,Shin DH,Kim SS,Lee WB,Lee JY,Cha CI

更新日期：2007-07-05 00:00:00

abstract：:Somatosensory amplification refers to the tendency to experience benign and ambiguous somatic sensation as intense, noxious, and disturbing. The construct is helpful in assessing the perceptual style of a variety of somatizing conditions, but there is no human study clarifying the effects of neurological function on s...

journal_title：Neuroscience letters

authors： Nakao M,Barsky AJ,Nishikitani M,Yano E,Murata K

更新日期：2007-03-26 00:00:00

abstract：:Expiratory only resistive loaded breathing (RL) reduces high energy electromyogram (EMG) power (EH) during an isometric contraction of a leg extensor muscle, but not an arm flexor. An interaction between afferent activity during expiratory RL and inspiratory non-loaded phases of breathing, which the contraction spanne...

journal_title：Neuroscience letters

authors： Turner D,Sumners P,Jackson S

更新日期：2000-12-15 00:00:00

abstract：:We studied anxiety-like behavior in the elevated plus-maze (EPM) tests in male Lewis rats on days 2 and 4 of adjuvant arthritis (AA). In plasma we analyzed C-reactive protein (CRP), albumin, ACTH, corticosterone, in the hippocampus the mRNA expression of interleukin-1β (IL-1β), interleukin-6 (IL-6), corticotrophin rel...

journal_title：Neuroscience letters

authors： Skurlova M,Stofkova A,Jurcovicova J

更新日期：2011-01-07 00:00:00

abstract：:Alpha-2 macroglobulin (A2M) is a component of Lewy bodies, a hallmark of Parkinson's disease (PD). In 159 PD patients and 190 normal controls, we studied two A2M polymorphisms by the polymerase chain reaction-restriction fragment length polymorphism method: a five-nucleotide deletion at the 5' splice site of exon 18; ...

journal_title：Neuroscience letters

authors： Nicoletti G,Annesi G,Tomaino C,Spadafora P,Pasqua AA,Annesi F,Serra P,Caracciolo M,Messina D,Zappia M,Quattrone A

更新日期：2002-08-02 00:00:00

abstract：:Leucine-enkephalin-like immunoreactive (ENK-LI) afferent fibers to the feline homologue of the Onuf's nucleus (pudendal motoneurons) originate mainly from lamina X of the sacral cord. They make synaptic contacts chiefly upon dendrites of pudendal motoneurons; the synaptic terminals most often contain pleomorphic synap...

journal_title：Neuroscience letters

authors： Konishi A,Itoh K,Sugimoto T,Yasui Y,Kaneko T,Takada M,Mizuno N

更新日期：1985-10-24 00:00:00

abstract：:Sorbitol accumulation and transmembrane efflux in JS1 schwannoma cells were examined during osmotic stress in the presence of a sorbitol dehydrogenase (SD) inhibitor and following return to iso-osmotic conditions. SD inhibition promoted sorbitol accumulation under hyperglycemic and/or hyperosmotic conditions, and sorb...

journal_title：Neuroscience letters

authors： Mizisin AP,Li L,Calcutt NA

更新日期：1997-06-20 00:00:00

abstract：:Recent evidence has been presented demonstrating that group III mechanoreceptors comprise an important part of the sensory arm of the exercise pressor reflex, which in turn functions to increase arterial blood flow to contracting skeletal muscles. Although group III afferents are stimulated by mechanical distortion of...

journal_title：Neuroscience letters

authors： Leal AK,Stone AJ,Yamauchi K,McCord JL,Kaufman MP

更新日期：2013-10-25 00:00:00

abstract：:Findings from preclinical and clinical research support the involvement of central noradrenergic dysregulation in the etiology of attention deficit hyperactivity disorder (ADHD). Previous studies have suggested that the alpha-2C-adrenergic receptor gene (ADRA2C) is associated with ADHD. The aims of this study were to ...

journal_title：Neuroscience letters

authors： Cho SC,Kim JW,Kim BN,Hwang JW,Shin MS,Park M,Kim SA,Cho DY,Yoo HJ,Chung US,Son JW,Park TW

更新日期：2008-12-03 00:00:00

abstract：:Long-term potentiation (LTP) in the dentate gyrus was previously shown to be enhanced by nicotine, an effect dependent on both homomeric α7 and heteromeric α2β2 nicotinic acetylcholine receptors (nAChR). In our experiments, bath-applied nicotine produced no significant enhancement of LTP. The α7 nAChR silent agonist N...

journal_title：Neuroscience letters

authors： Papke RL,Peng C,Kumar A,Stokes C

更新日期：2018-06-11 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) and insulin promote the survival of 6-7 day old post-natal rat cerebellar granule cells. Previous studies using the PI3 kinase inhibitor, wortmannin and the over-expression of protein kinase B (PKB) have indicated that both PI3 kinase and PKB activation are central for insulin-...

journal_title：Neuroscience letters

authors： Foulstone EJ,Tavaré JM,Gunn-Moore FJ

更新日期：1999-04-02 00:00:00

abstract：:Tacrine (1,2,3,4-tetrahydro-9-acridinamine) inhibited binding of [3H]flunitrazepam to benzodiazepine receptors of guinea pig hippocampus with an inhibition constant of 46 microM at 2 degrees C and 37 degrees C. gamma-Aminobutyric acid (GABA) decreased the affinity of tacrine for the receptor, suggesting that tacrine m...

journal_title：Neuroscience letters

authors： Dawson RM,Poretski M

更新日期：1991-08-19 00:00:00

abstract：:Synaptotagmin I (Syt I), a possible Ca(2+) sensor for neurotransmitter release, was suggested to be involved in neurite outgrowth of chick dorsal root ganglion (DRG) neurons, based on introduction of the antibody against the C2A domain into cells via mechanical lesions. Recently, however, the functional block antibody...

journal_title：Neuroscience letters

authors： Fukuda M,Mikoshiba K

更新日期：2000-12-01 00:00:00

abstract：:Hrk, a regulator of cell death, belongs to the family of pro-apoptotic BH3-only proteins and is known to induce apoptosis in nerve tissue. We examined Hrk gene expression to clarify the role of BH3-only proteins in apoptosis of retinal ganglion cells (RGCs) after optic nerve transection in the adult rat. Reverse trans...

journal_title：Neuroscience letters

authors： Wakabayashi T,Kosaka J,Hommura S

更新日期：2002-01-25 00:00:00

abstract：:Nerve growth factor (NGF) was injected in the brain of neonatal rats. In eleven of thirty-one rats that received 1 microgram of mouse NGF (2.5S form) on postnatal day 3, NGF receptor-like immunoreactivity was found in the preoptic area (POA) and hypothalamus until 12 days after birth. However, no immunoreactivity was ...

journal_title：Neuroscience letters

authors： Nishizuka M,Arai Y

更新日期：1992-04-27 00:00:00

abstract：:An increase in the number of cells undergoing apoptosis was observed in the cingulate sulcus of newborn piglets 48 h after a global hypoxic-ischaemic insult. Apoptotic death was identified morphologically (by light and electron microscopy) and by DNA fragmentation, detected by in situ end labelling. The number of apop...

journal_title：Neuroscience letters

authors： Mehmet H,Yue X,Squier MV,Lorek A,Cady E,Penrice J,Sarraf C,Wylezinska M,Kirkbride V,Cooper C

更新日期：1994-11-07 00:00:00

abstract：:To identify choline acetyltransferase (ChAT) transcript(s) in human foetal brain we used the reverse polymerase chain reaction including different couples of oligonucleotide primers. The analysis indicated the presence of a new choline acetyltransferase transcript containing at its 5' end an untranslated exon (E1A) of...

journal_title：Neuroscience letters

authors： Schmitt M,Garnier JM,Simoni P,Quirin-Stricker C

更新日期：1994-09-12 00:00:00

abstract：:The organotypic hippocampal slice culture technique was used to study how the effects of repeated ethanol withdrawal might differ between males and females at the cellular level, including potential modulation of subsequent insults. A chronic intermittent ethanol (CIE) exposure paradigm was employed, with 3 days of ex...

journal_title：Neuroscience letters

authors： Walls SA,Rosenwasser AM,Devaud LL

更新日期：2013-08-29 00:00:00

abstract：:This study examined the ERP (event-related potential) correlates of categorization processing in brand extension with irrelative task. Participants faced two sequential stimuli in a pair consisting of a soft drink brand name (S1) and a product name (S2) which comprised two categories: beverage (typical product of the ...

journal_title：Neuroscience letters

authors： Wang X,Ma Q,Wang C

更新日期：2012-09-06 00:00:00

abstract：:Day-night variations of gastrin releasing peptide (GRP) in the neuronal somal area of the SCN and the nearby region on the anterior hypothalamic area (AHA) where GRP fibers project, were examined by semiquantitative immunocytochemistry, and compared with those of vasoactive intestinal peptide (VIP). Both in the SCN an...

journal_title：Neuroscience letters

authors： Okamura H,Ibata Y

更新日期：1994-11-07 00:00:00

abstract：:The effects of acute treatment with 1,2,3,4-tetrahydro-9-aminoacridine (THA), a 4-aminopyridine derivative clinically effective in Alzheimer's disease, on beta-adrenoceptor-linked cyclic AMP accumulation have been investigated in cortical and hippocampal structures of young and middle-aged rats. In a first series of e...

journal_title：Neuroscience letters

authors： Dierssen M,Màrmol F,Vivas NM,Clos MV,Gascón S,Badia A

更新日期：1991-10-28 00:00:00

abstract：:The rat spinal cord slice preparation has been used to investigate the sensitivity of deep dorsal horn neurones to the excitatory amino acids N-methyl-D-aspartate (NMDA), quisqualate and L-glutamate. Intracellular recordings were made from 44 neurones in laminae III-VI of 14- to 16-day rats. Superfusion of quisqualate...

journal_title：Neuroscience letters

authors： King AE,Thompson SW,Urban L,Woolf CJ

更新日期：1988-07-08 00:00:00