Current source density distribution of sleep spindles in humans as found by synthetic aperture magnetometry.

abstract：:The cyclic AMP/protein kinase A signaling pathway is thought to be involved in neural differentiation of mesenchymal stem cells. In the present study, we examined the involvement of β-adrenoceptor signaling on the differentiation of mouse induced pluripotent stem (iPS) cells into neural progenitor cells. Mouse iPS cel...

journal_title：Neuroscience letters

authors： Ishizuka T,Goshima H,Ozawa A,Watanabe Y

更新日期：2012-09-06 00:00:00

abstract：:We describe a novel and powerful extracellular method for the staining of a single neuron identified by electrophysiological criteria. This single-unit technique involves the use of glass micro-electrodes (tip diameter: 1.5-2.5 microns) filled with a saline solution (NaCl; 0.5 M) containing 1.5% of biocytin or Neurobi...

journal_title：Neuroscience letters

authors： Pinault D

更新日期：1994-04-11 00:00:00

abstract：:The conversion of α-synuclein from its natively unfolded and α-helical tetrameric forms to an amyloid conformation is central to the emergence of Parkinson's disease. Therefore, prevention of this conversion may offer an effective way of avoiding the onset of this disease or delaying its progress. At different concent...

journal_title：Neuroscience letters

authors： Giffin JC,Richards RC,Craft C,Jahan N,Leggiadro C,Chopin T,Szemerda M,MacKinnon SL,Ewart KV

更新日期：2017-03-22 00:00:00

abstract：:Previous in vitro experiments have indicated that neuronal GABA aminotransferase (GABA-T) differs from extraneuronal GABA-T in sensitivity to certain enzyme inhibitors, including the antiepileptic drug valproate (VPA). In the present experiments, it was studied if GABA-T activity in whole tissue and synaptosomes prepa...

journal_title：Neuroscience letters

authors： Löscher W

更新日期：1993-10-01 00:00:00

abstract：:In the present work, the hypothesis that the ontogenetic development of the corpus callosum (CC) affects the establishment of behavioral lateralization was tested by studying paw preference performance in adult Swiss mice that were subjected to mid-sagittal transection of the CC on the first postnatal day. Magnitude a...

journal_title：Neuroscience letters

authors： Manhães AC,Krahe TE,Caparelli-Dáquer E,Ribeiro-Carvalho A,Schmidt SL,Filgueiras CC

更新日期：2003-09-11 00:00:00

abstract：:In CA3 pyramidal neurons of guinea pig hippocampal slices an outward current activated by the GABAB agonist, baclofen (0.3 microM, Ibac) was reduced by low concentrations of carbachol (Cch, 0.1-0.3 microM). The effect of Cch desensitized suggesting that the receptor subtype involved in this muscarinic effect of Cch wa...

journal_title：Neuroscience letters

authors： Müller W,Brunner H,Misgeld U

更新日期：1989-05-22 00:00:00

abstract：:We assessed whether tolerance develops to the antinociceptive effect of intrathecal (i.t.) orphanin FQ, the endogenous ligand of the orphan opioid-like receptor, and whether there is a cross-tolerance between the antinociceptive effect of i.t. orphanin FQ and the mu opioid receptor agonist morphine. Orphanin FQ admini...

journal_title：Neuroscience letters

authors： Hao JX,Wiesenfeld-Hallin Z,Xu XJ

更新日期：1997-02-14 00:00:00

abstract：:In this study, we investigated two newly reported polymorphisms in association with late onset Alzheimer's disease (AD) in Chinese. They were a -491 A/T polymorphism in the Apolipoprotein E (APOE) promoter region and a five base pair deletion at exon 18 of alpha2-Macroglobin (A2M). There were 196 AD and 180 normal con...

journal_title：Neuroscience letters

authors： Chen L,Baum L,Ng HK,Chan LY,Sastre I,Artíga MJ,Valdivieso F,Bullido MJ,Chiu HF,Pang CP

更新日期：1999-07-16 00:00:00

abstract：:The effect of 5-hydroxytryptamine on the spontaneous activity of neurons of the subthalamic nucleus was examined by recording the extracellular unitary activity in an in vitro slice preparation. The most frequent response to 5-hydroxytryptamine (84% of 57 neurons tested) was an increase (twofold of basal at 10 microM)...

journal_title：Neuroscience letters

authors： Flores G,Rosales MG,Hernández S,Sierra A,Aceves J

更新日期：1995-06-02 00:00:00

abstract：:8-Hydroxy-2-[di-n-propylamino]-tetralin) (8-OH-DPAT), a 5-HT1A/7 receptor agonist, has a chronobiological effect on the circadian system. To identify how the 8-OH-DPAT exerts this effect, we specifically destroyed the serotonergic (5-HT) fibres connecting the median raphe nuclei (RN) to the suprachiasmatic nuclei (SCN...

journal_title：Neuroscience letters

authors： Schuhler S,Saboureau M,Pitrosky B,Pévet P

更新日期：1998-10-30 00:00:00

abstract：:The studies of physiological roles for cellular prion protein (PrP(c)) have focused on possible functions of this protein in the CNS, where it is largely expressed. However, the observation that PrP(c) is expressed also in muscle tissue suggests that the physiological role of PrP(c) might not be limited to the central...

journal_title：Neuroscience letters

authors： Nico PB,Lobão-Soares B,Landemberger MC,Marques W Jr,Tasca CI,de Mello CF,Walz R,Carlotti CG Jr,Brentani RR,Sakamoto AC,Bianchin MM

更新日期：2005-11-04 00:00:00

abstract：:The etiology of schizophrenia is unknown, but the pathogenetic process involves organic changes in brain tissue, which may alter the composition of cerebrospinal fluid (CSF). For the present study, CSF was obtained by lumbar puncture from 22 schizophrenic patients and 38 control patients. We have used scanning electro...

journal_title：Neuroscience letters

authors： Wetterberg L,Nybom R,Bratlid T,Fladby T,Olsson B,Wigzell H

更新日期：2002-08-23 00:00:00

abstract：:The depletion of dopamine in the striatum region and Lewy bodies are the hallmark characteristics of Parkinson's disease. The pathology also includes the upregulation of various Parkinson's disease (PARK) genes and kinases. Two such kinases, LRRK2 and GSK-3β have been directly implicated in the formation of tau and al...

journal_title：Neuroscience letters

authors： Kesh S,Kannan RR,Sivaji K,Balakrishnan A

更新日期：2021-01-01 00:00:00

abstract：:The basal extracellular concentration of dopamine in the nucleus accumbens was quantified using the 'no net flux' microdialysis method, in rats undergoing withdrawal from D-amphetamine. Rats were initially pretreated with saline, or an escalating dose amphetamine regimen known to produce a robust withdrawal syndrome, ...

journal_title：Neuroscience letters

authors： Crippens D,Camp DM,Robinson TE

更新日期：1993-12-24 00:00:00

abstract：:This event-related functional Magnetic Resonance Imaging study examined the differential neural activities associated with a Risky-Gains task in 18 healthy individuals of high (n=9) or low (n=9) impulsiveness, according to their scores on the Barratt Impulsiveness Scale (BIS). The neural activities of people belonging...

journal_title：Neuroscience letters

authors： Lee TM,Chan CC,Han SH,Leung AW,Fox PT,Gao JH

更新日期：2008-06-20 00:00:00

abstract：:The possible voltage-dependence of the dopamine transporter (DAT) was investigated using electrophysiological and electrochemical recordings in rat brain slices containing the substantia nigra (SN). Whole-cell patch clamp recordings of DA neurons, revealed that addition of 15 mM KCl rapidly depolarized the membrane po...

journal_title：Neuroscience letters

authors： Hoffman AF,Zahniser NR,Lupica CR,Gerhardt GA

更新日期：1999-01-29 00:00:00

abstract：:A two pulse technique was used to study the decay of mechanical activation in TTX poisoned mouse extensor digitorum longus (EDL) and soleus muscle fibres. A two microelectrode point voltage clamp technique was used with visual endpoint determination of the threshold potential for activation. The excitatory effect of a...

journal_title：Neuroscience letters

authors： Dulhunty AF

更新日期：1979-10-01 00:00:00

abstract：:Enteric glial cells are increasingly acknowledged as important partners of enteric neurons in the control of gastrointestinal function. They share morphological features and expression of antigenic markers with astrocytes of the central nervous system. Recently, aldehyde dehydrogenase 1 family member L1 (Aldh1L1) has ...

journal_title：Neuroscience letters

authors： Boesmans W,Rocha NP,Reis HJ,Holt M,Vanden Berghe P

更新日期：2014-04-30 00:00:00

abstract：:We previously reported that the amyloid-beta protein (Abeta) reduces the synthesis of acetylcholine (ACh) in a mouse septal cell line, SN56, without causing death of the cells. Here, we report that the ACh-reducing effect of either Abeta 1-28 or Abeta 1-42 (100 nM; 48 h) in SN56 cells can be prevented by a co-treatmen...

journal_title：Neuroscience letters

authors： Pedersen WA,Blusztajn JK

更新日期：1997-12-19 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) play critical roles in maintaining the number of oligodendrocytes in white matter. Previously, we have shown that oxidative stress dampens oligodendrocyte regeneration after white matter damage, while a clinically proven radical scavenger, edaravone, supports oligodendrocyte repo...

journal_title：Neuroscience letters

authors： Takase H,Liang AC,Miyamoto N,Hamanaka G,Ohtomo R,Maki T,Pham LD,Lok J,Lo EH,Arai K

更新日期：2018-03-06 00:00:00

abstract：:Neuronal apoptosis is a contributing cause of disability and death in cerebral ischemia. Nuclear factor-κB (NF-κB) may become a potential therapeutic target for hypoxic/ischemic neuron damage because NF-κB is inactivated after hypoxia exposure. Vascular endothelial growth factor (VEGF) has been found to improve neurol...

journal_title：Neuroscience letters

authors： Mo SJ,Hong J,Chen X,Han F,Ni Y,Zheng Y,Liu JQ,Xu L,Li Q,Yang XH,Sun RH,Yin XY

更新日期：2016-01-01 00:00:00

abstract：:Changes in the activity of the autonomic nervous system are good indicators of alterations in physiological phenomena such as the body temperature, blood glucose, blood pressure. Hesperidin, a flavanone known as vitamin P, has been shown to reduce the levels of serum lipids, cholesterol, and blood pressure. However, h...

journal_title：Neuroscience letters

authors： Shen J,Nakamura H,Fujisaki Y,Tanida M,Horii Y,Fuyuki R,Takumi H,Shiraishi K,Kometani T,Nagai K

更新日期：2009-09-11 00:00:00

abstract：:Size-sieved stem cells (SSCs) derived from human bone marrow have the ability to differentiate into bone, fat and cartilage. SSCs can differentiate into active neural cells after exposure to antioxidant agents. The aim of the present study is to understand if SSCs can be stimulated to differentiate into neurons in res...

journal_title：Neuroscience letters

authors： Tzeng SF,Tsai MJ,Hung SC,Cheng H

更新日期：2004-08-26 00:00:00

abstract：:Baclofen reduced the frequency and aborted the bursts of spontaneous paroxysmal discharges in rat neocortical slices maintained in magnesium-free medium. This action was prevented by pretreatment with barium or caesium, which each increased the ictaform burst frequency, amplitude and duration. 4-Amino-pyridine also in...

journal_title：Neuroscience letters

authors： Ong J,Kerr DI,Johnston GA

更新日期：1990-05-04 00:00:00

abstract：:A well-known event-related potential (ERP) component-the recognition potential (RP) is a response to recognizable stimuli, peaking at around 200-250 ms. The aim of the present study is to put to the test the contrasting perceptual and semantic accounts of the RP, with manipulation of word meaning and presentation form...

journal_title：Neuroscience letters

authors： Zhang Y,Liu Q,Zhang Q

更新日期：2009-04-17 00:00:00

abstract：:Electrical stimulation (20-35 Hz, 2-5 V, 1.5 h) of the pelvic nerve in urethane-anesthetized rats increased the expression of c-fos protein-immunoreactivity primarily in neurons in the L6-S1 segments of the spinal cord. The neurons were localized to areas receiving afferent input from the pelvic viscera including the ...

journal_title：Neuroscience letters

authors： Birder LA,Roppolo JR,Iadarola MJ,de Groat WC

更新日期：1991-08-19 00:00:00

abstract：:Our previous study has shown that both electroacupuncture (EA) and vagus nerve stimulation (VNS) can inhibit cortical epileptiform activities induced by pentylenetetrazole (PTZ). The current study compared the effects of EA and VNS on thalamic neuronal responses to PTZ-induced epileptiform activities. Under general an...

journal_title：Neuroscience letters

authors： Zhang JL,Zhang SP,Zhang HQ

更新日期：2008-08-22 00:00:00

abstract：:Bilateral complete transection of the fimbria-fornix causes a significant increase in nerve growth factor (NGF) content both in the septum and hippocampus of the adult rat as measured by a sensitive immunoassay 7 days after lesioning. The finding, that elevation of NGF in septum (250%) was much more pronounced than th...

journal_title：Neuroscience letters

authors： Weskamp G,Gasser UE,Dravid AR,Otten U

更新日期：1986-09-25 00:00:00

abstract：:Prior motor skill learning (original learning; OL) with one hand (original hand; OH) can affect relearning of the same skill (transfer learning; TL) with the opposite hand (transferred hand; TH). This phenomenon is known as intermanual transfer of learning. We explored specialization of brain activation underlying too...

journal_title：Neuroscience letters

authors： Obayashi S,Suhara T,Kawabe K,Okauchi T,Maeda J,Nagai Y,Iriki A

更新日期：2003-03-20 00:00:00

abstract：:The characteristics of long-term potentiation (LTP) in the hippocampus of rats prenatally exposed to ethanol and treated postnatally with nootropic compounds L-pyroglutamyl-D-alanine-amide (L-pGlu-D-AlaNH2, PGA) or piracetam were studied using in vitro slice preparations. LTP was induced in the CA1 region by the ortho...

journal_title：Neuroscience letters

authors： Chepkova AN,Doreulee NV,Trofimov SS,Gudasheva TA,Ostrovskaya RU,Skrebitsky VG

更新日期：1995-03-31 00:00:00