Antiepileptic effect of electroacupuncture vs. vagus nerve stimulation in the rat thalamus.

abstract：:Cyclosporine A (CsA) is the major immunosuppressive drug used for organ and neural transplantation and the therapy of selected autoimmune diseases. We investigated the effect of CsA on the activity of acetylcholinesterase (AChE) in the frontal cortex, hippocampus, septum, and basal ganglia. AChE was determined spectro...

journal_title：Neuroscience letters

authors： Herink J,Krejcová G,Bajgar J,Svoboda Z,Kvĕtina J,Zivnú P,Palicka V

更新日期：2003-03-27 00:00:00

abstract：:The neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal total biopterin were examined both in rats and mice at different time courses. Results indicate that MPTP caused a significant decrease of total biopterin content in the striatum of mice. This effect occurred as soon as 6 h after...

journal_title：Neuroscience letters

authors： Lee EH

更新日期：1988-06-07 00:00:00

abstract：:The mechanism of action of the 'geste antagonistique', or sensory trick, used by patients with dystonic blepharospasm (BSP) to transiently diminish their symptoms is presently unknown. In this paper we examined the effects induced by a sensory trick consisting of finger contact with the face on the electrically induce...

journal_title：Neuroscience letters

authors： Gómez-Wong E,Martí MJ,Cossu G,Fabregat N,Tolosa ES,Valls-Solé J

更新日期：1998-07-24 00:00:00

abstract：:To clarify the possible involvement of protein kinase (PK) C activation in the excitation and sensitization of polymodal receptors (PMRs), the effects of phorbol 12,13-dibutyrate (PDBu) on PMRs were studied in canine testis-spermatic nerve preparations in vitro. Application of PDBu (10(-7), 10(-6), AND 10(-5) M) for 5...

journal_title：Neuroscience letters

authors： Leng S,Mizumura K,Koda H,Kumazawa T

更新日期：1996-03-08 00:00:00

abstract：:Pineal concentrations of 5-methoxytryptamine, 5-methoxytryptophol, 5-methoxyindole acetic acid and melatonin were determined using high performance liquid chromatography following administration of different monoamine oxidase (MAO) inhibitors (clorgyline, pargyline and deprenyl) to golden hamsters. Plasma concentratio...

journal_title：Neuroscience letters

authors： Raynaud F,Pévet P

更新日期：1991-02-25 00:00:00

abstract：:The anatomical relationships between pro-opiomelanocortin-containing axons and serotonin neurons in the nucleus raphe dorsalis (NRD) of the rat were examined at the light microscope level with antibodies against CLIP (corticotropin-like intermediate lobe peptide), alpha-MSH (alpha-melanocyte-stimulating hormone) and s...

journal_title：Neuroscience letters

authors： Zheng Z,Léger L,Cespuglio R,Jouvet M

更新日期：1991-09-02 00:00:00

abstract：:Mutations in the hairless (hr) gene of mice result in hair follicle and other epithelial defects. The hr gene is expressed at high levels in the brain where it probably participates in the survival and maintenance of some neuronal populations, but whether it also supports glial populations of the central nervous syste...

journal_title：Neuroscience letters

authors： San Jose I,García-Atares N,Pelaez B,Cabo R,Esteban I,Vega JA,Represa J

更新日期：2001-08-24 00:00:00

abstract：:Intracellular recordings were performed in a midpontine slice preparation of the rat brain containing the mesencephalic trigeminal nucleus (MTN). In spite of the previous demonstration of an adenosine deaminase-containing plexus terminating on this nucleus, adenosine, adenosine 5'-triphosphate (ATP), alpha,beta-methyl...

journal_title：Neuroscience letters

authors： Regenold JT,Haas HL,Illes P

更新日期：1988-10-17 00:00:00

abstract：:The effect of insulin-induced hypoglycemic stress on the concentrations of immunoreactive beta-endorphin (ir beta-EP) in plasma and cerebrospinal fluid (CSF) was examined in conscious non-pregnant ewes in which the cisterna magna and a jugular vein had been previously catheterized. In control experiments, no significa...

journal_title：Neuroscience letters

authors： Owens PC,Smith R,Green D,Falconer L

更新日期：1984-08-24 00:00:00

abstract：:The major human neurodegenerative diseases are characterised by ubiquitin-positive intraneuronal inclusions, however the precise nature of the ubiquitin modifications in these structures is unclear. Using a monoclonal antibody specific for Lys63-linked polyubiquitin we have performed the first immunohistochemical anal...

journal_title：Neuroscience letters

authors： Paine S,Bedford L,Thorpe JR,Mayer RJ,Cavey JR,Bajaj N,Sheppard PW,Lowe J,Layfield R

更新日期：2009-09-04 00:00:00

abstract：:Several lines of evidence suggest that dopamine exerts a chronic inhibitory action on GABAergic cells in the striatum, and striatal glutamic acid decarboxylase (GAD) mRNA levels are increased after ipsilateral dopaminergic denervation. In the present study we have used GAD immunocytochemistry to assess whether dopamin...

journal_title：Neuroscience letters

authors： Segovia J,Armstrong DM,Benzing WC,Hornby PJ

更新日期：1991-01-28 00:00:00

abstract：:Brain pericytes are involved in neurovascular dysfunction, neurodegeneration and/or neuroinflammation. In the present study, we focused on the proinflammatory properties of brain pericytes to understand their participation in the induction of inflammation at the neurovascular unit (NVU). The NVU comprises different ce...

journal_title：Neuroscience letters

authors： Matsumoto J,Takata F,Machida T,Takahashi H,Soejima Y,Funakoshi M,Futagami K,Yamauchi A,Dohgu S,Kataoka Y

更新日期：2014-08-22 00:00:00

abstract：:There is little information available on the mechanisms underlying the neuroprotective actions of the organoselenium compound ebselen. In this study, we sought to determine the relationship between alterations in the expression of Bcl-2 and Bax proteins and intracellular levels of calcium and the protective effects of...

journal_title：Neuroscience letters

authors： Xu JH,Hu HT,Liu Y,Qian YH,Liu ZH,Tan QR,Zhang ZJ

更新日期：2006-05-22 00:00:00

abstract：:IGF-1 is an important factor for myelin synthesis and hence possesses therapeutic potential in treating demyelinating disease such as multiple sclerosis. However, IGF-1 poorly crosses the blood-brain barrier. In this study, we investigated the effects of the sex steroid progesterone and the glucocorticoid dexamethason...

journal_title：Neuroscience letters

authors： Chesik D,De Keyser J

更新日期：2010-01-14 00:00:00

abstract：:Recently a full genome survey detected an allelic association between Alzheimer's disease (AD) and the D10S1423 marker on chromosome 10p12-14 (40 cM from the telomere). In this study we examined the D10S1423 marker in an ethnically homogeneous German population of 80 AD patients and two groups of controls, 168 healthy...

journal_title：Neuroscience letters

authors： Majores M,Bagli M,Papassotiropoulos A,Schwab SG,Jessen F,Rao ML,Maier W,Heun R

更新日期：2000-08-11 00:00:00

abstract：:Neuraxial analgesia is often provided using a mixture of local anesthetics and opioids. This combination of agents provides better pain relief and is generally associated with fewer side effects than when either drug is given alone. Local anesthetics have been shown to alter signaling of other G protein-coupled recept...

journal_title：Neuroscience letters

authors： Komai H,McDowell TS

更新日期：2007-05-18 00:00:00

abstract：:Amyloid beta-peptide (Abeta) deposition in brain is important in the development of Alzheimer's disease (AD). Neprilysin (NEP) appears to be the major Abeta degrading enzyme in vivo and reduced mRNA levels of NEP correlates with increased plaque density. We hypothesized that alterations in the NEP promoter region may ...

journal_title：Neuroscience letters

authors： Lilius L,Forsell C,Axelman K,Winblad B,Graff C,Tjernberg L

更新日期：2003-02-06 00:00:00

abstract：:We examined the effect of lateral (visceral) and medial (gustatory) parabrachial nucleus (PBN) lesions on the suppression of milk intake induced with cholecystokinin (CCK) in 24 h food-deprived rats. Irrespective of CCK dose, each type of PBN lesion significantly elevated the consumption of milk. Neither medial nor la...

journal_title：Neuroscience letters

authors： Trifunovic R,Reilly S

更新日期：2003-09-11 00:00:00

abstract：:The involvement of glutamate receptors in the central transmission of somatosympathetic reflexes was studied by examining, in anesthetized rats, the effects of MK-801, an N-methyl-D-aspartate (NMDA) receptor antagonist, and CNQX, a non-NMDA receptor antagonist, on two reflex components, the A- and C-reflexes evoked in...

journal_title：Neuroscience letters

authors： Nagata O,Li WM,Sato A

更新日期：1995-12-08 00:00:00

abstract：:Many experimental observations have demonstrated the modulatory role exerted by several neural structures and neurotransmitters on spontaneous and paroxysmal bioelectric activity of the hippocampus. Recently, the control exerted by locus coeruleus (LC) and its noradrenergic (NA) efferent pathway on different experimen...

journal_title：Neuroscience letters

authors： Ferraro G,Sardo P,Sabatino M,Caravaglios G,La Grutta V

更新日期：1994-03-14 00:00:00

abstract：:The intervibrissal fur-evoked activity in the rat somatosensory cortex was investigated using high-resolution optical imaging with a voltage-sensitive dye. The optical imaging revealed that the intervibrissal fur representation forms a U-shaped band around the borders of the posteromedial barrel subfield (PMBSF), and ...

journal_title：Neuroscience letters

authors： Takashima I,Kajiwara R,Iijima T

更新日期：2005-06-24 00:00:00

abstract：:To test the hypothesis that the expression of specific proteins on peripheral terminals of primary afferents can be attenuated by intrathecal administration of antisense oligodeoxynucleotides (ODNs), we administered ODNs antisense to the mu-opioid receptor to male Sprague-Dawley rats via chronically implanted intrathe...

journal_title：Neuroscience letters

authors： Khasar SG,Gold MS,Dastmalchi S,Levine JD

更新日期：1996-10-25 00:00:00

abstract：:The non-invasive imaging technique of diffusion tensor imaging (DTI) has been used to investigate the microstructural properties of white matter (WM). The present study investigated whether individual differences in the WM structure of normal subjects as measured by fractional anisotropy (FA) values correlate with cog...

journal_title：Neuroscience letters

authors： Takahashi M,Iwamoto K,Fukatsu H,Naganawa S,Iidaka T,Ozaki N

更新日期：2010-06-21 00:00:00

abstract：:Iontophoretic application of the 5-HT2 receptor agonist alpha-methyl-5-HT excited 41 neurones in the rostral ventrolateral medulla, including a population of barosensitive cells. At high ejecting currents (greater than 2-3 x threshold) the excitation was replaced by an inhibition. The excitatory responses evoked by lo...

journal_title：Neuroscience letters

authors： Wang WH,Lovick TA

更新日期：1992-07-06 00:00:00

abstract：:The studies of physiological roles for cellular prion protein (PrP(c)) have focused on possible functions of this protein in the CNS, where it is largely expressed. However, the observation that PrP(c) is expressed also in muscle tissue suggests that the physiological role of PrP(c) might not be limited to the central...

journal_title：Neuroscience letters

authors： Nico PB,Lobão-Soares B,Landemberger MC,Marques W Jr,Tasca CI,de Mello CF,Walz R,Carlotti CG Jr,Brentani RR,Sakamoto AC,Bianchin MM

更新日期：2005-11-04 00:00:00

abstract：:Both autoradiographic and horseradish peroxidase tracing techniques were used to characterize a projection from the dorsal lateral geniculate (DLG) nucleus of the thalamus to visual association cortex (extrastriate cortex) in the macaque monkey. The results show that medium to large caliber DLG axons end to discontinu...

journal_title：Neuroscience letters

authors： Yoshida K,Benevento LA

更新日期：1981-03-10 00:00:00

abstract：:Neurons within the hypothalamic paraventricular nuclei (PVN) have been antidromically invaded following electrical stimulation within the pons and medulla of rats. These neurones are dispersed throughout the PVN and are often found near neurones antidromically invaded only from the pituitary salk. In addition, a small...

journal_title：Neuroscience letters

authors： Zerihun L,Harris M

更新日期：1981-05-06 00:00:00

abstract：:The repressor element-1 silencing transcription factor (REST) has emerged as a key controller of neuronal differentiation and has been shown to play a critical role in the expression of the neuronal phenotype; however, much has still to be learned about its role at specific developmental stages and about the functiona...

journal_title：Neuroscience letters

authors： Antoniotti S,Ruffinatti FA,Torriano S,Luganini A,D'Alessandro R,Lovisolo D

更新日期：2016-08-26 00:00:00

abstract：:Calcium homeostasis in synaptosomes is altered during ageing. The cytosolic free calcium concentration, [Ca2+]i was determined in synaptosomes and crude synaptosomal fractions from 3- and 24-month-old rats with the fluorescent indicator quin-2. The [Ca2+]i were around two times higher in 24-month-old rats than in adul...

journal_title：Neuroscience letters

authors： Martinez A,Vitórica J,Satrústegui J

更新日期：1988-06-07 00:00:00

abstract：:We studied axonal branching of 14 parabrachial nucleus neurons, activated antidromically from 2 of the 3 stimulation sites, i.e. the ipsi- and contralateral thalamic taste area (TTAs) and the ipsilateral central nucleus of the amygdala (CA). Making use of antidromic latencies, collision times and refractory periods at...

journal_title：Neuroscience letters

authors： Hayama T,Ogawa H

更新日期：1987-12-16 00:00:00