Distribution of the pro-opiomelanocortin-immunoreactive axons in relation to the serotoninergic neurons in the dorsal raphe nucleus of the rat.

abstract：:We have examined the morphology and distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-diaphorase) cells in the retina of the guinea pig. Two morphologically distinct classes of labelled cells were detected, one with larger, darkly labelled somata commonly located in the inner nuclear layer ...

journal_title：Neuroscience letters

authors： Cobcroft M,Vaccaro T,Mitrofanis J

更新日期：1989-08-14 00:00:00

abstract：:To investigate the working mechanism of the conflict processing system, pairs of colored numbers were sequentially presented on a screen to subjects. They were asked to determine if the magnitude or the color of the two numbers was identical. Event-related potentials (ERPs) were recorded at the same time. A negative p...

journal_title：Neuroscience letters

authors： Wang H,Wang Y,Kong J,Cui L,Tian S

更新日期：2001-02-09 00:00:00

abstract：:Adenosine modulates hippocampal synaptic plasticity, namely long-term potentiation (LTP) and long-term depression (LTD), through activation of A1 and A2A receptors. We now report a novel role for the recently described adenosine A3 receptor in the regulation of synaptic plasticity in the CA1 area of hippocampal slices...

journal_title：Neuroscience letters

authors： Costenla AR,Lopes LV,de Mendonça A,Ribeiro JA

更新日期：2001-04-13 00:00:00

abstract：:Changes in the distribution pattern of mRNA encoding the zif268 transcription factor (also referred to as NGFI-A, Krox-24 or EGR-1) were investigated by in situ hybridization histochemistry during postnatal rat brain development. Marked changes in zif268 expression patterns were seen in particular in the cerebral cort...

journal_title：Neuroscience letters

authors： Herms J,Zurmöhle U,Schlingensiepen R,Brysch W,Schlingensiepen KH

更新日期：1994-01-03 00:00:00

abstract：:Antidepressants such as tricyclic antidepressants, and serotonin noradrenaline reuptake inhibitors are a first-line treatment for neuropathic pain. Here, we aimed to determine the involvement of the spinal dopaminergic system in the antihyperalgesic effects of antidepressants in a rat model of neuropathic pain induced...

journal_title：Neuroscience letters

authors： Chen M,Hoshino H,Saito S,Yang Y,Obata H

更新日期：2017-05-10 00:00:00

abstract：:Previous studies have showed that SIN-1, a nitric oxide (NO) donor, injected into the dorsolateral column of the periaqueductal gray (dlPAG) induces flight reactions. This drug, however, can also produce peroxynitrite, which may interfere in this effect. In addition, it is also unknown if this effect is mediated by lo...

journal_title：Neuroscience letters

authors： Braga AA,Aguiar DC,Guimarães FS

更新日期：2009-08-07 00:00:00

abstract：:The functional role of non-adrenergic non-cholinergic (NANC) nerves in the autonomic control of the male mini-pig bladder neck was investigated in the present study. Electrical stimulation of muscle strips from male mini-pig bladder neck showed biphasic response with initial phasic contraction followed by post-contrac...

journal_title：Neuroscience letters

authors： Tong YC,Hung YC,Cheng JT

更新日期：1997-04-11 00:00:00

abstract：:Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide that has been shown to cause peripheral sensitization of knee joint afferents; however, the effect of the peptide on joint pain behaviour is unknown. In addition to having a direct effect on peripheral nerves, N/OFQ has also been shown to activate connectiv...

journal_title：Neuroscience letters

authors： McDougall JJ,Larson SE

更新日期：2006-05-01 00:00:00

abstract：:Cholecystokinin (CCK) is suggested to be involved, e.g. in the central nervous modulation of food intake, possibly by acting within specific hypothalamic nuclei. Perinatal overnutrition predisposes to permanent obesity and hyperphagia, while underlying mechanisms are unclear. By reducing the litter size from the 3rd t...

journal_title：Neuroscience letters

authors： Plagemann A,Rake A,Harder T,Melchior K,Rohde W,Dörner G

更新日期：1998-12-11 00:00:00

abstract：:We have investigated whether administration of staurosporine, which has been reported to induce differentiation in the human neuroblastoma cell in vitro, attenuates amnesia induced by basal forebrain lesion in rats. Multiple dosage of staurosporine at the doses of 0.05 and 0.1 mg/kg (i.p.) attenuated the impaired perf...

journal_title：Neuroscience letters

authors： Nabeshima T,Ogawa S,Nishimura H,Fuji K,Kameyama T,Sasaki Y

更新日期：1991-01-14 00:00:00

abstract：:Excessive activation of the N-methyl-D-aspartate (NMDA) receptor-channel complex has been implicated as one of the mechanisms by which ischemia-induced neuronal damage is mediated. Elevated glycine levels during ischemia may contribute to damage mediated by the NMDA receptor as glycine binding potentiates NMDA respons...

journal_title：Neuroscience letters

authors： Wood ER,Bussey TJ,Phillips AG

更新日期：1992-09-28 00:00:00

abstract：:This study compared the immediate and prolonged effects of acute bouts of active and passive leg cycling on the soleus H-reflex among 12 young healthy men. The soleus H-reflex was measured immediately before and then 10 and 30 min after 20 min of active, unloaded leg cycling, passively induced leg cycling, and quiet r...

journal_title：Neuroscience letters

authors： Motl RW,Knowles BD,Dishman RK

更新日期：2003-08-21 00:00:00

abstract：:This study aimed to investigate the effects of ghrelin, as a neuroprotective agent, on cognitive impairment and apoptosis pathway in methamphetamine-treated male rats. Sixty adult male Wistar rats were randomly divided into six groups (n = 10): Saline/Saline (SS), Saline/Ghrelin (SG), Methamphetamine/Simultaneous Sali...

journal_title：Neuroscience letters

authors： Fallahi S,Babri S,Farajdokht F,Ghiasi R,Soltani Zangbar H,Karimi P,Mohaddes G

更新日期：2019-08-10 00:00:00

abstract：:Changes in the intracellular Ca2+ concentration ([Ca2+]i) induced by ischemia in vitro (oxygen-glucose deprivation) were continuously recorded using fura-2-loaded hippocampal slices under normal (pH 7.4), acidotic (pH 6.8) and alkalotic (pH 7.8) conditions. Oxygen-glucose deprivation induced an initial slow and a subs...

journal_title：Neuroscience letters

authors： Ebine Y,Fujiwara N,Shimoji K

更新日期：1994-02-28 00:00:00

abstract：:Alterations of 'peripheral-type' benzodiazepine receptors (PTBRs) in brain are a feature of hepatic encephalopathy (HE). Although ammonia toxicity has been implicated in the disorder, recent findings suggest an accumulation of manganese in the brains of cirrhotic patients dying in hepatic coma. In this study, we exami...

journal_title：Neuroscience letters

authors： Hazell AS,Desjardins P,Butterworth RF

更新日期：1999-08-13 00:00:00

abstract：:Preconditioning increases the neurons' resistance to subsequent hypoxia. An in vitro study was conducted to explore kinetic aspects of hypoxic preconditioning. Hippocampal slices were exposed to one single or repeated episodes of oxygen and glucose deprivation (OGD). The interval between OGD episodes varied between 30...

journal_title：Neuroscience letters

authors： Brödemann R,Peters B,Höllt V,Becker A

更新日期：2014-01-13 00:00:00

abstract：:We evaluated effect of aging, gender and eye (sighting) dominance on relationship between visual evoked flow response (VEFR) and visual evoked potential (VEP), which refers to neurovascular coupling. The VEFR was defined as a percentage increase of the ratio of mean blood flow velocity in the contralateral (according ...

journal_title：Neuroscience letters

authors： Topcuoglu MA,Aydin H,Saka E

更新日期：2009-03-06 00:00:00

abstract：:Changes in adenosine 3',5'-cyclic monophosphate (cAMP) concentration were measured in cortical synaptosomes. Preincubation with adenosine deaminase reduced cAMP concentration by 45%. Oxotremorine, clonidine, gamma-aminobutyric acid (GABA) and baclofen produced no change in basal concentration. 2-Chloroadenosine and no...

journal_title：Neuroscience letters

authors： Fillenz M,Bloomfield MR

更新日期：1986-02-28 00:00:00

abstract：:The bradykinin B2 receptor (B2R) mediates many physiological processes such as hypotension, inflammation and blood-vessel permeability. Hypoxia/reoxygenation (H/R) induces neuronal cell apoptosis. It was found that B2R expression was enhanced in primary cultured cortical neurons after H/R treatment. Addition of bradyk...

journal_title：Neuroscience letters

authors： Tang M,Cui M,Dong Q,Ren HM,Xiao BG,Luo BY,Shao Y,Liu L,Zhou HG

更新日期：2009-01-23 00:00:00

abstract：:Cortical depolarizations in the periphery of focal ischemia result in metabolic disturbances which contribute to the progression of the ischemic injury. In this experimental study, therefore, it was examined whether the duration of peri-infarct depolarizations, which reflects the severity of a metabolic mismatch, is d...

journal_title：Neuroscience letters

authors： Mies G

更新日期：1997-01-17 00:00:00

abstract：:The aim of this study was to investigate the relationship between the functional C957T single-nucleotide polymorphism of the dopamine D2 receptor (DRD2) gene and the risk for schizophrenia. We therefore conducted a case-control association study of 188 Finnish schizophrenia patients meeting the DSM-IV criteria and 384...

journal_title：Neuroscience letters

authors： Hänninen K,Katila H,Kampman O,Anttila S,Illi A,Rontu R,Mattila KM,Hietala J,Hurme M,Leinonen E,Lehtimäki T

更新日期：2006-10-30 00:00:00

abstract：:Intracellular regulation of NMDA-receptor-mediated currents in cultured rat spinal dorsal horn neurons was investigated by means of simultaneously recording whole-cell currents and intracellular Ca2+ concentration ([Ca2+]i). During recordings in which EGTA (11 mM) was used to buffer intracellular Ca2+, NMDA currents s...

journal_title：Neuroscience letters

authors： Wang YT,Pak YS,Salter MW

更新日期：1993-07-23 00:00:00

abstract：:Synaptic plasticity in olfactory inputs to the lateral entorhinal cortex may result in lasting changes in the processing of olfactory stimuli. Changes in dopaminergic tone can have strong effects on basal evoked synaptic responses in the superficial layers of the entorhinal cortex, and the current study investigated w...

journal_title：Neuroscience letters

authors： Caruana DA,Reed SJ,Sliz DJ,Chapman CA

更新日期：2007-10-09 00:00:00

abstract：:Peripheral neuropathic pain is a common complication in the diabetic patients, and the underlying central mechanism remains unclear. Forebrain anterior cingulate cortex (ACC) is critically involved in the supraspinal perception of physical and affective components of noxious stimulus and pain modulation. Excitatory gl...

journal_title：Neuroscience letters

authors： Li W,Wang P,Li H

更新日期：2014-05-07 00:00:00

abstract：:Binding of [3H]ethynylbicycloorthobenzoate ([3H]EBOB) to the gamma-aminobutyric acid type A (GABAA) receptor of cultured cerebellar granule neurons is inhibited by GABA, muscimol and 3-aminopropanesulfonic acid with IC50 values of 69-250 nM. Sensitivity to these GABA mimetics is lower by 3-4-fold for cerebellum and 10...

journal_title：Neuroscience letters

authors： Huang J,Casida JE

更新日期：1997-04-04 00:00:00

abstract：:Bone mesenchymal stem cells (BMSCs) are an attractive donor graft source because of the potential of self-renewal and multi-direction differentiation. However, it is a great challenge to induce BMSCs to specifically differentiate to dopamine (DA) neurons for the treatment of Parkinson's disease. Because the striatum i...

journal_title：Neuroscience letters

authors： Yang S,Gao Q,Bao L,Zhang J,Hu Y,Bing L,Sun J,Hao J,Chen C,Li S,Poon WS,Sun J,Gao Y

更新日期：2012-11-21 00:00:00

abstract：:A common obstacle in clinical management of pathological pain is the poor response to opioid analgesics. We now report that delta9-tetrahydrocannabinol (delta9-THC)-induced antinociception remained effective in rats with pathological pain. The selective central cannabinoid receptor antagonist SR141716A, but not the ge...

journal_title：Neuroscience letters

authors： Mao J,Price DD,Lu J,Keniston L,Mayer DJ

更新日期：2000-02-11 00:00:00

abstract：:Although synaptically released, vesicular Zn(2+) has been proposed to play a neuromodulatory or neuronal signaling role at the mossy fiber-CA3 synapse, Zn(2+) release remains controversial, especially when detected using fluorescent imaging. In the present study, we investigated synaptically released Zn(2+) at the mos...

journal_title：Neuroscience letters

authors： Bastian C,Li YV

更新日期：2007-05-29 00:00:00

abstract：:We have investigated the presence of mutations in the parkin gene in patients with early-onset parkinsonism. Direct sequencing of the polymerase chain reaction (PCR) products showed a homozygous G deletion in the exon 7 (c.871delG) in one patient. This was a 38-year-old Moroccan woman with a history of parkinsonism of...

journal_title：Neuroscience letters

authors： Muñoz E,Pastor P,Martí MJ,Oliva R,Tolosa E

更新日期：2000-07-28 00:00:00

abstract：:Intracellular recordings were made from neurons in rabbit vesical pelvic ganglia (VPG), in vitro. Increasing the frequency of preganglionic-nerve stimulations from 0.1-1 Hz to 10-20 Hz facilitated fast excitatory postsynaptic potentials (EPSPs), resulting in a generation of action potentials. Acetylcholine-induced res...

journal_title：Neuroscience letters

authors： Nishimura T,Yoshida M,Nagatsu I,Akasu T

更新日期：1989-08-28 00:00:00