Allelic association between the D10S1423 marker and Alzheimer's disease in a German population.

abstract：:The human craniofacial muscles innervated by the facial nerve typically lack muscle spindles. However these muscles have proprioception that participates in the coordination of facial movements. A functional substitution of facial proprioceptors by cutaneous mechanoreceptors has been proposed but at present this alter...

journal_title：Neuroscience letters

authors： Cobo JL,Abbate F,de Vicente JC,Cobo J,Vega JA

更新日期：2017-02-15 00:00:00

abstract：:The rostral ventromedial medulla (RVM) has been established as part of a descending pain-modulatory pathway. While the RVM has been shown to modulate homosegmental nociceptive reflexes such as tail flick or hindpaw withdrawal, it is not known what role the RVM plays in modulating the magnitude of multisegmental, organ...

journal_title：Neuroscience letters

authors： Jinks SL,Carstens EE,Antognini JF

更新日期：2007-10-22 00:00:00

abstract：:The major human neurodegenerative diseases are characterised by ubiquitin-positive intraneuronal inclusions, however the precise nature of the ubiquitin modifications in these structures is unclear. Using a monoclonal antibody specific for Lys63-linked polyubiquitin we have performed the first immunohistochemical anal...

journal_title：Neuroscience letters

authors： Paine S,Bedford L,Thorpe JR,Mayer RJ,Cavey JR,Bajaj N,Sheppard PW,Lowe J,Layfield R

更新日期：2009-09-04 00:00:00

abstract：:The dopaminergic system has a long history of being associated with reward-related activities but the developmental consequences of blocking dopamine receptor function on reward-based associative learning has been less studied. To this end, male, Long Evans rats were systemically (i.p.) treated with the dopamine recep...

journal_title：Neuroscience letters

authors： Holahan MR,Goheen K

更新日期：2020-04-23 00:00:00

abstract：:Tissue-type plasminogen activator (tPA) plays important roles in the regulation of synaptic plasticity in the hippocampus and cerebellum. We found that the expression of tPA mRNA in the visual cortex was increased significantly by the peripheral administration of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS; 100 mg...

journal_title：Neuroscience letters

authors： Mataga N,Imamura K,Shiomitsu T,Yoshimura Y,Fukamauchi K,Watanabe Y

更新日期：1996-11-08 00:00:00

abstract：:The strict photoperiodic dependence of gonadotropic function observed in mink provides an excellent physiological model for studying the activity of GnRH hypothalamic neurons. In mink, exposure to more than 10 h light inhibits the activity of this neurohormonal system. Melatonin plays an essential role in this type of...

journal_title：Neuroscience letters

authors： Boissin-Agasse L,Barberis C,Audigier S,Roch G,Boissin J

更新日期：1992-09-14 00:00:00

abstract：:A seizure disorder, characterized by sporadic tonic/clonic seizures has been identified in a strain of mice carrying the weaver (wv) gene. Breeding studies and a review of the literature indicate that this is either a property of the wv gene or linked to it tightly. ...

journal_title：Neuroscience letters

authors： Eisenberg B,Messer A

更新日期：1989-01-16 00:00:00

abstract：:Deep brain stimulation (DBS) of the anterior limb of the internal capsule (ALIC) may be effective in treating depression. Parental verbal abuse has been linked to decreased fractional anisotropy (FA) of white matter and reduced FA correlated with depression and anxiety scores. Utilizing a nonhuman primate model of moo...

journal_title：Neuroscience letters

authors： Coplan JD,Abdallah CG,Tang CY,Mathew SJ,Martinez J,Hof PR,Smith EL,Dwork AJ,Perera TD,Pantol G,Carpenter D,Rosenblum LA,Shungu DC,Gelernter J,Kaffman A,Jackowski A,Kaufman J,Gorman JM

更新日期：2010-08-16 00:00:00

abstract：:Membrane currents of cultured human monocytes and rat microglia were recorded with the whole-cell patch clamp technique. Freshly isolated monocytes or resting (proliferating) microglia express only inwardly rectifying K+ channels. However, incubation in teflon bags leads to the expression of additional, outwardly rect...

journal_title：Neuroscience letters

authors： Nörenberg W,Appel K,Bauer J,Gebicke-Haerter PJ,Illes P

更新日期：1993-09-17 00:00:00

abstract：:Cyclins are regulatory proteins of the cell cycle which bind and activate kinases. In gliomas, contrary to many malignancies, cyclin D1 is rarely amplified, but together with other cyclins, it increases with anaplasia. In a series of 23 surgical biopsies of grade II and III oligodendroglioma, cyclin D1, E, A, B1, CDK4...

journal_title：Neuroscience letters

authors： Fiano V,Ghimenti C,Schiffer D

更新日期：2003-08-21 00:00:00

abstract：:Asperger Syndrome (AS) is characterized by normal language development but deficient understanding and use of the intonation and prosody of speech. While individuals with AS report difficulties in auditory perception, there are no studies addressing auditory processing at the sensory level. In this study, event-relate...

journal_title：Neuroscience letters

authors： Jansson-Verkasalo E,Ceponiene R,Kielinen M,Suominen K,Jäntti V,Linna SL,Moilanen I,Näätänen R

更新日期：2003-03-06 00:00:00

abstract：:Cognitive impairment in Parkinson's disease is accompanied by a marked decrease of cerebrocortical nicotinic receptors. To study the putative site of impaired receptor synthesis, frontal cortices of Parkinson patients with cognitive dysfunction have been screened for the expression of the nicotinic receptor alpha 4 su...

journal_title：Neuroscience letters

authors： Schröder H,de Vos RA,Jansen EN,Birtsch C,Wevers A,Lobron C,Nowacki S,Schröder R,Maelicke A

更新日期：1995-03-10 00:00:00

abstract：:Transcriptomic studies of murine D3 embryonic stem (ES) cells deficient in the purinergic biosynthetic function hypoxanthine guanine phosphoribosyltransferase (HPRT) and undergoing dopaminergic neuronal differentiation has demonstrated a marked shift from neuronal to glial gene expression and aberrant expression of mu...

journal_title：Neuroscience letters

authors： Kang TH,Friedmann T

更新日期：2015-03-17 00:00:00

abstract：:The aim of the present study is to show that the sensorimotor system makes a differential use of visual and internal (proprioception and efferent copy) signals when evaluating either the spatial or the dynamical components of our own motor response carried out under a remote visual feedback. Subjects were required to ...

journal_title：Neuroscience letters

authors： Boy F,Palluel-Germain R,Orliaguet JP,Coello Y

更新日期：2005-09-23 00:00:00

abstract：:Secretion of alpha-melanophore-stimulating hormone (alpha-MSH) from the neuroendocrine melanotrope cells in the intermediate lobe of the pituitary gland of the clawed frog Xenopus laevis is regulated by various inhibitory, stimulatory and autocrine factors. The neuropeptide sauvagine stimulates alpha-MSH secretion by ...

journal_title：Neuroscience letters

authors： van den Hurk MJ,Jenks BG,Roubos EW,Scheenen WJ

更新日期：2005-03-29 00:00:00

abstract：:Effect of 1-methyl-4-phenylpyridinium ion (MPP+) on adenosine triphosphate (ATP) synthesis was studied using isolated mitochondrial preparations from mouse brains. Oxidation of glutamate + malate in the mitochondria estimated by polarography was significantly inhibited by MPP+, and synthesis of ATP was inhibited to ap...

journal_title：Neuroscience letters

authors： Mizuno Y,Suzuki K,Sone N,Saitoh T

更新日期：1987-10-16 00:00:00

abstract：:The results of several studies have suggested that local circuit neurons, or interneurons, of area CA1 of hippocampus use gamma-aminobutyric acid (GABA) as their neurotransmitter. However, when these cells were labelled by intracellular dye injection, and examined immunocytochemically with antisera raised against GABA...

journal_title：Neuroscience letters

authors： Scharfman HE,Kunkel DD,Schwartzkroin PA

更新日期：1989-01-02 00:00:00

abstract：:Immunomorphological staining demonstrates that class I major histocompatibility complex (MHC)-coded antigen expression can be selectively induced on otherwise class I-negative rat nerve cells by peripheral axotomy. Induction of class I as well as class II antigen expression was simultaneously seen on non-neural cells ...

journal_title：Neuroscience letters

authors： Maehlen J,Schröder HD,Klareskog L,Olsson T,Kristensson K

更新日期：1988-09-23 00:00:00

abstract：:An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been identified as an important cell surface marker to enrich the stem-like population in va...

journal_title：Neuroscience letters

authors： Dong L,Qi N,Ge RM,Cao CL,Lan F,Shen L

更新日期：2010-11-05 00:00:00

abstract：:This report concerns an ultrastructural study of the synapses present on the surface of somata of normal-looking Betz cells in the fifth layer of motor cortex of seven patients with amyotrophic lateral sclerosis (ALS). Specimens from 12 age-matched, neurologically normal control individuals were included for compariso...

journal_title：Neuroscience letters

authors： Sasaki S,Iwata M

更新日期：1999-06-11 00:00:00

abstract：:Immunohistochemical and biochemical investigations showed that significant protein nitration occurs in human gliomas, especially in grade IV glioblastomas at the level of astrocytes and oligodendrocytes and neurones. Enhanced alpha-tubulin immunoreactivity was co-present in the same elements in the glioblastomas. Prot...

journal_title：Neuroscience letters

authors： Fiore G,Di Cristo C,Monti G,Amoresano A,Columbano L,Pucci P,Cioffi FA,Di Cosmo A,Palumbo A,d'Ischia M

更新日期：2006-02-06 00:00:00

abstract：:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain t...

journal_title：Neuroscience letters

authors： Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

更新日期：2008-08-08 00:00:00

abstract：:Recently, the potent cholinesterase inhibitor (-)-huperzine A (HupA) was demonstrated to protect neuronal and glial cells against the cytotoxicity of beta-amyloid (Abeta). Since the unnatural (+)-HupA is a much less potent inhibitor, it was of interest to examine the stereoselectivity of cellular protection by the two...

journal_title：Neuroscience letters

authors： Zhang HY,Liang YQ,Tang XC,He XC,Bai DL

更新日期：2002-01-14 00:00:00

abstract：:Decreased expression of NT-3 mRNA in the sciatic nerve and leg muscles of streptozotocin (STZ)-diabetic rats has been associated with the pathogenesis of diabetic neuropathy. The aim of this study was to determine whether STZ-induced diabetes also affects the expression of NT-3 mRNA in the central and peripheral proje...

journal_title：Neuroscience letters

authors： Cai F,Tomlinson DR,Fernyhough P

更新日期：1999-03-26 00:00:00

abstract：:The entorhinal cortex (EC) is an essential relay station in neocortical - hippocampal information transfer and memory functions. Layer II stellate and layer III pyramidal neurons show specific damage in Alzheimer's disease and epilepsy, respectively. Using whole cell patch clamp recording in rat brain slices we here d...

journal_title：Neuroscience letters

authors： Visan V,Heinemann U,Volynets A,Müller W

更新日期：2002-07-26 00:00:00

abstract：:Many studies have shown that minocycline, an antibacterial tetracycline, suppresses experimental pain. While minocycline's positive effects on pain resolution suggest that clinical use of such drugs may prove beneficial, minocycline's antibiotic actions and divalent cation (Ca(2+); Mg(2+)) chelating effects detract fr...

journal_title：Neuroscience letters

authors： Bastos LF,Godin AM,Zhang Y,Jarussophon S,Ferreira BC,Machado RR,Maier SF,Konishi Y,de Freitas RP,Fiebich BL,Watkins LR,Coelho MM,Moraes MF

更新日期：2013-05-24 00:00:00

abstract：:In the present study, the effects of fluvoxamine on the inhibition of gastrointestinal transit, antinociception and hyperlocomotion induced by morphine were investigated in mice. Treatment with morphine (10 mg/kg, subcutaneously (s.c.)) inhibited gastrointestinal transit and hyperlocomotion. These effects were attenua...

journal_title：Neuroscience letters

authors： Ise Y,Katayama S,Hirano M,Aoki T,Narita M,Suzuki T

更新日期：2001-02-16 00:00:00

abstract：:Using a new polyclonal antibody against prostacyclin (PGI2)-synthase this enzyme was shown to be present in neuronal cells of bovine, rat and human brain, most abundantly in Purkinje cells of the cerebellum and cortical neurons, but not in glial cells. Western blots confirmed the specificity of the antibody and applie...

journal_title：Neuroscience letters

authors： Mehl M,Bidmon HJ,Hilbig H,Zilles K,Dringen R,Ullrich V

更新日期：1999-08-27 00:00:00

abstract：:This report describes sensory reinnervation of muscle receptors in humans. In this study, sensory function was investigated in fourteen patients with brachial plexus injury, whose musculocutaneous nerve was surgically sutured with intercostal nerves for reconstruction of elbow flexion. Tapping the intercostal nerve-re...

journal_title：Neuroscience letters

authors： Kanamaru A,Suzuki S,Sibuya M,Homma I,Sai K,Hara T

更新日期：1993-10-14 00:00:00

abstract：:Mutations in coding exons or exon 10 5'-splice-site of the gene for microtubule-associated protein tau can cause chromosome 17-linked frontotemporal dementia and parkinsonism (FTDP-17). We sequenced the 11 coding exons plus exon-intron boundaries of the tau gene in 15 cases of progressive supranuclear palsy (PSP), and...

journal_title：Neuroscience letters

authors： Bonifati V,Joosse M,Nicholl DJ,Vanacore N,Bennett P,Rizzu P,Fabbrini G,Marconi R,Colosimo C,Locuratolo N,Stocchi F,Bonuccelli U,De Mari M,Wenning G,Vieregge P,Oostra B,Meco G,Heutink P

更新日期：1999-10-15 00:00:00