Heat pain threshold and tolerance show no left-right perceptual differences at complementary sites of the human forearm.

Abstract:

:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain threshold and pain tolerance did not differ within and across forearm sites. Experimenters addressing heat pain threshold and tolerance in healthy volunteers may freely choose and change stimulation sites on both volar forearms, without the risk of confounding site effects on dependent variables. This data completes previous reports on side effects by analyzing the effect of site on the forearm for both heat pain threshold and tolerance. The absence of side and site effects may contribute to setting a more secure basis for assessments of laterality effects of painful stimulation.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

doi

10.1016/j.neulet.2008.05.084

subject

Has Abstract

pub_date

2008-08-08 00:00:00

pages

309-13

issue

3

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(08)00749-0

journal_volume

440

pub_type

杂志文章,随机对照试验
  • A selective distribution pattern of different opiate receptors in certain areas of rat brain as revealed by in vitro autoradiography.

    abstract::A differential localization of binding sites in the rat brain for [3H]D-Ala2,Leu5-enkephalin ([3H]DADL) and [3H]etorphine ([3H]Eto) was been demonstrated by an in vitro autoradiography technique. Labeling with [3H]DADL was found predominantly in septum and paraventricular nuclei of hypothalamus, whereas [3H]Eto labeli...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(81)90368-2

    authors: Duka T,Schubert P,Wüster M,Stoiber R,Herz A

    更新日期:1981-01-20 00:00:00

  • Effects of voluntary exercise on anxiety-like behavior and voluntary morphine consumption in rat pups borne from morphine-dependent mothers during pregnancy.

    abstract::Exposure to morphine during pregnancy produced long-term effects in offspring behaviors. Recent studies have shown that voluntary exercise decreases the severity of anxiety behaviors in both morphine-dependent and withdrawn rats. Thus, the aims of the present study were to examine whether maternal exercise decreases p...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.06.026

    authors: Haydari S,Miladi-Gorji H,Mokhtari A,Safari M

    更新日期:2014-08-22 00:00:00

  • Hesperidin downregulates kinases lrrk2 and gsk3β in a 6-OHDA induced Parkinson's disease model.

    abstract::The depletion of dopamine in the striatum region and Lewy bodies are the hallmark characteristics of Parkinson's disease. The pathology also includes the upregulation of various Parkinson's disease (PARK) genes and kinases. Two such kinases, LRRK2 and GSK-3β have been directly implicated in the formation of tau and al...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2020.135426

    authors: Kesh S,Kannan RR,Sivaji K,Balakrishnan A

    更新日期:2021-01-01 00:00:00

  • Sex and regional differences in effects of chronic intermittent ethanol exposure on subsequent excitotoxic challenges in hippocampal slice cultures.

    abstract::The organotypic hippocampal slice culture technique was used to study how the effects of repeated ethanol withdrawal might differ between males and females at the cellular level, including potential modulation of subsequent insults. A chronic intermittent ethanol (CIE) exposure paradigm was employed, with 3 days of ex...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.05.011

    authors: Walls SA,Rosenwasser AM,Devaud LL

    更新日期:2013-08-29 00:00:00

  • BET differences among simultaneous evoked frequency band responses during early-stage visual processing distinguish schizophrenia from healthy subjects.

    abstract::In this work, we attempt to extend to the schizophrenia's research the evidence that different frequency bands may emerge from different sources during early-stage visual processing, in a mental state-specific manner, while subjects are passively viewing a visual stimulus. We applied standard pattern reversal stimulat...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.10.109

    authors: González-Hernández JA,Pita-Alcorta C,Castañeda H,Trujillo-Barreto N,Scherbaum WA

    更新日期:2009-01-23 00:00:00

  • Lophozozymus pictor toxin: a potent inhibitor of synaptosomal GABA uptake.

    abstract::A partially purified toxin obtained from the coral reef crab, Lophozozymus pictor was found to be a potent inhibitor of Na+-dependent [14C]-GABA uptake by rat brain synaptosomes. Inhibition was potentiated in the presence of external K+. The I50 value for the toxin was found to be in the region of 10 microgram/ml at a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(79)96171-8

    authors: Tan CH,Abkowitz SJ

    更新日期:1979-10-01 00:00:00

  • Lithium and oxidative stress lessons from the MPTP model of Parkinson's disease.

    abstract::Lithium has been successfully employed therapeutically for treatment of bipolar depressive illness; however, its mechanism of action is poorly understood. Recently, it has been demonstrated by us that lithium can prevent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) dopaminergic neurotoxicity in mice. From analy...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.03.055

    authors: Arraf Z,Amit T,Youdim MB,Farah R

    更新日期:2012-05-10 00:00:00

  • Improvement of cobalt-transport in axons by complexing agents.

    abstract::The use of the cobalt technique is limited by the fact that cobaltous ions travel within axons for a shorter distance than do other intracellular markers. In the present experiments different organic cobaltous complexes were tested in the rat's sciatic nerve. Cobaltous complexes containing ornithine, threonine, lysine...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(78)90074-5

    authors: Gallyas F,Lénárd L,Lázár G

    更新日期:1978-09-01 00:00:00

  • MTHFR C677T and A1298C polymorphisms may contribute to the risk of Parkinson's disease: A meta-analysis of 19 studies.

    abstract::The 5,10-methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be a candidate gene for susceptibility to Parkinson's disease (PD), but results of different studies are conflicting. Here, we conducted a meta-analysis of published case-control studies to evaluate the association between MTHFR C677T and A...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.neulet.2017.10.060

    authors: Liu L,Zhang L,Guo L,Yu Q,Li H,Teng J,Xie A

    更新日期:2018-01-01 00:00:00

  • Early rapid rise in EAAT2 expression follows the period of maximal seizure susceptibility in human brain.

    abstract::Seizures are relatively common in the first weeks of life and can have lasting effects on brain development due to glutamate excitotoxicity. The excitatory amino acid transporter 2 (EAAT2) is responsible for the majority of glutamate uptake in the brain and mice with this gene deleted die from seizures. Therefore, we ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.10.037

    authors: Lauriat TL,Schmeidler J,McInnes LA

    更新日期:2007-01-22 00:00:00

  • Neonatal transection of the corpus callosum affects paw preference lateralization of adult Swiss mice.

    abstract::In the present work, the hypothesis that the ontogenetic development of the corpus callosum (CC) affects the establishment of behavioral lateralization was tested by studying paw preference performance in adult Swiss mice that were subjected to mid-sagittal transection of the CC on the first postnatal day. Magnitude a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00746-8

    authors: Manhães AC,Krahe TE,Caparelli-Dáquer E,Ribeiro-Carvalho A,Schmidt SL,Filgueiras CC

    更新日期:2003-09-11 00:00:00

  • Chronic activation of protein kinase C by phorbol ester reduces calcium channel expression in chick sympathetic neurons.

    abstract::Chronic activation of protein kinase C (PKC) has been implicated in regulation of Ca2+ entry responsible for normal development of transmitter properties in cultured sympathetic neurons. The idea that PKC alters the expression of Ca2+ channels was tested using phorbol 12,13-dibutyrate (PDB) which activates PKC and als...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00427-8

    authors: Przywara DA,Zhong H,Kulkarni JS,Anderson GF,Wakade AR

    更新日期:1997-06-27 00:00:00

  • A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model.

    abstract::A free radical scavenger edaravone is clinically used in Japan for acute stroke, and several basic researches have carefully examined the mechanisms of edaravone's protective effects. However, its actions on pro-inflammatory responses under stroke are still understudied. In this study, we subjected adult male Sprague-...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.08.048

    authors: Fujiwara N,Som AT,Pham LD,Lee BJ,Mandeville ET,Lo EH,Arai K

    更新日期:2016-10-28 00:00:00

  • Seizure-mediated accumulation of the beta subunit of Ca2+/calmodulin-dependent protein kinase II in nuclei of mouse brain cells.

    abstract::We identified a 45-kDa protein by 2D electrophoresis that was enhanced following pentylenetetrazol (PTZ)-mediated seizures. Mass-spectrography of this protein revealed the beta subunit of Ca2+/calmodulin-dependent protein kinase II (CaMKIIbeta), although no evidence for increase in bulk CaMKIIbeta transcripts was obta...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00025-3

    authors: Matsu-ura T,Nakadai T,Oda Y,Nagasu T,Mikoshiba K,Tamura TA

    更新日期:2002-04-12 00:00:00

  • Neurons in the cortical taste area receive nociceptive inputs from the whole body as well as the oral cavity in the rat.

    abstract::Almost all mechanoreceptive neurons in the cortical taste area (CTA) of the rat had receptive fields (RFs) in the oral cavity, except for a few neurons at the border with the primary somatosensory area that had RFs on the contralateral rhinarium or upper lip. About one-third of the mechanoreceptive neurons with RFs in...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00099-x

    authors: Ogawa H,Wang XD

    更新日期:2002-04-05 00:00:00

  • Genetic variation in CTNNA3 encoding alpha-3 catenin and Alzheimer's disease.

    abstract::Linkage studies have implicated a broad region on chromosome 10q in Alzheimer's disease (AD). A recent genetic association study has provided evidence that polymorphism in the gene encoding alpha-3 catenin (CTNNA3, referred to previously as VR22 and also known as alpha-T catenin) may underlie linkage signals. Here, to...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.01.032

    authors: Blomqvist ME,Andreasen N,Bogdanovic N,Blennow K,Brookes AJ,Prince JA

    更新日期:2004-04-01 00:00:00

  • Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes.

    abstract::Fractalkine is a CX3C chemonkine that appears to be a neuron-to-microglia signal molecule in the central nervous system. We studied the expression of fractalkine in normal human astrocytes in culture, by using semi-quantitative reverse transcription-polymerase chain reaction and enzyme-linked immunosorbent assay. We f...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01699-8

    authors: Yoshida H,Imaizumi T,Fujimoto K,Matsuo N,Kimura K,Cui X,Matsumiya T,Tanji K,Shibata T,Tamo W,Kumagai M,Satoh K

    更新日期:2001-05-04 00:00:00

  • Early-life epileptiform discharges exert both rapid and long-lasting effects on AMPAR subunit composition and distribution in developing neurons.

    abstract::The perinatal period of brain is characterized by dynamic changes in structure and high propensity for epilepsy. Animal models have shown that alterations of AMPA receptor (AMPAR) assembly or function may be related to seizure-induced cell damage, long-lasting impairments in brain development and seizure threshold. Ho...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.08.006

    authors: Jiang Q,Wang J,Wu Y,Wu X,Qin J,Jiang Y

    更新日期:2008-10-17 00:00:00

  • Toxicity of N-acetylaspartylglutamate and its protection by NMDA and non-NMDA receptor antagonists.

    abstract::N-Acetylaspartylglutamate (NAAG) is a dipeptide, and has been demonstrated to be a putative neurotransmitter in the brain. We hereby report the toxicity of NAAG in sagittal slices of mouse brain, in vitro, which is prevented by both N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists. Incubation of mouse bra...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90368-4

    authors: Pai KS,Ravindranath V

    更新日期:1991-05-13 00:00:00

  • An atypical diencephalic nucleus in actinopterygian fishes: visual connections and sporadic phylogenetic distribution.

    abstract::Nucleus rostrolateralis is a distinctive diencephalic nucleus in some ray-finned fishes. In the osteoglossomorph Pantodon, it is a large ovoid nucleus with visual system connections. A topologically and cytoarchitectonically similar nucleus has been found in six species of non-osteoglossomorph fishes, two species of g...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00411-4

    authors: Saidel WM,Butler AB

    更新日期:1997-06-20 00:00:00

  • Respiratory patterning of the rat olfactory bulb unit activity: nasal versus tracheal breathing.

    abstract::To assess the role of nasal/tracheal (N/T) breathing in the respiratory patterning of the olfactory bulb (OB) neurons, the activity of 21 units was recorded in 6 anesthetized rats set with a cannula enabling reversible tracheotomy: the rats could inhalate either through nasal pathways or through trachea directly. Shif...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90457-k

    authors: Ravel N,Pager J

    更新日期:1990-07-31 00:00:00

  • Antinociception from the administration of beta-endorphin into the periaqueductal gray of rat is enhanced while that of morphine is inhibited by barbiturate anesthesia.

    abstract::Pentobarbital anesthesia causes about a 10-fold increase in the antinociceptive potency of beta-endorphin microinjected into the periaqueductal gray (PAG) region of the rat brain. The antinociceptive response to PAG morphine was markedly attenuated during anesthesia, but returned as the rats regained consciousness. As...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90063-d

    authors: Smith DJ,Robertson B,Monroe PJ

    更新日期:1992-11-09 00:00:00

  • GSM radiation triggers seizures and increases cerebral c-Fos positivity in rats pretreated with subconvulsive doses of picrotoxin.

    abstract::This study investigated the effects of mobile-phone-type radiation on the cerebral activity of seizure-prone animals. When rats transformed into an experimental model of seizure-proneness by acute subconvulsive doses of picrotoxin were exposed to 2 h GSM-modulated 900 MHz radiation at an intensity similar to that emit...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.12.082

    authors: López-Martín E,Relova-Quinteiro JL,Gallego-Gómez R,Peleteiro-Fernández M,Jorge-Barreiro FJ,Ares-Pena FJ

    更新日期:2006-05-01 00:00:00

  • Human mesenchymal stem cells improve the neurodegeneration of femoral nerve in a diabetic foot ulceration rats.

    abstract::Neuropathy is observed in 50% of diabetic patients with diabetic foot. This study attempted to explore the potential role of human mesenchymal stem cells-umbilical cord blood (hMSCs-UC) in femoral nerve (FN) neuropathy. The model rats were established by one time administration of streptozotocin and empyrosis on the d...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.04.038

    authors: Xia N,Xu JM,Zhao N,Zhao QS,Li M,Cheng ZF

    更新日期:2015-06-15 00:00:00

  • Pre-attentive processing of auditory patterns in dyslexic human subjects.

    abstract::It has been hypothesized that auditory temporal processing plays a major role in the aetiology of dyslexia. Event-related brain potentials (mismatch negativity, MMN) of auditory temporal processing were assessed in 15 dyslectic adults and 20 controls. A complex tonal pattern was used where the difference between stand...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00785-5

    authors: Schulte-Körne G,Deimel W,Bartling J,Remschmidt H

    更新日期:1999-11-26 00:00:00

  • Combined behavioral studies and in vivo imaging of inflammatory response and expression of mGlu5 receptors in schnurri-2 knockout mice.

    abstract::Schnurri-2 (Shn-2) knockout (KO) mice have been proposed as a preclinical neuroinflammatory schizophrenia model. We used behavioral studies and imaging markers that can be readily translated to human populations to explore brain effects of inflammation. Shn-2 KO mice and their littermate control mice were imaged with ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.10.037

    authors: Choi JK,Zhu A,Jenkins BG,Hattori S,Kil KE,Takagi T,Ishii S,Miyakawa T,Brownell AL

    更新日期:2015-11-16 00:00:00

  • Plasma gelsolin and matrix metalloproteinase 3 as potential biomarkers for Alzheimer disease.

    abstract::Gelsolin (GSN) levels and matrix metalloproteinase 3 (MMP3) activity have been found to be altered in the plasma in patients with Alzheimer disease (AD). The aim of this study was to determine whether a combination of these proteins with clinical data is specific and sensitive enough for AD diagnosis. In 113 non-demen...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.04.014

    authors: Peng M,Jia J,Qin W

    更新日期:2015-05-19 00:00:00

  • Hippocampal cystathionine beta synthase in young and aged mice.

    abstract::Cystathionine beta synthase (CBS) is the main contributor to the production of hydrogen sulfide (H2S) in the brain. Exogenously administered H2S has been reported to protect neurons against hypoxic injury, ischemia and LPS-induced neuro-inflammation and in the facilitating of long term potentiation (LTP). Dysregulatio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.01.049

    authors: Bruintjes JJ,Henning RH,Douwenga W,van der Zee EA

    更新日期:2014-03-20 00:00:00

  • Colocalization of prolactin- and dynorphin-like substances in a neuronal population of the rat lateral hypothalamus.

    abstract::Using an antiserum (AS) raised against dynorphin B (DYN B), we revealed immunoreactive neurons in different nuclei of the rat hypothalamus as well as a population of neurons scattered in the lateral areas of the posterior hypothalamus. This population corresponds to that previously shown to be specifically recognized ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90447-s

    authors: Griffond B,Deray A,Fellmann D,Ciofi P,Croix D,Bugnon C

    更新日期:1993-06-25 00:00:00

  • Topographical distribution of pinprick and warmth thresholds to CO2 laser stimulation on the human skin.

    abstract::We studied the topographical distribution of laser sensory thresholds on the human hairy skin, using a small laser beam for pinprick and a large beam for warmth sensations. The threshold for pinprick sensation correlated positively with the distance from the brain, suggesting that Adelta nociceptors, the fibers which ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01038-7

    authors: Agostino R,Cruccu G,Iannetti G,Romaniello A,Truini A,Manfredi M

    更新日期:2000-05-12 00:00:00