Topographical distribution of pinprick and warmth thresholds to CO2 laser stimulation on the human skin.

Abstract:

:We studied the topographical distribution of laser sensory thresholds on the human hairy skin, using a small laser beam for pinprick and a large beam for warmth sensations. The threshold for pinprick sensation correlated positively with the distance from the brain, suggesting that Adelta nociceptors, the fibers which convey pinprick sensation, are more dense at proximal than at distal body sites. This finding adds information to skin biopsy studies of epidermal free nerve endings which showed a similar gradient, but could not differentiate small myelinated from unmyelinated fiber afferents. Possibly because of a diffuse low density of warmth receptors, laser warmth thresholds showed no trend.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Agostino R,Cruccu G,Iannetti G,Romaniello A,Truini A,Manfredi M

doi

10.1016/s0304-3940(00)01038-7

keywords:

subject

Has Abstract

pub_date

2000-05-12 00:00:00

pages

115-8

issue

2

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(00)01038-7

journal_volume

285

pub_type

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