Abstract:
:Contact heat evoked potentials (CHEPs) have been difficult to elicit due to slow temperature rise times. A recently developed heat-foil technology was used to elicit pain and CHEPs. Two groups of subjects were separately stimulated at the left arm with contact heat via one fast-acting (70 degrees C/s) heat-foil thermode. A set of CHEPs was recorded, each at three subjective intensities: warm; slight; and moderate pain. In CHEPs, the 3D topography exhibited four components: T3-T4/N450; Cz/N550; Cz/P750; and Pz/P1000. A vertex topography map was observed in the late Cz/N550-Cz/P750 and parietal topography in the very-late Pz/P1000 components. Consistent statistical values in the peak latencies and amplitudes were noted between consecutive investigations. The correlation between the pain intensity ratings and the major Cz/P750 amplitudes was highly significant in each study. Our validity tests suggested CHEPs to be useful for research and clinical applications in studying human pain activation related to thermal and nociceptive pathways.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Chen AC,Niddam DM,Arendt-Nielsen Ldoi
10.1016/s0304-3940(01)02374-6keywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
79-82issue
2eissn
0304-3940issn
1872-7972pii
S0304394001023746journal_volume
316pub_type
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