Axotomy induces MHC class I antigen expression on rat nerve cells.

Abstract:

:Immunomorphological staining demonstrates that class I major histocompatibility complex (MHC)-coded antigen expression can be selectively induced on otherwise class I-negative rat nerve cells by peripheral axotomy. Induction of class I as well as class II antigen expression was simultaneously seen on non-neural cells in the immediate vicinity of the injured nerve cells. As nerve regeneration after axotomy includes growth of new nerve cell processes and formation of new nerve cell contacts, the present findings raise the question of a role for MHC-coded molecules in cell-cell interactions during nerve cell growth.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Maehlen J,Schröder HD,Klareskog L,Olsson T,Kristensson K

doi

10.1016/0304-3940(88)90733-1

subject

Has Abstract

pub_date

1988-09-23 00:00:00

pages

8-13

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(88)90733-1

journal_volume

92

pub_type

杂志文章
  • The uptake and transport behavior of berberine in Coptidis Rhizoma extract through rat primary cultured cortical neurons.

    abstract::The objective of this study was to investigate whether berberine in Coptidis Rhizoma extract could be transported in primary cultured cerebral neurons and to study the uptake and transport behavior of berberine through the neurons. The present results showed that the uptake of berberine by the neurons increased linear...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.12.050

    authors: Wang X,Xing D,Wang W,Lei F,Su H,Du L

    更新日期:2005-05-06 00:00:00

  • The locus of optic nerve head representation in the retinotopic projection over nucleus geniculatus lateralis ventralis and nucleus griseum tectalis in the chick also lacks a retinal projection.

    abstract::Recently we have demonstrated the presence of a gap in the avian retinotectal projection, that corresponds with the locus of retinotopic representation of the elongated optic nerve head. The present report describes an equivalent gap in the optic neuropiles of the avian ventral geniculate nucleus and griseum tectalis ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90424-7

    authors: Puelles L,Martinez S,Martinez-de-la-Torre M

    更新日期:1988-02-15 00:00:00

  • Genetic deletion of Fatty Acid Amide Hydrolase results in improved long-term outcome in chronic autoimmune encephalitis.

    abstract::The enzyme Fatty Acid Amide Hydrolase (FAAH) is a key regulator of the endogenous levels of a family of biologically active lipid mediators, the fatty acid amides. These include anandamide, oleoyl ethanolamide and palmitoyl ethanolamide, and their effects are mediated by a variety of downstream targets including canna...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.04.090

    authors: Webb M,Luo L,Ma JY,Tham CS

    更新日期:2008-07-04 00:00:00

  • The benzodiazepine triazolam phase-shifts circadian activity rhythms in a diurnal primate, the squirrel monkey (Saimiri sciureus).

    abstract::Triazolam can shift the phase of circadian rhythms in hamsters recorded in constant light or dark. This effect is apparently mediated by physical activity stimulated by the drug. We examined whether triazolam can shift the phase of circadian rhythms in a diurnal primate, the squirrel monkey, that is sedated by triazol...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90814-a

    authors: Mistlberger RE,Houpt TA,Moore-Ede MC

    更新日期:1991-03-11 00:00:00

  • Neuromelanic pigment in substantia nigra neurons of rats and dogs.

    abstract::The presence of neuromelanic pigment in neurons of the rat substantia nigra (SN) is a matter of controversy. The presence of neuromelanin in the SN of 15--24-month-old rats was investigated by electron microscopy (EM) and the findings compared to the morphology and distribution of neuromelanin in SN of dogs. In the ra...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90614-2

    authors: DeMattei M,Levi AC,Fariello RG

    更新日期:1986-12-03 00:00:00

  • Association of BRD2 polymorphisms with photoparoxysmal response.

    abstract::A trait locus for electroencephalographic photoparoxysmal response (PPR) has been mapped to the chromosomal region 6p21 near a susceptibility locus for juvenile myoclonic epilepsy (JME). Linkage disequilibrium mapping revealed strong associations between JME and polymorphisms of the gene encoding the bromodomain-conta...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.02.026

    authors: Lorenz S,Taylor KP,Gehrmann A,Becker T,Muhle H,Gresch M,Tauer U,Sander T,Stephani U

    更新日期:2006-05-29 00:00:00

  • Cerebrospinal fluid homovanillic acid levels are not reduced in early corticobasal degeneration.

    abstract::To investigate the contribution of nigral degeneration to the development of parkinsonism in the early stages of corticobasal degeneration (CBD), we measured the cerebrospinal fluid (CSF) levels of homovanillic acid (HVA) in patients with early CBD (n = 5), and compared the levels with those in patients with early Par...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00181-5

    authors: Kanemaru K,Mitani K,Yamanouchi H

    更新日期:1998-04-03 00:00:00

  • Improvement of cobalt-transport in axons by complexing agents.

    abstract::The use of the cobalt technique is limited by the fact that cobaltous ions travel within axons for a shorter distance than do other intracellular markers. In the present experiments different organic cobaltous complexes were tested in the rat's sciatic nerve. Cobaltous complexes containing ornithine, threonine, lysine...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(78)90074-5

    authors: Gallyas F,Lénárd L,Lázár G

    更新日期:1978-09-01 00:00:00

  • Release of immunoreactive beta-endorphin from synaptosome-enriched fraction of rat hypothalami.

    abstract::Immunoreactive beta-endorphin is localized mainly in the synaptosome-enriched subcellular fraction from rat hypothalami. In this report, we demonstrate that release of immunoreactive beta-endorphin from the synaptosome-enriched subcellular fraction is increased by 150% in a medium containing high potassium. This stimu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(80)90259-1

    authors: Fukata J,Nakai Y,Imura H

    更新日期:1980-08-01 00:00:00

  • The nef protein of the human immunodeficiency virus type 1 (HIV-1) inhibits a large-conductance potassium channel in human glial cells.

    abstract::The Nef protein of human immunodeficiency virus type 1 (HIV-1) is abundantly expressed in HIV-1-infected astrocytes and shares amino acid sequence homology to alpha-scorpion toxins which bind to potassium channels. Here we report effects of recombinant Nef and alpha-scorpion toxins on membrane potassium transport in h...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00495-9

    authors: Kort JJ,Jalonen TO

    更新日期:1998-07-17 00:00:00

  • Genetic studies in Parkinson's disease with an alpha-synuclein/NACP gene polymorphism in Japan.

    abstract::Dinucleotide repeat polymorphism has been observed in the promoter of the alpha-synuclein (alpha-SYN)/NAC precursor protein (NACP) gene. Alpha-SYN/NACP allele 3 (described by Xia et al. (Ann. Neurol., 40 (1996) 207), equivalent to allele 1 described by Krüger et al. (Ann. Neurol. 45 (1999) 611) is reported to be signi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01557-9

    authors: Izumi Y,Morino H,Oda M,Maruyama H,Udaka F,Kameyama M,Nakamura S,Kawakami H

    更新日期:2001-03-09 00:00:00

  • Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia.

    abstract::The aim of this study was to investigate the relationship between the functional C957T single-nucleotide polymorphism of the dopamine D2 receptor (DRD2) gene and the risk for schizophrenia. We therefore conducted a case-control association study of 188 Finnish schizophrenia patients meeting the DSM-IV criteria and 384...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.08.041

    authors: Hänninen K,Katila H,Kampman O,Anttila S,Illi A,Rontu R,Mattila KM,Hietala J,Hurme M,Leinonen E,Lehtimäki T

    更新日期:2006-10-30 00:00:00

  • Galanin and bethanechol appear to activate the same inwardly rectifying potassium current in mudpuppy parasympathetic neurons.

    abstract::Galanin- and bethanechol-activated whole cell currents were studied in dissociated mudpuppy parasympathetic neurons kept in 12.5 mM KCl. The bethanechol-induced current was reduced when generated during a galanin-induced current. The galanin and bethanechol currents reversed at -45 mV and exhibited inward rectificatio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90675-w

    authors: Parsons RL,Merriam LA

    更新日期:1992-06-08 00:00:00

  • Lesion patterns of vasoactive intestinal polypeptide-containing neurons in the myenteric plexus induced by clamping or transsection of rat jejunum.

    abstract::The acute reactions of vasoactive intestinal polypeptide (VIP)-containing neurons in the myenteric plexus of the rat jejunum in response to circumferential clamping or transection/reanastomosis were evaluated in a detailed time course of up to ten days. Whereas in sham-operated controls VIP immunostaining was confined...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90007-v

    authors: Trudrung P,Waldner H,Sklarek J,Nitsch C

    更新日期:1990-02-16 00:00:00

  • Differential regulation of SC1/PRDM4 and PRMT5 mediated protein arginine methylation by the nerve growth factor and the epidermal growth factor in PC12 cells.

    abstract::During neuronal development, the neuroepithelial stem cells (NSCs) initially undergo proliferative divisions, later switching to neurogenic ones whereby one NSC and a post-mitotic neuron are generated. We recently showed that a member of the PRDM family of transcriptional regulators, PRDM4/SC1, recruits a type II prot...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.06.051

    authors: Chittka A

    更新日期:2013-08-29 00:00:00

  • The vanilloid receptor-1 is expressed in rat spinal dorsal horn astrocytes.

    abstract::The vanilloid receptor-1 (TRPV1), expressed by nociceptive fibers, is a transducer of thermal and chemical nociceptive messages. However, endogenous ligands excite TRPV1 receptors localized on central nociceptive terminals and interneurons. Using immunocytochemistry at the ultrastructural level, we show that TRPV1 is ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2003.12.051

    authors: Doly S,Fischer J,Salio C,Conrath M

    更新日期:2004-03-04 00:00:00

  • The effects of levodopa use on diffusion coefficients in various brain regions in Parkinson's disease.

    abstract::We aimed to evaluate the effects of l-dopa use on apparent diffusion coefficient (ADC) values of different brain regions in Parkinson's disease (PD) patients. Thirty-five subjects underwent magnetic resonance imaging (MRI), including 21 PD patients (13 men, 8 women; mean age, 63 years+/-8), and 14 sex and age-matched ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.02.022

    authors: Degirmenci B,Yaman M,Haktanir A,Albayrak R,Acar M,Caliskan G

    更新日期:2007-04-18 00:00:00

  • Co-localization of tyrosine hydroxylase and GABA immunoreactivities in human cortical neurons.

    abstract::Samples of human cerebral cortex were stained immunocytochemically for tyrosine hydroxylase (TH) and gamma-aminobutyric acid (GABA). TH-positive neurons were in small number and predominated in the deep infragranular layers V-VI contrasting with numerous GABA-positive neurons scattered in all layers. Co-localization o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90205-x

    authors: Trottier S,Geffard M,Evrard B

    更新日期:1989-11-20 00:00:00

  • Intracellular dyes mask immunoreactivity of hippocampal interneurons.

    abstract::The results of several studies have suggested that local circuit neurons, or interneurons, of area CA1 of hippocampus use gamma-aminobutyric acid (GABA) as their neurotransmitter. However, when these cells were labelled by intracellular dye injection, and examined immunocytochemically with antisera raised against GABA...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90237-1

    authors: Scharfman HE,Kunkel DD,Schwartzkroin PA

    更新日期:1989-01-02 00:00:00

  • Cntnap2 expression in the cerebellum of Foxp2(R552H) mice, with a mutation related to speech-language disorder.

    abstract::Foxp2(R552H) knock-in (KI) mice carrying a mutation related to human speech-language disorder exhibit impaired ultrasonic vocalization and poor Purkinje cell development. Foxp2 is a forkhead domain-containing transcriptional repressor that associates with its co-repressor CtBP; Foxp2(R552H) displays reduced DNA bindin...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.11.022

    authors: Fujita E,Tanabe Y,Momoi MY,Momoi T

    更新日期:2012-01-11 00:00:00

  • Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men.

    abstract::Tobacco smoke inhibits monoamine oxidase-B (MAO-B) activity in vitro and in vivo, suggesting that MAO-B inhibition is a possible contributing factor to tobacco smoke addiction. Thus, MAO-B is a possible candidate gene for predisposition to smoking. The TaqIB polymorphism for the Dopamine D2 Receptor gene (DRD2) has be...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.05.035

    authors: Costa-Mallen P,Costa LG,Checkoway H

    更新日期:2005-09-09 00:00:00

  • Changes of calcitonin gene-related peptide-like immunoreactivity in cerebrovascular nerve fibers in the dog after experimentally produced subarachnoid hemorrhage.

    abstract::After producing a model of subarachnoid hemorrhage (SAH) by a single injection of fresh autologous arterial blood into the cisterna magna in the dog, we immunohistochemically examined changes of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) in perivascular nerve fibers in the large pial arteries by u...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90302-9

    authors: Nozaki K,Kikuchi H,Mizuno N

    更新日期:1989-07-17 00:00:00

  • Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.

    abstract::Hypoxic-ischemic brain damage (HIBD) leads to acute death and chronic neurological dysfunction in neonates. To date, there is no satisfactory acknowledged strategy to provide neuroprotection completely. Verbascoside (VB) has been proved to possess antioxidative, anti aging and neuroprotective activities. The aim of th...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2019.134415

    authors: Wei W,Lu M,Lan X,Liu N,Wang H,Du J,Sun T,Li Y,Yu J

    更新日期:2019-10-15 00:00:00

  • Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.

    abstract::Expression levels of amyloid beta (Abeta)-degrading enzymes, insulin degrading enzyme (IDE) and neprilysin (NEP), were examined in transgenic mice with Alzheimer's disease-like neuropathology. After the development of first Abeta plaques in transgenic mice brain, cortical mRNA and protein levels of IDE were significan...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.04.025

    authors: Vepsäläinen S,Hiltunen M,Helisalmi S,Wang J,van Groen T,Tanila H,Soininen H

    更新日期:2008-06-20 00:00:00

  • Orthography effect on brain activities in the working memory process for phonologically ambiguous syllables: a functional magnetic resonance imaging study using Japanese speakers.

    abstract::English /l/ and /r/ sounds are not distinctive for Japanese speakers and they are loosely associated with corresponding graphemes. The purpose of this study was to investigate the brain activities in the memory process for the graphemes containing 'l' and 'r' in Japanese speakers. Two functional magnetic resonance ima...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)01201-6

    authors: Sumiyoshi C,Matsuo K,Kato C,Ozawa F,Takehara Y,Isoda H,Isogai S,Sakahara H,Nakai T

    更新日期:2003-01-09 00:00:00

  • Dynamin protein in stroke and vascular dementia.

    abstract::Damage to sub-cortical white matter is a key substrate of vascular dementia (VaD) leading to deficits in executive function and cognitive processing speed. Dynamin1 is a 100 kDa protein, accounting for 0.4% of the total brain protein, and has a central role in many intracellular processes such as synaptic vesicle traf...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.01.045

    authors: Mulugeta E,Vallortigara J,Francis PT,Hye A,Kalaria RN,Perry EK,Lovestone S,Ballard CG

    更新日期:2014-03-20 00:00:00

  • Aging impairs methamphetamine-induced free-running and anticipatory locomotor activity rhythms in rats.

    abstract::In the present experiment, under drinking of 0.01% methamphetamine (MA), young rats exhibited free-running locomotor rhythm ranging from 24.6 to 30.9 h period under light-dark cycle. In contrast, 24-month-old rats showed a low activity and did not exhibit MA-induced free-running rhythm. When MA was injected at a fixed...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90673-4

    authors: Shibata S,Minamoto Y,Ono M,Watanabe S

    更新日期:1994-05-19 00:00:00

  • Peptidergic innervation of the mammalian sinus nodes: vasoactive intestinal polypeptide, neurotensin, substance P.

    abstract::By the use of the peroxidase--antiperoxidase (PAP) technique in the sinus node of several mammalian species, vasoactive intestinal polypeptide (VIP), neurotensin (NT) and substance P (SP) immunoreactive structures were detected. VIP and NT as well as SP immunoreactive fibers were found in close association to the vasc...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(81)90146-4

    authors: Weihe E,Reinecke M

    更新日期:1981-11-04 00:00:00

  • Prepro-galanin messenger RNA levels are increased in rat locus coeruleus after treadmill exercise training.

    abstract::The effects of treadmill exercise training on prepro-galanin (GAL) and tyrosine hydroxylase (TH) gene expression in the locus coeruleus (LC) were examined. Male Fischer-344 rats (n=9) were assigned to 6 weeks of treadmill running. An additional group of animals comprised the sedentary home cage control group (n=9). Le...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01780-8

    authors: O'Neal HA,Van Hoomissen JD,Holmes PV,Dishman RK

    更新日期:2001-02-16 00:00:00

  • A refractory period after brief activation of mammalian skeletal muscle fibres.

    abstract::A two pulse technique was used to study the decay of mechanical activation in TTX poisoned mouse extensor digitorum longus (EDL) and soleus muscle fibres. A two microelectrode point voltage clamp technique was used with visual endpoint determination of the threshold potential for activation. The excitatory effect of a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(79)96152-4

    authors: Dulhunty AF

    更新日期:1979-10-01 00:00:00