Electrical stimulation of visceral afferent pathways in the pelvic nerve increases c-fos in the rat lumbosacral spinal cord.

Abstract:

:Electrical stimulation (20-35 Hz, 2-5 V, 1.5 h) of the pelvic nerve in urethane-anesthetized rats increased the expression of c-fos protein-immunoreactivity primarily in neurons in the L6-S1 segments of the spinal cord. The neurons were localized to areas receiving afferent input from the pelvic viscera including the superficial dorsal horn, the dorsal commissure, and lateral laminae V-VII in the region of the sacral parasympathetic nucleus. These experiments indicate that (1) electrical stimulation of abdominal nerves following surgical exposure is a useful method for tracing visceral afferent pathways and (2) afferent information from the pelvic viscera is received by neurons in specific areas of the dorsal horn.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Birder LA,Roppolo JR,Iadarola MJ,de Groat WC

doi

10.1016/0304-3940(91)90459-7

subject

Has Abstract

pub_date

1991-08-19 00:00:00

pages

193-6

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(91)90459-7

journal_volume

129

pub_type

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