Neovascularization of transplanted central nervous tissue suspensions: an immunohistochemical study with laminin.

Abstract:

:Neovascularization of the dissociated central nervous tissue transplanted into the lateral ventricle of the rat was studied using laminin immunohistochemistry. A very high immunoreactive response to laminin was demonstrated in the presumably newly formed vessels within the transplants and the graft-host borders. The growing tips and fine spike-like sprouts called 'streamers' were also highly stained with laminin immunoreactivity. In contrast, laminin immunoreactivity was negligible in the vessels in the host brain. Therefore, these results indicate that laminin may be utilized as a marker for the newly formed vessels in neural transplantations.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Shigematsu K,Kamo H,Akiguchi I,Kameyama M,Kimura H

doi

10.1016/0304-3940(89)90257-7

subject

Has Abstract

pub_date

1989-04-24 00:00:00

pages

18-23

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(89)90257-7

journal_volume

99

pub_type

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