VIP-induced stellation and immediate early gene expression in astrocytes: effects of dexamethasone.

abstract：:In order to clarify the mechanism of action of cerulenin analog, C75, known to suppress feeding behavior, food intake was measured in adult CD-1 male mice n=5 per group, treated i.p. with 10 and 20mg/kg of C75. Animals in both treatment groups had significantly lower 24h food consumption rate relative to the control g...

journal_title：Neuroscience letters

authors： Binienda ZK,Ross IA,Gough B,Riccio T,Kim CS,Ali SF

更新日期：2010-01-29 00:00:00

abstract：:Distributions of 25 motor axons to 60 intrafusal muscle fibers of 10 poles of monkey spindle were reconstructed from serial 1 micron thick transverse sections of lumbrical muscles. About 44% of motor axons co-innervated two or more types of intrafusal fiber. The (dynamic) bag1 fiber shared motor innervation with the (...

journal_title：Neuroscience letters

authors： Kucera J

更新日期：1985-01-07 00:00:00

abstract：:Olfactory bulb-protein tyrosine phosphatase (OB-PTP) is a receptor type PTPase dominantly expressed in olfactory bulb. Previously, we isolated and molecularly cloned a rat OB-PTP cDNA from an embryonal brain cDNA library. In the present study, we investigated its temporal and spatial gene expression by Northern blot a...

journal_title：Neuroscience letters

authors： Yahagi Y,Tagawa M,Tomoda T,Shirasawa T

更新日期：1996-06-21 00:00:00

abstract：:The present study aimed to validate a pictorial rating scale to evaluate the child's ability to produce grip forces. Thirty-seven children aged 3 to 6 years participated as subjects in this investigation. We used a tailor-made pictorial scale and a hand grip strength meter, as well as a Piaget's clinical interview aim...

journal_title：Neuroscience letters

authors： Defrasne Ait-Said E,Groslambert A,Courty D

更新日期：2007-06-13 00:00:00

abstract：:DSP-4[N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride] is a neurotoxin that depletes norepinephrine. The catecholaminergic system has been implicated in the regulation of blood glucose level. In the present study, the effect of DSP-4 administered intracerebroventricularly (i.c.v.) or intrathecally (i.t.) on...

journal_title：Neuroscience letters

authors： Park SH,Kim SS,Lee JR,Sharma N,Suh HW

更新日期：2016-05-04 00:00:00

abstract：:Samples of human cerebral cortex were stained immunocytochemically for tyrosine hydroxylase (TH) and gamma-aminobutyric acid (GABA). TH-positive neurons were in small number and predominated in the deep infragranular layers V-VI contrasting with numerous GABA-positive neurons scattered in all layers. Co-localization o...

journal_title：Neuroscience letters

authors： Trottier S,Geffard M,Evrard B

更新日期：1989-11-20 00:00:00

abstract：:Erythropoietin (EPO) has recently been shown to have a neuroprotective effect in animal models of traumatic brain injury (TBI). However, the precise mechanisms remain unclear. Cerebral inflammation plays an important role in the pathogenesis of secondary brain injury after TBI. We, therefore, tried to analyze how reco...

journal_title：Neuroscience letters

authors： Chen G,Shi JX,Hang CH,Xie W,Liu J,Liu X

更新日期：2007-10-02 00:00:00

abstract：:The present study has employed in vitro autoradiography to study the distribution and density of [3H]zolpidem binding sites, which are regarded as an index of ethanol-sensitive gamma-aminobutyric acid (GABA)A receptors, in the brains of alcohol-preferring Fawn-Hooded (FH) rats compared to non-alcohol preferring Wistar...

journal_title：Neuroscience letters

authors： Chen F,Rezvani A,Jarrott B,Lawrence AJ

更新日期：1997-12-05 00:00:00

abstract：:Recent discovery of pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene in Parkinson's disease (PD) patients in different ethnic groups have raised a hope of diagnostic screening and genetic counseling. We investigated the six most commonly reported mutations in LRRK2 gene among Indian PD patients, u...

journal_title：Neuroscience letters

authors： Punia S,Behari M,Govindappa ST,Swaminath PV,Jayaram S,Goyal V,Muthane UB,Juyal RC,Thelma BK

更新日期：2006-12-01 00:00:00

abstract：:An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been identified as an important cell surface marker to enrich the stem-like population in va...

journal_title：Neuroscience letters

authors： Dong L,Qi N,Ge RM,Cao CL,Lan F,Shen L

更新日期：2010-11-05 00:00:00

abstract：:The present study was carried out to examine whether γ-aminobutyric acid (GABA) receptor mechanisms are involved in the release of serotonin (5-hydroxytryptamine, 5-HT) in the subfornical organ (SFO) using intracerebral microdialysis techniques. Perfusion with the GABA receptor antagonists as well as agonists was perf...

journal_title：Neuroscience letters

authors： Takahashi M,Nomura M,Tanaka J

更新日期：2016-09-06 00:00:00

abstract：:Based on its proposed ability to block the effect of selective serotonin reuptake inhibitors (SSRIs) on the firing rate of serotonergic neurons, the 5-HT1A partial agonist/beta-adrenergic antagonist pindolol has been examined in clinical trials for its ability to enhance the efficacy of SSRIs. However, varying results...

journal_title：Neuroscience letters

authors： Rasmussen K,McCreary AC,Shanks EA

更新日期：2004-01-23 00:00:00

abstract：:To assess the neurotoxic properties of the glutamate agonist quisqualic acid (QA) in immature brain, we injected this compound (100 nmol QA/1 microliter) directly into the striatum of 7-day-old rats. QA produced neuronal necrosis and glial infiltration in 14 pups and reduced the size of the striatum and hippocampus on...

journal_title：Neuroscience letters

authors： Silverstein FS,Chen R,Johnston MV

更新日期：1986-10-30 00:00:00

abstract：:In vivo L-band electron spin resonance (ESR) system was used to measure the decay of nitroxide radicals in the living rat cerebrum containing a cortical area with an iron-induced epileptogenic region. Carbamoyl-PROXYL (3-carbamoyl-2,2,5,5-tetramethyl-1-pyrrolinyloxy) was injected intraperitoneally. The decay of nitrox...

journal_title：Neuroscience letters

authors： Komatsu M,Hiramatsu M,Yokoyama H,Willmore LJ

更新日期：1996-03-01 00:00:00

abstract：:Lumbar spinal cord explants, harvested from neonatal rat pups aged between postnatal day 0 (P0) and P7, were cultured for a period of 48 h in the chemically defined medium R(12) [17] (Romijn, H.J., van-Huijen, F., Wolters, P.S., Neurosci Biobehav Rev, 8 (1984) 301-334), embedded in a collagen matrix. The outgrowth int...

journal_title：Neuroscience letters

authors： Mouveroux JM,Lakke EA,Marani E

更新日期：2001-09-28 00:00:00

abstract：:The ability in vivo of the muscarinic agonist, pilocarpine, to increase phosphoinositol (PI) hydrolysis in lithium pretreated rats was investigated by measuring the accumulation of [(3)H]inositol phosphates (IP). As expected, 20 mg/kg s.c. pilocarpine, a muscarinic agonist, increased PI hydrolysis in the striatum, fro...

journal_title：Neuroscience letters

authors： Johnson MP,Kelly GM,Chamberlain M

更新日期：2000-05-05 00:00:00

abstract：:During hyperalgesia there is an enhancement of wind-up and the appearance of a novel wind-up of the A-fibre-mediated responses. We have examined if these phenomena are influenced by supraspinal mechanisms by analysing single motor unit activity in control and arthritic rats, either intact or acutely spinalised. Enhanc...

journal_title：Neuroscience letters

authors： Herrero JF,Cervero F

更新日期：1996-05-03 00:00:00

abstract：:Mutations in coding exons or exon 10 5'-splice-site of the gene for microtubule-associated protein tau can cause chromosome 17-linked frontotemporal dementia and parkinsonism (FTDP-17). We sequenced the 11 coding exons plus exon-intron boundaries of the tau gene in 15 cases of progressive supranuclear palsy (PSP), and...

journal_title：Neuroscience letters

authors： Bonifati V,Joosse M,Nicholl DJ,Vanacore N,Bennett P,Rizzu P,Fabbrini G,Marconi R,Colosimo C,Locuratolo N,Stocchi F,Bonuccelli U,De Mari M,Wenning G,Vieregge P,Oostra B,Meco G,Heutink P

更新日期：1999-10-15 00:00:00

abstract：:Amyotrophic Lateral Sclerosis (ALS) is a devastating and fatal neurodegenerative disease affecting approximately 30,000 individuals in the United States. The average age of onset is 55 years and progression of the disease is rapid with most patients dying of respiratory failure within 3-5 years. Currently available th...

journal_title：Neuroscience letters

authors： St Martin JL,Wang L,Kaprielian Z

更新日期：2020-01-18 00:00:00

abstract：:Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

journal_title：Neuroscience letters

authors： Peters J,Daum I

更新日期：2009-05-01 00:00:00

abstract：:Genome-wide analysis of miRNA expression has revealed increased levels of miR-144 in the brains of Alzheimer's disease (AD) patients. Nuclear factor erythroid 2-related factor 2 (NRF2), a potential target of miR-144, is a central regulator of antioxidant response, and plays an important role in glutathione (GSH) biosy...

journal_title：Neuroscience letters

authors： Zhou C,Zhao L,Zheng J,Wang K,Deng H,Liu P,Chen L,Mu H

更新日期：2017-08-10 00:00:00

abstract：:Using a new polyclonal antibody against prostacyclin (PGI2)-synthase this enzyme was shown to be present in neuronal cells of bovine, rat and human brain, most abundantly in Purkinje cells of the cerebellum and cortical neurons, but not in glial cells. Western blots confirmed the specificity of the antibody and applie...

journal_title：Neuroscience letters

authors： Mehl M,Bidmon HJ,Hilbig H,Zilles K,Dringen R,Ullrich V

更新日期：1999-08-27 00:00:00

abstract：:Using organotypic hippocampal slice cultures we have investigated the actions of Interleukin-1 (IL-1) in a number of injury paradigms. Low concentrations of IL-1 potentiated hypoxia-induced neurodegeneration whilst high concentrations had no effect. In contrast, higher concentrations of IL-1 were strongly neuroprotect...

journal_title：Neuroscience letters

authors： Pringle AK,Niyadurupola N,Johns P,Anthony DC,Iannotti F

更新日期：2001-06-01 00:00:00

abstract：:Whole-cell and single channel recordings were used to characterize an intermediate conductance calcium-activated potassium (KCa) channel in sensory neurons of the nodose ganglion. From a -80 mV holding potential, the total outward current in these neurons was increased when extracellular calcium was raised from 0.02 t...

journal_title：Neuroscience letters

authors： Hay M,Kunze DL

更新日期：1994-02-14 00:00:00

abstract：:The endosome/lysosome system in the nervous system is critically important for a variety of neuronal functions such as neurite outgrowth, retrograde transport, and synaptic plasticity. In neurons, the endosome/lysosome system is crucial for the activity-dependent internalization of membrane proteins and contributes to...

journal_title：Neuroscience letters

authors： Tsuruta F,Dolmetsch RE

更新日期：2015-09-25 00:00:00

abstract：:The N-Methyl-D-Aspartate Receptors (NMDARs) are heteromeric cation channels involved in learning, memory, and synaptic plasticity, and their dysregulation leads to various neurodegenerative disorders. Recent evidence has shown that apart from the GluN1/GluN2A and GluN1/GluN2B diheteromeric ion channels, the NMDAR also...

journal_title：Neuroscience letters

authors： Cheriyan J,Balsara RD,Hansen KB,Castellino FJ

更新日期：2016-03-23 00:00:00

abstract：:The effect of electroshock on the brain levels of somatostatin mRNA were evaluated by in situ hybridization using a selective oligonucleotide probe. Rats were submitted to single or repeated (7 days, one session for each day) sessions of electroshock. There was a marked increase of the expression of somatostatin mRNA ...

journal_title：Neuroscience letters

authors： Passarelli F,Orzi F

更新日期：1993-04-30 00:00:00

abstract：:The effects of the N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists MK-801 and NBQX, respectively, on salivary secretion and retching induced by vagal stimulation were studied in decerebrate dogs. Vagal stimulation induced an increase in salivary secretion and fictive retching. Intra-4th ventricular appli...

journal_title：Neuroscience letters

authors： Furukawa N,Hatano M,Fukuda H,Koga T

更新日期：1998-12-11 00:00:00

abstract：:Excessive activation of the N-methyl-D-aspartate (NMDA) receptor-channel complex has been implicated as one of the mechanisms by which ischemia-induced neuronal damage is mediated. Elevated glycine levels during ischemia may contribute to damage mediated by the NMDA receptor as glycine binding potentiates NMDA respons...

journal_title：Neuroscience letters

authors： Wood ER,Bussey TJ,Phillips AG

更新日期：1992-09-28 00:00:00

abstract：:The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

journal_title：Neuroscience letters

authors： Frotscher M,Wagner A,Misgeld U

更新日期：1983-07-29 00:00:00