Retrograde labeling of striato-nigral neurons in the rat by three different tracers.

abstract：:Aripiprazole, a novel atypical antipsychotic drug, can significantly increase dopamine (DA) levels in the prefrontal cortex of rats, but only at low doses below 1mg/kg. The aim of the present work was to test the effect of aripiprazole (0, 0.1, 0.3, 3 and 30 mg/kg, i.p.) on extracellular levels of monoamines in the pr...

journal_title：Neuroscience letters

authors： Zocchi A,Fabbri D,Heidbreder CA

更新日期：2005-10-28 00:00:00

abstract：:Many studies have shown that acupuncture can contribute to the biochemical balance in the central nervous system and maintenance or recovery of homeostasis. It is well known that chronic administration of ethanol may produce depletion or sensitization of extracellular dopamine levels in the nucleus accumbens. The pres...

journal_title：Neuroscience letters

authors： Zhao RJ,Yoon SS,Lee BH,Kwon YK,Kim KJ,Shim I,Choi KH,Kim MR,Golden GT,Yang CH

更新日期：2006-02-27 00:00:00

abstract：:Neuronal apoptosis sculpts the developing brain, and nearly all identified classes of neurons seem to be produced "in excess" during development. FoxO transcription factors regulate apoptosis in vitro in deprived of neurotrophins. It is unknown if FoxO3a is involved in the development of neurons. Here, we report a rol...

journal_title：Neuroscience letters

authors： Peng K,Li Y,Long L,Li D,Jia Q,Wang Y,Shen Q,Tang Y,Wen L,Kung HF,Peng Y

更新日期：2010-10-29 00:00:00

abstract：:Nociceptin/orphanin FQ (NC) and its receptor (OP(4)) have been implicated in the regulation of various functions including nociception. [Nphe(1)]NC(1-13)NH(2) (Nphe) is a selective OP(4) antagonist which prevents the pronociceptive effects of supraspinal NC and causes per se a naloxone-insensitive antinociceptive effe...

journal_title：Neuroscience letters

authors： Di Giannuario A,Rizzi A,Pieretti S,Guerrini R,Bertorelli R,Salvadori S,Regoli D,Calo G

更新日期：2001-12-04 00:00:00

abstract：:During hibernation the body temperature of the golden-mantled ground squirrel, Spermophilus lateralis, may drop below 5 degrees C for a few hours to a week or more. Animals cycle between euthermia and deep hibernation many times over the course of the hibernation season. Expression of the transcription factor c-fos in...

journal_title：Neuroscience letters

authors： Bitting L,Sutin EL,Watson FL,Leard LE,O'Hara BF,Heller HC,Kilduff TS

更新日期：1994-01-03 00:00:00

abstract：:After systemic administration of the dopamine agonist apomorphine (APO) in common toads Bufo bufo spinosus, the excitatory receptive fields of retinal R2 and R3 ganglion cells doubled their size and the response activities of these neurons to moving visual stimuli were generally increased. Comparable investigations of...

journal_title：Neuroscience letters

authors： Glagow M,Ewert JP

更新日期：1994-05-23 00:00:00

abstract：:Electrical stimulation (20-35 Hz, 2-5 V, 1.5 h) of the pelvic nerve in urethane-anesthetized rats increased the expression of c-fos protein-immunoreactivity primarily in neurons in the L6-S1 segments of the spinal cord. The neurons were localized to areas receiving afferent input from the pelvic viscera including the ...

journal_title：Neuroscience letters

authors： Birder LA,Roppolo JR,Iadarola MJ,de Groat WC

更新日期：1991-08-19 00:00:00

abstract：:Depressive disorders represent a significant health concern as they are associated with high social and physical dysfunction and increased risk for suicide. Electroconvulsive therapy (ECT) is the most effective treatment for patients with drug-resistant severe depressive disorders. However, the underlying biological m...

journal_title：Neuroscience letters

authors： Fryland T,Elfving B,Christensen JH,Mors O,Wegener G,Børglum AD

更新日期：2012-05-10 00:00:00

abstract：:Radiofrequency lesions of the ventral mesencephalic tegmentum (VMT), a region located above the nucleus interpeduncularis, provoked a disappearance of the spontaneous alternation behavior. The lesioned rats scores (44%) are not different from the chance level, while the alternation rate amounts to 77% in the control g...

journal_title：Neuroscience letters

authors： Galey D,Jaffard R,Le Moal M

更新日期：1976-09-01 00:00:00

abstract：:Activation of central neuropeptide Y (NPY) receptors is known to produce several behavioral effects, including feeding, modulation of memory and antagonism of behavioral effects of stress. In addition, experiments in knock-out and transgenic mice have suggested a possible role of NPY regulation of voluntary ethanol in...

journal_title：Neuroscience letters

authors： Thorsell A,Rimondini R,Heilig M

更新日期：2002-10-25 00:00:00

abstract：:The effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat were investigated. A plantar analgesic meter was used to measure carrageenan-induced changes in paw withdrawal latency (PWL) values, and von Frey monofilaments were used to assess changes in paw withdrawal thresh...

journal_title：Neuroscience letters

authors： Tall JM,Crisp T

更新日期：2004-01-16 00:00:00

abstract：:Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...

journal_title：Neuroscience letters

authors： Sun J,Ling Z,Wang F,Chen W,Li H,Jin J,Zhang H,Pang M,Yu J,Liu J

更新日期：2016-02-02 00:00:00

abstract：:The brain is the exclusive or almost exclusive site of formation of 24S-hydroxycholesterol and we have shown that the circulating level of 24S-hydroxycholesterol is dependent upon the relation between cerebral production and hepatic clearance. In the present work we determined plasma levels of 24S-hydroxycholesterol i...

journal_title：Neuroscience letters

authors： Bretillon L,Sidén A,Wahlund LO,Lütjohann D,Minthon L,Crisby M,Hillert J,Groth CG,Diczfalusy U,Björkhem I

更新日期：2000-10-27 00:00:00

abstract：:Rat neocortical slices maintained in Mg2(+)-free Krebs medium developed spontaneous paroxysmal discharges which were attenuated or suppressed by the gamma-aminobutyric acid-B (GABAB) receptor agonist baclofen, occasionally accompanied by a slight hyperpolarisation, and antagonised by the specific GABAB-receptor antago...

journal_title：Neuroscience letters

authors： Ong J,Kerr DI,Johnston GA,Hall RG

更新日期：1990-02-05 00:00:00

abstract：:The analgesic effect of kappa partial agonist opioids (i.e. nalbuphine, pentazocine and butorphanol) is significantly greater in women. Recent evidence suggests that this sexual dimorphism may result from a naloxone-sensitive anti-analgesic effect that is activated along with, and summates with, the analgesic effect o...

journal_title：Neuroscience letters

authors： Gear RW,Gordon NC,Miaskowski C,Paul SM,Heller PH,Levine JD

更新日期：2003-11-06 00:00:00

abstract：:Older adults have difficulties in binding information in long-term memory (e.g. objects with colours). The effect of age on visual short-term memory (VSTM) binding is less well understood. Recent evidence has suggested that older adults' VSTM for colours bound to shapes or for locations bound in configural representat...

journal_title：Neuroscience letters

authors： Parra MA,Abrahams S,Logie RH,Sala SD

更新日期：2009-01-02 00:00:00

abstract：:The present study is designed to screen the effect of syringin, an active principle purified from the rhizome and root parts of Eleutherococcus senticosus (Araliaceae), on the plasma glucose and investigate the possible mechanisms. Plasma glucose decreased in a dose-dependent manner 60 min after intravenous injection ...

journal_title：Neuroscience letters

authors： Liu KY,Wu YC,Liu IM,Yu WC,Cheng JT

更新日期：2008-03-28 00:00:00

abstract：:This study investigated the effects of mobile-phone-type radiation on the cerebral activity of seizure-prone animals. When rats transformed into an experimental model of seizure-proneness by acute subconvulsive doses of picrotoxin were exposed to 2 h GSM-modulated 900 MHz radiation at an intensity similar to that emit...

journal_title：Neuroscience letters

authors： López-Martín E,Relova-Quinteiro JL,Gallego-Gómez R,Peleteiro-Fernández M,Jorge-Barreiro FJ,Ares-Pena FJ

更新日期：2006-05-01 00:00:00

abstract：:We analyzed the participation of N-methyl-d-aspartate (NMDA) receptors in the neuronal damage caused by adult-onset hypothyroidism. Wistar rats were randomly assigned into four groups. The euthyroid group received tap water. The hypothyroid group received methimazole (60 mg/kg) in their drinking water to induce hypoth...

journal_title：Neuroscience letters

authors： Alva-Sánchez C,Becerril A,Anguiano B,Aceves C,Pacheco-Rosado J

更新日期：2009-04-10 00:00:00

abstract：:gamma-Aminobutyric acid (GABA)-mediated neurotransmission from the granule cells to CA3 is transiently expressed during the first 3 weeks of age in the rat. In the adult, seizures provoke this inhibitory signaling to reappear. To gain insight into the origin of GABA in these cells, we explored the expression of both i...

journal_title：Neuroscience letters

authors： Maqueda J,Ramírez M,Lamas M,Gutiérrez R

更新日期：2003-12-15 00:00:00

abstract：:In the present study, the effects of fluvoxamine on the inhibition of gastrointestinal transit, antinociception and hyperlocomotion induced by morphine were investigated in mice. Treatment with morphine (10 mg/kg, subcutaneously (s.c.)) inhibited gastrointestinal transit and hyperlocomotion. These effects were attenua...

journal_title：Neuroscience letters

authors： Ise Y,Katayama S,Hirano M,Aoki T,Narita M,Suzuki T

更新日期：2001-02-16 00:00:00

abstract：:Hydrogen peroxide (H(2)O(2)) is a major reactive oxygen species that has been implicated in various neurodegenerative diseases. Quercetin, one of the plant flavonoids, has been reported to harbor various physiological properties including antioxidant activity. In this study, we investigated the neuroprotective effects...

journal_title：Neuroscience letters

authors： Suematsu N,Hosoda M,Fujimori K

更新日期：2011-10-31 00:00:00

abstract：:The extracellular homeostasis of glutamate in the brain is maintained by the efficient uptake into astroglial cells. The high extracellular glutamate levels seen during seizures are therefore probably a result of both an increased synaptic release and a deranged glutamate uptake. In this study we used immuno-blotting ...

journal_title：Neuroscience letters

authors： Samuelsson C,Kumlien E,Flink R,Lindholm D,Ronne-Engström E

更新日期：2000-08-11 00:00:00

abstract：:Familial Alzheimer's disease (AD) due to PSEN1 mutations provides an opportunity to examine AD biomarkers in persons in whom the diagnosis is certain. We describe a 55 year-old woman with clinically probable AD and a novel PSEN1 mutation who underwent genetic, clinical, biochemical and magnetic resonance and nuclear i...

journal_title：Neuroscience letters

authors： Ringman JM,Gylys KH,Medina LD,Fox M,Kepe V,Flores DL,Apostolova LG,Barrio JR,Small G,Silverman DH,Siu E,Cederbaum S,Hecimovic S,Malnar M,Chakraverty S,Goate AM,Bird TD,Leverenz JB

更新日期：2011-01-10 00:00:00

abstract：:Numerous studies have provided evidence for a genetic association of the Apolipoprotein E (ApoE) epsilon4 allele and late onset familial and sporadic Alzheimer's disease (AD). Clinical observations show that a proportion of schizophrenic patients may suffer from severe cognitive impairment. That could reflect a partic...

journal_title：Neuroscience letters

authors： Sorbi S,Nacmias B,Tedde A,Latorraca S,Forleo P,Guarnieri BM,Petruzzi C,Daneluzzo E,Ortenzi L,Piacentini S,Amaducci L

更新日期：1998-03-13 00:00:00

abstract：:Within the normal inner ear, there are elements that belong to the immune system. Different inner ear disorders can be explained by autoimmune mechanisms, affecting both humoral and cellular immunity. Melatonin, the principal hormone of the pineal gland, modulates the immune system and extensively participates in the ...

journal_title：Neuroscience letters

authors： Lopez-Gonzalez MA,Guerrero JM,Delgado F

更新日期：1997-11-28 00:00:00

abstract：:We examined whether the mGluR1 and mGluR5 were involved in development and maintenance of behavioral signs of non-evoked pain and secondary mechanical hyperalgesia induced by knee joint inflammation. Selective mGluR1 antagonist, (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA: 50, 100, 200 microM/25 microl, n=10 per gro...

journal_title：Neuroscience letters

authors： Lee KS,Kim J,Yoon YW,Lee MG,Hong SK,Han HC

更新日期：2007-04-12 00:00:00

abstract：:Mice exposed to intermittent cold stress (ICS), but not constant cold stress (CCS) showed sustained thermal hyperalgesia for up to 12 days. Systemic or intracerebroventricular (i.c.v.) injection of morphine caused no significant analgesia in ICS mice, but induced dose-dependent analgesia in control mice. However, sign...

journal_title：Neuroscience letters

authors： Nishiyori M,Nagai J,Nakazawa T,Ueda H

更新日期：2010-03-26 00:00:00

abstract：:The ability of three nitric oxide (NO) donor compounds to modify ligand binding to kainate receptors was studied in tissue from human adult autopsy brains. Binding of [3H]kainic acid (5 nM) was measured in frontal cortex membranes made from Brodmann area 8 (BA 8) and autoradiographically using sections of frontal cort...

journal_title：Neuroscience letters

authors： Lees RD,Slater P,D'Souza SW

更新日期：1997-09-19 00:00:00

abstract：:In vitro studies suggest that insulin-like growth factor (IGF)-I is a mitogen for microglia/macrophages. The actions of IGF-I are mediated by IGF-I receptors and modulated by IGF binding proteins (IGFBPs). The aim of this study was to investigate IGF-I receptors and IGFBPs in human microglia in normal brain white matt...

journal_title：Neuroscience letters

authors： Chesik D,De Keyser J,Wilczak N

更新日期：2004-05-13 00:00:00