Supraspinal influences on the facilitation of rat nociceptive reflexes induced by carrageenan monoarthritis.

abstract：:The prenatal development of axonal connections in the rat olfactory system was studied using DiI. On day 16 (E16), the olfactory and vomeronasal nerves extended from the olfactory epithelia to the olfactory bulb (OB), the terminal nerve to the telencephalic septum, while axons of mitral and tufted cells reached the an...

journal_title：Neuroscience letters

authors： Marchand R,Bélanger MC

更新日期：1991-08-19 00:00:00

abstract：:Daily administration of clonidine for 5 weeks (approx. 300 micrograms/kg/day, p.o.) produced significant decreases in blood pressure and renal sympathetic efferent activity in spontaneously hypertensive rats (SHR). After cessation of clonidine administration, blood pressure and sympathetic nerve activity recovered rap...

journal_title：Neuroscience letters

authors： Yomaida I,Murao M,Togashi H,Shimamura K,Koike Y,Monma Y,Saito HA

更新日期：1979-12-01 00:00:00

abstract：:It is well established that the reinforcing effect of drugs of abuse is linked to the mesolimbic dopamine (DA) system. Morphine produces an increase in DA release in the brain, which may provide positive reinforcement contributing to the development of motivational aspects of drug-seeking and maintenance behavior. Sev...

journal_title：Neuroscience letters

authors： Yoon SS,Lee BH,Kim HS,Choi KH,Yun J,Jang EY,Shim I,Kim JA,Kim MR,Yang CH

更新日期：2007-11-20 00:00:00

abstract：:We have used light microscopic autoradiography to localize differentially Type 1 and 2 benzodiazepine receptors using pharmacologic and detergent treatment techniques. The triazolopyridazine CL218872 has preferential affinity for Type 1 receptors from which it displaces [3H]flunitrazepam selectivity. In biochemical ex...

journal_title：Neuroscience letters

authors： Lo MM,Niehoff DL,Kuhar MJ,Snyder SH

更新日期：1983-08-19 00:00:00

abstract：:A major action of adenosine is the induction of profound behavioral inactivity. 6-(4-Nitrobenzyl)-thioinosine (NBI) and 6-(2-hydroxy-5-nitrobenzyl)-thioguanosine (NBG) have been shown to inhibit adenosine uptake. To investigate the possible synergism between exogenous ligand and reuptake inhibition, mice were treated ...

journal_title：Neuroscience letters

authors： Crawley JN,Patel J,Marangos PJ

更新日期：1983-04-11 00:00:00

abstract：:We examined whether the mGluR1 and mGluR5 were involved in development and maintenance of behavioral signs of non-evoked pain and secondary mechanical hyperalgesia induced by knee joint inflammation. Selective mGluR1 antagonist, (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA: 50, 100, 200 microM/25 microl, n=10 per gro...

journal_title：Neuroscience letters

authors： Lee KS,Kim J,Yoon YW,Lee MG,Hong SK,Han HC

更新日期：2007-04-12 00:00:00

abstract：BACKGROUND:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a subcortical, inherited, cerebral small vessel disease. Several studies have revealed the involvement of specific cortical regions. However, the structural brain alterations and their clinical correlation...

journal_title：Neuroscience letters

authors： Pan H,Huang Q,Ban S,Du X,Su J,Liu J

更新日期：2020-11-01 00:00:00

abstract：:Various tracer substances were injected into the spinal cord, the dorsal column nuclei, the trigeminal nuclear complex and the somatosensory cortex in Madagascan hedgehog tenrecs. With the exception of the cases injected exclusively into the spinal cord all injections gave rise to sparse, but distinct anterograde proj...

journal_title：Neuroscience letters

authors： Wolff A,Künzle H

更新日期：1997-01-17 00:00:00

abstract：:In the present study we have investigated the effects of nicotine, capsaicin, potassium, glutamate and aspartate on release of calcitonin gene-related peptide (CGRP)-like immunoreactivity (-LI) from guinea-pig dorsal root ganglion (DRG) cultures. In addition the possible influence of Ruthenium red (RR), neuropeptide Y...

journal_title：Neuroscience letters

authors： Franco-Cereceda A,Rydh M,Dalsgaard CJ

更新日期：1992-03-16 00:00:00

abstract：:In the present study, tyrosine hydroxylase (TH; EC 1.14.16.2) cDNA was transfected into cultured fibroblasts and the production of L-3,4-dihydroxyphenylalanine (L-DOPA) was determined. Type 2 TH cDNA was transfected into fibroblasts (NRK-49F) derived from the normal rat kidney, and the expression of the TH minigene wa...

journal_title：Neuroscience letters

authors： Uchida K,Ishii A,Kaneda N,Toya S,Nagatsu T,Kohsaka S

更新日期：1990-02-16 00:00:00

abstract：:Parkinson's disease (PD) is one of the common neurodegenerative diseases that result in the progressive damage of dopaminergic neurons. Environmental exposure, including paraquat, is considered risky for PD. Epigenetics refer to the study of heritable changes in gene expression that occur without a change in DNA seque...

journal_title：Neuroscience letters

authors： Kong M,Ba M,Liang H,Ma L,Yu Q,Yu T,Wang Y

更新日期：2012-08-22 00:00:00

abstract：:We investigated the origin of alpha-synuclein-immunoreactive components in Lewy bodies (LB) in brains of dementia with Lewy bodies (DLB) using immunohistochemistry and immunoelectron microscopy with anti-alpha-synuclein antibodies and anti-cytoskeleton antibodies. alpha-Synuclein-positive LB light microscopically cons...

journal_title：Neuroscience letters

authors： Iseki E,Marui W,Sawada H,Uéda K,Kosaka K

更新日期：2000-08-18 00:00:00

abstract：:Since greater attention has been paid to the direct link of genetic variation to cognition and memory performance, apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) have been the two most frequently studied genes. To investigate the effect of BDNF and ApoE polymorphisms on the cognitive profile of m...

journal_title：Neuroscience letters

authors： Nacmias B,Piccini C,Bagnoli S,Tedde A,Cellini E,Bracco L,Sorbi S

更新日期：2004-09-09 00:00:00

abstract：:The dentate gyrus of the hippocampus is one of few regions in the adult mammalian brain characterized by ongoing neurogenesis. It has been demonstrated that Noggin antagonizes bone morphogenetic protein-4 (BMP4) to create a niche for subventricular zone neurogenesis. We previously demonstrated that Noggin and BMP4 sho...

journal_title：Neuroscience letters

authors： Fan XT,Xu HW,Cai WQ,Yang H,Liu S

更新日期：2004-08-05 00:00:00

abstract：:The effect of nitric oxide donor compounds (sodium nitroprusside, hydroxylamine and S-nitroso-N-acetyl-D,L-penicillamine) on depolarization-induced release of endogenous dopamine in the light-adapted, isolated retina of the rabbit was studied by HPLC. All three compounds had the same effect, reducing the amount of dop...

journal_title：Neuroscience letters

authors： Djamgoz MB,Cunningham JR,Davenport SL,Neal MJ

更新日期：1995-09-22 00:00:00

abstract：:The possibility that single electrical shock stimulation of somatic afferent nerves could evoke a reflex response in vagal efferent nerves innervating the stomach was examined using anesthetized, artificially-ventilated rats. A single shock to a hindlimb afferent nerve (tibial nerve) produced two distinct reflex compo...

journal_title：Neuroscience letters

authors： Kimura A,Sato A,Sato Y,Suzuki A

更新日期：1996-05-24 00:00:00

abstract：:Dietary flavonoids, including the citrus flavanone hesperetin, may have stimulatory effects on cytoprotective intracellular signalling pathways. In primary mouse cortical neurone cultures, but not SH-SY5Y human neuroblastoma cells or human primary dermal fibroblasts (Promocells), hesperetin (100-300nM, 15min) caused s...

journal_title：Neuroscience letters

authors： Rainey-Smith S,Schroetke LW,Bahia P,Fahmi A,Skilton R,Spencer JP,Rice-Evans C,Rattray M,Williams RJ

更新日期：2008-06-13 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP22) gene which results in an abnormal myelination of its peripheral nervous system. The recent identification of two different PMP22 mRNA differing in their 5' non-translated region led us to monitor their respectiv...

journal_title：Neuroscience letters

authors： Garbay B,Boiron-Sargueil F,Cassagne C

更新日期：1995-10-06 00:00:00

abstract：:Radiofrequency lesions of the ventral mesencephalic tegmentum (VMT), a region located above the nucleus interpeduncularis, provoked a disappearance of the spontaneous alternation behavior. The lesioned rats scores (44%) are not different from the chance level, while the alternation rate amounts to 77% in the control g...

journal_title：Neuroscience letters

authors： Galey D,Jaffard R,Le Moal M

更新日期：1976-09-01 00:00:00

abstract：:Tritiated dipyridamole, a specific adenosine uptake inhibitor binds in a saturable and reversible fashion to high-affinity receptor sites in guinea pig brain sections (Kd = 10 +/- 1.5 nM; Bmax = 650 +/- 100 fmol/mg prot.). The anatomical distribution of [3H]dipyridamole binding sites obtained with autoradiographic tec...

journal_title：Neuroscience letters

authors： Bisserbe JC,Deckert J,Marangos P

更新日期：1986-05-23 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by amyloid plaques, neuritic degenerations, disturbed glutamatergic neurotransmission and a peculiar inflammatory response. Diffuse plaques develop into neuritic plaques when neurites undergo degeneration in the plaque area. Hyperphosphorylation of tau proteins is a major step...

journal_title：Neuroscience letters

authors： Hüll M,Eistetter J,Fiebich BL,Bauer J

更新日期：1999-02-12 00:00:00

abstract：:Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. ch...

journal_title：Neuroscience letters

authors： Park SY,Park SJ,Park NJ,Joo WH,Lee SJ,Choi YW

更新日期：2013-10-25 00:00:00

abstract：:Reflex responses of adrenal sympathetic nerve activity to stimulation of baroreceptor and cutaneous mechanoreceptors were compared in young adult (4 months old) and aged (26 months old) rats, under strictly controlled conditions for anesthesia, respiration and body temperature. Under these conditions the reflex depres...

journal_title：Neuroscience letters

authors： Kurosawa M,Sato A,Sato Y,Suzuki H

更新日期：1987-06-15 00:00:00

abstract：:Injection of the triceps brachii muscle of the rat with horseradish peroxidase (HRP) led to labeling of motoneurons in the dorsolateral and ventral aspects of the ventral grey horn of the brachial spinal cord. Ventral, labeled neurons were absent, however, in rats in which the motor branches of the radial nerve to tri...

journal_title：Neuroscience letters

authors： Haase P,Hrycyshyn AW

更新日期：1985-10-10 00:00:00

abstract：:The olfactory system plays an important role in both animal and human anxiety reactions. However, results on olfactory performance during the course of clinical anxiety disorders remain scarce. Therefore, we conducted an exploratory pilot study in 17 patients currently diagnosed with an anxiety disorder. Patients part...

journal_title：Neuroscience letters

authors： Clepce M,Reich K,Gossler A,Kornhuber J,Thuerauf N

更新日期：2012-03-05 00:00:00

abstract：:As the pre-dementia phase of Alzheimer disease, mild cognitive impairment (MCI) involves the onset and development of cognitive impairments. Opioid receptors play pivotal roles in the regulation of learning and cognition. Our study focused on the association of OPRK1 and OPRM1 methylation with MCI in Xinjiang Uygur an...

journal_title：Neuroscience letters

authors： Liu G,Ji H,Liu J,Xu C,Chang L,Cui W,Ye C,Hu H,Chen Y,Zhou X,Duan S,Wang Q

更新日期：2017-01-01 00:00:00

abstract：:Age-related impairment of learning and memory is a common phenomenon in humans and animals, yet the underlying mechanism remains unclear. We hypothesize that a small ubiquitin-related modifier (Sumo) might correlate with age-related loss of learning and memory. To test this hypothesis, the present study evaluated age-...

journal_title：Neuroscience letters

authors： Yang QG,Wang F,Zhang Q,Xu WR,Chen YP,Chen GH

更新日期：2012-06-19 00:00:00

abstract：:Application of a GABAA (gamma-aminobutyric acid-A) receptor antagonist through a microdialysis probe into the forelimb primary motor cortex of ketamine-anesthetized rats induced electromyographic activity in the contralateral forelimb. This activity consisted of spontaneous forelimb movements with a frequency of 0.8 +...

journal_title：Neuroscience letters

authors： Castro-Alamancos MA,Borrell J

更新日期：1993-02-19 00:00:00

abstract：:Physical exercise is beneficial to functional recovery after stroke. But its underling mechanism is still unknown. It is reported that neural stem cells (NSCs) proliferation, migration and differentiation play an important role in recovery following stroke, furthermore, stromal cell derived factor-1α (SDF-1α) and its ...

journal_title：Neuroscience letters

authors： Luo J,Hu X,Zhang L,Li L,Zheng H,Li M,Zhang Q

更新日期：2014-08-22 00:00:00

abstract：:Bone mesenchymal stem cells (BMSCs) are an attractive donor graft source because of the potential of self-renewal and multi-direction differentiation. However, it is a great challenge to induce BMSCs to specifically differentiate to dopamine (DA) neurons for the treatment of Parkinson's disease. Because the striatum i...

journal_title：Neuroscience letters

authors： Yang S,Gao Q,Bao L,Zhang J,Hu Y,Bing L,Sun J,Hao J,Chen C,Li S,Poon WS,Sun J,Gao Y

更新日期：2012-11-21 00:00:00