Abstract:
:During hyperalgesia there is an enhancement of wind-up and the appearance of a novel wind-up of the A-fibre-mediated responses. We have examined if these phenomena are influenced by supraspinal mechanisms by analysing single motor unit activity in control and arthritic rats, either intact or acutely spinalised. Enhancement of the C-fibre wind-up and the novel A-fibre wind-up were only observed in the intact arthritic animals. We conclude that C-fibre wind-up is a spinal phenomenon, whereas the enhancement of the C-fibre wind-up and the novel A-fibre wind-up during arthritis depend also on supraspinal influences.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Herrero JF,Cervero Fdoi
10.1016/0304-3940(96)12588-xsubject
Has Abstractpub_date
1996-05-03 00:00:00pages
21-4issue
1eissn
0304-3940issn
1872-7972pii
030439409612588Xjournal_volume
209pub_type
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