Abstract：
:Cuneo-thalamic projection cells in the rat were identified after injection of horseradish peroxidase into the contralateral thalamic nucleus ventralis posterolateralis. By light microscopy, labelled cells were 16-20 microm in diameter, round or oval in shape, distributed throughout the cuneate nucleus and concentrated in the region of the obex. By electron microscopy, reaction products were found in two different types of neuronal profile. Most were 16-19 microm in diameter, round or slightly oval, with a smooth nucleus, small stacks of rough endoplasmic reticulum and many axo-somatic synapses. The remaining profiles were oval, 14-19 microm in long diameter, with a flattened, indented nucleus and very few axo-somatic synapses.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Tan CK,Lieberman ARdoi
10.1016/0304-3940(78)90005-8subject
Has Abstractpub_date
1978-11-01 00:00:00pages
19-22issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(78)90005-8journal_volume
10pub_type
杂志文章abstract：:Parkinson's disease (PD) is a neurodegenerative disease and its prevalence increases with age. The microtubule-associated protein tau (MAPT) is thought to be implicated in the pathogenesis of PD. Association of the MAPT H1 haplotype with PD in Caucasians has been extensively studied, however, the results were inconsis...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.06.057
更新日期：2006-09-25 00:00:00
abstract：:The gamma aminobutyric acid (GABA) system has been implicated in the susceptibility to develop alcohol dependence and in determining electroencephalogram (EEG) beta activity. The role of the GABA receptor alpha-2 gene (GABRA2) in human alcohol dependence was determined in a genetic and electrophysiological study. The ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.05.240
更新日期：2011-08-18 00:00:00
abstract：:A previous study has shown that inflammation of the gastrocnemius-soleus muscle in rats leads to an increase in excitability of dorsal horn neurones particularly in the spinal segment L3. Here, we have blocked the nitric oxide synthase (NOS) in L3 by spinal cord superfusion with NG-monomethyl-L-arginine (L-NMMA) to fi...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(95)11411-o
更新日期：1995-03-24 00:00:00
abstract：:This study examines the ultrastructural relationships established by the nigrostriatal dopaminergic and the corticostriatal afferent fibers with neuropeptide Y (NPY)-containing neurons in the rat striatum. By means of dual immunolabeling procedures using peroxidase conjugated F(ab) fragments and 125I-labeled protein A...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(89)90667-8
更新日期：1989-05-22 00:00:00
abstract：:Parkinson disease (PD) features profound striatal dopamine depletion and Lewy bodies containing abundant precipitated alpha-synuclein. Mechanisms linking alpha-synucleinopathy with the death of dopamine neurons remain incompletely understood. One such link may be 3,4-dihydroxyphenylacetaldehyde (DOPAL). All of the int...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.03.016
更新日期：2014-05-21 00:00:00
abstract：:The present study examined the coordination dynamics of the head and center of mass (COM) using accelerometry in quiet 1 and 2 leg stance with and without vision. The root mean square jerk of effectors was greater in 1 leg stance and without vision, and was greater for the head in 2 leg stance and greater at the COM f...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.05.068
更新日期：2013-08-26 00:00:00
abstract：:Global cerebral ischemia-reperfusion (GCI/R) may occur after any of several clinical conditions such as cardiac arrest and anesthetic accident. Some dopamine receptor agonists possess neuroprotective effects. However, some of them may produce side effects during treatment. Piribedil, which is a dopamine D2/D3 receptor...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2018.08.011
更新日期：2018-09-25 00:00:00
abstract：:Transcranial pulsed current stimulation (tPCS) and transcranial direct current stimulation (tDCS) are two noninvasive neuromodulatory brain stimulation techniques whose effects on human brain and behavior have been studied individually. In the present study we aimed to quantify the effects of tDCS and tPCS, individual...
journal_title：Neuroscience letters
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.neulet.2016.10.026
更新日期：2017-01-10 00:00:00
abstract：:In the rat, electrical stimulation of the cranial end of the cut hepatic branch of the vagus nerve modulated gastric contractions. When the gastric contraction rate reached approximately one per min, nerve stimulation caused total suppression. When the stomach was free of contraction, nerve stimulation initiated one. ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(85)90097-7
更新日期：1985-01-07 00:00:00
abstract：:Electrophysiological and biochemical studies have indicated that GABAergic modulation is involved in the opioid-induced altering of response properties of visual cortical cells and impairing of short-term synaptic plasticity in the geniculo-cortical visual pathway. The aim of the current study was to examine whether t...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2007.09.041
更新日期：2007-11-20 00:00:00
abstract：:In rats anesthetized with pentobarbital or a mixture of urethane and chloralose, horseradish peroxidase (HRP) was injected into the intermediolateral column of the spinal cord (Th7 and Th9) or the posterior pituitary lobe. HRP positive cells were found mainly in the dorsomedial part of the paraventricular nuclease (PV...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(78)90025-3
更新日期：1978-11-01 00:00:00
abstract：:Previously published data have indicated that in the rat, unlike other species examined, the kidney is not supplied by sensory nerves containing substance P (SP). As part of a study of reflex control of renal function in the rat, we have now reassessed this situation. Many fine, varicose, SP-immunoreactive nerve fiber...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(85)90241-1
更新日期：1985-09-30 00:00:00
abstract：:In the present study, we demonstrate that the histopathologic features of myelin oligodendrocyte glycoprotein (MOG) peptide 35-55-induced experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice closely mirror the hallmarks of MS pathology. On the one hand, we depict a time-dependent transition from acute infla...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.03.021
更新日期：2011-05-02 00:00:00
abstract：:Pigment epithelium-derived factor (PEDF) is a potent and broadly acting neurotrophic factor that protects various cultured neurons against apoptotic stimuli. To investigate whether PEDF acts not only on neurons, but also glial cells, we analyzed the effects of recombinant human PEDF (rhPEDF) on cytokine mRNA levels, t...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.01.035
更新日期：2005-05-20 00:00:00
abstract：:Pharmacological blocking agents were used to assess the contributions of different K(+)-currents to spike-repolarization and early spike-afterhyperpolarization recorded in dissociated, tissue-cultured rat superior cervical sympathetic neurones using both patch-clamp and impalement microelectrode techniques. Effects of...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90593-i
更新日期：1991-12-09 00:00:00
abstract：:This study investigated the neuroprotective effects of COG1410, an apoliporotein E (apoE)-derived mimic peptide, against early brain injury (EBI) after subarachnoid hemorrhage (SAH). SAH was induced in C57BL/6J mice (n=68) by endovascular perforation. Mice received intravenous injection of COG1410 (2mg/kg) or equal vo...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2016.05.058
更新日期：2016-08-03 00:00:00
abstract：:In the rat, unilateral intrastriatal injection of monoclonal antibodies to acetylcholinesterase (AChE) produced ipsilateral disappearance of AChE-positive nerve terminals within striatum and adjacent cortex. No alterations in striatal staining patterns were observed for tyrosine hydroxylase, somatostatin, neuropeptide...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90078-8
更新日期：1991-11-25 00:00:00
abstract：:Carvedilol's potent antioxidant activity could explain its protective action in brain ischemia, but may not apply to glutamate-induced excitotoxicity in cultured cerebellar granule cells, since glutamate neurotoxicity was not associated with the formation of lipid peroxidative products. Rather, carvedilol diminished t...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(92)90798-c
更新日期：1992-12-14 00:00:00
abstract：:Dopamine metabolism and release were determined in the striata of rats sustaining varying damage to the nigrostriatal dopamine (DA) projection. DA metabolism, inferred from concentrations of dihydroxy-phenylacetic acid (DOPAC) or homovanillic acid (HVA), decreased with DA denervation of more than 20%. Dopamine release...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(89)90400-x
更新日期：1989-01-30 00:00:00
abstract：:The effects of the normotensive, mainly centrally active nitric oxide synthase (NOS) inhibitor 7-nitro indazole and the hypertensive drug NG-nitro-L-arginine, which blocks both the endothelial and the central NOS, have been examined on naloxone-precipitated withdrawal in morphine-dependent rats. Both drugs attenuated ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)11116-z
更新日期：1995-01-02 00:00:00
abstract：:Spatial memory is coordinated with different brain regions especially hippocampus (HIP) and medial prefrontal cortex (mPFC). Influence of noise stress on working and reference memory error in rats was evaluated by radial eight-arm maze experiment. Changes in the dendritic count were observed in the brain regions such ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.01.037
更新日期：2006-05-15 00:00:00
abstract：:Studies of cognitive behavior in rodent models of Alzheimer's disease (AD) are the mainstay of academic and industrial efforts to find effective treatments for this disorder. However, in the majority of such studies, the nature of rodent behavioral tests is considerably different from the setting associated with cogni...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2017.04.049
更新日期：2017-05-22 00:00:00
abstract：:The accumulation of choline acetyltransferase (CAT) proximal to and nerve growth factor (NGF) distal to the intraneural site of tetrodotoxin (TTX) or batrachotoxin (BTX) injection in vivo was used to monitor orthograde and retrograde axonal transport. Orthograde axonal transport was blocked by BTX for up to 7-10 days ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(80)90317-1
更新日期：1980-06-01 00:00:00
abstract：:On anesthetized adult rats, we examined the possibility that the discharges of spinocerebellar Purkinje cells (PCs) are modulated by passive limb positioning. The rat forelimb was passively placed in four different sagittal positions while the simple spike spontaneous activity of single PCs was recorded; recordings st...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00185-2
更新日期：1998-04-03 00:00:00
abstract：:Involvement of the ipsilateral hemisphere during planning of reaching movements is still matter of debate. While it has been demonstrated that the contralateral hemisphere is dominant in visuo-motor integration, involvement of the ipsilateral hemisphere has also been proposed. Furthermore, a dominant role for left pos...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.05.028
更新日期：2009-08-28 00:00:00
abstract：:Neuroglobin (Ngb) is a novel vertebrate globin expressed principally in neurons. Ngb expression is induced by hypoxia and ischemia, and Ngb protects neurons against these insults. The mechanism of Ngb's protective action is unknown, but its ability to bind NO suggests that NO scavenging might be involved. To test this...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2007.10.031
更新日期：2008-01-10 00:00:00
abstract：:In vitro pituitary adenylate cyclase activating polypeptide (PACAP) induces the expression of brain-derived neurotrophic factor (BDNF) via its specific receptor PAC1. Since BDNF has been implicated in learning paradigms and mice lacking functional PAC1 have deficits in hippocampus-dependent associative learning, we in...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.01.030
更新日期：2004-04-22 00:00:00
abstract：:Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in children and adolescents and both environmental and genetic factors play major roles. Polyunsaturated fatty acids (PUFAs) are postulated to contribute to the development of the infant brain and an imbalance in these may increase the risk of ADHD. I...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.11.023
更新日期：2014-01-24 00:00:00
abstract：:Using functional near-infrared spectroscopy (fNIRS) we recorded prefrontal cortex (PFC) activation during positive, negative and neutral film clips, based on affective ratings according to their valence and arousal, to assess gender differences in cerebral activation in 15 male and 15 female volunteers. To record PFC ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.04.050
更新日期：2006-07-31 00:00:00
abstract：:Nuclear factor kappa B (NF(kappa)B) transcription factor plays a key role in the expression of many genes involved in the inflammatory process. We used the Freund's Complete Adjuvant (FCA)-induced model of peripheral inflammation to investigate the anti-inflammatory effects of double stranded oligodeoxynucleotides (OD...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.02.020
更新日期：2005-06-10 00:00:00
