Abstract:
:Bilateral complete transection of the fimbria-fornix causes a significant increase in nerve growth factor (NGF) content both in the septum and hippocampus of the adult rat as measured by a sensitive immunoassay 7 days after lesioning. The finding, that elevation of NGF in septum (250%) was much more pronounced than that in the hippocampus (30-50%), cannot be explained by retrograde axonal transport. Degeneration of central cholinergic neurons might be a potential trigger for NGF production in the CNS.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Weskamp G,Gasser UE,Dravid AR,Otten Udoi
10.1016/0304-3940(86)90449-0subject
Has Abstractpub_date
1986-09-25 00:00:00pages
121-6issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(86)90449-0journal_volume
70pub_type
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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