Hypothalamic neurons projecting to the rat caudal medulla oblongata, examined by immunoperoxidase staining of retrogradely transported horseradish peroxidase.

Abstract:

:Horseradish peroxidase (HRP), injected into the rat caudal medulla oblongata, was detected by immunoperoxidase staining in 120 microns frozen sections, allowing examination of both the distribution and morphology of transporting neurons. In the hypothalamus, several groups of HRP-labeled neurons could be distinguished on the basis of location of the neurons, neural cell size and morphology of the neural processes. Most HRP-labeled neurons were found in the posterior half of the hypothalamus, although scattered single neurons were present as far rostral as the anterior hypothalamus and preoptic area. Prominent groups of HRP-labeled neurons were found in the paraventricular, dorsomedial and arcuate nuclei, near the fornix at two separate levels, and in the lateral posterior hypothalamus. Based on comparison with peptide immunohistochemistry it seems likely that many magnocellular oxytocin, vasopressin and neurophysin neurons in the paraventricular nucleus, and a few ACTH/beta-endorphin neurons in the arcuate nucleus may project to the caudal medulla oblongata.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Sofroniew MV,Schrell U

doi

10.1016/0304-3940(80)90270-0

subject

Has Abstract

pub_date

1980-10-02 00:00:00

pages

257-63

issue

3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(80)90270-0

journal_volume

19

pub_type

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