Sleep-associated variations in plasma renin activity and blood pressure in the rat.

abstract：:Spasticity in chronic hemiparetic stroke patients has primarily been treated pharmacologically. However, there is increasing evidence that physical rehabilitation can help manage hyper-excitability of reflexes (hyperreflexia), which is a primary contributor to spasticity. In the present study, one chronic hemiparetic ...

journal_title：Neuroscience letters

authors： Hoseini N,Koceja DM,Riley ZA

更新日期：2011-10-24 00:00:00

abstract：:The input-output relation of a single neuron stands at the basis of every biologically oriented description of the brain. This report shows that the input-output relation of cultured cortical neurons is non-linearly tuned by the input frequency. Increasing the rate of stimulation results in the appearance of ordered t...

journal_title：Neuroscience letters

authors： Tal D,Jacobson E,Lyakhov V,Marom S

更新日期：2001-03-02 00:00:00

abstract：:Nerve fibers immunoreactive for vasoactive intestinal polypeptide (VIP) were demonstrated by immunocytochemistry in the dog and rat kidney. They were seen in association with the renal artery and its branches. In the dog, VIP-immunoreactive fibers were rarely seen close to small blood vessels suggestive of arterioles....

journal_title：Neuroscience letters

authors： Barajas L,Sokolski KN,Lechago J

更新日期：1983-12-30 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease characterized pathologically by the selective loss of dopaminergic neurons in the substantia nigra and the intracellular accumulation of α-synuclein in the Lewy bodies. While the pathogenic mechanisms of PD are poorly understood, many lines of evidence poi...

journal_title：Neuroscience letters

authors： Sheehan P,Yue Z

更新日期：2019-04-01 00:00:00

abstract：:The magnetic cell sorter (MACS) technique was applied to isolate retinal ganglion cells (RGCs) for culture. RGCs were labeled retrogradely with 1.1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (Dil). Subsequently retinal cell suspensions were incubated with biotinylated anti-rat Thy-1 antibody and MA...

journal_title：Neuroscience letters

authors： Shoge K,Mishima HK,Mukai S,Shinya M,Ishihara K,Kanno M,Sasa M

更新日期：1999-01-08 00:00:00

abstract：:In urethane-chloralose anesthetized rats, the role of GABA(B) receptor in the commissural subnucleus of the nucleus tractus solitarii (commNTS) on the carotid chemoreceptor reflex was investigated. Microinjection of a GABA(B) agonist baclofen into the commNTS did not have any effects on arterial blood pressure (BP) or...

journal_title：Neuroscience letters

authors： Suzuki M,Tetsuka M,Endo M

更新日期：1999-01-22 00:00:00

abstract：:Carvedilol's potent antioxidant activity could explain its protective action in brain ischemia, but may not apply to glutamate-induced excitotoxicity in cultured cerebellar granule cells, since glutamate neurotoxicity was not associated with the formation of lipid peroxidative products. Rather, carvedilol diminished t...

journal_title：Neuroscience letters

authors： Lysko PG,Lysko KA,Webb CL,Feuerstein G

更新日期：1992-12-14 00:00:00

abstract：:Whole-cell and single channel recordings were used to characterize an intermediate conductance calcium-activated potassium (KCa) channel in sensory neurons of the nodose ganglion. From a -80 mV holding potential, the total outward current in these neurons was increased when extracellular calcium was raised from 0.02 t...

journal_title：Neuroscience letters

authors： Hay M,Kunze DL

更新日期：1994-02-14 00:00:00

abstract：:Freshwater clams are a popular health food in Asia and are traditionally used to prevent hepatic inflammation. Freshwater clam extract (FCE) inhibits inflammatory responses in activated macrophages by reducing the activation of mitogen-activated protein kinase and nuclear factor kappa-light-chain-enhancer of activated...

journal_title：Neuroscience letters

authors： Hsieh CC,Lin MS,Hua KF,Chen WJ,Lin CC

更新日期：2017-03-06 00:00:00

abstract：:Changes in extracellular Ca2+ concentration ([Ca2+]e) evoked by transmitters and transmitter agonists, respectively, and by elevation of bath K+ concentration were recorded in isolated segmental ganglia of the leech Hirudo medicinalis using Ca(2+)-selective microelectrodes. A 1-min bath application of kainate (10 micr...

journal_title：Neuroscience letters

authors： Lohr C,Rose CR,Deitmer JW

更新日期：1996-02-16 00:00:00

abstract：:The number of granule cell dendritic spines per micrometer of dendritic length in the dorsal and ventral leaves of the dentate gyrus was quantified using light microscopic-Golgi preparations of normal adult rats. Spines were counted in terms of 3 categories of spine form for the 3 afferent termination zones of the mol...

journal_title：Neuroscience letters

authors： Desmond NL,Levy WB

更新日期：1985-03-15 00:00:00

abstract：:Noradrenergic fibers from the locus ceruleus were identified in close proximity to brain microvessels, and adrenoceptors exist in isolated brain capillaries. Yet, proof of innervation of brain microvessels by locus ceruleus remains elusive. We now demonstrate increased density of beta-adrenoceptors by pindolol binding...

journal_title：Neuroscience letters

authors： Kalaria RN,Stockmeier CA,Harik SI

更新日期：1989-02-13 00:00:00

abstract：:The insular cortex (IC) processes multimodal sensory information including gustatory, visceral, nociceptive, and thermal sensation, and is considered to play a role in the regulation of homeostasis. The IC receives dense histaminergic projection from the tuberomamillary nucleus in the hypothalamus, and recent studies ...

journal_title：Neuroscience letters

authors： Takei H,Song L,Ebihara K,Shirakawa T,Koshikawa N,Kobayashi M

更新日期：2012-06-14 00:00:00

abstract：:We investigated corticospinal excitability during positive (execution) and negative (suppression) imageries for the right and left upper and lower limbs. In the Positive Imagery tasks, sixteen subjects were instructed to repeatedly imagine rotation of the index finger of the right or left hand, or the ankle of the rig...

journal_title：Neuroscience letters

authors： Yokota H,Mizuguchi N,Kakigi R,Nakata H

更新日期：2018-04-13 00:00:00

abstract：:Angiotensin II-sensitive neurons in the brain of spontaneously hypertensive rats (SHR-sp) and of Wistar Kyoto rats (WKY) treated with the angiotensin-converting enzyme inhibitor Captopril were investigated for possible differences at receptor sites. Furthermore, the concentrations of angiotensinogen and renin were mea...

journal_title：Neuroscience letters

authors： Felix D,Schelling P

更新日期：1982-12-23 00:00:00

abstract：:Experiments using functional magnetic resonance imaging (fMRI) play a fundamental role in affective neuroscience. When placed in an MR scanner, some volunteers feel safe and relaxed in this situation, while others experience uneasiness and fear. Little is known about the basis and consequences of such inter-individual...

journal_title：Neuroscience letters

authors： Mutschler I,Wieckhorst B,Meyer AH,Schweizer T,Klarhöfer M,Wilhelm FH,Seifritz E,Ball T

更新日期：2014-11-07 00:00:00

abstract：:Light microscopic immunohistochemistry was used to investigate the presence and distribution of chromogranin A-like immunoreactivity in the human anal canal. In the anal transitional zone (ATZ), anal duct and anal gland epithelium, a varied number of mostly elongated cells strongly stained for CGA, using an antibody d...

journal_title：Neuroscience letters

authors： Weihe E,Hörsch D,Eiden LE,Hartschuh W

更新日期：1991-09-16 00:00:00

abstract：:1-methyl-4-phenylpyridinium ion (MPP(+)) has been shown to selectively inhibit mitochondrial function and induce a parkinsonism-like syndrome. MPP(+) stimulates the production of reactive oxygen species (ROS) and induces cell death in vitro. In this study, we investigated the protective effects of okadaic acid on MPP(...

journal_title：Neuroscience letters

authors： Ahn KH,Kim YS,Kim SY,Huh Y,Park C,Jeong JW

更新日期：2009-01-09 00:00:00

abstract：:Using the gerbil model of post-ischemic neuron death in the hippocampal CA1 region, it was recently shown that there is a strong down-regulation of voltage-gated Ca2+ influx in neurons examined at 2 days after the ischemic insult (Connor, J.A., Razani-Boroujerdi, S., Greenwood, A.C., Cormier, R.J., Petrozzino, J.J. an...

journal_title：Neuroscience letters

authors： Shuttleworth CW,Greenwood AC,Connor JA

更新日期：2000-06-02 00:00:00

abstract：:In the brains of male zebra finches (Taeniopygia guttata), the nuclei that direct song learning and production are larger than the corresponding regions in females, who do not sing. The dimorphism in Area X of the medial striatum (MSt), an area important for song learning, is even more dramatic in that it is identifia...

journal_title：Neuroscience letters

authors： Bailey DJ,Wade J

更新日期：2006-06-19 00:00:00

abstract：:Presenilin-1 (PSEN1) mutations I143T and G384A give rise to severe early onset Alzheimers's disease in two extensively studied Belgian families, AD/A and AD/B. In this study we investigated the influence of the I143T and G384A mutations on PSEN1 proteolytic processing. Hereto we analyzed PSEN1 processing in lymphoblas...

journal_title：Neuroscience letters

authors： Vanderhoeven I,Cras P,Martin JJ,Van Broeckhoven C,De Jonghe C

更新日期：1999-10-29 00:00:00

abstract：:Recombinant gamma-aminobutyric acid (GABA(A)) receptor channels containing alpha1beta2gamma2-subunits were transiently expressed in HEK293 cells. Modulation by diazepam (DZ) was investigated using the patch-clamp technique with a device for ultra-fast solution exchange. GABA activated Cl(-)-currents were potentiated w...

journal_title：Neuroscience letters

authors： Krampfl K,Lepier A,Jahn K,Franke C,Bufler J

更新日期：1998-11-13 00:00:00

abstract：:The displaced retinal ganglion cells in normal rats and rats with left eye enucleated at birth were studied using the fluorescent dye Fast blue as neuronal marker. The dye was introduced to the right optic tract of the rats 7 days before perfusion. Frozen coronal sections of the brains and retinal whole-mounts from al...

journal_title：Neuroscience letters

authors： Liu ZH,Jen LS

更新日期：1986-06-30 00:00:00

abstract：:The present study was designed to observe the effect of orphanin FQ (OFQ, also known as 'nociceptin'), a newly-discovered neuropeptide, on pain behavior and morphine analgesia evaluated by formalin test in rats. It was found that intracerebroventricular (i.c.v.) injection of 0.1 microg OFQ had no effect on formalin-in...

journal_title：Neuroscience letters

authors： Zhu CB,Cao XD,Xu SF,Wu GC

更新日期：1997-10-10 00:00:00

abstract：:Intrinsically bursting (IB) neurons, responding with a burst of action potentials to just threshold intracellular depolarizing current pulses, are encountered in layer V of mature rodent sensorimotor cortex. We report the results of intracellular recordings performed on neocortical slices obtained from immature rats b...

journal_title：Neuroscience letters

authors： Franceschetti S,Buzio S,Sancini G,Panzica F,Avanzini G

更新日期：1993-11-12 00:00:00

abstract：:Methylated beta-carboline compounds are mammalian indole metabolites that we have proposed to be endogenous neurotoxins due to their structural similarity to MPP+, the active oxidized product of the dopaminergic toxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Several laboratories have demonstrated that MPP...

journal_title：Neuroscience letters

authors： Neafsey EJ,Drucker G,Raikoff K,Collins MA

更新日期：1989-11-06 00:00:00

abstract：:Mood stabilizers are a category of medications used in the management of mood disorders. The mood stabilizing properties of lithium were first reported in 1949 by John Cade, and since then it has been considered the first line treatment for bipolar disorder. Despite presenting more differences than similarities, mood ...

journal_title：Neuroscience letters

authors： Pisanu C,Papadima EM,Del Zompo M,Squassina A

更新日期：2018-03-16 00:00:00

abstract：:Diabetic retinopathy is a leading cause of vision loss and blindness. Increasing evidence has shown that the neuronal components of the retina are affected even before the detection of vascular lesions. Hyperglycemia is considered the main pathogenic factor for the development of diabetic complications. Nevertheless, ...

journal_title：Neuroscience letters

authors： Baptista FI,Castilho ÁF,Gaspar JM,Liberal JT,Aveleira CA,Ambrósio AF

更新日期：2015-08-18 00:00:00

abstract：:We examined whether the mGluR1 and mGluR5 were involved in development and maintenance of behavioral signs of non-evoked pain and secondary mechanical hyperalgesia induced by knee joint inflammation. Selective mGluR1 antagonist, (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA: 50, 100, 200 microM/25 microl, n=10 per gro...

journal_title：Neuroscience letters

authors： Lee KS,Kim J,Yoon YW,Lee MG,Hong SK,Han HC

更新日期：2007-04-12 00:00:00

abstract：:[3H] Overflow evoked by 5 min supramaximal preganglionic stimulation at 1 pps has been studied in isolated guinea pig superior cervical ganglion preparations preincubated with [3H]choline. At 15 microM norepinephrine (NE) reduced both the [3H]choline overflow and endogenous acetylcholine release by 59.4 and 54.1% resp...

journal_title：Neuroscience letters

authors： Belluzzi O,Travagli RA,Bonifazzi C,Perri V

更新日期：1987-01-02 00:00:00