Expression of intrinsic bursting properties in neurons of maturing sensorimotor cortex.

Abstract:

:Intrinsically bursting (IB) neurons, responding with a burst of action potentials to just threshold intracellular depolarizing current pulses, are encountered in layer V of mature rodent sensorimotor cortex. We report the results of intracellular recordings performed on neocortical slices obtained from immature rats between postnatal day (P) 7 and P21, as compared to adult animals (above P60). The bursting properties are here reported to mature abruptly around P14. After this time a subpopulation of IB neurons was recognizable on the basis of both physiological and morphological characteristics (i.e. extensive apical and basal dendrites arborization, axon collaterals limited to layers V-VI). Maturational changes in number and distribution of Ca2+/K+ channels may account for this developmental step. The immaturity of IB neurons may be correlated with the poorly synchronized character of cortical activities in the very young animals.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Franceschetti S,Buzio S,Sancini G,Panzica F,Avanzini G

doi

10.1016/0304-3940(93)90551-u

subject

Has Abstract

pub_date

1993-11-12 00:00:00

pages

25-8

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(93)90551-U

journal_volume

162

pub_type

杂志文章
  • Acupuncture at SI5 attenuates morphine seeking behavior after extinction.

    abstract::Our previous studies have shown that acupuncture attenuates morphine self-administration and sensitization behavior as well as withdrawal signs. The present study was designed to investigate the role of acupuncture in the reinstatement of morphine seeking. Male Sprague-Dawley rats weighing 270-300 g were subjected to ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.09.020

    authors: Lee BH,Ma JH,In S,Kim HY,Yoon SS,Jang EY,Yang CH

    更新日期:2012-10-31 00:00:00

  • Acetylcholine excites identified septo-hippocampal neurons in the rat.

    abstract::Neurons of the medial septum-nucleus of the diagonal band of Broca (vertical limb) area were identified as septo-hippocampal neurons by antidromic electrical activation in anesthetized rats. A large majority of these presumably cholinergic neurons could be excited by the iontophoretic application of acetylcholine or c...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90126-x

    authors: Dutar P,Lamour Y,Jobert A

    更新日期:1983-12-23 00:00:00

  • Tau gene polymorphisms and apolipoprotein E epsilon4 may interact to increase risk for Alzheimer's disease.

    abstract::In an effort to analyze the genetic role of tau in Alzheimer's disease (AD), 17 polymorphisms were identified. Eleven of these polymorphisms were in complete linkage disequilibrium and segregated as two haplotypes, A and B. The A and B haplotypes were investigated in 269 AD cases and 238 controls from two different so...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00833-2

    authors: Lilius L,Froelich Fabre S,Basun H,Forsell C,Axelman K,Mattila K,Andreadis A,Viitanen M,Winblad B,Fratiglioni L,Lannfelt L

    更新日期:1999-12-17 00:00:00

  • Elevated oxidation of docosahexaenoic acid, 22:6 (n-3), in brain regions of rats undergoing ethanol withdrawal.

    abstract::Ethanol withdrawal is a serious clinical problem owing in part to over stimulation of ionotropic glutamate receptors in the brain and is linked to elevated oxidative damage. In this study, we tested the hypothesis that lipid peroxidation is elevated in the brain tissue of rats fed an ethanol-containing diet for 6 week...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.06.058

    authors: Milne GL,Morrow JD,Picklo MJ Sr

    更新日期:2006-09-25 00:00:00

  • Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices.

    abstract::The neuroprotective activity of riluzole has been studied on N-methyl-D-aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. Neurodegeneration was assessed by the measurement of LDH release and histology. Veratridine-induced LDH release can be inhibited by 100 microM riluzole (-90% and...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90053-1

    authors: Malgouris C,Daniel M,Doble A

    更新日期:1994-08-15 00:00:00

  • Postcentral neurons of alert monkeys activated by the contact of the hand with objects other than the monkey's own body.

    abstract::In the caudal postcentral finger region near or in the anterior bank of the intraparietal sulcus of alert monkeys, we found neurons that were activated selectively by the contact of the hand to certain common objects such as bottle brushes, acrylic plates, parts of the stabilized monkey's chair, etc. All of these neur...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11302-d

    authors: Iwamura Y,Tanaka M,Hikosaka O,Sakamoto M

    更新日期:1995-02-17 00:00:00

  • Electric field stimulation induced neuronal differentiation of filum terminale derived neural progenitor cells.

    abstract::Adult filum terminale (FT) is an atypical region from where multipotent neural progenitor cells (NPCs) have been isolated. However, poor neuronal differentiation rate of FT-NPCs currently limits their clinical applications. Using custom-designed electric fields (EFs), this study sets up a method to significantly impro...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.05.001

    authors: Dong ZY,Pei Z,Li Z,Wang YL,Khan A,Meng XT

    更新日期:2017-06-09 00:00:00

  • Brain derived neurotrophic factor does not act on adult human cerebral endothelial cells.

    abstract::Brain derived neurotrophic factor (BDNF), known to promote survival of neurons, has recently been involved in the regulation of endothelial cells and was shown to possess immunoregulatory properties. We therefore asked whether BDNF has immunoregulating effects in human cerebral endothelial cells (HCEC). Adult HCEC exp...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00778-4

    authors: Ruprecht K,Stadelmann C,Hummel V,Klein O,Brück W,Rieckmann P

    更新日期:2002-09-20 00:00:00

  • Amyloid beta-protein precursor deposition in rat hippocampus lesioned by ibotenic acid injection.

    abstract::Ibotenic acid was injected into 3 parts of the lateral rat hippocampus. The animals were sacrificed 100 days after treatment, and studied immunohistochemically. The lesioned side of the hippocampus was highly atrophic with extensive neuronal loss and gliosis. Although silver staining revealed no particular structures ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90656-r

    authors: Nakamura Y,Takeda M,Niigawa H,Hariguchi S,Nishimura T

    更新日期:1992-02-17 00:00:00

  • Extracellular taurine increase in rat hippocampus evoked by specific glutamate receptor activation is related to the excitatory potency of glutamate agonists.

    abstract::Taurine increases in brain extracellular space due to glutamate agonists were studied in vivo in the rat hippocampus using a dialysis technique, both in the absence and in the presence of glutamate receptor antagonists. Extracellular taurine levels increased during perfusions of agonists, listed in descending order of...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90308-x

    authors: Menéndez N,Herreras O,Solis JM,Herranz AS,Martín del Río R

    更新日期:1989-07-17 00:00:00

  • Staurosporine and H7 attenuate ethanol-induced elevation in [Ca2+]i in cultured canine cerebral vascular smooth muscle cells.

    abstract::Chronic exposure of cultured canine cerebral vascular smooth muscle cells to ethanol (10-400 mM) for 1-5 days resulted in significant concentration-dependent elevation in resting intracellular free calcium ([Ca2+]i) levels. Preincubation of these cultured vascular cells with inhibitors of protein kinase C (PKC), staur...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00016-0

    authors: Zheng T,Li W,Zhang A,Altura BT,Altura BM

    更新日期:1998-01-30 00:00:00

  • Cortical and medullary somatosensory projections to the cochlear nuclear complex in the hedgehog tenrec.

    abstract::Various tracer substances were injected into the spinal cord, the dorsal column nuclei, the trigeminal nuclear complex and the somatosensory cortex in Madagascan hedgehog tenrecs. With the exception of the cases injected exclusively into the spinal cord all injections gave rise to sparse, but distinct anterograde proj...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(96)13305-x

    authors: Wolff A,Künzle H

    更新日期:1997-01-17 00:00:00

  • Inter-limb transfer of kinematic adaptation in individuals with motor difficulties.

    abstract::A previous study suggested that adults with greater motor difficulties demonstrated less adaptation under a regular error feedback schedule (gain=1:1) but reached a similar level of adaptation compared to controls when feedback was enhanced (gain=1:2). In light of these findings, the present study examined inter-limb ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.06.030

    authors: Bo J,Lee CM

    更新日期:2017-07-27 00:00:00

  • Purified high molecular weight synthetic Aβ(1-42) and biological Aβ oligomers are equipotent in rapidly inducing MTT formazan exocytosis.

    abstract::Synthetic soluble Aβ oligomers are often used as a surrogate for biologic material in a number of model systems. We compared the activity of Aβ oligomers (synthetic and cell culture media derived) on the human SH-SY5Y neuroblastoma and C2C12 mouse myoblast cell lines in a novel, modified MTT assay. Separating oligomer...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.03.082

    authors: Weidner AM,Housley M,Murphy MP,Levine H 3rd

    更新日期:2011-06-15 00:00:00

  • Acetylcholinesterase staining of the human amygdala.

    abstract::This paper describes in detail the acetylcholinesterase (AChE) staining characteristics of the normal human amygdaloid complex using fixed post-mortem brain tissue. It was shown that the differential AChE staining of the amygdala could be used to accurately delineate amygdaloid subdivisions macroscopically. Using the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(85)80097-5

    authors: Svendsen CN,Bird ED

    更新日期:1985-03-15 00:00:00

  • Blocking actions of picrotoxinin analogues on insect (Periplaneta americana) GABA receptors.

    abstract::Five picrotoxinin analogues were examined on GABA-gated chloride channels of an identifiable cockroach (Periplaneta americana) motor neurone (Df). Substitution of the bridgehead hydroxyl at the C-6 position of the picrotoxinin molecule by a fluorine atom (fluoropicrotoxinin) had little effect, whereas acetylation of t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90606-8

    authors: Anthony NM,Holyoke CW Jr,Sattelle DB

    更新日期:1994-04-25 00:00:00

  • Modulation of corticospinal excitability during positive and negative motor imageries.

    abstract::We investigated corticospinal excitability during positive (execution) and negative (suppression) imageries for the right and left upper and lower limbs. In the Positive Imagery tasks, sixteen subjects were instructed to repeatedly imagine rotation of the index finger of the right or left hand, or the ankle of the rig...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2018.02.036

    authors: Yokota H,Mizuguchi N,Kakigi R,Nakata H

    更新日期:2018-04-13 00:00:00

  • Kainate-induced functional deficits are not blocked by MK-801.

    abstract::Male, Fischer-344 rats were pretreated with MK-801 (0.1, 1.0 or 10.0 mg/kg, i.p.) prior to bilateral injection of kainate (0.33 micrograms/site) into the dorsal and ventral hippocampus. Kainate impaired the acquisition of a water maze acquisition task 4 weeks after surgery, an effect not attenuated by pretreatment wit...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90018-5

    authors: Rogers BC,Tilson HA

    更新日期:1990-02-16 00:00:00

  • Noradrenergic modulation of human cortex excitability by the presynaptic alpha(2)-antagonist yohimbine.

    abstract::The objective of this study was to determine if yohimbine, a central norepinephrine enhancing drug, increases cortico-motoneuronal excitability in intact humans. Transcranial magnetic stimulation was used to assess excitability of the motor system reflected in the parameters motor threshold, recruitment curve, intraco...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01921-8

    authors: Plewnia C,Bartels M,Cohen L,Gerloff C

    更新日期:2001-07-06 00:00:00

  • Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells.

    abstract::Acrolein-induced oxidative stress is hypothesized to involve in the etiology of Alzheimer's disease (AD). Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) have antioxidative and neuroprotective properties. The present study investigated the protective effects of CA/CAPE on acrolein-induced oxidative neuronal ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.12.051

    authors: Huang Y,Jin M,Pi R,Zhang J,Chen M,Ouyang Y,Liu A,Chao X,Liu P,Liu J,Ramassamy C,Qin J

    更新日期:2013-02-22 00:00:00

  • Molecular and functional identification of a mitochondrial ryanodine receptor in neurons.

    abstract::Mitochondrial Ca(2+) controls numerous cell functions, such as energy metabolism, reactive oxygen species generation, spatiotemporal dynamics of Ca(2+) signaling, cell growth and death in various cell types including neurons. Mitochondrial Ca(2+) accumulation is mainly mediated by the mitochondrial Ca(2+) uniporter (M...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.05.026

    authors: Jakob R,Beutner G,Sharma VK,Duan Y,Gross RA,Hurst S,Jhun BS,O-Uchi J,Sheu SS

    更新日期:2014-07-11 00:00:00

  • Protein kinase G increases AMPA receptor GluR1 phosphorylation at serine 845 after repeated cocaine administration in the rat nucleus accumbens.

    abstract::The regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluR1 subunit phosphorylation at serine 845 (GluR1-Ser845) by protein kinase G (PKG) activation was investigated in the nucleus accumbens (NAc) after repeated cocaine administration. Intra-NAc injection of the cyclic guanosine monop...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.04.003

    authors: Seo SY,Oh JH,Choe ES

    更新日期:2013-06-07 00:00:00

  • Decreased somatostatin immunoreactivity but not neuropeptide Y immunoreactivity in cerebral cortex in senile dementia of Alzheimer type.

    abstract::The content of two neuropeptides, somatostatin (SRIF) and neuropeptide Y (NPY) has been determined in two cerebral cortical areas of Alzheimer's disease brain and in age-matched control brains. The content of SRIF-like immunoreactivity (SRIF-LI) was found to be decreased in Alzheimer temporal cortex (Brodmann area 21)...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90455-6

    authors: Dawbarn D,Rossor MN,Mountjoy CQ,Roth M,Emson PC

    更新日期:1986-09-25 00:00:00

  • Sleep deprivation induces changes in 5-HT actions and 5-HT1A receptor expression in the rat hippocampus.

    abstract::A 12h sleep deprivation enhances the expression of 5-hydroxytryptamine (5-HT) 1A receptors in rat hippocampus that recedes with 48h sleep recovery. The depressant effect of applied 5-HT on the field excitatory postsynaptic potentials recorded in the CA1 area, is also enhanced in hippocampi of SD rats. Following a 24 o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.06.053

    authors: Azizi H,Hwang J,Suen V,Kang NZ,Somvanshi R,Tadavarty R,Kumar U,Sastry BR

    更新日期:2017-08-10 00:00:00

  • The effect of somatostatin on striatal catecholamines.

    abstract::Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90034-x

    authors: Beal MF,Martin JB

    更新日期:1984-02-24 00:00:00

  • GABAρ3 expression in lobule X of the cerebellum is reduced in the valproate model of autism.

    abstract::Autism spectrum disorder (ASD) is a group of developmental disorders characterized by social interaction deficits, communication impairments, and stereotyped and repetitive behaviors. Additionally, impairments in the GABAergic circuitry have been associated with ASD. Several studies have shown that dysfunction of the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2018.09.042

    authors: Varman DR,Soria-Ortíz MB,Martínez-Torres A,Reyes-Haro D

    更新日期:2018-11-20 00:00:00

  • Dyslexics show a deviant lateralization of attentional control: a brain potential study.

    abstract::The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.10.072

    authors: Wijers AA,Been PH,Romkes KS

    更新日期:2005-02-10 00:00:00

  • Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases.

    abstract::Nitric oxide (NO) from endothelial or neuronal NO synthases (eNOS or nNOS) may contribute both to the cerebrovascular responses to oxygen and potentially to the peroxynitrite-mediated toxic effects of hyperbaric oxygen (HBO(2)) on the central nervous system (CNS O(2) toxicity). In mice lacking eNOS or nNOS (-/-), regi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00432-4

    authors: Demchenko IT,Atochin DN,Boso AE,Astern J,Huang PL,Piantadosi CA

    更新日期:2003-06-19 00:00:00

  • Altered white matter integrity in young adults with first-episode, treatment-naive, and treatment-responsive depression.

    abstract::Abnormalities of the white matter (WM) tracts integrity in brain areas involved in emotional regulation have been postulated in major depressive disorder (MDD). However, there is no diffusion tensor imaging (DTI) study in patients with treatment-responsive MDD at present. DTI scans were performed on 22 patients with t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.06.027

    authors: Guo WB,Liu F,Xue ZM,Gao K,Wu RR,Ma CQ,Liu ZN,Xiao CQ,Chen HF,Zhao JP

    更新日期:2012-08-01 00:00:00

  • Continuous exposure to dim illumination uncouples temporal patterns of sleep, body temperature, locomotion and drinking behavior in the rat.

    abstract::Dissociable circadian rhythms of sleep and body temperature in primates are thought to be regulated by independent oscillators whereas the uncoupling of circadian rhythms has not been well described in other mammals. Therefore, we made simultaneous recordings of non-rapid-eye-movement-sleep (NREMS), rapid-eye-movement...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00943-x

    authors: Ikeda M,Sagara M,Inoué S

    更新日期:2000-02-04 00:00:00