Altered white matter integrity in young adults with first-episode, treatment-naive, and treatment-responsive depression.

abstract：:Epileptiform activity is a state often induced in vitro in order to study seizures and antiepileptic/anticonvulsant drugs. Traditional methods of evaluating drug effects have commonly relied upon measuring changes in the frequency and duration of such events. We have used a recently developed mathematical technique ba...

journal_title：Neuroscience letters

authors： Harrison PK,Tattersall JE,Clement RA

更新日期：2004-03-11 00:00:00

abstract：:ATP is an important extracellular messenger in the CNS. In the hippocampus, a brain structure relevant for learning and memory processes, it acts both as a modulator and as a mediator of synaptic transmission, with implications for synaptic plasticity phenomena. Recent evidence suggests that ATP modulates activity-dep...

journal_title：Neuroscience letters

authors： da Silva BM,de Mendonça A,Ribeiro JA

更新日期：2005-08-05 00:00:00

abstract：:The distribution of premotor neurons projecting to motor nuclei of both the VIIth (VII) and XIIth (XII) nerves was examined in the pontomedullary reticular formation (RF) of the rat by using retrograde double labeling. After injection of two different tracers in the VII and the XII, most of the double labeled neurons ...

journal_title：Neuroscience letters

authors： Dauvergne C,Pinganaud G,Buisseret P,Buisseret-Delmas C,Zerari-Mailly F

更新日期：2001-09-28 00:00:00

abstract：:By observing the ultrastructural intracellular Ca2+ distribution with Ca(2+)-oxalate-pyroantimonate method, we examined whether the protective mechanism of the nitric oxide (NO) synthase inhibitor, N omega-nitro-L-arginine (LNNA), involves change of the intracellular Ca2+ movement in delayed neuronal death (DND) in ge...

journal_title：Neuroscience letters

authors： Kohno K,Higuchi T,Ohta S,Kohno K,Kumon Y,Sakaki S

更新日期：1997-03-07 00:00:00

abstract：:Somatosensory amplification refers to the tendency to experience benign and ambiguous somatic sensation as intense, noxious, and disturbing. The construct is helpful in assessing the perceptual style of a variety of somatizing conditions, but there is no human study clarifying the effects of neurological function on s...

journal_title：Neuroscience letters

authors： Nakao M,Barsky AJ,Nishikitani M,Yano E,Murata K

更新日期：2007-03-26 00:00:00

abstract：:Olfactory bulb-protein tyrosine phosphatase (OB-PTP) is a receptor type PTPase dominantly expressed in olfactory bulb. Previously, we isolated and molecularly cloned a rat OB-PTP cDNA from an embryonal brain cDNA library. In the present study, we investigated its temporal and spatial gene expression by Northern blot a...

journal_title：Neuroscience letters

authors： Yahagi Y,Tagawa M,Tomoda T,Shirasawa T

更新日期：1996-06-21 00:00:00

abstract：:This study was designed toinvestigate the efficacy of adenovirus vector-mediated brain-derived neurotrophic factor (BDNF) ex vivo gene transfer to human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) in a rat sciatic nerve crush injury model. BDNF protein and mRNA expression after infection was checked...

journal_title：Neuroscience letters

authors： Hei WH,Almansoori AA,Sung MA,Ju KW,Seo N,Lee SH,Kim BJ,Kim SM,Jahng JW,He H,Lee JH

更新日期：2017-03-16 00:00:00

abstract：:The role of the dorsal hippocampus in the different stages of blocking was examined in a taste aversion learning task. Blocking is a learning effect in which one previously conditioned element of a compound makes the conditioning of the added element difficult. An effective blocking procedure with one trial in each st...

journal_title：Neuroscience letters

authors： Gallo M,Cándido A

更新日期：1995-02-15 00:00:00

abstract：:The membrane mechanisms associated with Cl- conductance activated by GABA in spinal and hippocampal neurons cultured from the embryonic mouse and rat have been studied with voltage- and patch-clamp techniques. The elementary mechanism underlying the conductance response is predominantly all-or-none with both similar a...

journal_title：Neuroscience letters

authors： Barker JL,Owen DG,Segal M

更新日期：1984-06-29 00:00:00

abstract：:Blood-brain barrier (BBB) is known to be structured with astroglial cells (AGs) and brain endothelial cells (BECs), and it has been proposed that these cells play different roles in the BBB. We cultivated AGs and BECs from infant rats (2-week-old), and these cells were cultured on the opposing side of collagen membran...

journal_title：Neuroscience letters

authors： Kondo T,Kinouchi H,Kawase M,Yoshimoto T

更新日期：1996-04-19 00:00:00

abstract：:Neuronal cell cycle activation has been implicated in neurodegenerative diseases such as Alzheimer's disease, while the initiating mechanism of cell cycle activation remains to be determined. Interestingly, our previous studies have shown that cell cycle activation by c-Myc (Myc) leads to neuronal cell death which sug...

journal_title：Neuroscience letters

authors： Lee HP,Kudo W,Zhu X,Smith MA,Lee HG

更新日期：2011-11-14 00:00:00

abstract：:The rodent gustatory cortex is located in the anterior part of the insular cortex, which is near the dorsal part of the rhinal vein (RHV) and the intersection of the anterior and posterior regions of the middle cerebral artery (MCA). Thus, the intersection between the RHV and MCA is used as a landmark for the rodent g...

journal_title：Neuroscience letters

authors： Kida I,Enmi J,Iida H,Yoshioka Y

更新日期：2015-03-04 00:00:00

abstract：:In the present study we sought to investigate the signal transduction mechanisms that underlie the alpha2-adrenergic receptor (AR)-induced, subtype-specific neuronal differentiation of PC12 cells. Alpha2-ARs induced NF-kappaB transcriptional activity and p21(waf-1) gene transcription in the same subtype-specific manne...

journal_title：Neuroscience letters

authors： Lymperopoulos A,Karkoulias G,Koch WJ,Flordellis CS

更新日期：2006-07-24 00:00:00

abstract：:The effect of prenatal ethanol exposure on the number of parvalbumin-immunoreactive (PA+) GABAergic neurons in the adult rat anterior cingulate cortex was determined. Pregnant Long-Evans rats were maintained on one of three diets throughout gestation: an ethanol-containing liquid diet, a similar, control liquid diet w...

journal_title：Neuroscience letters

authors： Moore DB,Quintero MA,Ruygrok AC,Walker DW,Heaton MB

更新日期：1998-06-12 00:00:00

abstract：:Surround inhibition (SI) is a neural mechanism to focus neuronal activity and facilitate selective motor execution (ME). The aim of the present study was to investigate whether SI is also generated during motor imagery (MI). Furthermore, we investigated whether the extent of SI during MI depends on the strength of SI ...

journal_title：Neuroscience letters

authors： Aoyama T,Kaneko F,Ohashi Y,Nagata H

更新日期：2016-08-26 00:00:00

abstract：:In this study, the notion of additivity in perception of affect from limb motion is investigated. Specifically, we examine whether the impact of multiple limbs in perception of affect is equal to the sum of the impacts of each individual limb. Several neutral, happy, and sad walking sequences are first aligned and ave...

journal_title：Neuroscience letters

authors： Etemad SA,Arya A,Parush A

更新日期：2014-01-13 00:00:00

abstract：:Phosphoramidon (100-350 micrograms i.c.v.), a selective enkephalinase inhibitor, induced in the rat a decrease of nociception to pressure stimulation without evident respiratory depression. In addition, intensive behavioural changes such as grooming (licking the fur, face washing and scratching), mounting behaviour an...

journal_title：Neuroscience letters

authors： Rupreht J,Ukponmwan OE,Admiraal PV,Dzoljic MR

更新日期：1983-11-11 00:00:00

abstract：:The uptake of 2-deoxy-[14C]glucose (2-DG) by motor neurons in adult rat hypoglossal nuclei was studied 3 days after subepineural injection of 'crude' soluble protein extracts from intact and injured peripheral nerves into normal hypoglossal nerves. Injured nerve extracts were obtained from 'proximal' and 'distal' segm...

journal_title：Neuroscience letters

authors： Singer PA,Mehler S,Fernandez HL

更新日期：1988-01-22 00:00:00

abstract：:Recent studies have demonstrated that genetic factors modify susceptibility to sporadic Parkinson's disease (PD). So far the results of candidate gene studies have been conflicting. It has been suggested that polymorphisms in apolipoprotein E (APOE), PARKIN and catechol-O-methyltransferase (COMT) genes might increase ...

journal_title：Neuroscience letters

authors： Eerola J,Launes J,Hellström O,Tienari PJ

更新日期：2002-09-27 00:00:00

abstract：:This study was designed to assess whether phencyclidine (PCP)-induced head-twitch was antagonized by ritanserin, a selective serotonin (5-HT2) receptor antagonist, in mice and rats to confirm the involvement of 5-hydroxytryptamine (5-HT) neurons in PCP actions in comparison with 5-methoxy-N,N-dimethyltryptamine (5-MeO...

journal_title：Neuroscience letters

authors： Nabeshima T,Ishikawa K,Yamaguchi K,Furukawa H,Kameyama T

更新日期：1987-05-19 00:00:00

abstract：:The acute thermoregulatory effect of microinjection of capsaicin into the nucleus raphe dorsalis (NRD) has been studied in anesthetised rats. Application of capsaicin (20 micrograms) into the NRD increased the tail skin temperature and decreased the body temperature. In animals that had previously been treated with ca...

journal_title：Neuroscience letters

authors： Hajós M,Hjorth S,Carlsson A

更新日期：1987-03-31 00:00:00

abstract：:To study the neuronal mechanism of a conditioned taste-aversion (CTA) learning in the pond snail Lymnaea stagnalis, we examined the synaptic connection between the neuron 1 medial (N1M) cell and the cerebral giant cell (CGC), the former is an interneuron in central pattern generator for the feeding response and the la...

journal_title：Neuroscience letters

authors： Kojima S,Nanakamura H,Nagayama S,Fujito Y,Ito E

更新日期：1997-07-25 00:00:00

abstract：:Glucose uptake is increased during motoneuron regeneration. Since this glucose is probably used as an energy source for axonal regeneration we postulated that hypoglycemia might interfere with motoneuron regeneration. In order to partially test this hypothesis we attempted to induce moderate hypoglycemia by fasting ra...

journal_title：Neuroscience letters

authors： Singer PA,Mehler S

更新日期：1983-10-31 00:00:00

abstract：:Neocortical neurofibrillary tangles (NFT) revealed by Bodian technique and anti-tau immunolabelling were seen in 5/5 cases of progressive supranuclear palsy (PSP) aged 58-76 years. These lesions differed from Alzheimer's disease or age-related changes: (1) they were most frequent in the precentral gyrus (Brodmann's ar...

journal_title：Neuroscience letters

authors： Hauw JJ,Verny M,Delaère P,Cervera P,He Y,Duyckaerts C

更新日期：1990-11-13 00:00:00

abstract：:Expression by rat motoneurons of mRNAs for the alpha subunit of the ciliary neurotrophic factor receptor (CNTFR alpha), receptor tyrosine kinase-C (trkC), calcitonin gene-related peptide (CGRP) and galanin was studied by in situ hybridisation, 6d after rat facial nerve transection on postnatal day 1. Similar numbers o...

journal_title：Neuroscience letters

authors： Duberley RM,Johnson IP

更新日期：1996-11-08 00:00:00

abstract：:As a prevalent disease all over the world, changed functional activities and/or structures in many brain regions have been found in depression. In this study, 5-week chronic restraint stress (CRS) was performed to establish depression rat models, and 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) wa...

journal_title：Neuroscience letters

authors： Wei K,Bao W,Zhao Z,Zhou W,Liu J,Wei Y,Li M,Wu X,Liu B,Du Y,Gong W,Dong J

更新日期：2018-02-05 00:00:00

abstract：:The present study is designed to screen the effect of syringin, an active principle purified from the rhizome and root parts of Eleutherococcus senticosus (Araliaceae), on the plasma glucose and investigate the possible mechanisms. Plasma glucose decreased in a dose-dependent manner 60 min after intravenous injection ...

journal_title：Neuroscience letters

authors： Liu KY,Wu YC,Liu IM,Yu WC,Cheng JT

更新日期：2008-03-28 00:00:00

abstract：:Sapogenins from Anemarrhenae asphodeloides was reported to improve the learning and memory abilities. In this study, we investigated the effect of Timosaponin B-II(TB-II), a purified extract from A. asphodeloidesb on rat vascular dementia (VD) produced by transient (2h) middle cerebral artery occlusion. The learning a...

journal_title：Neuroscience letters

authors： Li TJ,Qiu Y,Yang PY,Rui YC,Chen WS

更新日期：2007-06-27 00:00:00

abstract：:We investigated the role of local cutaneous signals and of co-contraction of antagonists in repeated judgements of heaviness of weights lifted by flexor pollicis longus. A reference weight lifted by right thumb flexion was matched to a weight lifted by left thumb flexion. Anaesthesia of the right thumb, or of the supe...

journal_title：Neuroscience letters

authors： Kilbreath SL,Gandevia SC,Wirianski A,Hewitt B

更新日期：1995-12-15 00:00:00

abstract：:Periostin has dual roles as a multifunctional cytokine and an extracellular matrix protein that binds to several integrins on a variety of cells. This study evaluated whether the expression and cellular localization of periostin changes in the spinal cord of mice with experimental autoimmune encephalomyelitis (EAE), a...

journal_title：Neuroscience letters

authors： Choi Y,Kim J,Ahn M,Shin T

更新日期：2020-01-10 00:00:00