Effect of phosphoramidon - a selective enkephalinase inhibitor - on nociception and behaviour.

abstract：:Gangliosides are sialic acid-containing sphingolipids that have promoting effects on the survival, growth, and functions of neurons in the central nervous system. Glial cells including astrocytes assist neurons with regard to their proliferation, maintenance, and function. In the present study, we found that astrocyte...

journal_title：Neuroscience letters

authors： Akasako Y,Nara K,Nagai Y,Hashimoto Y

更新日期：2011-01-20 00:00:00

abstract：:This study compared the immediate and prolonged effects of acute bouts of active and passive leg cycling on the soleus H-reflex among 12 young healthy men. The soleus H-reflex was measured immediately before and then 10 and 30 min after 20 min of active, unloaded leg cycling, passively induced leg cycling, and quiet r...

journal_title：Neuroscience letters

authors： Motl RW,Knowles BD,Dishman RK

更新日期：2003-08-21 00:00:00

abstract：:It has long been known that primary neurons in the brain and spinal cord exhibit very distinctive dendritic structures. However, it remains unclear whether dendritic processing for signal propagation and channel activation over dendrites is a function of the cell type-specific dendritic structure. By applying an exten...

journal_title：Neuroscience letters

authors： Kim H,Heckman CJ

更新日期：2015-11-16 00:00:00

abstract：:Two antidystrophin antibodies against different fragments of dystrophin were used to detect this polypeptide in monkey and human brains. Dystrophin was revealed by immunoperoxidase amplified with the biotin/avidin system and by immunoblotting. A dystrophin-like immunoreactivity was uniformly expressed in several brain...

journal_title：Neuroscience letters

authors： Huard J,Côté PY,Parent A,Bouchard JP,Tremblay JP

更新日期：1992-07-20 00:00:00

abstract：:To investigate the working mechanism of the conflict processing system, pairs of colored numbers were sequentially presented on a screen to subjects. They were asked to determine if the magnitude or the color of the two numbers was identical. Event-related potentials (ERPs) were recorded at the same time. A negative p...

journal_title：Neuroscience letters

authors： Wang H,Wang Y,Kong J,Cui L,Tian S

更新日期：2001-02-09 00:00:00

abstract：:The effects of morphine (0.2-200 micrograms/kg) administered into the brain stem via a vertebral artery on the somatosympathetic A- and C-reflexes evoked in a cardiac sympathetic nerve by electrical stimulation of somatic myelinated (A) and unmyelinated (C) afferent nerve fibers in anesthetized cats were examined. The...

journal_title：Neuroscience letters

authors： Kato J,Meguro K,Sato A,Sato Y

更新日期：1992-04-27 00:00:00

abstract：:Protein kinase G (PKG) has been implicated in a variety of physiological functions including synaptic plasticity in the brain. This study investigated the involvement of dopamine D3 (D3) receptors in PKG-regulated dopamine release, long-term changes in gene expression and behavioral sensitization after repeated cocain...

journal_title：Neuroscience letters

authors： Lee DK,Oh JH,Yang JH,Youn B,Shim YB,Shim I,Wang JQ,Choe ES

更新日期：2013-04-29 00:00:00

abstract：:Paramethoxyphenylethylamine (PMPEA) is a sympathomimetic amine, like its parent compound, phenylethylamine. The intraperitoneal administration of PMPEA to mice produces a dose-dependent depletion of brain and heart norepinephrine, with significant reduction being observed one hour postinjection. At lower dosages, PMPE...

journal_title：Neuroscience letters

authors： Ashkenazi R,Haber B

更新日期：1975-09-01 00:00:00

abstract：:The medial prefrontal cortex (mPFC) is thought to exert inhibitory control over stress-induced activation of the amygdala and neurocognitive effects. As evidence to support this, we examined how exposure to either a brief or prolonged stress affected on amygdalar c-Fos levels and recognition memory of animals with mPF...

journal_title：Neuroscience letters

authors： Park JC,Jeon YJ,Kim JJ,Cho J,Choi DH,Han JS

更新日期：2020-09-14 00:00:00

abstract：:In the course of our survey of natural compounds inhibiting prostaglandin E2 release and/or lipopolysaccharide (LPS)-induced transcriptional stimulation via NF-kappaB, a central regulator of inflammatory genes, from natural resources, we found garcinone B, a xanthone from callus tissue culture of Hypericum patulum, as...

journal_title：Neuroscience letters

authors： Yamakuni T,Aoki K,Nakatani K,Kondo N,Oku H,Ishiguro K,Ohizumi Y

更新日期：2006-02-20 00:00:00

abstract：:Interhemispheric coherence for 19 channel EEG activity collected over a three year period from 184 men and women who relaxed in a quiet, darkened chamber showed significant increased coherence between caudal temporal regions for the 11 Hz frequency band during increased (>∼8 nT) global geomagnetic activity at the time...

journal_title：Neuroscience letters

authors： Saroka KS,Caswell JM,Lapointe A,Persinger MA

更新日期：2014-02-07 00:00:00

abstract：OBJECTIVE:To investigate the protective effect of gliclazide and the role of dynamin-related protein l (Drp-1)-mediated oxidative stress and apoptosis in diabetic peripheral neuropathy (DPN). METHODS:Diabetic rats developed through intra-peritoneal injection of streptozotocin were randomly assigned to treatment group ...

journal_title：Neuroscience letters

authors： Wu YB,Shi LL,Wu YJ,Xu WH,Wang L,Ren MS

更新日期：2012-08-08 00:00:00

abstract：:Many studies have shown that minocycline, an antibacterial tetracycline, suppresses experimental pain. While minocycline's positive effects on pain resolution suggest that clinical use of such drugs may prove beneficial, minocycline's antibiotic actions and divalent cation (Ca(2+); Mg(2+)) chelating effects detract fr...

journal_title：Neuroscience letters

authors： Bastos LF,Godin AM,Zhang Y,Jarussophon S,Ferreira BC,Machado RR,Maier SF,Konishi Y,de Freitas RP,Fiebich BL,Watkins LR,Coelho MM,Moraes MF

更新日期：2013-05-24 00:00:00

abstract：:We evaluated the effect of cabergoline on superoxide anion production by rat microglial cells using a 2-methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1, 2-a]pyrazin-3-one-dependent chemiluminescence assay. Cabergoline dose-dependently inhibited superoxide anion production by microglial cells stimulated with phorbol my...

journal_title：Neuroscience letters

authors： Yoshida T,Tanaka M,Suzuki Y,Sohmiya M,Okamoto K

更新日期：2002-09-13 00:00:00

abstract：:Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during ...

journal_title：Neuroscience letters

authors： Ramírez-Rodríguez G,Vega-Rivera NM,Benítez-King G,Castro-García M,Ortíz-López L

更新日期：2012-11-14 00:00:00

abstract：:Administration of the cannabinoid CB1 receptor antagonist SR141716 (3-10 mg/kg i.p.) abolished neuropeptide Y-induced overeating and significantly reduced ethanol and sucrose intake in CB1 wild-type (+/+) mice. In CB1 receptor knockout (-/-) mice, neuropeptide Y totally lost its capacity to increase food consumption. ...

journal_title：Neuroscience letters

authors： Poncelet M,Maruani J,Calassi R,Soubrié P

更新日期：2003-06-12 00:00:00

abstract：:We report a sporadic case of tauopathy with unusual clinical and neuropathological features. The patient presented with progressive symmetric rigid-akinetic parkinsonism and dementia of the subcortical type. Magnetic resonance imaging of the brain revealed atrophy resembling multiple system atrophy. The level of cereb...

journal_title：Neuroscience letters

authors： Ohara S,Tsuyuzaki J,Oide T,Arai H,Higuchi S,Hasegawa M,Iwatsubo T

更新日期：2002-09-13 00:00:00

abstract：:We identified a 45-kDa protein by 2D electrophoresis that was enhanced following pentylenetetrazol (PTZ)-mediated seizures. Mass-spectrography of this protein revealed the beta subunit of Ca2+/calmodulin-dependent protein kinase II (CaMKIIbeta), although no evidence for increase in bulk CaMKIIbeta transcripts was obta...

journal_title：Neuroscience letters

authors： Matsu-ura T,Nakadai T,Oda Y,Nagasu T,Mikoshiba K,Tamura TA

更新日期：2002-04-12 00:00:00

abstract：:In this study we reported evidence for the existence of specific binding sites for platelet-activating factor (PAF) in neuroblastoma N1E-115 cells. The specific [3H]PAF binding reached a steady state level within 60 min at 25 degrees C. Scatchard analysis of the specific [3H]PAF binding revealed the presence of two ap...

journal_title：Neuroscience letters

authors： Lalouette F,Diserbo M,Martin C,Verdetti J,Fatome M

更新日期：1995-02-17 00:00:00

abstract：:A high expression of PrP(C) in cells is one factor that increases the risk of conversion to the misfolded, disease-associated form (PrP(Sc)) characteristic of transmissible spongiform encephalopathies. Thus, developing a method to control the level of PrP(C) expression in cells could be one way to delay or prevent the...

journal_title：Neuroscience letters

authors： Zawlik I,Witusik M,Hulas-Bigoszewska K,Piaskowski S,Szybka M,Golanska E,Liberski PP,Rieske P

更新日期：2006-05-29 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a common disorder of cognitive functions in aged patients following anesthesia and surgery. α7-nicotinic acetylcholine receptors (α7-nAChR) plays a regulatory role in cognitive processes and is involved in cognitive deficits. This study aims to observe the effect of electr...

journal_title：Neuroscience letters

authors： Liu PR,Zhou Y,Zhang Y,Diao S

更新日期：2017-10-17 00:00:00

abstract：:The slow Wallerian degeneration protein (WldS), a fusion protein containing amino-terminal E4B and full-length nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), delays axon degeneration caused by physical damages, toxins and genetic mutations which result in patients being diagnosed with neurodegenerative di...

journal_title：Neuroscience letters

authors： Watanabe M,Tsukiyama T,Hatakeyama S

更新日期：2007-01-16 00:00:00

abstract：:In this study, the notion of additivity in perception of affect from limb motion is investigated. Specifically, we examine whether the impact of multiple limbs in perception of affect is equal to the sum of the impacts of each individual limb. Several neutral, happy, and sad walking sequences are first aligned and ave...

journal_title：Neuroscience letters

authors： Etemad SA,Arya A,Parush A

更新日期：2014-01-13 00:00:00

abstract：:In the rat the response of suprachiasmatic nucleus neurons to steady retinal illumination at different adaptation luminances was studied. The results confirm that in this nucleus the discharge rate is more commonly increased than suppressed by light. Interval histograms indicate that a complex process underlies the di...

journal_title：Neuroscience letters

authors： Groos G,Mason R

更新日期：1978-04-01 00:00:00

abstract：:Genetic polymorphisms in chemokine receptor and their natural ligand genes have been shown to modify the disease progression of Alzheimer's disease (AD). Human macrophage inflammatory protein-1 alpha (MIP-1alpha) is a chemotactic cytokine which plays a considerable role in AD pathogenesis, but its genetic contribution...

journal_title：Neuroscience letters

authors： Li K,Dai D,Yao L,Gu X,Luan K,Tian W,Zhao Y,Wang B

更新日期：2008-03-12 00:00:00

abstract：:The effect of chronic salt loading on urocortin-like immunoreactivity (Ucn-IR) was investigated in the rat hypothalamo-neurohypophysial system. In control rats a few Ucn-IR neurons were observed scattered throughout the supraoptic nucleus (SON) and few in the paraventricular nucleus (PVN). A small number of Ucn-IR fib...

journal_title：Neuroscience letters

authors： Hara Y,Ueta Y,Isse T,Kabashima N,Shibuya I,Hattori Y,Yamashita H

更新日期：1997-05-16 00:00:00

abstract：:The relation between phantom limb pain (PLP) and the movement representation of a phantom limb remains controversial in several areas of neurorehabilitation, although there are a few studies in which the representation of phantom limb movement was precisely evaluated. We evaluated the structured movement representatio...

journal_title：Neuroscience letters

authors： Osumi M,Sumitani M,Wake N,Sano Y,Ichinose A,Kumagaya S,Kuniyoshi Y,Morioka S

更新日期：2015-09-25 00:00:00

abstract：:The effects of microiontophoretic application of 5-hydroxytryptamine (5-HT) on the neuronal firing rate of the medial vestibular nucleus (MVN) were studied in anaesthetized rats. Ninety-three % of the units modified their background activity following 5-HT iontophoresis, enhancements of the firing rate being recorded ...

journal_title：Neuroscience letters

authors： Licata F,Li Volsi G,Maugeri G,Santangelo F

更新日期：1993-05-14 00:00:00

abstract：:Ischemic cerebrovascular diseases, usually involved in hypoxia and reoxygenation, have been reported to increase the risk of dementia such as Alzheimer's disease (AD). beta-site amyloid protein precursor (APP)-cleaving enzymes (BACE1) have been identified to participate in the secretion of beta-amyloid peptides (Abeta...

journal_title：Neuroscience letters

authors： Xue S,Jia L,Jia J

更新日期：2006-09-25 00:00:00

abstract：:The prioritized processing of threat is suggested to be motivated by anxiety, regulated by the parasympatheticus, and biased to the right hemisphere. However, according to an anterior dimensional model of negative affect this is unlikely to be true when threat is of social origin. Social threat is communicated by the ...

journal_title：Neuroscience letters

authors： van Honk J,Hermans EJ,d'Alfonso AA,Schutter DJ,van Doornen L,de Haan EH

更新日期：2002-02-15 00:00:00