The effects of morphine administered into the vertebral artery on the somatosympathetic A- and C-reflexes in anesthetized cats.

abstract：:Noise-induced hearing loss (NIHL) severely impacts the quality of life of affected individuals. Oxidative stress resulting from noise exposure is a significant cause of NIHL. Although histone deacetylase (HDAC) inhibitors were shown to protect against NIHL, the underlying mechanism remains unclear, and it is not known...

journal_title：Neuroscience letters

authors： Yang DH,Xie J,Liu K,Peng Z,Guo JY,Yu SK,Wang GP,Gong SS

更新日期：2017-11-01 00:00:00

abstract：:Wild-type neuronal calcium-binding protein VILIP (visinin-like protein), and a myristoylation mutant of VILIP which lacks the consensus sequence for N-terminal myristoylation, have been stably transfected in PC12 cells. Immunocytochemical studies of VILIP-transfected PC12 cells have revealed the wild-type VILIP is str...

journal_title：Neuroscience letters

authors： Spilker C,Gundelfinger ED,Braunewell KH

更新日期：1997-04-04 00:00:00

abstract：:We have previously used antisense oligodeoxynucleotides (ODN) to the cloned delta opioid receptor (DOR) to inhibit the antinociceptive response to spinally administered delta opioid receptor selective agonists in mice. Here we have examined the effect of DOR antisense ODN treatment on the level of DOR expressed in NG ...

journal_title：Neuroscience letters

authors： Lai J,Riedl M,Stone LS,Arvidsson U,Bilsky EJ,Wilcox GL,Elde R,Porreca F

更新日期：1996-08-09 00:00:00

abstract：:L-Histidine decarboxylase catalyzes the formation of histamine from the amino acid L-histidine. We have studied the distribution of neurons expressing mRNA for histidine decarboxylase in adult rat brain using in situ hybridization with synthetic oligonucleotide probes. The expression of mRNA for histidine decarboxylas...

journal_title：Neuroscience letters

authors： Castrén E,Panula P

更新日期：1990-11-27 00:00:00

abstract：:Alterations of Ca2+ homeostasis have been reported for both fibroblasts and T-lymphocytes of patients with Alzheimer's disease (AD). Considering the importance of K+ conductances for the cellular Ca2+ regulation and the recently reported absence of a K+ channel in Alzheimer fibroblasts, we investigated K+ currents in ...

journal_title：Neuroscience letters

authors： Cohen CD,Vollmayr B,Aldenhoff JB

更新日期：1996-01-05 00:00:00

abstract：:Following unilateral electrolytic lesioning of the rat entorhinal cortex, we assessed changes in messenger RNA (mRNA) levels for four neuron-associated proteins, GAP-43, SCG10, 68 kDa neurofilament (NF68), and alpha 1-tubulin that encode proteins of importance to synaptic remodelling. The mRNA levels for GAP-43 and SC...

journal_title：Neuroscience letters

authors： Zarow C,Finch CE

更新日期：1995-02-09 00:00:00

abstract：:The levels of apoptosis associated proteins Bcl(2), Bax, cytochrome-c and p53 was investigated in mice cerebral cortex and cerebellum, using an experimental model of fatal murine cerebral malaria (FMCM). Owing to the activation of events central to mitochondrial dysfunctions, we monitored the structural integrity of m...

journal_title：Neuroscience letters

authors： Kumar KA,Babu PP

更新日期：2002-09-06 00:00:00

abstract：:2-Deoxy-d-glucose (2DG) is an analog of glucose that is effectively taken up by cells competing with normal glucose but cannot be further utilized to produce energy. It was previously reported that 2DG can mimic the beneficial effects of dietary restriction in experimental models of neurodegenerative disorders and can...

journal_title：Neuroscience letters

authors： Park M,Song KS,Kim HK,Park YJ,Kim HS,Bae MI,Lee J

更新日期：2009-01-16 00:00:00

abstract：:We previously obtained evidence that in rats the neurons in the suprachiasmatic nucleus (SCN) receiving retinal neural inputs may be involved in the regulation of glucose metabolism. In this study we examined whether the SCN neurons containing vasoactive intestinal peptide (VIP)-like immunoreactive substance (VIP neur...

journal_title：Neuroscience letters

authors： Shimizu K,Hibino H,Komenami N,Nagai N,Nagai K,Nakagawa H

更新日期：1994-07-04 00:00:00

abstract：:The effects of methamphetamine (MAP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in the rat brain. A single administration of MAP induced dose-dependent and reversible increases in NTLI in the caudate-putamen, limbic forebrain and midbrain. NTLI in the caudate-putamen, limbic forebrain...

journal_title：Neuroscience letters

authors： Wachi M,Okuda M,Togashi S,Miyashita O,Wakahoi T

更新日期：1987-07-22 00:00:00

abstract：:Astrocytes have been implicated in axon guidance and synaptic regeneration in the retina and these processes involve activation of the high affinity nerve growth factor receptor, known as the tyrosine kinase A (TrkA) receptor. The purpose of the present study was to characterize the expression of TrkA in astrocytes of...

journal_title：Neuroscience letters

authors： Ruiz-Ederra J,Hitchcock PF,Vecino E

更新日期：2003-02-13 00:00:00

abstract：:The human nervous system displays remarkable functional plasticity following long-term sensory deprivation. For example, the auditory cortex of congenitally deaf humans may start to process tactile information. To further explore this type of cross-modal plasticity, we examined the tactile accuracy of congenitally dea...

journal_title：Neuroscience letters

authors： Levänen S,Hamdorf D

更新日期：2001-03-23 00:00:00

abstract：:Neurocalcin, a newly discovered calcium-binding protein belonging to the recoverin-like superfamily, was detected immunohistochemically in tufted cells from the rat olfactory bulb. More precisely, only periglomerular tufted cells and some tufted cells from the external plexiform layer were expressing neurocalcin. West...

journal_title：Neuroscience letters

authors： Bastianelli E,Okazaki K,Hidaka H,Pochet R

更新日期：1993-10-29 00:00:00

abstract：:Unilateral movements are enabled through a distributed network of motor cortical areas but the relative contribution from the parts of this network is largely unknown. Failure of this network potentially results in mirror activation of the primary motor cortex (M1) ipsilateral to the intended movement. Here we tested ...

journal_title：Neuroscience letters

authors： Cincotta M,Borgheresi A,Balestrieri F,Giovannelli F,Rossi S,Ragazzoni A,Zaccara G,Ziemann U

更新日期：2004-09-02 00:00:00

abstract：:Substance P (SP) stimulates striatal dopamine outflow through a cholinergic muscarinic link. SP-induced increase in acetylcholine (Ach) is concentration-dependent, whereas the stimulation of dopamine outflow is seen only over a limited concentration range. M(1) and M(2) receptor stimulation has opposite effects on dop...

journal_title：Neuroscience letters

authors： Khan S,Whelpton R,Michael-Titus AT

更新日期：2000-11-03 00:00:00

abstract：:On the basis of our previous observations which indicated that transforming growth factor beta1 (TGFbeta1) affects the gene expression and the release of luteinizing hormone-releasing hormone (LHRH) in GT1-1 cells, we have presently evaluated whether also TGFbeta2 might be effective on these parameters. The data here ...

journal_title：Neuroscience letters

authors： Messi E,Galbiati M,Magnaghi V,Zucchi I,Martini L,Melcangi RC

更新日期：1999-08-06 00:00:00

abstract：:Simultaneous recordings of cortical activity, recorded as the cortical local field potential (CLFP) in the contralateral posterior sigmoid gyrus, and the spinal activity, recorded as the cord dorsum potential (CDP) of the L6 lumbar segment, were made in the anaesthetized cat. The electrodes were positioned in somatose...

journal_title：Neuroscience letters

authors： Manjarrez E,Rojas-Piloni G,Vazquez D,Flores A

更新日期：2002-02-01 00:00:00

abstract：:Dietary flavonoids, including the citrus flavanone hesperetin, may have stimulatory effects on cytoprotective intracellular signalling pathways. In primary mouse cortical neurone cultures, but not SH-SY5Y human neuroblastoma cells or human primary dermal fibroblasts (Promocells), hesperetin (100-300nM, 15min) caused s...

journal_title：Neuroscience letters

authors： Rainey-Smith S,Schroetke LW,Bahia P,Fahmi A,Skilton R,Spencer JP,Rice-Evans C,Rattray M,Williams RJ

更新日期：2008-06-13 00:00:00

abstract：:Alpha-2 macroglobulin (A2M) is a component of Lewy bodies, a hallmark of Parkinson's disease (PD). In 159 PD patients and 190 normal controls, we studied two A2M polymorphisms by the polymerase chain reaction-restriction fragment length polymorphism method: a five-nucleotide deletion at the 5' splice site of exon 18; ...

journal_title：Neuroscience letters

authors： Nicoletti G,Annesi G,Tomaino C,Spadafora P,Pasqua AA,Annesi F,Serra P,Caracciolo M,Messina D,Zappia M,Quattrone A

更新日期：2002-08-02 00:00:00

abstract：:This study was designed to investigate the effects of honokiol, a neuroprotective agent, on cerebral edema in cerebral ischemia reperfusion (IR) mice and its mechanism of anti-inflammation. Honokiol (0.7-70μg/kg) significantly reduced brain water contents and decreased the exudation of Evans blue dye from brain capill...

journal_title：Neuroscience letters

authors： Zhang P,Liu X,Zhu Y,Chen S,Zhou D,Wang Y

更新日期：2013-02-08 00:00:00

abstract：:Light microscopic immunohistochemistry was used to investigate the presence and distribution of chromogranin A-like immunoreactivity in the human anal canal. In the anal transitional zone (ATZ), anal duct and anal gland epithelium, a varied number of mostly elongated cells strongly stained for CGA, using an antibody d...

journal_title：Neuroscience letters

authors： Weihe E,Hörsch D,Eiden LE,Hartschuh W

更新日期：1991-09-16 00:00:00

abstract：:The effect of acute phenylethanolamine-N-methyltransferase (PNMT) inhibition on rat brain catecholamine concentrations was studied. All PNMT inhibitors tested were effective in depleting hypothalamic and brain stem epinephrine. Norepinephrine concentrations were unaffected; however, dopamine levels were increased in a...

journal_title：Neuroscience letters

authors： Mefford IN,Roth KA,Barchas JD

更新日期：1980-10-20 00:00:00

abstract：:The effects of various Flustra foliacea metabolites on different types of human neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes were investigated. Whereas most of the compounds tested had a small blocking effect, one of them, deformylflustrabromine, selectively increased the current ob...

journal_title：Neuroscience letters

authors： Sala F,Mulet J,Reddy KP,Bernal JA,Wikman P,Valor LM,Peters L,König GM,Criado M,Sala S

更新日期：2005-01-10 00:00:00

abstract：:Visual P300 responses were recorded by using checkerboard-type stimuli. (1) High amplitude P300-delta responses were visible even in single trial event-related potentials (ERPs). (2) The algorithm based on the 'delta response metric' provides an efficient selection criterion for evaluation of P300 single trials in ERP...

journal_title：Neuroscience letters

authors： Schürmann M,Başar-Eroglu C,Kolev V,Başar E

更新日期：1995-09-15 00:00:00

abstract：:Age-related neurodegenerative diseases are of critical concern to the general population and research/medical community due to their health impact and socioeconomic consequences. A feature of most, if not all, neurodegenerative disorders is the presence of proteinopathies, in which misfolded or conformationally altere...

journal_title：Neuroscience letters

authors： Chung KM,Hernández N,Sproul AA,Yu WH

更新日期：2019-04-01 00:00:00

abstract：:Occurrence of neurocalcin, a calcium-binding protein with three EF hand motifs, was examined immunohistochemically in the rat olfactory epithelium and vomeronasal organ epithelium. Immunoreactivity was detected in receptor cells in these epithelia. Immunoreactions were distributed in cytoplasm associated with outer mi...

journal_title：Neuroscience letters

authors： Iino S,Kobayashi S,Okazaki K,Hidaka H

更新日期：1995-05-19 00:00:00

abstract：:The IKK/NF-κB signalling pathway plays a predominant role in the regulation of inflammation and apoptosis in spinal cord injury (SCI). We have previously demonstrated that targeting of the IKK/NF-κB pathway improved the recovery of locomotor function by reducing the infiltration of inflammatory cells and apoptosis aft...

journal_title：Neuroscience letters

authors： Lu M,Wang S,Han X,Lv D

更新日期：2013-05-10 00:00:00

abstract：:Substance P immunoreactivity has been detected in varicosities around cell bodies of the nucleus dorsalis (Clarke's column) of the human spinal cord. This immunostaining probably represents neuropeptide immunoreactivity either in the nerve terminals of spinal interneurone, descending projections or in the primary dors...

journal_title：Neuroscience letters

authors： Pioro EP,Hughes JT,Cuello AC

更新日期：1984-09-28 00:00:00

abstract：:The injection of oxytocin into the third ventricle during suckling in lactating rats not only enhances neurosecretory bursts but also the background activity of oxytocin cells. However, removing the young rats 10 min after the oxytocin injection is immediately followed by a decrease in background activity, while injec...

journal_title：Neuroscience letters

authors： Meyer C,Freund-Mercier MJ,Richard P

更新日期：1987-03-20 00:00:00

abstract：:Narcolepsy is characterized, beside other features, by excessive daytime sleepiness and disturbed sleep at night. The pineal hormone melatonin may affect the sleep characteristics. The aim of the study was to compare the circadian rhythm in salivary melatonin in narcoleptic patients with that in control healthy subjec...

journal_title：Neuroscience letters

authors： Blazejova K,Illnerova H,Hajek I,Nevsimalova S

更新日期：2008-05-30 00:00:00