Increase of urocortin-like immunoreactivity in the rat hypothalamo-neurohypophysial system after salt loading and hypophysectomy.

abstract：:Five monkeys vocalizing at self-pace (self-paced vocalization) were well trained to vocalize in response to a monkey call (audio-initiated vocalization). Field potentials associated with audio-initiated vocalizations were recorded by using electrodes which were implanted chronically on the surface and at a 2.0-3.0 mm ...

journal_title：Neuroscience letters

authors： Gemba H,Kyuhou S,Matsuzaki R,Amino Y

更新日期：1999-09-03 00:00:00

abstract：:We looked for an interaction between etifoxine and the neurosteroid allopregnanolone at central gamma-aminobutyric acid (GABA(A)) receptors. Etifoxine (2 microM) did not affect the affinity of allopregnanolone (IC(50)=108 nM) for its site in preparations of Sprague-Dawley rat cerebral cortex membranes, as determined b...

journal_title：Neuroscience letters

authors： Verleye M,Schlichter R,Neliat G,Pansart Y,Gillardin JM

更新日期：2001-04-06 00:00:00

abstract：:We isolated nardosinone as a neuritogenic substance from Nardostachys chinensis. Nardosinone did not exhibit the neurotrophic activity but caused a marked enhancement of the nerve growth factor (NGF)-mediated neurite outgrowth from PC12D cells. Nardosinone-induced enhancement of the NGF-action was completely blocked b...

journal_title：Neuroscience letters

authors： Li P,Matsunaga K,Yamamoto K,Yoshikawa R,Kawashima K,Ohizumi Y

更新日期：1999-09-24 00:00:00

abstract：:A marked depression of evoked CA1 potentials was observed with the nucleotide analogues a,b-methylene ADP (AOPCP) and adenylimido-diphosphate (AIP) and with 2'-adenosine monophosphate (2'-AMP). While the depression elicited by 5'-nucleotides was completely antagonized by the action of adenosine deaminase, AOPCP and 2'...

journal_title：Neuroscience letters

authors： Lee KS,Schubert P,Emmert H,Kreutzberg GW

更新日期：1981-05-29 00:00:00

abstract：:Adult mouse sciatic nerves (SNs) with attached dorsal root ganglia (DRG) were analysed for the presence of mitogen activated protein kinase (MAP-K) during normal and regenerative conditions. By immunohistochemistry, MAP-K was found to be present in the normal nerve at low levels in both Schwann cells and DRG nerve cel...

journal_title：Neuroscience letters

authors： Svensson B,Ekström PA,Edström A

更新日期：1995-11-10 00:00:00

abstract：:In experiments using a synaptosomal preparation from the striatum and nucleus accumbens, somatostatin caused a dose-dependent increase in dopamine synthesis. This increase was additive with that produced by 8-BrcAMP but not with that produced by the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA), and was bl...

journal_title：Neuroscience letters

authors： Chowdhury M,Steardo L,Fillenz M

更新日期：1987-11-23 00:00:00

abstract：:The purpose of this study was to investigate how the recruitment gain, as derived from the Hoffmann (H)-reflex measurement, of antagonistic motoneurons is modulated during voluntary lengthening (LEN) and shortening (SHO) contractions in the human tibialis anterior (TA) muscle. To this end, the parameters of the ratios...

journal_title：Neuroscience letters

authors： Sekiguchi H,Nakazawa K,Akai M

更新日期：2003-05-15 00:00:00

abstract：:Carvedilol's potent antioxidant activity could explain its protective action in brain ischemia, but may not apply to glutamate-induced excitotoxicity in cultured cerebellar granule cells, since glutamate neurotoxicity was not associated with the formation of lipid peroxidative products. Rather, carvedilol diminished t...

journal_title：Neuroscience letters

authors： Lysko PG,Lysko KA,Webb CL,Feuerstein G

更新日期：1992-12-14 00:00:00

abstract：:Lithium has been successfully employed therapeutically for treatment of bipolar depressive illness; however, its mechanism of action is poorly understood. Recently, it has been demonstrated by us that lithium can prevent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) dopaminergic neurotoxicity in mice. From analy...

journal_title：Neuroscience letters

authors： Arraf Z,Amit T,Youdim MB,Farah R

更新日期：2012-05-10 00:00:00

abstract：:[3H]Nitrendipine bound to cerebral cortex membranes is displaced more efficiently by verapamil in old rats (24 months old) compared to young ones (3 months old). In addition, [3H]verapamil binding was studied in detail in 3-, 12- and 24-month-old rats. Aging increases the Bmax of [3H]verapamil, leaving the affinity un...

journal_title：Neuroscience letters

authors： Battaini F,Govoni S,Rius RA,Trabucchi M

更新日期：1985-10-24 00:00:00

abstract：:The present study was designed to determine potential associations between the brain damage induced by hypoxic-ischemic (HI) insult and spatial learning impairment in an eight-arm radial maze task. We first determined the pathological outcomes after 2, 5, 9, and 17 weeks of recovery following the HI insult. The result...

journal_title：Neuroscience letters

authors： Mishima K,Ikeda T,Aoo N,Takai N,Takahashi S,Egashira N,Ikenoue T,Iwasaki K,Fujiwara M

更新日期：2005-03-16 00:00:00

abstract：:Neurodegenerative disorders such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are characterized by impairment of autophagy. Cellular survival is dependent on efficient clearance of phosphorylated α-synuclein, which accumulates as fibrils in the neuronal cytoplasm as Lewy bodies (LBs). The forkhead b...

journal_title：Neuroscience letters

authors： Miki Y,Tanji K,Mori F,Utsumi J,Sasaki H,Kakita A,Takahashi H,Wakabayashi K

更新日期：2018-09-25 00:00:00

abstract：:Kynurenic acid (KYNA), a neuroactive metabolite of tryptophan that acts on different receptors (e.g. those of N-methyl-D-aspartate (NMDA) and presynaptic α7 nicotinic acetylcholine (nACh)), exerts fundamentally antiglutamatergic effects. In view of its antiglutamatergic properties, an elevation of the KYNA level withi...

journal_title：Neuroscience letters

authors： Demeter I,Nagy K,Farkas T,Kis Z,Kocsis K,Knapp L,Gellert L,Fülöp F,Vecsei L,Toldi J

更新日期：2013-10-11 00:00:00

abstract：:Transcriptomic studies of murine D3 embryonic stem (ES) cells deficient in the purinergic biosynthetic function hypoxanthine guanine phosphoribosyltransferase (HPRT) and undergoing dopaminergic neuronal differentiation has demonstrated a marked shift from neuronal to glial gene expression and aberrant expression of mu...

journal_title：Neuroscience letters

authors： Kang TH,Friedmann T

更新日期：2015-03-17 00:00:00

abstract：:We examined the rubrospinal projection to forelimb motoneurons (Mns) in cats, in comparison with the corticospinal projection. Under pentobarbital anesthesia, intracellular recordings were made from forelimb Mns following stimulation of the red nucleus (RN) and the cerebral peduncle (CP). Single pulse stimulation of t...

journal_title：Neuroscience letters

authors： Fujito Y,Imai T,Aoki M

更新日期：1991-06-10 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) has been rediscovered as a hormone and immunomodulator as well as a proinflammatory cytokine. We investigated the expression of MIF protein and mRNA in the rat brain using optimized immunohistochemistry and in situ hybridization, respectively. By immunohistochemical analysi...

journal_title：Neuroscience letters

authors： Ogata A,Nishihira J,Suzuki T,Nagashima K,Tashiro K

更新日期：1998-05-01 00:00:00

abstract：:Tryptophan hydroxylase 2 (TPH2) is a rate-limiting enzyme of neuronal serotonin biosynthesis. Recently, two single nucleotide polymorphisms (SNPs) at the exon 11 coding region that resulted in amino acid substitutions in the C-terminal domain have been reported to affect enzyme activity in humans and mice. We determin...

journal_title：Neuroscience letters

authors： Hong KW,Sugawara Y,Hasegawa H,Hayasaka I,Hashimoto R,Ito S,Inoue-Murayama M

更新日期：2007-02-02 00:00:00

abstract：:The sensory neurons in the trigeminal ganglion which project to the muscles of mastication of the cat were studied using the retrograde transport of horseradish peroxidase. Horseradish peroxidase either was injected directly into the masticatory muscles or applied to the nerves supplying them. Numerous retrogradely la...

journal_title：Neuroscience letters

authors： Martin JW,Panneton WM

更新日期：1986-10-20 00:00:00

abstract：:The effects of various Flustra foliacea metabolites on different types of human neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes were investigated. Whereas most of the compounds tested had a small blocking effect, one of them, deformylflustrabromine, selectively increased the current ob...

journal_title：Neuroscience letters

authors： Sala F,Mulet J,Reddy KP,Bernal JA,Wikman P,Valor LM,Peters L,König GM,Criado M,Sala S

更新日期：2005-01-10 00:00:00

abstract：:Sexual receptivity was suppressed in female rats immediately after the male had ejaculated. The inhibition was prevented by intravaginal injection of naloxone (100 micrograms) before testing and intravaginal injection of beta-endorphin (1.0 micrograms) inhibited sexual behavior in female rats in a manner comparable to...

journal_title：Neuroscience letters

authors： Forsberg G,Bednar I,Eneroth P,Södersten P

更新日期：1990-07-17 00:00:00

abstract：:To study the central effects of adenosine on hypoxia, the influence of treatment by the A1 receptor agonist cyclohexyladenosine (1 microM) or by the antagonist theophylline (10 microM) was tested on cell damage in a model of neuronal culture. Whereas theophylline enhanced cell injury induced by 8 h hypoxia, cyclohexyl...

journal_title：Neuroscience letters

authors： Daval JL,Nicolas F

更新日期：1994-07-04 00:00:00

abstract：:Maternal infection during pregnancy increases the risk of neurodevelopmental conditions such as autism spectrum disorders and schizophrenia in offspring. Several previous animal studies have indicated that maternal immune activation (MIA), rather than a specific pathogen, alters fetal brain development. Among them, pr...

journal_title：Neuroscience letters

authors： Zuiki M,Chiyonobu T,Yoshida M,Maeda H,Yamashita S,Kidowaki S,Hasegawa T,Gotoh H,Nomura T,Ono K,Hosoi H,Morimoto M

更新日期：2017-07-13 00:00:00

abstract：:Orexins (OXs) stimulate sympathetic nerve activity to increase arterial pressure (AP) and heart rate (HR). We have previously reported that the OX(1)-receptor antagonist SB-334867 reversed the sympathomimetic actions of orexin A (OXA). In the present study we have investigated the role(s) of the orexinergic system in ...

journal_title：Neuroscience letters

authors： Hirota K,Kushikata T,Yoshida H,Kudo M,Kudo T

更新日期：2008-02-20 00:00:00

abstract：:Mammalian olfactory sensory neurons (OSNs), the primary elements of the olfactory system, are located in the olfactory epithelium lining the nasal cavity. Exposed to the environment, their lifespan is short. Consequently, OSNs are regularly regenerated and several reports show that activity strongly modulates their de...

journal_title：Neuroscience letters

authors： Molinas A,Aoudé I,Soubeyre V,Tazir B,Cadiou H,Grosmaitre X

更新日期：2016-07-28 00:00:00

abstract：:The high-affinity of [3H]gamma-aminobutyric acid (GABA) to GABAA receptors and [3H]baclofen to GABAB receptors were studied in the cerebellum of pyridoxine-deficient rats and compared to pyridoxine-supplemented controls. There was a significant increase in the maximal binding (Bmax) of both GABAA and GABAB receptors w...

journal_title：Neuroscience letters

authors： Paulose CS,Dakshinamurti K

更新日期：1984-08-10 00:00:00

abstract：:Oxidative stress has been projected as a promising mechanism involved in lead exposure. The lead predisposition catalyzes oxidative reactions and generates reactive oxygen species. The present study was carried out to investigate the effect of oral administration of tannic acid (TA) on behavioral deficit, antioxidativ...

journal_title：Neuroscience letters

authors： Ashafaq M,Tabassum H,Vishnoi S,Salman M,Raisuddin S,Parvez S

更新日期：2016-03-23 00:00:00

abstract：:This study investigated differences in the neural time-course of cognitive conflict and emotional conflict control, using event-related potentials (ERPs). Although imaging studies have provided some evidence that distinct, dissociable neural systems underlie emotional and nonemotional conflict resolution, no ERP study...

journal_title：Neuroscience letters

authors： Xue S,Li Y,Kong X,He Q,Liu J,Qiu J

更新日期：2016-04-21 00:00:00

abstract：:We examined the effects of chronic in vivo antipsychotic drug treatments on G protein function and regulation. Mice were treated with typical antipsychotic haloperidol (6 mg/kg per day) and atypical agent olanzapine (20 mg/kg per day) for 14 days via mini-osmotic pumps. G protein-activated adenylyl cyclase activity in...

journal_title：Neuroscience letters

authors： Kaplan GB,Leite-Morris KA,Keith DJ

更新日期：1999-10-08 00:00:00

abstract：:MicroRNAs (miRNAs) are small noncoding RNAs that function as tumor suppressors or oncogenes. MicroRNA-107 (miR-107), a transcriptional target of p53, is deregulated in many cancer cell lines. Here, we showed that miR-107 is down-regulated in glioma tissues and cell lines, in particular, p53-mutated U251 and A172. Tran...

journal_title：Neuroscience letters

authors： Chen L,Zhang R,Li P,Liu Y,Qin K,Fa ZQ,Liu YJ,Ke YQ,Jiang XD

更新日期：2013-02-08 00:00:00

abstract：:Many recent studies have revealed the consistency of anticipatory postural adjustments preceding single leg movements, such as stepping, in standing humans. These adjustments appear to involve an active lateral transfer of weight to the stance leg. The present study demonstrates that these anticipatory adjustments oft...

journal_title：Neuroscience letters

authors： McIlroy WE,Maki BE

更新日期：1993-12-24 00:00:00