A clinical and neuropathological study of an unusual case of sporadic tauopathy. A variant of corticobasal degeneration?

abstract：:The roles of the endogenous adenosine on acetylcholine release via adenosine A1 receptor were investigated in rat cerebral cortex using brain microdialysis. Oral administration of KF15372 (8-dicyclopropylmethyl-1,3-dipropylxanthine), a novel selective adenosine A1 receptor antagonist, at doses of 1.25, 5, and 20 mg/kg...

journal_title：Neuroscience letters

authors： Kurokawa M,Shiozaki S,Nonaka H,Kase H,Nakamura J,Kuwana Y

更新日期：1996-05-17 00:00:00

abstract：:The AMPA receptor subunit GluR2 is downregulated in neurons following a wide range of neurological insults. Here we report that suppression of GluR2 gene promoter activity is associated with kainate (KA)-induced downregulation of GluR2 subunit levels in primary cultured cortical neurons. RT-PCR and Northern blotting s...

journal_title：Neuroscience letters

authors： Jia YH,Zhu X,Li SY,Ni JH,Jia HT

更新日期：2006-07-31 00:00:00

abstract：:In rats anesthetized with pentobarbital or a mixture of urethane and chloralose, horseradish peroxidase (HRP) was injected into the intermediolateral column of the spinal cord (Th7 and Th9) or the posterior pituitary lobe. HRP positive cells were found mainly in the dorsomedial part of the paraventricular nuclease (PV...

journal_title：Neuroscience letters

authors： Ono T,Nishino H,Sasaka K,Muramoto K,Yano I,Simpson A

更新日期：1978-11-01 00:00:00

abstract：:Aluminum and zinc are two important trace elements in an organism. Although several studies have demonstrated their impacts on the intelligence, very little was known about their effects on the integrity of blood-brain barrier (BBB). To study the effects of aluminum and zinc on the permeability of BBB, different doses...

journal_title：Neuroscience letters

authors： Song Y,Xue Y,Liu X,Wang P,Liu L

更新日期：2008-11-07 00:00:00

abstract：:Age dependent EEG signatures were detected in the EEG of 71 neonates of 28-100 weeks of conceptional age (CA). Using the new method presented, neonates were automatically classified in three age groups (28-35 weeks CA), (36-40 weeks CA) and (41-100 weeks CA). Analysis was performed employing relative distance function...

journal_title：Neuroscience letters

authors： Holthausen K,Breidbach O,Scheidt B,Frenzel J

更新日期：1999-06-25 00:00:00

abstract：:Precise evaluation of the ascending reticular activating system (ARAS) is important for diagnosis, prediction of prognosis, and management of patients with disorders of impaired consciousness. In the current study, we attempted to reconstruct the direct neural pathway between the brainstem reticular formation (RF) and...

journal_title：Neuroscience letters

authors： Jang SH,Kwon HG

更新日期：2015-10-08 00:00:00

abstract：:The brains of 7 dogs aged 6 to 18 years have been histochemically and immunohistochemically investigated at the light- and electron microscopy levels for preamyloid deposits and amyloid fibrils to verify the hypothesis that the accumulation of cleavage products of amyloid precursor protein is related not only to Alzhe...

journal_title：Neuroscience letters

authors： Giaccone G,Verga L,Finazzi M,Pollo B,Tagliavini F,Frangione B,Bugiani O

更新日期：1990-07-03 00:00:00

abstract：:Fluoride-resistant acid phosphatase (FRAP) has been suggested as an enzymatic marker for nociceptive primary afferent terminals in the spinal dorsal horn, however there has not been demonstrated a direct functional relation between FRAP activity and an increased nociceptive transmission. For this purpose, we quantitat...

journal_title：Neuroscience letters

authors： Glykys J,Guadama M,Marcano L,Ochoa E,Eblen-Zajjur A

更新日期：2003-02-13 00:00:00

abstract：:Intracellular recordings from luminosity-type horizontal cells of the turtle retina were used to analyze the effects of steady and flickering background illumination on the size of their receptive fields. Both types of background illumination reduce the size of the receptive field to about the same extent. The reducti...

journal_title：Neuroscience letters

authors： Weiler R,Akopian A

更新日期：1992-06-08 00:00:00

abstract：:Acute physical exercise (APE) induces an increase in the individual alpha peak frequency (iAPF), a cortical parameter associated with neural information processing speed. The aim of this study was to further scrutinize the influence of different APE intensities on post-exercise iAPF as well as its time course after ex...

journal_title：Neuroscience letters

authors： Gutmann B,Zimmer P,Hülsdünker T,Lefebvre J,Binnebößel S,Oberste M,Bloch W,Strüder HK,Mierau A

更新日期：2018-03-06 00:00:00

abstract：:L1 is a highly conserved cell adhesion molecule with complete homology of the cytoplasmic domain between the known mammalian protein sequences. Since the cytoplasmic domains of other adhesion molecules have been shown to influence adhesion, we have investigated the effects of deletion of the cytoplasmic domain on the ...

journal_title：Neuroscience letters

authors： Wong EV,Cheng G,Payne HR,Lemmon V

更新日期：1995-11-24 00:00:00

abstract：:We compared, for a number of ligands to the two receptors, the displacement of [3H]strychnine binding to the glycine-gated chloride channel of spinal cord and brainstem synaptic membranes to the displacement of [3H]glycine binding to the NMDA receptor complex of hippocampal and cortex synaptic membranes. Glycine and b...

journal_title：Neuroscience letters

authors： Pullan LM,Powel RJ

更新日期：1992-12-14 00:00:00

abstract：:Stimulation of type-1 astrocytes, by a number of agonists, has been shown to increase cytosolic Ca2+ concentrations in an oscillatory manner. However, it is unknown how these are driven or altered by aging, injury or disease. Therefore, we characterized the signaling properties of rat type-1 astrocytes in monolayer cu...

journal_title：Neuroscience letters

authors： Johnston JM,Burnett P,Thomas AP,Tezapsidis N

更新日期：2006-03-06 00:00:00

abstract：:Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...

journal_title：Neuroscience letters

authors： Sun J,Ling Z,Wang F,Chen W,Li H,Jin J,Zhang H,Pang M,Yu J,Liu J

更新日期：2016-02-02 00:00:00

abstract：:We have used Lucifer Yellow for histological tracing of displaced amacrine cells within the ganglion cell layer (GCL) during the embryonic development of the chicken retina. Incubating whole eyes in the dye leads to bright staining of all displaced amacrine cells, whereas ganglion cells and glial cells are not stained...

journal_title：Neuroscience letters

authors： Layer PG,Vollmer G

更新日期：1982-08-16 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels which mediate fast cholinergic synaptic transmission in insect and vertebrate nervous systems. A point mutation Y151S had been identified in Nilaparvata lugens (brown planthopper) that is associated with target-site resistance to neonicotinoid in...

journal_title：Neuroscience letters

authors： Zhang Y,Liu S,Gu J,Song F,Yao X,Liu Z

更新日期：2008-12-03 00:00:00

abstract：:Bilateral injections of the GABA(A) agonist muscimol into the lateral parabrachial nucleus (LPBN) disrupt satiety and induce strong ingestion of water and 0.3M NaCl in fluid-replete rats by mechanisms not completely clear. In the present study, we investigated the effects of the blockade of central muscarinic choliner...

journal_title：Neuroscience letters

authors： Asnar DS,Roncari CF,De Luca LA Jr,de Paula PM,Colombari DS,Menani JV

更新日期：2013-02-08 00:00:00

abstract：:Cerebral ischemia-reperfusion (I/R)-induced brain tissue injury is a major obstacle for acute stroke management. Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) is reported to play a critical role in the regulation of myocardial or hepatic I/R injury. However, its role in cerebral I/R remains elu...

journal_title：Neuroscience letters

authors： Liu Y,Guo Y

更新日期：2021-01-19 00:00:00

abstract：:The survival of identified retinal ganglion cells (RGGs) in vitro increased when they were plated over subcultured monolayers of astrocytes. Immunofluorescence labelling of these monolayers showed that over 85% of the cells were glial fibrillary acidic protein (GFAP) positive and consisted of large, flat immature astr...

journal_title：Neuroscience letters

authors： McCaffery CA,Raju TR,Bennett MR

更新日期：1985-06-24 00:00:00

abstract：:We previously demonstrated the preventive effect of insulin-like growth factor 1 (IGF-1) on steroid myopathy in rats. However, the mechanism by which IGF-1 inhibits steroid myopathy remains unclear. Recent studies have revealed that glutamine synthetase (GS) is induced by glucocorticoid and may be related to the devel...

journal_title：Neuroscience letters

authors： Kimura K,Kanda F,Okuda S,Chihara K

更新日期：2001-04-20 00:00:00

abstract：:Nuclear factor kappa B (NF(kappa)B) transcription factor plays a key role in the expression of many genes involved in the inflammatory process. We used the Freund's Complete Adjuvant (FCA)-induced model of peripheral inflammation to investigate the anti-inflammatory effects of double stranded oligodeoxynucleotides (OD...

journal_title：Neuroscience letters

authors： Igwe OJ

更新日期：2005-06-10 00:00:00

abstract：:The representation of time, space and numbers are strictly linked in the primate's cognitive system. Here we show that merely looking at number symbols biases a temporal judgment on their duration depending upon the number's magnitude. In a first experiment, a group of healthy subjects was submitted to a time estimati...

journal_title：Neuroscience letters

authors： Oliveri M,Vicario CM,Salerno S,Koch G,Turriziani P,Mangano R,Chillemi G,Caltagirone C

更新日期：2008-06-27 00:00:00

abstract：:Recent evidence demonstrated that lesion-induced central nervous system changes are at least partly mediated by the action of the gaseous transmitter nitric oxide (NO). We investigated the hypothesis that the frequency of peripheral C-fibre stimulation determines the number of neurones in the dorsal horn that can be v...

journal_title：Neuroscience letters

authors： Hoheisel U,Kaske A,Reinert A,Mense S

更新日期：1997-05-23 00:00:00

abstract：:Hippocampal synaptic plasticity between Schaffer collaterals and CA1 pyramidal neurons can be induced by activation of N-methyl-d-aspartate receptors (NMDARs) or of metabotropic glutamate receptors (mGluRs). Inhibitory GABAergic interneurons in this region abundantly terminate on pyramidal neurons and may thus influen...

journal_title：Neuroscience letters

authors： Rohde M,Tokay T,Köhling R,Kirschstein T

更新日期：2009-12-18 00:00:00

abstract：:The effects of electrical stimulation of the central (CE) and basolateral (BL) amygdaloid nuclei on pancreatic exocrine secretion were tested in urethane-anesthetized rats. Electrical stimulation (0.1 mA, 1 ms, 40 Hz) of the CE significantly increased basal and hormone (secretin+cholecystokinin-8)-infused pancreatic e...

journal_title：Neuroscience letters

authors： Hahn SJ,Yoon SH,Sim SS,Rhie DJ,Jo YH,Kim MS

更新日期：1994-03-14 00:00:00

abstract：:Astrocytic glial cells from neonatal rat brains were grown in primary culture. Dipeptidyl peptidase II (DPP-II) enzyme activity was measured in cells disrupted by nonionic detergent. The rate of enzyme activity was measured in the presence of various ions, under isosmotic conditions adjusted using mannitol and NaCl. D...

journal_title：Neuroscience letters

authors： Stevens BR,Fernandez A,Sumners C,Hearing L

更新日期：1988-07-08 00:00:00

abstract：:Lesch-Nyhan syndrome (LNS), caused by the complete deficiency of hypoxanthine phosphoribosyltransferase (HPRT), is characterized by a neurological deficit, the etiology of which is still unclear. Evidence has accumulated indicating that it reflects dopamine deficiency associated with defective arborization of dopamine...

journal_title：Neuroscience letters

authors： Boer P,Brosh S,Wasserman L,Hammel I,Zoref-Shani E,Sperling O

更新日期：2001-04-27 00:00:00

abstract：:The effect of 4-aminopyridine (4-AP) on long-term potentiation (LTP) was studied in the hippocampal slice preparation of the rat. Field excitatory postsynaptic potentials (EPSPs) were recorded and evoked in the stratum radiatum of the CA1. Both the low frequency EPSP and LTP of the EPSP were significantly increased by...

journal_title：Neuroscience letters

authors： Lee WL,Anwyl R,Rowan M

更新日期：1986-09-25 00:00:00

abstract：:Typical histopathological findings of multiple system atrophy (MSA) have been observed in motor related cortices, in addition to the common areas of the striatum, substantia nigra, olivopontocerebellar pathways, the intermediolateral cell columns of the spinal cord, and the cerebellum. The purpose of this study is to ...

journal_title：Neuroscience letters

authors： You H,Wang J,Wang H,Zang YF,Zheng FL,Meng CL,Feng F

更新日期：2011-09-08 00:00:00

abstract：:Samples collected from rabbit neocortical surface during a tetanic stimulation of the neocortex induced neurite growth in PC-12 cells in culture and synaptic long-term potentiation (LTP) in guinea pig hippocampal slices. If these samples were preheated and cooled, or if they were collected in the absence of a tetanic ...

journal_title：Neuroscience letters

authors： Sastry BR,Chirwa SS,May PB,Maretić H

更新日期：1988-08-15 00:00:00