Fasting increases glucose and leucine uptake during regeneration of the hypoglossal nerve in the rat.

Abstract:

:Glucose uptake is increased during motoneuron regeneration. Since this glucose is probably used as an energy source for axonal regeneration we postulated that hypoglycemia might interfere with motoneuron regeneration. In order to partially test this hypothesis we attempted to induce moderate hypoglycemia by fasting rats for 3 days between the time of hypoglossal nerve transection and the time of [14C]2-deoxyglucose (2-DG) and [14C]leucine measurement. We transected one hypoglossal nerve, leaving the other intact, and measured the glucose uptake quantitatively or leucine uptake semiquantitatively in the hypoglossal nucleus. We found that both glucose and leucine uptake were increased in the hypoglossal nuclei during regeneration of the nerve in the fasted animals above that in the normally fed animals. This suggests that fasting creates a deficit of glucose and perhaps leucine which induces increased uptake.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Singer PA,Mehler S

doi

10.1016/0304-3940(83)90232-x

subject

Has Abstract

pub_date

1983-10-31 00:00:00

pages

115-8

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(83)90232-X

journal_volume

41

pub_type

杂志文章
  • Application of long-interval paired-pulse transcranial magnetic stimulation to motion-sensitive visual cortex does not lead to changes in motion discrimination.

    abstract::The perception of visual motion is dependent on a set of occipitotemporal regions that are readily accessible to neuromodulation. The current study tested if paired-pulse Transcranial Magnetic Stimulation (ppTMS) could modulate motion perception by stimulating the occipital cortex as participants viewed near-threshold...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2020.135022

    authors: Gamboa OL,Brito A,Abzug Z,D'Arbeloff T,Beynel L,Wing EA,Dannhauer M,Palmer H,Hilbig SA,Crowell CA,Liu S,Donaldson R,Cabeza R,Davis SW,Peterchev AV,Sommer MA,Appelbaum LG

    更新日期:2020-06-21 00:00:00

  • Changes in paradoxical sleep accompanying instrumental learning in the cat.

    abstract::Five animals were used as their own controls for a replication on cats of earlier findings of facilitated paradoxical sleep (PS) after learning. The experiment was based on an instrumental conditioning with positive reinforcement and three-hour recordings of the subsequent sleep. Facilitation was observed as (a) an in...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(76)90066-5

    authors: Lecas JC

    更新日期:1976-12-01 00:00:00

  • Phosphorylation of tau by glycogen synthase kinase 3beta in intact mammalian cells influences the stability of microtubules.

    abstract::Tau is a neuronal microtubule-associated protein found predominantly in axons. Hyperphosphorylation of tau reduces the stability of microtubules, which may be a pathogenic mechanism in Alzheimer's disease. To understand the different effects between tau and glycogen synthase kinase 3beta (GSK-3beta) phosphorylated tau...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02206-6

    authors: Sang H,Lu Z,Li Y,Ru B,Wang W,Chen J

    更新日期:2001-10-26 00:00:00

  • Coexistence of galanin and substance P in the mouse nasal mucosa, including the vomeronasal organ.

    abstract::Immunohistochemical fluorescent double labeling revealed the coexistence of galanin and substance P in nerve fibers in the mouse nasal mucosa. At the base of and in the epithelium, all galanin fibers also contained substance P, but around the blood vessels and glands, most of them did not. Since substance P fibers in ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90148-1

    authors: Matsuda H,Tsukuda M,Kadota T,Kusunoki T,Kishida R

    更新日期:1994-05-23 00:00:00

  • Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil.

    abstract::By observing the ultrastructural intracellular Ca2+ distribution with Ca(2+)-oxalate-pyroantimonate method, we examined whether the protective mechanism of the nitric oxide (NO) synthase inhibitor, N omega-nitro-L-arginine (LNNA), involves change of the intracellular Ca2+ movement in delayed neuronal death (DND) in ge...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)13459-0

    authors: Kohno K,Higuchi T,Ohta S,Kohno K,Kumon Y,Sakaki S

    更新日期:1997-03-07 00:00:00

  • N400 as an index of uncontrolled categorization processing in brand extension.

    abstract::This study examined the ERP (event-related potential) correlates of categorization processing in brand extension with irrelative task. Participants faced two sequential stimuli in a pair consisting of a soft drink brand name (S1) and a product name (S2) which comprised two categories: beverage (typical product of the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.07.043

    authors: Wang X,Ma Q,Wang C

    更新日期:2012-09-06 00:00:00

  • Alterations in white matter integrity in first-episode, treatment-naive patients with somatization disorder.

    abstract::White matter (WM) abnormality in somatization disorder (SD) has not been reported yet. This study was designed to elucidate the alterations in WM integrity in SD. A total of 25 patients with SD and 28 healthy controls were enrolled in the study. WM integrity was analyzed using tract-based spatial statistics. No differ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.05.037

    authors: Zhang J,Jiang M,Yao D,Dai Y,Long L,Yu M,Liu J,Zhang Z,Xiao C,Guo W

    更新日期:2015-07-10 00:00:00

  • Regional effect of estradiol on rat caudate-putamen dopamine receptors: lateral-medial differences.

    abstract::The effect of a chronic 17 beta-estradiol (10 micrograms, b.i.d.) treatment of 2 weeks to ovariectomized rats was investigated on lateral and medial caudate-putamen dopamine receptors. Dopamine D2 receptors were assayed with [3H]spiperone binding to caudate-putamen homogenates or by autoradiography of forebrain sectio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(87)90048-6

    authors: Falardeau P,Di Paolo T

    更新日期:1987-02-10 00:00:00

  • Are serotonin 3A and 3B receptor genes associated with suicidal behavior in schizophrenia subjects?

    abstract::Suicide is a major contributor to the morbidity and mortality of schizophrenia, accounting for approximately 10% of deaths in these patients. Genetic factors have been reported to modulate the risk for suicide, although the precise mechanism and magnitude of the genetic contribution are unknown. Further, suicide attem...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.11.079

    authors: Souza RP,De Luca V,Manchia M,Kennedy JL

    更新日期:2011-02-11 00:00:00

  • Elevated expression of neurotrophin-3 mRNA in sensory nerve of streptozotocin-diabetic rats.

    abstract::Decreased expression of NT-3 mRNA in the sciatic nerve and leg muscles of streptozotocin (STZ)-diabetic rats has been associated with the pathogenesis of diabetic neuropathy. The aim of this study was to determine whether STZ-induced diabetes also affects the expression of NT-3 mRNA in the central and peripheral proje...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00124-x

    authors: Cai F,Tomlinson DR,Fernyhough P

    更新日期:1999-03-26 00:00:00

  • Increased expression of metabotropic glutamate receptor subtype 1 on spinothalamic tract neurons following spinal cord injury in the rat.

    abstract::Spinal cord injury (SCI) leads to an increase in metabotropic glutamate receptor subtype 1 (mGluR1) immunoreactivity in the peri-lesion area. The increased expression of mGluR1 parallels the development of thermal hyperalgesia and mechanical allodynia and has been suggested to contribute to the development and mainten...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02551-4

    authors: Mills CD,Hulsebosch CE

    更新日期:2002-02-15 00:00:00

  • Cardiovascular regulation during upright standing behavior in conscious rats.

    abstract::Although rats often show an upright standing behavior the cardiovascular response during the behavior has not yet been fully clarified. In this study we quantified the activity of upright standing behavior in rats using infrared beam detectors and measured cardiovascular variables during the behavior. Rats demonstrate...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.10.087

    authors: Waki H,Katahira K,Yamasaki M,Katsuda S,Shimizu T,Maeda M

    更新日期:2009-01-02 00:00:00

  • Cerebrospinal fluid vasopressin and oxytocin: evidence for an osmotic response.

    abstract::A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion period. High sodium...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(82)90329-9

    authors: Barnard RR Jr,Morris M

    更新日期:1982-04-26 00:00:00

  • The changes in the activity of pudendal motoneurons in relation to reflex micturition evoked in decerebrate cats.

    abstract::Reflex micturition was evoked in both non-immobilized (n = 5) and immobilized (n = 5) decerebrate cats by filling the bladder with physiological saline. Intracellular recordings were made from pudendal motoneurons (PU-MNs; n = 14) throughout the periods of before, during and after reflex micturition. The changes in th...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90430-f

    authors: Shimoda N,Takakusaki K,Nishizawa O,Tsuchida S,Mori S

    更新日期:1992-02-03 00:00:00

  • Impaired SynGAP expression and long-term spatial learning and memory in hippocampal CA1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of A68930.

    abstract::Hypoxic encephalopathy is a common cause of neonatal seizures and long-term neurological cognitive deficits. In rats at postnatal days 10-12 (P10-P12), global hypoxia induced spontaneous seizures and chronic brain injury, mimicking clinical aspects of neonatal hypoxia. Synaptic Ras-GTPase activating protein (SynGAP) h...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.08.044

    authors: Yang SN,Huang CB,Yang CH,Lai MC,Chen WF,Wang CL,Wu CL,Huang LT

    更新日期:2004-11-16 00:00:00

  • The influence of semantic priming on event-related potentials to painful laser-heat stimuli in humans.

    abstract::In this study we investigated the effects of different semantic primes on the processing of painful stimuli. For prime stimuli, descriptors of three categories were used: somatosensory pain-related, affective pain-related, and neutral adjectives. While subjects (n=10) processed these primes, a painful laser-heat stimu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)00957-5

    authors: Dillmann J,Miltner WH,Weiss T

    更新日期:2000-04-21 00:00:00

  • Adaptive response to stress of acute myocardial infarction leads to apoptosis of retinal cells of rats.

    abstract::Evidence indicates that adaptive responses to systemic stress occur in retina, as indicated by the changes in sympathetic and sensory afferent neurotransmitters in the retina when under stressful stimulation, such as acute myocardial infarction. The aim of this study was to investigate the potential association of the...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.10.006

    authors: Yang JH,Xie LS,Guo Z

    更新日期:2011-01-03 00:00:00

  • Down regulation of TRPC1 by shRNA reduces mechanosensitivity in mouse dorsal root ganglion neurons in vitro.

    abstract::Mechanosensitivity is a crucial but poorly understood property of the sensory nervous system. Transient receptor potential (TRP) channels, which have been found to be responsible for the detection of other sensory stimuli such as temperature and pungent chemicals, have been suggested to also recognize stretch or press...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.03.082

    authors: Staaf S,Maxvall I,Lind U,Husmark J,Mattsson JP,Ernfors P,Pierrou S

    更新日期:2009-06-19 00:00:00

  • (RS)-alpha-Methyl-4-carboxyphenylglycine inhibits long-term potentiation only following the application of low frequency stimulation in the rat dentate gyrus in vitro.

    abstract::The effect of the metabotropic glutamate receptor (mGluR) antagonist (RS)-alpha-methyl-4-carboxyphenylglycine (MCPG) was investigated on the induction of long-term potentiation (LTP) of alpha-amino-3-hydroxy-5- methyl-4-isoxazoleproprionate receptor-mediated excitatory postsynaptic currents (epscs) recorded from denta...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11937-r

    authors: Wang Y,Rowan MJ,Anwyl R

    更新日期:1995-09-15 00:00:00

  • Short biotinylated oligonucleotides bind non-specifically to senile plaques of Alzheimer's disease.

    abstract::We have used in situ hybridization with biotinylated oligonucleotide (antisense) probes and streptavidin-biotinylated alkaline phosphatase method to detect the amount of amyloid beta-protein mRNA in the paraffin-embedded and formalin-fixed brain samples of patients affected by Alzheimer's disease and those of non-affe...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90234-k

    authors: Syrjänen S,Heinonen O,Miettinen R,Paljärvi L,Syrjänen K,Riekkinen P

    更新日期:1991-09-02 00:00:00

  • Inhibition by locus coeruleus on the baroreceptor reflex response in the rat.

    abstract::We evaluated the modulation of baroreceptor reflex (BRR) response by locus coeruleus (LC) in adult, male Sprague-Dawley rats anesthetized with urethane (1.5 g/kg, i.p.). Under an electrical stimulation condition that did not appreciably alter the basal systemic arterial pressure and heart rate, the LC significantly su...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90755-v

    authors: Chan JY,Jang SF,Chan SH

    更新日期:1992-09-14 00:00:00

  • Enhancing the anterograde movement of HRP to label sparse neuronal projections.

    abstract::By combining techniques designed to increase the amount of horseradish peroxidase (HRP) available for transport and to improve the sensitivity of the reaction for detecting HRP, we have produced an anterograde HRP technique suitable for labeling sparse efferent projections. The efficacy of this light, microscopic tech...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(79)91476-9

    authors: West JR,Black AC Jr

    更新日期:1979-04-01 00:00:00

  • A property of face representation at the categorical level.

    abstract::Face processing is unique to human beings and is likely to have special neuronal properties. We studied one of these properties, categorical representation of the face in perception processing (perception) and in memory recall processing (imagery), using the face and building stimuli. The same building-selective areas...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.09.053

    authors: Sung YW,Ogawa S

    更新日期:2008-12-19 00:00:00

  • Neonatal enucleation during a critical period reduces the precision of cortico-cortical projections in visual cortex.

    abstract::Previous studies have reported that intrahemispheric connections between area 17 (V1, striate cortex) and other cortical visual areas are not point-to-point, but instead have some degree of convergence and divergence. Many pathological conditions can interfere with the normal development of patterns of cortico-cortica...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.07.005

    authors: Bock AS,Olavarria JF

    更新日期:2011-09-01 00:00:00

  • NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase.

    abstract::Previous studies have showed that SIN-1, a nitric oxide (NO) donor, injected into the dorsolateral column of the periaqueductal gray (dlPAG) induces flight reactions. This drug, however, can also produce peroxynitrite, which may interfere in this effect. In addition, it is also unknown if this effect is mediated by lo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.05.009

    authors: Braga AA,Aguiar DC,Guimarães FS

    更新日期:2009-08-07 00:00:00

  • Mortality in gerbils with repetitive ischemia: CGSGS-19755/hypothermia therapy.

    abstract::Repetitive ischemia causes more severe damage than a single insult of comparable duration. Gerbils were followed for 1 month postrepetitive ischemia and 100% mortality was demonstrated in the unprotected ischemia group by 12 days postischemia. Significant protection against mortality due to repetitive ischemia was off...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90257-7

    authors: McCrea S,Shuaib A,Wishart T,Ijaz S

    更新日期:1994-03-28 00:00:00

  • Melatonin supplementation delays the decline of adult hippocampal neurogenesis during normal aging of mice.

    abstract::Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.09.045

    authors: Ramírez-Rodríguez G,Vega-Rivera NM,Benítez-King G,Castro-García M,Ortíz-López L

    更新日期:2012-11-14 00:00:00

  • The potential effects of transcranial direct current stimulation (tDCS) on language functioning: Combining neuromodulation and behavioral intervention in aphasia.

    abstract::Aphasia is a highly disabling language disorder usually caused by a left stroke brain damage. Even if traditional language therapies have been proved to induce an adequate clinical recovery, a large percentage of patients are left with chronic deficits at 6 months post-stroke. Therefore, new strategies to common speec...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2017.12.057

    authors: Marangolo P

    更新日期:2020-02-06 00:00:00

  • Ovarian hormones prevent methamphetamine-induced anxiety-related behaviors and neuronal damage in ovariectomized rats.

    abstract::Methamphetamine (METH) may cause long‒lasting neurotoxic effects and cognitive impairment. On the other hand, the ovarian hormones estrogen and progesterone have neuroprotective effects. In the current study, we aimed to examine the effects of estrogen and progesterone on anxiety‒like behavior and neuronal damage in M...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2021.135652

    authors: Ghazvini H,Tirgar F,Khodamoradi M,Akbarnejad Z,Rafaiee R,Seyedhosseini Tamijani SM,Asadi-Shekaari M,Esmaeilpour K,Sheibani V

    更新日期:2021-01-19 00:00:00

  • Regional homogeneity of the resting-state brain activity correlates with individual intelligence.

    abstract::Resting-state functional magnetic resonance imaging has confirmed that the strengths of the long distance functional connectivity between different brain areas are correlated with individual differences in intelligence. However, the association between the local connectivity within a specific brain region and intellig...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.11.046

    authors: Wang L,Song M,Jiang T,Zhang Y,Yu C

    更新日期:2011-01-25 00:00:00