Cerebrospinal fluid vasopressin and oxytocin: evidence for an osmotic response.

abstract：:NMDA receptors play important roles in brain formation by taking part in synaptogenesis and apoptosis. In the present study, the expression of NMDA receptors was analyzed in a neural stem cell line, MSP-1, which lacks p53. p53 is a transcription factor involved in excitotoxic neuronal apoptosis. It is quite likely tha...

journal_title：Neuroscience letters

authors： Yamada K,Hisatsune T,Uchino S,Nakamura T,Kudo Y,Kaminogawa S

更新日期：1999-04-02 00:00:00

abstract：:Transient potassium currents of the A type are thought to be important in a number of physiological processes of excitable cells, including spike repolarization and synaptic integration. This functional diversity may reflect the contribution of distinct subtypes of A channel to cellular behavior. Using the whole-cell ...

journal_title：Neuroscience letters

authors： Surmeier DJ,Bargas J,Kitai ST

更新日期：1989-09-11 00:00:00

abstract：:Direct exposure of rats to tobacco smoke induces antinociception. We presently investigated if this antinociception is mediated via nicotinic and/or mu-opioid receptors. Adult male rats were surgically implanted with Alzet osmotic minipumps that delivered either saline (control), the nicotinic antagonist mecamylamine,...

journal_title：Neuroscience letters

authors： Simons CT,Cuellar JM,Moore JA,Pinkerton KE,Uyeminami D,Carstens MI,Carstens E

更新日期：2005-12-02 00:00:00

abstract：:Tyrosine phosphorylation is an important means for regulating post-ischemic signal transduction. In this article, brain ischemia was induced by four-vessel occlusion, and the effect of ischemia/reperfusion on proline-rich tyrosine kinase 2 (Pyk2) was studied. Tyrosine phosphorylation of Pyk2 in Sprague-Dawley rat hipp...

journal_title：Neuroscience letters

authors： Liu Y,Zhang GY,Hou XY,Xu TL

更新日期：2003-09-18 00:00:00

abstract：:The formation of the beta pleated configuration of the amyloid peptide fragment 25-35 in aqueous solution, has been studied using thioflavin-T fluorescence as an indicator of such folding. Both phosphate and adenosine triphosphate (ATP) enhance the formation of aggregated beta-sheets. This phosphate-induced aggregatio...

journal_title：Neuroscience letters

authors： Bondy SC,Truong A

更新日期：1999-05-21 00:00:00

abstract：:Rim is a multi-domain, active zone protein that regulates exocytosis and is implicated in vesicle priming and presynaptic plasticity. We recently demonstrated that synaptic defects associated with loss of Caenorhabditis elegans Rim (termed UNC-10) are accompanied by a reduction in docked vesicles adjacent to the presy...

journal_title：Neuroscience letters

authors： Gracheva EO,Hadwiger G,Nonet ML,Richmond JE

更新日期：2008-10-24 00:00:00

abstract：:Hypoxic preconditioning (HP) is a novel strategy to make stem cells resistant to the ischemic environment they encounter after transplantation into injured tissue; this strategy improves survival of both the transplanted cells and the host cells at the injury site. Using both in vitro and in vivo injury models, we con...

journal_title：Neuroscience letters

authors： Oh JS,Ha Y,An SS,Khan M,Pennant WA,Kim HJ,Yoon DH,Lee M,Kim KN

更新日期：2010-03-26 00:00:00

abstract：:The involvement of protein kinases A and C in the induction of low frequency stimulation-induced long-term depression (LTD) in the medial perforant path of the dentate gyrus in vitro has been studied using the selective PKA inhibitors H-89 and KT 5720 and PKC inhibitors Bisindolylmaleimide and Ro-31-8220. The PKC inhi...

journal_title：Neuroscience letters

authors： Huang LQ,Rowan MJ,Anwyl R

更新日期：1999-10-22 00:00:00

abstract：:Propofol has been demonstrated as a drug of abuse in humans. Our previous study indicated that dexamethasone, a potent agonist of glucocorticoid receptor (GR), inhibited propofol-maintained rat self-administration behaviors by systematic injection. However, the direct effect of GR in the nucleus accumbens (NAc) on pro...

journal_title：Neuroscience letters

authors： Wu B,Lin W,Wang H,Abdullah T,Wang B,Su Y,Ge RS,Lian Q

更新日期：2018-01-01 00:00:00

abstract：:The present study is designed to screen the effect of syringin, an active principle purified from the rhizome and root parts of Eleutherococcus senticosus (Araliaceae), on the plasma glucose and investigate the possible mechanisms. Plasma glucose decreased in a dose-dependent manner 60 min after intravenous injection ...

journal_title：Neuroscience letters

authors： Liu KY,Wu YC,Liu IM,Yu WC,Cheng JT

更新日期：2008-03-28 00:00:00

abstract：:The present study was performed to explore the role of galanin in nociceptive modulation in anterior cingulate cortex (ACC) of rats with acute inflammation, and the changes in galanin and galanin receptor 2 (Gal R2) expressions in rats with acute inflammation. Intra-ACC injection of galanin induced antinociception in ...

journal_title：Neuroscience letters

authors： Zhang ML,Fu FH,Yu LC

更新日期：2017-01-18 00:00:00

abstract：:In rodents the vomeronasal system plays an important role in modulating the hypothalamic control of gonadotropin secretion. It is accepted that the anatomical pathways by which the vomeronasal organ influences the neuroendocrine aspects of the reproductive behavior involves a polysynaptic system, including the accesso...

journal_title：Neuroscience letters

authors： Larriva-Sahd J,Rondán A,Orozco-Estévez H,Sánchez-Robles MR

更新日期：1993-11-26 00:00:00

abstract：:Magnetic resonance imaging was used to investigate the relation between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and volumetric measurements for the medial temporal lobe structures (amygdala, hippocampus, and parahippocampal gyrus) and prefrontal sub-regions (the superior frontal gyrus, middl...

journal_title：Neuroscience letters

authors： Takahashi T,Suzuki M,Tsunoda M,Kawamura Y,Takahashi N,Tsuneki H,Kawasaki Y,Zhou SY,Kobayashi S,Sasaoka T,Seto H,Kurachi M,Ozaki N

更新日期：2008-04-11 00:00:00

abstract：:We performed an electron microscopic study in layers II-III of S-1 in rats, using postembedding immunogold histochemistry to compare the synaptic distribution of N-methyl D-aspartate (NMDA) receptors (assessed with an antibody for the NMDAR1 subunit) with that of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (A...

journal_title：Neuroscience letters

authors： Kharazia VN,Weinberg RJ

更新日期：1997-11-28 00:00:00

abstract：:Anatomical relationships of hypothalamic cocaine- and amphetamine-regulated transcript (CART) with other hypothalamic neuropeptides were examined by using in situ hybridization histochemistry and immunohistochemistry. CART mRNA was found in various regions in rat hypothalamus, including the periventricular nucleus, pa...

journal_title：Neuroscience letters

authors： Li HY,Hwang HW,Hu YH

更新日期：2002-05-03 00:00:00

abstract：:Cyclin-dependent kinase 5 (cdk5) is a homologue of cell division cycle 2 (cdc2)-like protein kinase. It is mainly expressed in neurons, and supposed to be involved in the dynamic change of neurocytoskeleton structure seen in the brain after ischemia. In the present study, we investigated immunoreactivity for cdk5 and ...

journal_title：Neuroscience letters

authors： Hayashi T,Warita H,Abe K,Itoyama Y

更新日期：1999-04-09 00:00:00

abstract：:Abnormal myelin gene expression in the central nervous system (CNS) is associated with many mental illnesses, including psychiatric disorders and drug addiction. We have previously shown that prenatal exposure to nicotine, the major psychoactive component in cigarette smoke, alters myelin gene expression in the CNS of...

journal_title：Neuroscience letters

authors： Cao J,Dwyer JB,Gautier NM,Leslie FM,Li MD

更新日期：2013-10-11 00:00:00

abstract：:The action of some cholinergic drugs has been studied on the field potentials evoked by orthodromic stimulation of the lateral olfactory tract (LOT) in guinea-pig olfactory cortex slices maintained in vitro. A reversible depression of the electrically evoked surface-negative field potential (N-wave) was seen following...

journal_title：Neuroscience letters

authors： Williams SH,Constanti A,Brown DA

更新日期：1985-05-23 00:00:00

abstract：:The mesencephalic trigeminal nucleus contains cell bodies of primary somatic sensory neurons that innervate the head region. The neurons resemble dorsal root ganglion cells but a striking difference is the presence of synaptic boutons in the nucleus. The present report demonstrates with anterograde tracers, the existe...

journal_title：Neuroscience letters

authors： Buisseret-Delmas C,Pinganaud G,Compoint C,Buisseret P

更新日期：1997-07-04 00:00:00

abstract：:Nitric oxide (NO) exerts cytotoxic effects on various cells including neuronal cells. Glial NO production, mediated via induction of inducible NO synthase (iNOS), enhances neurotoxicity associated with the N-methyl-D-aspartate (NMDA) receptor. The present study examined whether nicotinamide, an inhibitor of poly (ADP-...

journal_title：Neuroscience letters

authors： Fujimura M,Tominaga T,Yoshimoto T

更新日期：1997-06-06 00:00:00

abstract：:Amyotrophic Lateral Sclerosis (ALS) is a devastating and fatal neurodegenerative disease affecting approximately 30,000 individuals in the United States. The average age of onset is 55 years and progression of the disease is rapid with most patients dying of respiratory failure within 3-5 years. Currently available th...

journal_title：Neuroscience letters

authors： St Martin JL,Wang L,Kaprielian Z

更新日期：2020-01-18 00:00:00

abstract：:A growing body of evidence has demonstrated a role for group II metabotropic glutamate receptors (mGluRs) in the reinforcing effects of cocaine. These receptors are important given their location in limbic-related areas, and their ability to control the release of glutamate and other neurotransmitters. They are also p...

journal_title：Neuroscience letters

authors： Beveridge TJ,Smith HR,Nader MA,Porrino LJ

更新日期：2011-05-27 00:00:00

abstract：:Previous studies have shown significant increases in regional cerebral metabolic rate for glucose (rCMRgl) in 14 of 28 investigated brain structures in rats exposed to 1-h oxygen at 2 atmosphere absolute (ATA O2). Continuous 4-h exposure to 2 ATA O2 resulted in significant increases only in superior olivary nucleus an...

journal_title：Neuroscience letters

authors： Torbati D,Lo P,Lambertsen CJ

更新日期：1984-09-07 00:00:00

abstract：:We investigated the mRNA expression of the various complement components in cultured mouse microglia and astrocytes by the reverse transcription and polymerase chain reaction. C1q, C2, C3, and C4 mRNAs were detected in microglial cultures. C3 and C4 mRNAs were found in astrocyte cultures. Microglia showed enhanced exp...

journal_title：Neuroscience letters

authors： Haga S,Aizawa T,Ishii T,Ikeda K

更新日期：1996-10-04 00:00:00

abstract：:The highest prevalence rate of spinocerebellar ataxia type 6 (SCA6) in the worldwide population is in the Chugoku and Kansai areas of Western Japan, but the reason of this geographic characteristics is unclear. We investigated the predisposing haplotypes and their geographic distribution. Genotyping of five microsatel...

journal_title：Neuroscience letters

authors： Terasawa H,Oda M,Morino H,Miyachi T,Izumi Y,Maruyama H,Matsumoto M,Kawakami H

更新日期：2004-03-25 00:00:00

abstract：:Hibernation in mammals is a whole-body phenotype that involves profound reductions in oxygen consumption, metabolic reactions, core body temperature, neural activity and heart rate. An important aspect of mammalian hibernation is the ability to reverse this state of hypothermic torpor by rewarming and subsequent arous...

journal_title：Neuroscience letters

authors： Oliver SR,Anderson KJ,Hunstiger MM,Andrews MT

更新日期：2019-03-23 00:00:00

abstract：:The effects of Ga-Al-As diode laser (830 nm, 16.2 mW) irradiation on the distal portion of the processes of cultured murine dorsal root ganglion (DRG) neurons associated with C-fibers were studied by patch-clamp whole-cell recording of membrane potentials at the cell body. The chemical as well as laser light stimulati...

journal_title：Neuroscience letters

authors： Jimbo K,Noda K,Suzuki K,Yoda K

更新日期：1998-01-09 00:00:00

abstract：:In the present study we have investigated the effects of nicotine, capsaicin, potassium, glutamate and aspartate on release of calcitonin gene-related peptide (CGRP)-like immunoreactivity (-LI) from guinea-pig dorsal root ganglion (DRG) cultures. In addition the possible influence of Ruthenium red (RR), neuropeptide Y...

journal_title：Neuroscience letters

authors： Franco-Cereceda A,Rydh M,Dalsgaard CJ

更新日期：1992-03-16 00:00:00

abstract：:Electrophysiological and anatomic studies suggest that the amygdala regulates gastrointestinal motility and gastric acid secretion via projections to the dorsal vagal complex. The topography of these projections is poorly understood. Here, these projections were investigated by injecting anterograde tracer, Phaseolus ...

journal_title：Neuroscience letters

authors： Liubashina O,Jolkkonen E,Pitkänen A

更新日期：2000-09-15 00:00:00

abstract：:The cyclic AMP/protein kinase A signaling pathway is thought to be involved in neural differentiation of mesenchymal stem cells. In the present study, we examined the involvement of β-adrenoceptor signaling on the differentiation of mouse induced pluripotent stem (iPS) cells into neural progenitor cells. Mouse iPS cel...

journal_title：Neuroscience letters

authors： Ishizuka T,Goshima H,Ozawa A,Watanabe Y

更新日期：2012-09-06 00:00:00