Two types of A-current differing in voltage-dependence are expressed by neurons of the rat neostriatum.

Abstract:

:Transient potassium currents of the A type are thought to be important in a number of physiological processes of excitable cells, including spike repolarization and synaptic integration. This functional diversity may reflect the contribution of distinct subtypes of A channel to cellular behavior. Using the whole-cell variant of the patch clamp technique, we have found that two types of A-current are expressed in rat neostriatal neurons, one that is similar to previous descriptions in mammals and a second that is activated at considerably more depolarized potentials.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Surmeier DJ,Bargas J,Kitai ST

doi

10.1016/0304-3940(89)90122-5

subject

Has Abstract

pub_date

1989-09-11 00:00:00

pages

331-7

issue

3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(89)90122-5

journal_volume

103

pub_type

杂志文章
  • Organum vasculosum lamina terminalis: innervation by serotonin neurons of the midbrain raphe.

    abstract::The monoamine innervation of the organum vasculosum lamina terminalis (OVLT) was studied using fluorescence histochemistry and the autoradiographic tracing method. Fluorescence histochemistry demonstrates serotonin terminals in close proximity to the capillary plexus of the OVLT, in the same region where the apparent ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(77)90082-9

    authors: Moore RY

    更新日期:1977-08-01 00:00:00

  • Changes in dural thickness reflect changes in intracranial pressure in dogs.

    abstract::The thickness of the dura mater was obtained from ultrasound probes on the skull and fast Fourier transform-Cepstrum through a probability process at various intracranial pressures (ICP), measured with pressure transducers, in 12 anesthetized dogs. There was a constant relationship between changes in thickness (micron...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11949-w

    authors: Kuchiwaki H,Inao S,Ishii N,Ogura Y,Sakuma N

    更新日期:1995-09-22 00:00:00

  • Decreased cortical levels of astrocytic glutamate transport protein GLT-1 in a rat model of posttraumatic epilepsy.

    abstract::The extracellular homeostasis of glutamate in the brain is maintained by the efficient uptake into astroglial cells. The high extracellular glutamate levels seen during seizures are therefore probably a result of both an increased synaptic release and a deranged glutamate uptake. In this study we used immuno-blotting ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01284-2

    authors: Samuelsson C,Kumlien E,Flink R,Lindholm D,Ronne-Engström E

    更新日期:2000-08-11 00:00:00

  • Inhibition of nicotine-induced hippocampal norepinephrine release in rats by alpha-conotoxins MII and AuIB microinjected into the locus coeruleus.

    abstract::Hippocampal norepinephrine (NE) is secreted by neurons projecting from the locus coeruleus (LC) to the hippocampus; LC nicotinic receptors (NAchRs) are involved in the effects of systemic nicotine on this pathway. To clarify the NAchR subtypes, NAchR antagonists, termed alpha-conotoxins, were microinjected into the LC...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00293-1

    authors: Fu Y,Matta SG,McIntosh JM,Sharp BM

    更新日期:1999-05-07 00:00:00

  • Amphetamine and extinction of cued fear.

    abstract::Much research is focused on developing novel drugs to improve memory. In particular, psychostimulants have been shown to enhance memory and have a long history of safe use in humans. In prior work, we have shown that very low doses of amphetamine administered before training on a Pavlovian fear-conditioning task can d...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.10.049

    authors: Carmack SA,Wood SC,Anagnostaras SG

    更新日期:2010-01-01 00:00:00

  • Removal of retinal input fails to elicit isthmo-tectal sprouting in the frog.

    abstract::The retina and nucleus isthmi both project in laminar fashion to the superficial layers of the frog's tectum. In order to determine whether isthmo-tectal axons show collateral sprouting after retinotectal input is removed, we injected [3H] proline into the nucleus isthmi and measured the volume of the crossed isthmo-t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(81)90252-4

    authors: Udin SB,Gruberg ER

    更新日期:1981-12-11 00:00:00

  • Astroglial cells inhibit the increasing permeability of brain endothelial cell monolayer following hypoxia/reoxygenation.

    abstract::Blood-brain barrier (BBB) is known to be structured with astroglial cells (AGs) and brain endothelial cells (BECs), and it has been proposed that these cells play different roles in the BBB. We cultivated AGs and BECs from infant rats (2-week-old), and these cells were cultured on the opposing side of collagen membran...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(96)12555-6

    authors: Kondo T,Kinouchi H,Kawase M,Yoshimoto T

    更新日期:1996-04-19 00:00:00

  • Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells.

    abstract::The effect of K-252a, a new alkaloid-like kinase inhibitor from the culture broth of Nocardiopsis sp., on the action of nerve growth factor on normal nerve cells was examined. Nerve cells were isolated from the dorsal root ganglia of chick embryo by trituration without using digesting enzymes, and were seeded on colla...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90137-1

    authors: Matsuda Y,Fukuda J

    更新日期:1988-04-22 00:00:00

  • The distribution and origin of axon terminals with NADPH diaphorase activity in the nucleus of the solitary tract of the rat.

    abstract::The distribution and origin of axon terminals containing nitric oxide synthase (NOS) were examined in the nucleus of the solitary tract (NST) of the rat by NADPH diaphorase histochemistry combined with nodose ganglionectomy. Axon terminals with NADPH diaphorase activity were densely distributed in the middle and cauda...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90607-6

    authors: Lü Y,Ding YQ,Qin BZ,Li JS

    更新日期:1994-04-25 00:00:00

  • 2-Deoxy-d-glucose protects neural progenitor cells against oxidative stress through the activation of AMP-activated protein kinase.

    abstract::2-Deoxy-d-glucose (2DG) is an analog of glucose that is effectively taken up by cells competing with normal glucose but cannot be further utilized to produce energy. It was previously reported that 2DG can mimic the beneficial effects of dietary restriction in experimental models of neurodegenerative disorders and can...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.11.007

    authors: Park M,Song KS,Kim HK,Park YJ,Kim HS,Bae MI,Lee J

    更新日期:2009-01-16 00:00:00

  • Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases.

    abstract::Nitric oxide (NO) from endothelial or neuronal NO synthases (eNOS or nNOS) may contribute both to the cerebrovascular responses to oxygen and potentially to the peroxynitrite-mediated toxic effects of hyperbaric oxygen (HBO(2)) on the central nervous system (CNS O(2) toxicity). In mice lacking eNOS or nNOS (-/-), regi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00432-4

    authors: Demchenko IT,Atochin DN,Boso AE,Astern J,Huang PL,Piantadosi CA

    更新日期:2003-06-19 00:00:00

  • Multiplicity of opiate receptors in different species.

    abstract::Three populations of opiate binding sites (mu, delta and kappa) could be distinguished by displacement studies with the mu-agonist (D)-Ala2-MePhe4-Glyol5-enkephalin and the kappa-agonist [3H](-)-bremazocine in brain membranes of different species. Whereas brain membranes from pig or guinea-pig and human cortical membr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(82)90417-7

    authors: Maurer R

    更新日期:1982-06-30 00:00:00

  • Beta rebound after different types of motor imagery in man.

    abstract::We investigated the behavior of short-lasting beta bursts (beta rebound, beta ERS) induced after imagination of hand, foot or tongue movement. Nine able-bodied subjects were asked to imagine one type of movement following the presentation of a visual cue stimulus. EEG was recorded from 60 closely spaced electrodes pla...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.12.034

    authors: Pfurtscheller G,Neuper C,Brunner C,da Silva FL

    更新日期:2005-04-22 00:00:00

  • Variability, regularity and coupling measures distinguish PD tremor from voluntary 5Hz tremor.

    abstract::A characteristic of Parkinson's disease (PD) is the development of tremor within the 4-6Hz range. One method used to better understand pathological tremor is to compare the responses to tremor-type actions generated intentionally in healthy adults. This study was designed to investigate the similarities and difference...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.11.040

    authors: Morrison S,Cortes N,Newell KM,Silburn PA,Kerr G

    更新日期:2013-02-08 00:00:00

  • Effects of 60-GHz millimeter waves on neurite outgrowth in PC12 cells using high-content screening.

    abstract::Technologies for wireless telecommunication systems using millimeter waves (MMW) will be widely deployed in the near future. Forthcoming applications in this band, especially around 60GHz, are mainly developed for high data-rate local and body-centric telecommunications. At those frequencies, electromagnetic radiation...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.02.038

    authors: Haas AJ,Le Page Y,Zhadobov M,Sauleau R,Le Dréan Y

    更新日期:2016-04-08 00:00:00

  • Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression.

    abstract::Basal serotonin (5-HT) release, measured in the presence of imipramine, was significantly reduced in slices of hippocampus, n. accumbens and frontal cortex from rats subjected to forced swim test and chronic isolation. Only in the hippocampus, in the two animal models of depression, K-stimulated release was increased....

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90584-8

    authors: Jaffe EH,De Frias V,Ibarra C

    更新日期:1993-11-12 00:00:00

  • The effect of age on muscarinic receptor transcripts in rat brain.

    abstract::The expression of five muscarinic receptor mRNAs (m1, m2, m3, m4, m5) was examined in neostriatum, hippocampus and frontal cortex of 3, 18, and 33 month old rats. Transcripts for ml (3.0 kb), m2 (6.2 kb), m3 (4.5 kb) and m4 (3.3 kb) were detected in all brain regions studied. A 6.0 kb transcript for the m5 muscarinic ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90022-1

    authors: Lee HJ,Clagett-Dame M,Heideman W,Weiler MS

    更新日期:1994-06-20 00:00:00

  • Cortical and medullary somatosensory projections to the cochlear nuclear complex in the hedgehog tenrec.

    abstract::Various tracer substances were injected into the spinal cord, the dorsal column nuclei, the trigeminal nuclear complex and the somatosensory cortex in Madagascan hedgehog tenrecs. With the exception of the cases injected exclusively into the spinal cord all injections gave rise to sparse, but distinct anterograde proj...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(96)13305-x

    authors: Wolff A,Künzle H

    更新日期:1997-01-17 00:00:00

  • Calyculin A blocks bovine chromaffin cell calcium channels independently of phosphatase inhibition.

    abstract::The specific phosphatase inhibitor, Calyculin-A (CL-A), decreases high-K stimulated catecholamine secretion in bovine chromaffin cells. This effect can be split into two components: one needs long exposures to the drug to be elicited, and is sensitive to the protein kinase-inhibitor K252a; the other is observed after ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90288-7

    authors: Gutiérrez LM,Viniegra S,Quintanar JL,Reig JA,Sala F

    更新日期:1994-08-29 00:00:00

  • DNA versus RNA oxidation in Parkinson's disease: Which is more important?

    abstract:BACKROUND:8-hydroxy-2 deoxyguanosine (8-OHdG) and the 8-hydroxyguanosine (8-OHG) are the most widely used biomarkers of nucleoside oxidation affecting DNA and RNA and are considered reliable markers of oxidative stress. Increased levels of these markers are found in the various biological fluids of patients with neurod...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.09.048

    authors: Gmitterová K,Gawinecka J,Heinemann U,Valkovič P,Zerr I

    更新日期:2018-01-01 00:00:00

  • Pharmacological screening of a new alpha-2 adrenergic receptor agonist, mafedine, in zebrafish.

    abstract::Pharmacological agents acting at alpha-2 adrenergic receptors are widely used in physiology and neuroscience research. Mounting evidence of their potential utility in clinical and experimental psychopharmacology, necessitates new models and novel model organisms for their screening. Here, we characterize behavioral ef...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2019.03.001

    authors: Sysoev YI,Meshalkina DA,Petrov DV,Okovityi SV,Musienko PE,Kalueff AV

    更新日期:2019-05-14 00:00:00

  • Dyslexics show a deviant lateralization of attentional control: a brain potential study.

    abstract::The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.10.072

    authors: Wijers AA,Been PH,Romkes KS

    更新日期:2005-02-10 00:00:00

  • Circadian rhythm of nitric oxide production in the dorsal region of the suprachiasmatic nucleus in rats.

    abstract::Extracellular concentration of nitrite (NO2-), an oxidized product of nitric oxide (NO), was measured consecutively in the dorsal region of the rat suprachiasmatic nucleus (SCN) by means of in vivo microdialysis. The NO2- concentrations in the dialysates showed robust circadian rhythm under a 12:12 h light/dark cycle ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01744-x

    authors: Mitome M,Shirakawa T,Oshima S,Nakamura W,Oguchi H

    更新日期:2001-05-11 00:00:00

  • Visualisation of catecholamine-fluorescent nerve cell bodies in the rat brain after colchicine treatment.

    abstract::Central administration of colchicine causes accumulation of catecholamines in nerve cell bodies and enhances their visualisation in the rat brain by the formaldehyde-glutaraldehyde (FAGLU) histofluorescence method. The detection of catecholamine-containing nerve cells by the FAGLU method was considerably improved in r...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90176-9

    authors: Howe PR,Rogers PF,Blessing WW

    更新日期:1984-12-21 00:00:00

  • Deficits of [3H]D-aspartate binding to glutamate uptake sites in striatal and accumbens tissue in patients with schizophrenia.

    abstract::The hypothesis involving glutamate in the neuropathology of schizophrenia has attracted great interest. Several studies report dysfunctions in glutamatergic systems, including alterations in kainate and N-methyl-D-aspartate (NMDA) receptors in various areas, as well as changes in the number of glutamate uptake sites. ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00563-6

    authors: Aparicio-Legarza MI,Cutts AJ,Davis B,Reynolds GP

    更新日期:1997-08-22 00:00:00

  • A functional subdivision of the circadian clock is revealed by differential effects of melatonin administration.

    abstract::The biological clock of the suprachiasmatic nuclei drives numerous physiological and behavioural circadian rhythms. In this study, we addressed the question as to whether different components of the clock may control separately various circadian functions. Using the rat transpineal microdialysis tool, we analysed the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.11.007

    authors: Tritschler L,Saboureau M,Pévet P,Bothorel B

    更新日期:2006-03-20 00:00:00

  • Evidence against an exclusive role of glutamate in kainic acid neurotoxicity.

    abstract::Transection of the non-glutamatergic septohippocampal fibers 3-5 days prior to intrahippocampal microinjection of 1 microgram kainic acid (KA) or 3 micrograms ibotenic acid (IBO) protect dentate granule cells against KA but not IBO. In the transected animals, a significant reduction of KA-induced behavioral seizures c...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(80)90268-2

    authors: Schwarcz R,Köhler C

    更新日期:1980-10-02 00:00:00

  • The peripheral role of group I metabotropic glutamate receptors on nociceptive behaviors in rats with knee joint inflammation.

    abstract::We examined whether the mGluR1 and mGluR5 were involved in development and maintenance of behavioral signs of non-evoked pain and secondary mechanical hyperalgesia induced by knee joint inflammation. Selective mGluR1 antagonist, (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA: 50, 100, 200 microM/25 microl, n=10 per gro...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.01.063

    authors: Lee KS,Kim J,Yoon YW,Lee MG,Hong SK,Han HC

    更新日期:2007-04-12 00:00:00

  • The nicotinic alpha subunit MARA1 is necessary for cholinergic evoked calcium transients in Manduca neurons.

    abstract::The functional contribution of cloned subunits to insect nicotinic acetylcholine (ACh) receptors has been difficult to determine using heterologous expression. Instead, in this study we explore the subunit composition of naturally expressed functional receptors in an insect using RNA interference. The nicotinic alpha ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02228-5

    authors: Vermehren A,Qazi S,Trimmer BA

    更新日期:2001-11-09 00:00:00

  • Lack of cross-tolerance between the antinociceptive effect of intrathecal orphanin FQ and morphine in the rat.

    abstract::We assessed whether tolerance develops to the antinociceptive effect of intrathecal (i.t.) orphanin FQ, the endogenous ligand of the orphan opioid-like receptor, and whether there is a cross-tolerance between the antinociceptive effect of i.t. orphanin FQ and the mu opioid receptor agonist morphine. Orphanin FQ admini...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)13401-2

    authors: Hao JX,Wiesenfeld-Hallin Z,Xu XJ

    更新日期:1997-02-14 00:00:00