Abstract:
:Electrophysiological and anatomic studies suggest that the amygdala regulates gastrointestinal motility and gastric acid secretion via projections to the dorsal vagal complex. The topography of these projections is poorly understood. Here, these projections were investigated by injecting anterograde tracer, Phaseolus vulgaris-leucoagglutinin, into the different divisions of the central nucleus of the amygdala in 13 rats. The distribution of immunohistochemically labeled terminals in the different portions of the dorsal vagal complex was analyzed. We found that (1) the dorsal aspect of the medial division of the central nucleus provided moderate projections to the dorsal vagal complex; (2) the heaviest projections terminated in the parvicellular and medial divisions of the nucleus of the solitary tract. These data suggest that via topographically organized projections, the amygdala can modulate the vago-vagal gastrointestinal reflexes in emotional and stressful situations.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Liubashina O,Jolkkonen E,Pitkänen Adoi
10.1016/s0304-3940(00)01392-6keywords:
subject
Has Abstractpub_date
2000-09-15 00:00:00pages
85-8issue
2eissn
0304-3940issn
1872-7972pii
S0304-3940(00)01392-6journal_volume
291pub_type
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