The involvement of L-type calcium channels in heterosynaptic long-term depression in the hippocampus.

abstract：:Turnover rates, as estimated from the accumulation of the intermediates, 3,4-dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) following decarboxylase inhibition, were used to investigate the relationship between central catecholaminergic and serotonergic neurons and the development of hypertension in the ...

journal_title：Neuroscience letters

authors： Shum AY,Chen CS,Hsu SC,Chen CF

更新日期：1987-03-31 00:00:00

abstract：:The present experiment investigated cortical responses of native Italian subjects during reading of short sentences including semantic or morphosyntactic violations. Given the specificity of the Italian language in which the sequencing of words is relatively more free than in English or other languages, we investigate...

journal_title：Neuroscience letters

authors： Angrilli A,Penolazzi B,Vespignani F,De Vincenzi M,Job R,Ciccarelli L,Palomba D,Stegagno L

更新日期：2002-03-29 00:00:00

abstract：:Protein kinase G (PKG) has been implicated in a variety of physiological functions including synaptic plasticity in the brain. This study investigated the involvement of dopamine D3 (D3) receptors in PKG-regulated dopamine release, long-term changes in gene expression and behavioral sensitization after repeated cocain...

journal_title：Neuroscience letters

authors： Lee DK,Oh JH,Yang JH,Youn B,Shim YB,Shim I,Wang JQ,Choe ES

更新日期：2013-04-29 00:00:00

abstract：:Mutations in presenilins are the major cause of early onset familial Alzheimer disease. It has recently been argued that clinical presenilin mutations work as loss-of-function but not toxic gain-of-function. To investigate whether presenilins are involved in the regulation of the distribution of neuronal membrane lipi...

journal_title：Neuroscience letters

authors： Oikawa N,Goto M,Ikeda K,Taguchi R,Yanagisawa K

更新日期：2012-09-06 00:00:00

abstract：:In this study, we examined the involvement of chemokine monocyte chemoattractant protein-1 (MCP-1) in the spinal cord of a rat model of cancer-induced bone pain (CIBP). In this model, CIBP was established by an intramedullary injection of Walker 256 cells into the tibia of rats. We observed a significant increase in e...

journal_title：Neuroscience letters

authors： Hu JH,Zheng XY,Yang JP,Wang LN,Ji FH

更新日期：2012-05-23 00:00:00

abstract：:This study examined the effect of gestational age of rat ventral mesencephalon (VM) on the characteristics of neurospheres generated from this region and on the yield of each cell type after differentiation of these neurospheres. Neurospheres generated from embryonic day (E) 12 and E13 VM had significantly larger diam...

journal_title：Neuroscience letters

authors： O' Keeffe GW,Sullivan AM

更新日期：2005-02-28 00:00:00

abstract：:Recent findings indicated that the excitotoxicity of glutamate analogues was prevented in the mammalian nervous system by N-methyl-D-aspartate (NMDA) antagonists. The neurodegenerative effects of kainic acid, and the putative protection of MK-801 and 6,7-dinitroquinoxaline-2,3-dione (DNQX), were investigated by morpho...

journal_title：Neuroscience letters

authors： Villani L,Carraro S,Guarnieri T

更新日期：1995-06-09 00:00:00

abstract：:Intracellular recordings were made from rat striatal neurones in vitro. In the presence of intracellular caesium and extracellular tetraethylammonium chloride (TEA) (5 mM) and barium (3 mM), long-lasting plateau potentials developed followed by a prominent voltage independent hyperpolarization which lasted several sec...

journal_title：Neuroscience letters

authors： Cherubini E,Lanfumey L

更新日期：1987-08-05 00:00:00

abstract：:In this paper, functional connectivity of steady-state visual evoked potential (SSVEP) was investigated. Directed transfer function (DTF) was applied to cortical signals recorded from electroencephalography (EEG) in order to obtain connectivity patterns. Flow gain was proposed to assess the role of the specific brain ...

journal_title：Neuroscience letters

authors： Yan Z,Gao X

更新日期：2011-07-25 00:00:00

abstract：:We combined fluorescent tracing with immunohistochemistry to examine nitric oxide synthase (NOS) containing neurons in the rat ventral lateral geniculate nucleus (vLGN). NOS immunopositive neurons in vLGN had a similar appearance to previously described NADPH-d positive neurons. The majority (96%) of the NOS immunopos...

journal_title：Neuroscience letters

authors： Meng XW,Ohara PT,Ralston HJ 3rd

更新日期：1998-11-06 00:00:00

abstract：:The effects of glutamate uptake inhibitors on the L-glutamate-induced increase in intracellular calcium concentrations were assessed in rat primary cortical cultures. The glutamate (10 microM)-induced rise in intracellular calcium concentrations was strongly and dose dependently increased and prolonged by simultaneous...

journal_title：Neuroscience letters

authors： Freund WD,Grieshop B,Neumann U,Reddig S

更新日期：1995-03-16 00:00:00

abstract：:The human nervous system displays remarkable functional plasticity following long-term sensory deprivation. For example, the auditory cortex of congenitally deaf humans may start to process tactile information. To further explore this type of cross-modal plasticity, we examined the tactile accuracy of congenitally dea...

journal_title：Neuroscience letters

authors： Levänen S,Hamdorf D

更新日期：2001-03-23 00:00:00

abstract：:There are many evidences suggest that ascorbate in the extracellular space can affect glutamate concentration in the rat's brain. In this report, we studied how ascorbate in microdialysis perfusion medium affected glutamate level at the striatum in freely-moving rats. Three perfusion mediums were used: 0, 250, and 400...

journal_title：Neuroscience letters

authors： Lai YJ,Shen EY,Pan WH

更新日期：2000-02-04 00:00:00

abstract：:Respiration can be automatic or controlled behaviorally. Behavioral control in the cat occurs, at least in part, through control of the brainstem respiratory neurons that constitute the automatic system. Thus, when inspiration is inhibited behaviorally, inspiratory neurons in the medulla are inactivated. Reported here...

journal_title：Neuroscience letters

authors： Orem J

更新日期：1987-12-29 00:00:00

abstract：:Analyses of neural mechanisms of duration processing are essential for the understanding of psychological phenomena which evolve in time. Different mechanisms are presumably responsible for the processing of shorter (below 500 ms) and longer (above 500 ms) events but have not yet been a subject of an investigation wit...

journal_title：Neuroscience letters

authors： Gutyrchik E,Churan J,Meindl T,Bokde AL,von Bernewitz H,Born C,Reiser M,Pöppel E,Wittmann M

更新日期：2010-01-29 00:00:00

abstract：:Previous studies have shown that striatum and nucleus accumbens (NAc) are two different structures in mediating addictive drug-induced ascorbic acid (AA) release. In order to further characterize the different effects of drugs-induced AA release in the striatum and NAc, in the present study, we investigated the effect...

journal_title：Neuroscience letters

authors： Gu PF,Wu CF,Yang JY,Shang Y,Hou Y,Bi XL,Dai F

更新日期：2006-05-15 00:00:00

abstract：:In vivo electrochemistry was used to determine the effects of locally applied raclopride (a D2 receptor antagonist) and SCH-23390 (a D1 receptor antagonist) on the clearance of locally applied dopamine in the striatum, nucleus accumbens, and medial prefrontal cortex of rats. Chronoamperometric recordings were continuo...

journal_title：Neuroscience letters

authors： Cass WA,Gerhardt GA

更新日期：1994-08-01 00:00:00

abstract：:The enzyme Fatty Acid Amide Hydrolase (FAAH) is a key regulator of the endogenous levels of a family of biologically active lipid mediators, the fatty acid amides. These include anandamide, oleoyl ethanolamide and palmitoyl ethanolamide, and their effects are mediated by a variety of downstream targets including canna...

journal_title：Neuroscience letters

authors： Webb M,Luo L,Ma JY,Tham CS

更新日期：2008-07-04 00:00:00

abstract：:Pineal serotonin (5-HT), 5-hydroxyindole-acetic acid (5-HIAA), norepinephrine (NE), epinephrine (E) and adrenal corticosterone, NE and E contents were measured spectrofluorometrically 5, 15, 30 and 60 min after insulin treatment to induce hypoglycemic stress. In the pineal gland, hypoglycemic stress caused dramatic de...

journal_title：Neuroscience letters

authors： Mahata SK

更新日期：1991-01-02 00:00:00

abstract：:Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Identifying PD cognitive impairment (PDCI) in the early stage will help slow or prevent PD dementia. Susceptibility loci for PDCI are inconsistent in different studies. The aim of this study is to determine susceptibility loci for PDCI in t...

journal_title：Neuroscience letters

authors： Liu HJ,Li XY,Chen H,Yu HL,Tao QQ,Wu ZY

更新日期：2020-06-21 00:00:00

abstract：:While past research suggests that ghrelin stimulates appetite through an action on hypothalamic signaling, recent evidence indicates that the peptide acts via mesotelencephalic dopamine neurons to alter appetitive motivation. In the present study, rats were trained to operantly respond for food on a progressive ratio ...

journal_title：Neuroscience letters

authors： Weinberg ZY,Nicholson ML,Currie PJ

更新日期：2011-07-20 00:00:00

abstract：:Post-transcriptional control of gene expression by microRNAs provides an important regulatory system within neurons, allowing co-ordinate and fine-tuned expression of plasticity-related proteins. Indeed, specific microRNAs have been shown to be regulated by synaptic activity in the dentate gyrus, and contribute to the...

journal_title：Neuroscience letters

authors： Ryan B,Williams JM

更新日期：2019-08-10 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) immunoreactive afferent nerves were seen intrarenally by prenatal day 16. They grow rapidly and CGRP positive nerves are observed at birth associated with the arterial and venous vascular tree, forming a rich plexus in the pelvic region and in the connective tissue located near t...

journal_title：Neuroscience letters

authors： Barajas L,Liu L,Nishiyama C

更新日期：1991-12-09 00:00:00

abstract：:The noradrenergic system modulates attention and arousal. Dysregulation of the noradrenergic system may be involved in the pathophysiology of attention-deficit/hyperactivity disorder (ADHD). This study intended to examine the differences in methylphenidate (MPH) treatment response and pre- and post-treatment cerebral ...

journal_title：Neuroscience letters

authors： Park MH,Kim JW,Yang YH,Hong SB,Park S,Kang H,Kim BN,Shin MS,Yoo HJ,Cho SC

更新日期：2012-04-18 00:00:00

abstract：:L-arginine is a very versatile amino acid that is involved in many important physiological processes such as protein, nitric oxide (NO), agmatine, putrescine, urea, L-ornithine or creatine synthesis and is essential for posttranslational arginylation of protein. The present study was designed to evaluate in vivo the e...

journal_title：Neuroscience letters

authors： Castellano MA,Rojas-Díaz D,Martín F,Quintero M,Alonso J,Navarro E,González-Mora JL

更新日期：2001-11-16 00:00:00

abstract：:Auditory learning induces frequency-specific plasticity in the auditory cortex. Both the auditory cortex and thalamus are involved in the cortical plasticity; however, the precise role of the intracortical circuity remains unclear until the contributions of the thalamocortical inputs are controlled. Here, we induced c...

journal_title：Neuroscience letters

authors： Kong L,Wang S,Liu X,Li L,Zeeman M,Yan J

更新日期：2018-03-06 00:00:00

abstract：:The effect of aconitine, a plant alkaloid known to bind at site 2 of the sodium channel, was investigated on neuronal excitability in hippocampal slices of adult and juvenile rats. Aconitine (0.01-1 microM) diminished the extracellularly recorded population spike in a concentration-dependent manner. At each concentrat...

journal_title：Neuroscience letters

authors： Ameri A

更新日期：1996-09-20 00:00:00

abstract：:The study of neural arousal mechanisms has been greatly aided by the discovery of the orexin peptides (orexin A and orexin B), the subsequent identification of the neurons that synthesize these peptides, their projections in the brain, and the distribution of orexin receptors in the central nervous system. Orexin neur...

journal_title：Neuroscience letters

authors： Brown TM,Coogan AN,Cutler DJ,Hughes AT,Piggins HD

更新日期：2008-12-31 00:00:00

abstract：:The terpene lactones of Ginkgo biloba extract, namely ginkgolides (A, B, and C) and bilobalide, possess antioxidant, anti-inflammatory, and neuroprotective effects. They are widely prescribed for the treatment of cerebral dysfunctions and neurological impairments. In addition, they demonstrate antagonistic action at t...

journal_title：Neuroscience letters

authors： Nishimon S,Yamaguchi M,Muraki H,Sakai N,Nishino S

更新日期：2020-03-23 00:00:00

abstract：:We have assessed whether apolipoprotein E (ApoE) genotype influences the age of onset of dementia in a series of families with frontal temporal dementia with defined mutations in the tau gene. In contrast to the situation in Alzheimer's disease (AD), we could find no evidence that the age of onset of disease was influ...

journal_title：Neuroscience letters

authors： Houlden H,Rizzu P,Stevens M,de Knijff P,van Duijn CM,van Swieten JC,Heutink P,Perez-Tur J,Thomas V,Baker M,Morris H,Rossor M,Jannsen JC,Petersen RC,Dodd P,Dark F,Boeve B,Dickson D,Davies P,Pickering-Brown S,Mann D

更新日期：1999-02-05 00:00:00