6,7-Dinitroquinoxaline-2,3-dione but not MK-801 exerts a protective effect against kainic acid neurotoxicity in the goldfish retina.

abstract：:The distribution of neurons expressing beta-endorphin immunoreactivity was explored in the brain of adult jerboa during two distinct periods characterizing its reproductive cycle. A large presence of cell bodies displaying beta-endorphin immunoreactivity occured within different parts of the mediobasal hypothalamus al...

journal_title：Neuroscience letters

authors： El Ouezzani S,Tramu G,Magoul R

更新日期：2005-03-11 00:00:00

abstract：:In the last decade, several genes have been linked to Parkinson's disease (PD), including GIGYF2, ATP13A2 and GBA. To explore whether mutations in these genes contribute to development of PD in the Brazilian population, we screened 110 patients with early-onset PD. No clearly pathogenic mutations were identified in AT...

journal_title：Neuroscience letters

authors： Dos Santos AV,Pestana CP,Diniz KR,Campos M,Abdalla-Carvalho CB,de Rosso AL,Pereira JS,Nicaretta DH,de Carvalho WL,Dos Santos JM,Santos-Rebouças CB,Pimentel MM

更新日期：2010-11-19 00:00:00

abstract：:Advanced aging is accompanied by a decline in visuospatial attention. Previous neuroimaging and electrophysiological studies have demonstrated dysfunction in specific brain areas related to visuospatial attention. However, it is still unclear how the functional connectivity between brain regions causes the decline of ...

journal_title：Neuroscience letters

authors： Li Y,Li C,Wu Q,Xu Z,Kurata T,Ohno S,Kanazawa S,Abe K,Wu J

更新日期：2015-06-15 00:00:00

abstract：:Although the guinea pig is used widely in experimental medical research, including in studies on micturition control, the spinal origin of preganglionic parasympathetic bladder and somatic external urethral sphincter motoneurons is not known. In the male guinea pig using wheat germ agglutinin-conjugated horseradish pe...

journal_title：Neuroscience letters

authors： Kuipers R,Izhar Z,Gerrits PO,Miner W,Holstege G

更新日期：2004-05-13 00:00:00

abstract：:The Lama2dy mouse, a model of congenital muscular dystrophy (CMD) by merosin deficiency (MCMD), shows muscle degeneration and dysmyelination of peripheral nerves. Although it has been reported that MCMD reduces acetylcholinesterase (AChE) activity of mouse sciatic nerve, no information is available regarding its actio...

journal_title：Neuroscience letters

authors： Moral-Naranjo MT,Cabezas-Herrera J,Vidal CJ,Campoy FJ

更新日期：2002-10-18 00:00:00

abstract：:Activated microglia surround degenerating substantia nigra neurons in Parkinson's disease (PD). Such microglia produce high levels of interleukin-1 beta (IL-1 beta) and interleukin-1 alpha (IL-1 alpha). T and C alleles exist for the IL-1 beta-511 regulatory region as well as for the IL-1 alpha-889 regulatory region. T...

journal_title：Neuroscience letters

authors： McGeer PL,Yasojima K,McGeer EG

更新日期：2002-06-21 00:00:00

abstract：:Intellectual disability (ID) is one of the most prevalent chronic developmental brain disorders or phenotype of syndromic ID, affecting nearly 1-2% of the general population worldwide. Over recent decades, tremendous effort and high-throughput platforms have been devised to explore the complex heterogeneity, numerous ...

journal_title：Neuroscience letters

authors： Chen C,Chen D,Xue H,Liu X,Zhang T,Tang S,Li W,Xu X

更新日期：2018-10-15 00:00:00

abstract：:The ability of three nitric oxide (NO) donor compounds to modify ligand binding to kainate receptors was studied in tissue from human adult autopsy brains. Binding of [3H]kainic acid (5 nM) was measured in frontal cortex membranes made from Brodmann area 8 (BA 8) and autoradiographically using sections of frontal cort...

journal_title：Neuroscience letters

authors： Lees RD,Slater P,D'Souza SW

更新日期：1997-09-19 00:00:00

abstract：:Nociceptin/orphanin FQ (N/OFQ) is an endogenous peptide agonist for the opioid receptor homolog, N/OFQ receptor, and serves for the central control of autonomic functions. Morphological details including the cell types that may account for such N/OFQ functions, however, remain unclear. By using X-gal histochemistry fo...

journal_title：Neuroscience letters

authors： Houtani T,Ikeda M,Kase M,Sato K,Sakuma S,Kakimoto S,Ueyama T,Munemoto Y,Takeshima H,Sugimoto T

更新日期：2003-01-02 00:00:00

abstract：:Fluorescent tracers (Nuclear Yellow, True Blue, Fast Blue) were injected, in various combinations, into the globus pallidus and substantia nigra in three marmosets. Examination of perikarya in the ipsilateral neostriatum, well removed from pallidal injection sites, revealed that the predominant pattern was of single-l...

journal_title：Neuroscience letters

authors： Féger J,Crossman AR

更新日期：1984-08-24 00:00:00

abstract：:Triazolam can shift the phase of circadian rhythms in hamsters recorded in constant light or dark. This effect is apparently mediated by physical activity stimulated by the drug. We examined whether triazolam can shift the phase of circadian rhythms in a diurnal primate, the squirrel monkey, that is sedated by triazol...

journal_title：Neuroscience letters

authors： Mistlberger RE,Houpt TA,Moore-Ede MC

更新日期：1991-03-11 00:00:00

abstract：BACKGROUND:A single session of aerobic exercise is linked to faster motor responses; however, the effect on rate of short-term learning is less clear. The objective was to evaluate the influence of a single bout of aerobic exercise on the rate of short-term acquisition of a shape-letter association task requiring a mot...

journal_title：Neuroscience letters

authors： Sage MD,Beyer KB,Laylor M,Liang C,Roy EA,McIlroy WE

更新日期：2016-08-26 00:00:00

abstract：:We and others have previously reported that neurons expressing neuronal nitric oxide synthase (nNOS) do not co-express GTP cyclohydrolase I, the enzyme that synthesize its cofactor tetrahydrobiopterin (BH4). BH4 is released from catecholaminergic cells and nNOS-expressing cells are located close to BH4-producing catec...

journal_title：Neuroscience letters

authors： Choi HJ,Kim SW,Im JH,Lee SG,Kim M,Hwang O

更新日期：2003-12-04 00:00:00

abstract：:It is debated whether non-affected relatives of patients with affective disorders share a specific brain structure endophenotype. Aim of this work is to explore the medial temporal morphology in affected and non-affected members of a family with mood disorders. Hippocampi and amygdalae were manually traced from the 3D...

journal_title：Neuroscience letters

authors： Boccardi M,Almici M,Bresciani L,Caroli A,Bonetti M,Monchieri S,Gennarelli M,Frisoni GB

更新日期：2010-01-04 00:00:00

abstract：:Huntington disease is an uncommon autosomal dominant neurodegenerative disorder caused by expanded polyglutamine repeats in the huntingtin protein. The proximate mechanisms responsible for neurodegeneration are unknown. Copper ions may play a role in Huntington disease by promoting oligomerization of expanded polyglut...

journal_title：Neuroscience letters

authors： Tallaksen-Greene SJ,Janiszewska A,Benton K,Hou G,Dick R,Brewer GJ,Albin RL

更新日期：2009-03-06 00:00:00

abstract：:Developing novel neuroprotective strategies for the treatment of Parkinson's disease (PD) is of great importance. We have previously shown that vascular endothelial growth factor-B (VEGF-B) is up-regulated in an in vitro model of PD using the neurotoxin rotenone. Addition of exogenous VEGF-B(167) was neuroprotective i...

journal_title：Neuroscience letters

authors： Falk T,Yue X,Zhang S,McCourt AD,Yee BJ,Gonzalez RT,Sherman SJ

更新日期：2011-05-27 00:00:00

abstract：:A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes, including the activation of inflammatory cytokines. We performed a case-control association study between sporadic AD patients and the exon 5 position +3953 polymorphism in the potent pro-inflammatory cyt...

journal_title：Neuroscience letters

authors： Rosenmann H,Meiner Z,Dresner-Pollak R,Kahana E,Aladjem Z,Grenader T,Wertman E,Abramsky O

更新日期：2004-06-10 00:00:00

abstract：:We developed a novel procedure for efficient mutagenesis of zebrafish using a DNA cross-linking agent 4,5',8-trimethylpsoralen (TMP), which is known to frequently induce small deletions in Escherichia coli and Caenorhabditis elegans. A specific-locus test and pilot screenings indicated that the TMP mutagenesis procedu...

journal_title：Neuroscience letters

authors： Ando H,Mishina M

更新日期：1998-03-13 00:00:00

abstract：:Ts65Dn (TS), control littermates (CO) and Swiss (SW) male mice were tested in the elevated plus-maze and in the Morris water maze (MWM) for memory evaluation. In the plus-maze, each mouse was placed at the end of an open arm and initial freezing and the time to enter into an enclosed arm (transfer latency) were measur...

journal_title：Neuroscience letters

authors： Escorihuela RM,Vallina IF,Martínez-Cué C,Baamonde C,Dierssen M,Tobeña A,Flórez J,Fernández-Teruel A

更新日期：1998-05-15 00:00:00

abstract：:We investigated the possibility of obtaining an anteroposterior body response to galvanic vestibular stimulation (GVS) by applying an equivalent stimulus to both sides of the vestibular apparatus. An original 'double fronto-mastoidal' stimulation was used on eight subjects standing with their head facing forwards. Bot...

journal_title：Neuroscience letters

authors： Séverac Cauquil A,Gervet MF,Ouaknine M

更新日期：1998-03-27 00:00:00

abstract：:Acute alcohol challenge suppresses the mismatch negativity (MMN) component of the auditory event-related potential (ERP), however, the transmitter systems underlying MMN generation/mediating this effect have remained vague. To test adenosinergic contribution, 12 healthy social drinkers participated in four sessions, i...

journal_title：Neuroscience letters

authors： Hirvonen J,Jääskeläinen IP,Näätänen R,Sillanaukee P

更新日期：2000-01-07 00:00:00

abstract：:Leucine-enkephalin-like immunoreactive (ENK-LI) afferent fibers to the feline homologue of the Onuf's nucleus (pudendal motoneurons) originate mainly from lamina X of the sacral cord. They make synaptic contacts chiefly upon dendrites of pudendal motoneurons; the synaptic terminals most often contain pleomorphic synap...

journal_title：Neuroscience letters

authors： Konishi A,Itoh K,Sugimoto T,Yasui Y,Kaneko T,Takada M,Mizuno N

更新日期：1985-10-24 00:00:00

abstract：:Cholinergic projections originating in the basal forebrain (BF) play important roles in the heterosynaptic facilitation of synaptic strength in various sensory cortices, including the primary visual cortex (V1). Here, using urethane-anesthetized rats, we find that pairing burst stimulation of the BF with single pulse ...

journal_title：Neuroscience letters

authors： Gagolewicz PJ,Dringenberg HC

更新日期：2009-10-02 00:00:00

abstract：:The etiology of schizophrenia is unknown, but the pathogenetic process involves organic changes in brain tissue, which may alter the composition of cerebrospinal fluid (CSF). For the present study, CSF was obtained by lumbar puncture from 22 schizophrenic patients and 38 control patients. We have used scanning electro...

journal_title：Neuroscience letters

authors： Wetterberg L,Nybom R,Bratlid T,Fladby T,Olsson B,Wigzell H

更新日期：2002-08-23 00:00:00

abstract：:In freely moving rats, effects of unilateral haloperidol injection into the substantia nigra were monitored with in vivo voltammetry in the bilateral striata. The electrochemical responses at 120 mV versus Ag-AgCl, reflecting mainly a level of 3,4-dihydroxyphenylacetic acid (DOPAC), increased both in the striata withi...

journal_title：Neuroscience letters

authors： Kato T,Ishii K,Ikeda M

更新日期：1984-09-07 00:00:00

abstract：:We aimed to evaluate the effects of l-dopa use on apparent diffusion coefficient (ADC) values of different brain regions in Parkinson's disease (PD) patients. Thirty-five subjects underwent magnetic resonance imaging (MRI), including 21 PD patients (13 men, 8 women; mean age, 63 years+/-8), and 14 sex and age-matched ...

journal_title：Neuroscience letters

authors： Degirmenci B,Yaman M,Haktanir A,Albayrak R,Acar M,Caliskan G

更新日期：2007-04-18 00:00:00

abstract：:Advanced glycation end products (AGEs) in the brain were immunohistochemically examined in Alzheimer's disease (AD) and aging using anti-AGE antibody recognizing mainly carboxymethyllysine. AGE positive staining diffusely located in the neuronal perikarya of hippocampus and parahippocampus in AD and aged brains withou...

journal_title：Neuroscience letters

authors： Takedo A,Yasuda T,Miyata T,Mizuno K,Li M,Yoneyama S,Horie K,Maeda K,Sobue G

更新日期：1996-12-27 00:00:00

abstract：:The co-localization of neuropeptide tyrosine (NPY) and somatostatin (SOM) in rat hippocampal cells was studied in double labelling experiments using a combination of antibodies against the two peptides on the same tissue section. The individual hippocampal subfields show large variations in the relative number of NPY-...

journal_title：Neuroscience letters

authors： Köhler C,Eriksson LG,Davies S,Chan-Palay V

更新日期：1987-07-09 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine involved in the development and maintenance of inflammatory and neuropathic pain conditions. The mechanisms by which TNF-alpha elicits pain behavior are still incompletely understood. Numerous studies suggest that TNF-alpha sensitizes primary affere...

journal_title：Neuroscience letters

authors： Czeschik JC,Hagenacker T,Schäfers M,Büsselberg D

更新日期：2008-04-04 00:00:00

abstract：:The melanocortin receptor type 2 (MC2R or adrenocorticotropic hormone, ACTH receptor) gene (MC2R) encodes a protein involved in regulation of adrenal cortisol secretion, important in the physiological response to stressors. A variant of MC2R, -179A>G, results in reduction of promoter activity and less adrenal action. ...

journal_title：Neuroscience letters

authors： Proudnikov D,Hamon S,Ott J,Kreek MJ

更新日期：2008-04-25 00:00:00