The mesolimbic dopamine system: evidence for a high amine turnover and for a heterogeneity of the dopamine neuron population.

Abstract:

:By means of a new photographic method to quantitate catecholamine fluorescence in tissue sections it has been possible to demonstrate a high dopamine (DA) turnover within the DA cell bodies of the midbrain. The medially located small-sized DA cell bodies of the A10 DA cell group has a very high DA turnover which was significantly different from that found in the laterally located medium-sized DA cell bodies of the A10 cell group. Thus, the mesolimbic DA pathways may be divided into two systems, the medial system having a very high DA turnover in their cell bodies which may reflect a high functional activity in this system.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Agnati LF,Fuxe K,Andersson K,Benfenati F,Cortelli P,D'Alessandro R

doi

10.1016/0304-3940(80)90211-6

subject

Has Abstract

pub_date

1980-05-15 00:00:00

pages

45-51

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(80)90211-6

journal_volume

18

pub_type

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