当前位置： SCI文献检索 > NEUROSCIENCE LETTERS期刊下所有文献 > Investigation of the primary visual cortex using short-interval paired-pulse transcranial magnetic stimulation (TMS).

Investigation of the primary visual cortex using short-interval paired-pulse transcranial magnetic stimulation (TMS).

Abstract：

:Previous studies using short-interval paired-pulse TMS have provided valuable insights into physiology of human motor cortex. Depending on the interstimulus interval (ISI) between the two pulses intra-cortical facilitation (ICF) or intra-cortical inhibition (ICI) can be observed. Similar patterns of inhibition and facilitation have also been demonstrated in prefrontal and parietal cortices. In order to prove whether principles that govern cortical excitability in the motor system also extend to the visual system and to further characterize possible neural correlates of phosphene generation, we applied short-interval paired-pulse TMS to the occipital cortex. In addition, we examined the effect of different coil orientations on perception of phosphenes induced by paired-pulse TMS. In all of 10 healthy subjects, a general facilitation of phosphene perception could be observed for interstimulus intervals of 2-12 ms (conditioning stimulus (CS) 90% and test stimulus (TS) 100% of subject's phosphene threshold) compared to TS alone. With CS intensity decreasing to 80% or less, the effect diminished. No significant changes occurred when TS intensity was increased to 110%. Phosphene perception was enhanced with an induced current direction from lateral to medial at an ISI of 12 ms. Inhibition was not observed in any condition. Our results indicate that the mechanisms underlying phosphene induction in the visual cortex are different from those underlying intracortical inhibition and facilitation in the motor cortex.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Sparing R,Dambeck N,Stock K,Meister IG,Huetter D,Boroojerdi B

doi

10.1016/j.neulet.2005.03.036

keywords:

subject

Has Abstract

pub_date

2005-07-15 00:00:00

pages

312-6

issue

3

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(05)00331-9

journal_volume

382

pub_type

杂志文章

相关文献

NEUROSCIENCE LETTERS文献大全
  • Gene editing based hearing impairment research and therapeutics.

    abstract：:Hearing impairment affects 1 in 500 newborns worldwide and nearly one out of three people over the age of 65 (WHO, 2019). Hereditary hearing loss is the most common type of congenital deafness; genetic factors also affect deafness susceptibility. Gene therapies may preserve or restore natural sound perception, and hav...

    journal_title：Neuroscience letters

    pub_type： 杂志文章,评审

    doi：10.1016/j.neulet.2019.134326

    authors： Kang W,Sun Z,Zhao X,Wang X,Tao Y,Wu H

    更新日期：2019-09-14 00:00:00

  • Adolescent morphine induces emotional signs of withdrawal paired with neurotoxicity selectively in male rats: Female resilience.

    abstract：:This study evaluated the immediate and persistent behavioral and molecular consequences (i.e., emotional signs emerging during withdrawal and signs of neurotoxicity) following adolescent morphine exposure with a sex perspective. Basally, and prior to drug treatment, adolescent female rats showed smaller body weight an...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2019.134625

    authors： Jiménez-Romero F,Bis-Humbert C,García-Fuster MJ

    更新日期：2020-01-10 00:00:00

  • NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase.

    abstract：:Previous studies have showed that SIN-1, a nitric oxide (NO) donor, injected into the dorsolateral column of the periaqueductal gray (dlPAG) induces flight reactions. This drug, however, can also produce peroxynitrite, which may interfere in this effect. In addition, it is also unknown if this effect is mediated by lo...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2009.05.009

    authors： Braga AA,Aguiar DC,Guimarães FS

    更新日期：2009-08-07 00:00:00

  • Evoked EEG alpha oscillations in the cat brain--a correlate of primary sensory processing?

    abstract：:Event-related alpha (10 Hz) oscillations in the EEG were measured in cats by means of intracranial electrodes. Simultaneous recordings were made from auditory and visual cortex while auditory and visual stimuli were applied (in separate sessions). Frequency domain analysis of the EEG responses showed marked alpha comp...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(97)00926-9

    authors： Schürmann M,Başar-Eroglu C,Başar E

    更新日期：1998-01-02 00:00:00

  • Sympathetic nervous system mediates cold stress-induced suppression of natural killer cytotoxicity in rats.

    abstract：:The aim of the present study is to investigate the mechanisms of suppression of splenic natural killer (NK) cytotoxicity caused by cold stress, using 6-hydroxydopamine (6-OHDA) as chemical sympathectomy. The NK activity was measured by (51)chromium release assay. Central sympathectomy with intracerebroventricular inje...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2003.11.007

    authors： Jiang XH,Guo SY,Xu S,Yin QZ,Ohshita Y,Naitoh M,Horibe Y,Hisamitsu T

    更新日期：2004-03-18 00:00:00

  • Antioxidants prevent ethanol-induced contractions of canine cerebral vascular smooth muscle: relation to alcohol-induced brain injury.

    abstract：:The present study was designed to test the hypothesis that alpha-tocopherol (Vit. E) and pyrrolidine dithiocarbamate (PDTC) might exert direct effects on alcohol-induced contractions of canine basilar cerebral arteries. After precontraction of arterial ring segments with ethanol, PDTC (10(-8)-10(-6) M) and Vit. E (10(...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(01)01588-9

    authors： Li W,Zheng T,Altura BT,Altura BM

    更新日期：2001-03-30 00:00:00

  • Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related gamma-secretase.

    abstract：:Anterior pharynx-defective 1 (Aph-1) is a multi-spanning membrane protein and an integral component of the high molecular weight gamma-secretase complex that also contains presenilin, nicastrin, and Pen-2. In order to clarify the existence of an endogenous fragment of Aph-1 and dissect the localization and processing ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2010.07.061

    authors： Sanjo N,Katayama T,Hasegawa H,Jin H,Duthie M,Mount HT,Mizusawa H,St George-Hyslop P,Fraser PE

    更新日期：2010-10-08 00:00:00

  • Staurosporine and H7 attenuate ethanol-induced elevation in [Ca2+]i in cultured canine cerebral vascular smooth muscle cells.

    abstract：:Chronic exposure of cultured canine cerebral vascular smooth muscle cells to ethanol (10-400 mM) for 1-5 days resulted in significant concentration-dependent elevation in resting intracellular free calcium ([Ca2+]i) levels. Preincubation of these cultured vascular cells with inhibitors of protein kinase C (PKC), staur...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(98)00016-0

    authors： Zheng T,Li W,Zhang A,Altura BT,Altura BM

    更新日期：1998-01-30 00:00:00

  • Lack of cyclic AMP-specific phosphodiesterase 4 activation during naloxone-precipitated morphine withdrawal in rats.

    abstract：:Intracellular cyclic AMP regulation systems play an important role in the mechanisms of morphine dependence and withdrawal. In the present study, to clarify the involvement of phosphodiesterase (PDE) 4, degradation enzyme of cyclic AMP in morphine dependence and withdrawal we investigated the activities of PDE4 after ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2006.05.014

    authors： Kimura M,Tokumura M,Itoh T,Inoue O,Abe K

    更新日期：2006-08-14 00:00:00

  • VEGF-mediated NF-κB activation protects PC12 cells from damage induced by hypoxia.

    abstract：:Neuronal apoptosis is a contributing cause of disability and death in cerebral ischemia. Nuclear factor-κB (NF-κB) may become a potential therapeutic target for hypoxic/ischemic neuron damage because NF-κB is inactivated after hypoxia exposure. Vascular endothelial growth factor (VEGF) has been found to improve neurol...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2015.10.051

    authors： Mo SJ,Hong J,Chen X,Han F,Ni Y,Zheng Y,Liu JQ,Xu L,Li Q,Yang XH,Sun RH,Yin XY

    更新日期：2016-01-01 00:00:00

  • Intracellular amyloid induces impairments on electrophysiological properties of cultured human neurons.

    abstract：:The role of intracellular amyloid beta (iAbeta) in Alzheimer's disease (AD) initiation and progression attracts more and more attention in recent years. To address whether iAbeta induces early alterations of electrophysiological properties in cultured human primary neurons, we delivered iAbeta with adeno-virus and mea...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2009.07.031

    authors： Hou JF,Cui J,Yu LC,Zhang Y

    更新日期：2009-10-25 00:00:00

  • Influence of task difficulty on the features of event-related potential during visual oddball task.

    abstract：:We present a comprehensive analysis of the change in event-related potential (ERP) due to task difficulty during a visual oddball task. Specifically, we investigated the inter-subject difference in difficulty-related change of ERP patterns using single-trial ERP analysis focusing on P300 and P2 components. ERPs were r...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2008.09.004

    authors： Kim KH,Kim JH,Yoon J,Jung KY

    更新日期：2008-11-14 00:00:00

  • Antiepileptic effect of electroacupuncture vs. vagus nerve stimulation in the rat thalamus.

    abstract：:Our previous study has shown that both electroacupuncture (EA) and vagus nerve stimulation (VNS) can inhibit cortical epileptiform activities induced by pentylenetetrazole (PTZ). The current study compared the effects of EA and VNS on thalamic neuronal responses to PTZ-induced epileptiform activities. Under general an...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2008.06.032

    authors： Zhang JL,Zhang SP,Zhang HQ

    更新日期：2008-08-22 00:00:00

  • Postischemic hypothermia induced by eugenol protects hippocampal neurons from global ischemia in gerbils.

    abstract：:We studied whether eugenol provides neuroprotection against delayed neuronal death in the hippocampal CA1 region following a 5 min occlusion of the common carotid arteries bilaterally under either free-regulating temperature (TF) or maintained temperature (TM, 37 degrees C) conditions in gerbils. Right after occlusion...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(98)00664-8

    authors： Won MH,Lee JC,Kim YH,Song DK,Suh HW,Oh YS,Kim JH,Shin TK,Lee YJ,Wie MB

    更新日期：1998-09-25 00:00:00

  • 5-Hydroxytryptamine increases spontaneous activity of subthalamic neurons in the rat.

    abstract：:The effect of 5-hydroxytryptamine on the spontaneous activity of neurons of the subthalamic nucleus was examined by recording the extracellular unitary activity in an in vitro slice preparation. The most frequent response to 5-hydroxytryptamine (84% of 57 neurons tested) was an increase (twofold of basal at 10 microM)...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(95)11597-p

    authors： Flores G,Rosales MG,Hernández S,Sierra A,Aceves J

    更新日期：1995-06-02 00:00:00

  • Serotonin inhibits GABA synaptic transmission in presympathetic paraventricular nucleus neurons.

    abstract：:Activation of serotonin (5-hydroxytryptamine, 5-HT) receptors produces various autonomic and neuroendocrine responses in the hypothalamic paraventricular nucleus (PVN), including increased blood pressure and heart rate. However, the role(s) of 5-HT on the local GABA synaptic circuit have not been well understood in th...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2008.05.012

    authors： Lee KS,Han TH,Jo JY,Kang G,Lee SY,Ryu PD,Im JH,Jeon BH,Park JB

    更新日期：2008-07-11 00:00:00

  • The effect of somatostatin on striatal catecholamines.

    abstract：:Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(84)90034-x

    authors： Beal MF,Martin JB

    更新日期：1984-02-24 00:00:00

  • Long-interval facilitation and inhibition are differentially affected by conditioning stimulus intensity over different time courses.

    abstract：:Intracortical facilitatory and inhibitory processes in the primary motor cortex (M1) play an important role in both the preparation and execution of motor tasks. Here we aimed to (1) confirm the existence of, and further characterise, intracortical facilitation at long conditioning-test stimulus intervals at subthresh...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2014.03.060

    authors： Vallence AM,Schneider LA,Pitcher JB,Ridding MC

    更新日期：2014-06-06 00:00:00

  • An extract of the marine alga Alaria esculenta modulates α-synuclein folding and amyloid formation.

    abstract：:The conversion of α-synuclein from its natively unfolded and α-helical tetrameric forms to an amyloid conformation is central to the emergence of Parkinson's disease. Therefore, prevention of this conversion may offer an effective way of avoiding the onset of this disease or delaying its progress. At different concent...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2017.02.055

    authors： Giffin JC,Richards RC,Craft C,Jahan N,Leggiadro C,Chopin T,Szemerda M,MacKinnon SL,Ewart KV

    更新日期：2017-03-22 00:00:00

  • Molecular basis of 6-hydroxydopamine-induced caspase activations due to increases in oxidative stress in the mouse striatum.

    abstract：:To clarify the possible role of in the in vivo toxic effects of 6-hydroxydopamine (6-OHDA), especially caspase activations, we examined its effects on striatal lipid peroxidation (LPO) and caspase activations in 6-OHDA-lesioned mice. Both dopamine (DA) levels and DA turnover were significantly changed by the 6-OHDA i....

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2006.08.021

    authors： Tanaka K,Ogawa N,Asanuma M

    更新日期：2006-12-20 00:00:00

  • Correlation of tau gene polymorphism with age at onset of Parkinson's disease.

    abstract：:Parkinson's disease (PD) is a neurodegenerative disease and its prevalence increases with age. The microtubule-associated protein tau (MAPT) is thought to be implicated in the pathogenesis of PD. Association of the MAPT H1 haplotype with PD in Caucasians has been extensively studied, however, the results were inconsis...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2006.06.057

    authors： Kobayashi H,Ujike H,Hasegawa J,Yamamoto M,Kanzaki A,Sora I

    更新日期：2006-09-25 00:00:00

  • Neuronal intranuclear inclusions in spinocerebellar ataxia type 2: triple-labeling immunofluorescent study.

    abstract：:Spinocerebellar ataxia type 2 (SCA2) is associated with an expansion of CAG/polyglutamine-repeat of a gene of unknown function. We performed an immunohistochemical study to identify the immunolocalization of the disease protein ataxin-2 in normal and SCA2 patients. Although normal and expanded ataxin-2 were ubiquitous...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(99)00656-4

    authors： Koyano S,Uchihara T,Fujigasaki H,Nakamura A,Yagishita S,Iwabuchi K

    更新日期：1999-10-01 00:00:00

  • Effects of 5-(4-piperidyl) isoxazol-3-ol (4-PIOL), a GABA(A) receptor partial agonist, on recombinant human GABA(A) receptors.

    abstract：:gamma-Aminobutyric acidA (GABA(A)) gated chloride ion channels were expressed from human recombinant cDNA using the baculovirus/Sf-9 insect cell expression system. The electrophysiological effects in whole-cell currents of 5-(4-piperidyl) isoxazol-3-ol (4-PIOL), a GABA(A) receptor partial agonist, were investigated on...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(97)00473-4

    authors： Westh-Hansen SE,Noguchi K,Witt MR,Murai Y,Nielsen M,Akaike N

    更新日期：1997-07-11 00:00:00

  • Striatal cholinergic activity during morphine-induced catalepsy in the rat: development of tolerance.

    abstract：:Morphine hydrochloride (10 mg/kg,i.p.) induced marked catalepsy in rats, which was associated with significantly enhanced striatal acetylcholine levels and reduced cholinesterase activity. Rapid tolerance to morphine-induced catalepsy was noted after twice daily administrations, the tolerance being discernible after t...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(79)95355-2

    authors： Bose R,Kumar A,Bhattacharya SK

    更新日期：1979-09-01 00:00:00

  • Upregulation of Myo6 expression after traumatic stress in mouse hippocampus.

    abstract：:Traumatic stress has been believed to result in a variety of unusual alterations of the integrity and the functionality in the hippocampus. In this study, we searched for genes responsive to traumatic stress in the mouse hippocampus to elucidate the underlying mechanisms. Adult male mice were subjected to water-immers...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2007.12.062

    authors： Tamaki K,Kamakura M,Nakamichi N,Taniura H,Yoneda Y

    更新日期：2008-03-15 00:00:00

  • Dopamine receptors mediating the stimulation and the inhibition of adenylate cyclase in rat prostate gland.

    abstract：:The effect of dopamine on the 3',5'-cyclic adenosine monophosphate (cAMP) generating system of membrane particles of rat prostate gland was studied. Dopamine increased the concentration of cAMP in a dose-dependent manner. The selective D1 receptor inhibitor SCH 23390 caused a decrease in dopamine-elicited cAMP levels....

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(87)90608-2

    authors： Amenta D,Cavallotti C,Amenta F

    更新日期：1987-06-01 00:00:00

  • Lithium decreases turnover of arachidonate in several brain phospholipids.

    abstract：:In vivo rates of incorporation and turnover of palmitate and arachidonate in brain phospholipids were measured in awake rats treated chronically with lithium, following intravenous infusion of radiolabeled palmitate and arachidonate, respectively. Chronic lithium, at a brain level considered to be therapeutic in human...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(96)13264-x

    authors： Chang MC,Grange E,Rabin O,Bell JM,Allen DD,Rapoport SI

    更新日期：1996-12-20 00:00:00

  • The role of hepcidin in chronic mild stress-induced depression.

    abstract：:Depression is one of the most prevalent challenges of mental conditions. Yet its exact etiology has not been clear. Chronic stress increases the production of cytokines, which can lead to depression. Hepcidin, an iron modulator, is involved in the inflammation process as well as iron homeostasis. This study was design...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2015.01.008

    authors： Farajdokht F,Soleimani M,Mehrpouya S,Barati M,Nahavandi A

    更新日期：2015-02-19 00:00:00

  • Chronic phencyclidine increases methionine-enkephalin level in mouse striatum.

    abstract：:The chronic administration of phencyclidine-HCl (PCP-HCl), 10 mg/kg, for 6-7 days resulted in a significant increase in the striatal methionine-enkephalin level, although acute administration induced no change of methionine-enkephalin level in this area. The methionine-enkephalin levels in other areas investigated, i....

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(83)90506-2

    authors： Nabeshima T,Hiramatsu M,Amano M,Furukawa H,Kameyama T

    更新日期：1983-05-27 00:00:00

  • Molecular determinants of binding of a wasp toxin (PMTXs) and its analogs in the Na+ channels proteins.

    abstract：:The structural specificity of alpha-PMTX, a novel peptide toxin derived from wasp venom has been studied on the neuromuscular synapse in the walking leg of the lobster. alpha-PMTX is known to induce repetitive action potentials in the presynaptic axon due to sodium channel inactivation. We synthesized 29 analogs of al...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(00)01017-x

    authors： Konno K,Hisada M,Naoki H,Itagaki Y,Yasuhara T,Nakata Y,Miwa A,Kawai N

    更新日期：2000-05-05 00:00:00