Serotonin inhibits GABA synaptic transmission in presympathetic paraventricular nucleus neurons.

abstract：:We analyzed the participation of N-methyl-d-aspartate (NMDA) receptors in the neuronal damage caused by adult-onset hypothyroidism. Wistar rats were randomly assigned into four groups. The euthyroid group received tap water. The hypothyroid group received methimazole (60 mg/kg) in their drinking water to induce hypoth...

journal_title：Neuroscience letters

authors： Alva-Sánchez C,Becerril A,Anguiano B,Aceves C,Pacheco-Rosado J

更新日期：2009-04-10 00:00:00

abstract：:The intracellular stress-induced proteins provide protection against toxic insults. Here, a 60,000-Da heat shock 60 (hsp60)-like protein was detected, with five different antibodies, in conditioned media derived from rat cortical astrocytes and a human neuroblastoma cell line. Extracellular neuroblastoma hsp60-like im...

journal_title：Neuroscience letters

authors： Bassan M,Zamostiano R,Giladi E,Davidson A,Wollman Y,Pitman J,Hauser J,Brenneman DE,Gozes I

更新日期：1998-06-26 00:00:00

abstract：:The existence of long-term effects of dark-rearing on visuo-motor coordination is still controversial. In this study 2 dark-reared (DR) cats were trained, after 5-6 years of recovery, to perform a reaching movement towards a stationary or a moving target. The accuracy, and the reaction and movement times were evaluate...

journal_title：Neuroscience letters

authors： Fabre-Thorpe M,Levesque F,Gary-Bobo E

更新日期：1990-10-16 00:00:00

abstract：:The pedunculopontine tegmental nucleus (PPTg) contains cholinergic neurons whose principal ascending connections are with thalamic nuclei and structures associated with the striatum. It has been hypothesized that PPTg neurons are more closely associated with the substantia nigra (and therefore striatal motor systems) ...

journal_title：Neuroscience letters

authors： Jenkins TA,Latimer MP,Alderson HL,Winn P

更新日期：2002-03-29 00:00:00

abstract：:Alterations of 'peripheral-type' benzodiazepine receptors (PTBRs) in brain are a feature of hepatic encephalopathy (HE). Although ammonia toxicity has been implicated in the disorder, recent findings suggest an accumulation of manganese in the brains of cirrhotic patients dying in hepatic coma. In this study, we exami...

journal_title：Neuroscience letters

authors： Hazell AS,Desjardins P,Butterworth RF

更新日期：1999-08-13 00:00:00

abstract：:Schnurri-2 (Shn-2) knockout (KO) mice have been proposed as a preclinical neuroinflammatory schizophrenia model. We used behavioral studies and imaging markers that can be readily translated to human populations to explore brain effects of inflammation. Shn-2 KO mice and their littermate control mice were imaged with ...

journal_title：Neuroscience letters

authors： Choi JK,Zhu A,Jenkins BG,Hattori S,Kil KE,Takagi T,Ishii S,Miyakawa T,Brownell AL

更新日期：2015-11-16 00:00:00

abstract：:The spinal nucleus of the bulbocavernosus (SNB) in rodents is a neuromuscular system consisting of lumbar motoneurons and the perineal muscles they innervate, the bulbocavernosus and levator ani. This system is present prenatally in both males and females but degenerates postnatally in females because of the lack of p...

journal_title：Neuroscience letters

authors： Smith MR,Hamson DK,Poort JE,Jordan CL,Breedlove SM

更新日期：2012-04-04 00:00:00

abstract：:The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

journal_title：Neuroscience letters

authors： Healy J,Downes A,McBean GJ

更新日期：2000-08-25 00:00:00

abstract：:Treatment with agmatine, decarboxylated arginine, proved to be non-toxic and to exert neuroprotective effects in several models of neurotoxic and ischemic brain and spinal cord injuries. Here we sought to find out whether agmatine treatment would also prove beneficial in a rat spinal cord ischemia model (balloon occlu...

journal_title：Neuroscience letters

authors： Gilad GM,Gilad VH

更新日期：2000-12-22 00:00:00

abstract：:Representation of peripheral branches of the facial nerve within the facial nucleus of the cat was examined by utilizing retrograde axonal transport of horseradish peroxidase (HRP), which was injected into groups of muscles supplied by each of the main peripheral branches of the facial nerve. The cervical branch was r...

journal_title：Neuroscience letters

authors： Kume M,Uemura M,Matsuda K,Matsushima R,Mizuno N

更新日期：1978-04-01 00:00:00

abstract：:The effects of bilateral cut of the stria terminalis (ST) on the dosage of estradiol benzoate (EB) needed to induce the lordosis reflex in the ovariectomized female rat were examined. Seven different doses ranging 0.5-20 micrograms were given s.c. in oil, daily for 2 days in a counterbalanced order, at 3-week interval...

journal_title：Neuroscience letters

authors： Takeo T,Kudo M,Sakuma Y

更新日期：1995-01-23 00:00:00

abstract：:The effects of quinolinic acid (QUIN) on glutamate-induced excitotoxicity were examined in primary cultures of rat cerebellar granule neurons. Exposing these neurons to QUIN (< or =2.5 mM) in the presence of glucose and Mg2+ had no effect on their viability. Although pretreating neurons with QUIN (10 microM) for 6 h d...

journal_title：Neuroscience letters

authors： Sei Y,Fossom L,Goping G,Skolnick P,Basile AS

更新日期：1998-01-30 00:00:00

abstract：:It is well established that calcium-dependent neurotransmitter release and exocytosis can be regulated by altering the cholesterol content of the plasma membrane. We have compared the influence of cholesterol depletion of synaptosomal plasma membrane by 15 mM methyl-beta-cyclodextrin (MCD) treatment on calcium-depende...

journal_title：Neuroscience letters

authors： Waseem TV,Kolos VA,Lapatsina LP,Fedorovich SV

更新日期：2006-09-11 00:00:00

abstract：:A major action of adenosine is the induction of profound behavioral inactivity. 6-(4-Nitrobenzyl)-thioinosine (NBI) and 6-(2-hydroxy-5-nitrobenzyl)-thioguanosine (NBG) have been shown to inhibit adenosine uptake. To investigate the possible synergism between exogenous ligand and reuptake inhibition, mice were treated ...

journal_title：Neuroscience letters

authors： Crawley JN,Patel J,Marangos PJ

更新日期：1983-04-11 00:00:00

abstract：:The prioritized processing of threat is suggested to be motivated by anxiety, regulated by the parasympatheticus, and biased to the right hemisphere. However, according to an anterior dimensional model of negative affect this is unlikely to be true when threat is of social origin. Social threat is communicated by the ...

journal_title：Neuroscience letters

authors： van Honk J,Hermans EJ,d'Alfonso AA,Schutter DJ,van Doornen L,de Haan EH

更新日期：2002-02-15 00:00:00

abstract：:In this study we determined that cholinergic neurons from the lateral dorsal tegmental (LDT) and peribrachial pontine region (PPG) innervate the medial pontine reticular formation (medial PRF), a region involved in the generation of REM sleep. Wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) was injec...

journal_title：Neuroscience letters

authors： Shiromani PJ,Armstrong DM,Gillin JC

更新日期：1988-12-19 00:00:00

abstract：:The present investigation assessed the effect of chronic blockade of kainate/quisqualate binding sites with 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) on preproenkephalin (PPE) and preprotachykinin (PPT) mRNA abundance in the neostriatum of the rat brain. Daily injection of CNQX for seven consecutive days decreased P...

journal_title：Neuroscience letters

authors： Villegas M,Angulo JA

更新日期：1995-05-19 00:00:00

abstract：:Intracolonic (i.col.) administration of the PAR2-activating peptide (PAR2AP) SLIGRL-NH2 slowly develops visceral hypersensitivity to i.col. capsaicin in ddY mice. Thus, we further analyzed roles of PAR2 in colonic hypersensitivity, using the novel potent PAR2AP, 2-furoyl-LIGRL-NH2 and PAR2-knockout (KO) mice. In ddY m...

journal_title：Neuroscience letters

authors： Kawabata A,Kawao N,Kitano T,Matsunami M,Satoh R,Ishiki T,Masuko T,Kanke T,Saito N

更新日期：2006-07-10 00:00:00

abstract：:Although a linear correlation between oscillatory activities in the right and left motor cortices during movements has been shown in monkeys, there has been a debate whether scalp-recorded EEG coherence in human reflects a similar association. By applying partial coherence analysis, we demonstrated that interhemispher...

journal_title：Neuroscience letters

authors： Mima T,Matsuoka T,Hallett M

更新日期：2000-06-23 00:00:00

abstract：:By a double-labeling method combining the retrograde tracing of horseradish peroxidase and the immunocytochemical technique, serotonin-, substance P- or leucine-enkephalin-like immunoreactive neurons in the midbrain periaqueductal gray (PAG) and the nucleus raphe dorsalis (DR) of the rat were found to send projection ...

journal_title：Neuroscience letters

authors： Li YQ,Jia HG,Rao ZR,Shi JW

更新日期：1990-11-27 00:00:00

abstract：:Olivary hypertrophy, a combined retrograde and transneuronal reaction, is found in cells of the inferior olive after cerebellar ablation in the cat. Its chief features are central chromatolysis and hypertrophy of the peripherally located granular endoplasmatic reticulum with accumulation of electron-dense material in ...

journal_title：Neuroscience letters

authors： Boesten AJ,Voogd J

更新日期：1985-10-24 00:00:00

abstract：:Repeated or sustained exposure to opioids can not only induce analgesia but also long lasting enhancements in pain sensitivity, a phenomenon reported clinically and in animals. In rats, opioid-induced abnormal pain can be readily measured following continued delivery of morphine and the recruitment of descending facil...

journal_title：Neuroscience letters

authors： Suzuki R,Porreca F,Dickenson AH

更新日期：2006-10-23 00:00:00

abstract：:Kainic acid administration induces status epilepticus seizures in the rat which damage CA1 and CA3 hippocampal neurons. Rats made hypoglycemic prior to seizure had enhanced volumes of damage, when compared to normo- or hyperglycemic rats. The mild hypoglycemia was not in the range which, itself, typically produces hip...

journal_title：Neuroscience letters

authors： Sapolsky RM,Stein BA

更新日期：1989-02-13 00:00:00

abstract：:Seizures and death are the more important toxic consequences related to cocaine overdose. Some reports have shown that pharmacological manipulations in dopaminergic, serotonergic and noradrenergic systems alter the occurrence of cocaine-induced convulsions and death. Based on this fact, this work was performed to dete...

journal_title：Neuroscience letters

authors： Macêdo DS,Vasconcelos SM,Belchior LD,Santos RS,Viana GS,Sousa FC

更新日期：2004-05-27 00:00:00

abstract：:DNA fragmentation and activation of caspase-1, implicating involvement of apoptosis, have been reported in the spinal cord of amyotrophic lateral sclerosis (ALS) patients and transgenic mouse models of ALS. Because BH3-only members of the Bcl-2 family have pro-apoptotic activity, we examined the expression of the BH3-...

journal_title：Neuroscience letters

authors： Shinoe T,Wanaka A,Nikaido T,Kanazawa K,Shimizu J,Imaizumi K,Kanazawa I

更新日期：2001-11-09 00:00:00

abstract：:The effect of various ionic solutions microinjected into the nucleus tractus solitarii (NTS) on blood pressure, heart rate and respiration rate was investigated in urethane-anesthetized rats. Unilateral microinjection of solutions containing NaCl (154 mM), NaCl (154 mM) and KCl (2.8 mM) or NaNO3 (154 mM) into a restri...

journal_title：Neuroscience letters

authors： Lukovic L,de Jong W

更新日期：1990-03-02 00:00:00

abstract：:Foetal rat mesencephalic dopamine-containing tissue was transplanted into the lateral ventricle of mice previously subjected to a 6-OHDA lesion of dopaminergic nerve terminals in the corpus striatum. The graft recipients were immunosuppressed by subcutaneous injections of 15-deoxyspergualin (DSG). Four weeks postgraft...

journal_title：Neuroscience letters

authors： Zhou J,Date I,Sakai K,Yoshimoto Y,Furuta T,Asari S,Ohmoto T

更新日期：1993-11-26 00:00:00

abstract：:In order to determine which types of neuron in laminae I-III of the rat spinal dorsal horn contain the peptide galanin, pre-embedding immunocytochemistry with antiserum to galanin was combined with post-embedding detection of GABA- and glycine-like immunoreactivities. Sixty-eight galanin immunoreactive neurons in lami...

journal_title：Neuroscience letters

authors： Simmons DR,Spike RC,Todd AJ

更新日期：1995-03-03 00:00:00

abstract：:Ample evidence has been reported to show a probable contribution of orexin in the central cardiovascular regulation. Although cardiovascular and respiratory centers in the brain are located close to each other and are interconnected, the possible participation of orexin in respiratory regulation has not been fully doc...

journal_title：Neuroscience letters

authors： Zhang W,Fukuda Y,Kuwaki T

更新日期：2005-09-09 00:00:00

abstract：:The effects of various Flustra foliacea metabolites on different types of human neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes were investigated. Whereas most of the compounds tested had a small blocking effect, one of them, deformylflustrabromine, selectively increased the current ob...

journal_title：Neuroscience letters

authors： Sala F,Mulet J,Reddy KP,Bernal JA,Wikman P,Valor LM,Peters L,König GM,Criado M,Sala S

更新日期：2005-01-10 00:00:00