Abstract:
:Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There was no effect on serotonin turnover. Long-acting somatostatin analogues (D-Trp-8-somatostatin, SMS-201-995) had similar effects. These results suggest that somatostatin is involved in local regulation of striatal dopaminergic transmission and that it plays a role in regulation of dopamine release in the contralateral striatum.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Beal MF,Martin JBdoi
10.1016/0304-3940(84)90034-xsubject
Has Abstractpub_date
1984-02-24 00:00:00pages
271-6issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(84)90034-Xjournal_volume
44pub_type
杂志文章abstract::A series of experiments were designed to examine the potential induction of apoptosis by nitric oxide (NO) donors on cortical neuronal cell culture. A 24 h exposure of three different NO donors, 3-morpholinosydnonimine, S-nitroso-N-acetyl-penicillamine, and S-nitrosoglutathione, induced apoptosis as indicated by follo...
journal_title:Neuroscience letters
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doi:10.1016/0304-3940(96)12532-5
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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doi:10.1016/j.neulet.2005.08.032
更新日期:2006-01-02 00:00:00
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journal_title:Neuroscience letters
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doi:10.1016/j.neulet.2004.09.048
更新日期:2004-12-06 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章,随机对照试验
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更新日期:2013-08-26 00:00:00
abstract::Miyoshi myopathy (MM) is an autosomal recessive distal muscular dystrophy caused by mutations in the dysferlin gene (DYSF), a 150-kb gene on chromosome 2p13 that contains 55 coding exons. Many patients with MM harbour mutations in the DYSF gene, and most of these mutations are inherited from the patients' parents. Rec...
journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1999-05-14 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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更新日期:2002-01-18 00:00:00
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journal_title:Neuroscience letters
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更新日期:2020-06-11 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:
更新日期:1996-09-06 00:00:00
abstract::Urotensin I-like immunoreactivity (UILI), in different localization from that of corticotropin releasing factor-like immunoreactivity (CRFLI), in the goldfish retina has been demonstrated by means of radioimmunoassay, high-performance liquid chromatography (HPLC) and immunohistochemistry. Radioimmunoassay showed 350 +...
journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2005.12.025
更新日期:2006-04-10 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2010.06.057
更新日期:2010-08-30 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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更新日期:2012-10-24 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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更新日期:1995-01-02 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2011-02-01 00:00:00
abstract::Twenty-four hour patterns in somatostatin (SS)-like immunoreactivity (LI) within the suprachiasmatic nucleus (SCN) were determined by enzyme immunoassay in rats blinded by bilateral orbital enucleation or kept sighted under light-dark conditions. A remarkable circadian rhythm was found in the concentration of SS-LI in...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1991-08-05 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(92)90253-4
更新日期:1992-08-31 00:00:00
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journal_title:Neuroscience letters
pub_type: 临床试验,杂志文章
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更新日期:2005-06-10 00:00:00
abstract::Human subjects maintained isometric plantar or dorsal flexions of the ankle in a matching task. H-reflexes of different sizes were superimposed on the steady activity. The peak-to-peak amplitude of the reflexes was measured on the electromyogram (EMG) of the soleus muscle. The size of the corresponding muscle contract...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(89)90571-5
更新日期:1989-08-28 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2014.02.042
更新日期:2014-04-30 00:00:00
abstract::Estrogen was shown to promote neuronal survival against several neurotoxic insults including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen activated protein kinase/extracellular signal-regulated kinase (Mapk/Erk), phosphatidylinositol 3-kinase/Akt pathways and the upregulation of antiap...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2011.11.016
更新日期:2012-01-11 00:00:00
abstract::Considerable evidence suggests that low (picomolar) concentrations of the HIV-1 envelope glycoprotein gp120 induce neuronal cell death by stimulating the release of microglial toxins, which in turn activate N-methyl-D-aspartate (NMDA) receptors. Conversely, high (micromolar) concentrations of gp120 have been reported ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(00)00775-8
更新日期:2000-02-18 00:00:00
abstract::The localization of serotonin and non-serotonin-containing cell bodies in the interpeduncular nucleus of the rat that project to the hippocampal formation was studied using the technique of retrograde tracing of Granular Blue and immunohistochemistry on the same sections. The results indicate that the caudal magnocell...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90256-8
更新日期:1984-09-28 00:00:00