3-nitropropionic acid induces poly(ADP-ribosyl)ation and apoptosis related gene expression in the striatum in vivo.

abstract：:Physiological and radioligand binding studies have demonstrated the existence of 5-HT3 receptors in the enteric nervous system. In order to determine if the cloned 5-HT3 receptor subunit, 5-HT3R-A, was expressed in the enteric nervous system of rats, we have performed in situ hybridization with 33P-labeled cRNA antise...

journal_title：Neuroscience letters

authors： Johnson DS,Heinemann SF

更新日期：1995-01-16 00:00:00

abstract：:Effects of anxiety on perceptual-motor organisation of rhythmical forearm movements were examined using an interrupted time series design with staggered baselines. Participants were exposed to repeated baseline sessions interrupted with two anxiety-inducing sessions. Results showed that under moderate levels of anxiet...

journal_title：Neuroscience letters

authors： Court ML,Bennett SJ,Williams AM,Davids K

更新日期：2005-08-12 00:00:00

abstract：:Embryonic septal neurons were transplanted into the hippocampus of adult rats which had received lateral-ventricular administration of AF64A, a cholinergic neurotoxin, and the effects on hippocampal cholinergic activity were studied. One week after AF64A administration, we injected dissociated septal cell suspension i...

journal_title：Neuroscience letters

authors： Ikegami S,Nihonmatsu I,Hatanaka H,Takei N,Kawamura H

更新日期：1989-06-05 00:00:00

abstract：:It is well known that genetic variants play a critical role in the pathogenesis of Alzheimer's disease (AD). In 2009, a genome-wide association study (GWAS) demonstrated that a single nucleotide polymorphism (SNP), rs6656401, in complement receptor 1 (CR1) is significantly associated with late-onset Alzheimer's diseas...

journal_title：Neuroscience letters

authors： Jin C,Li W,Yuan J,Xu W,Cheng Z

更新日期：2012-10-03 00:00:00

abstract：:Cold defense mechanisms in mice are attenuated in the light phase during fasting, resulting in hypothermia. The present study examined whether specific neurons and areas in the SCN are related to the response. Mice were fasted over 47h or remained fed, during which they were placed at 20 or 27°C for 3h in the light or...

journal_title：Neuroscience letters

authors： Uchida Y,Tokizawa K,Nagashima K

更新日期：2014-09-05 00:00:00

abstract：:The objective of this study was to investigate whether berberine in Coptidis Rhizoma extract could be transported in primary cultured cerebral neurons and to study the uptake and transport behavior of berberine through the neurons. The present results showed that the uptake of berberine by the neurons increased linear...

journal_title：Neuroscience letters

authors： Wang X,Xing D,Wang W,Lei F,Su H,Du L

更新日期：2005-05-06 00:00:00

abstract：:The spinal nucleus of the bulbocavernosus (SNB) in rodents is a neuromuscular system consisting of lumbar motoneurons and the perineal muscles they innervate, the bulbocavernosus and levator ani. This system is present prenatally in both males and females but degenerates postnatally in females because of the lack of p...

journal_title：Neuroscience letters

authors： Smith MR,Hamson DK,Poort JE,Jordan CL,Breedlove SM

更新日期：2012-04-04 00:00:00

abstract：:Abnormal alteration of brain function is a characteristic complication of hepatic encephalopathy in both acute and chronic liver failure. Previous studies suggest that the pathogenesis of hepatic encephalopathy involves chronic glial edema with subsequent alteration of glioneuronal communication, N-methyl-d-aspartate ...

journal_title：Neuroscience letters

authors： Ohara K,Aoyama M,Fujita M,Sobue K,Asai K

更新日期：2009-09-22 00:00:00

abstract：:In urethane-chloralose anesthetized rats, the role of GABA(B) receptor in the commissural subnucleus of the nucleus tractus solitarii (commNTS) on the carotid chemoreceptor reflex was investigated. Microinjection of a GABA(B) agonist baclofen into the commNTS did not have any effects on arterial blood pressure (BP) or...

journal_title：Neuroscience letters

authors： Suzuki M,Tetsuka M,Endo M

更新日期：1999-01-22 00:00:00

abstract：:Rat cerebral explants were cultured in the presence or absence of the mitotic inhibitor cytosine arabinoside (AraC) to investigate whether reports of increased neurite outgrowth may be primarily related to a decreased incidence of fibroblastic-reactive microglial cells. Treated explants were exposed to AraC from 7 to ...

journal_title：Neuroscience letters

authors： Oorschot DE,Jones DG

更新日期：1989-07-31 00:00:00

abstract：:The effect of K-252a, a new alkaloid-like kinase inhibitor from the culture broth of Nocardiopsis sp., on the action of nerve growth factor on normal nerve cells was examined. Nerve cells were isolated from the dorsal root ganglia of chick embryo by trituration without using digesting enzymes, and were seeded on colla...

journal_title：Neuroscience letters

authors： Matsuda Y,Fukuda J

更新日期：1988-04-22 00:00:00

abstract：:Blood platelets are thought to be a useful peripheral model for investigating the central serotoninergic mechanisms associated with the serotonin transporter (SERT). On the other hand, an in vivo investigation of SERT in the human brain has been made possible by the development of several promising SPECT radioligands,...

journal_title：Neuroscience letters

authors： Uebelhack R,Franke L,Herold N,Plotkin M,Amthauer H,Felix R

更新日期：2006-10-09 00:00:00

abstract：:Infarct volume and immunoreactivities for trkB and trkC in rat brain were compared at 24 h after 90 min of transient middle cerebral artery occlusion (MCAO) between animal groups with or without neurotrophin-3 (NT-3, 10 microg/250 g animal). Treatment of rat brain with topical application of NT-3 significantly reduced...

journal_title：Neuroscience letters

authors： Zhang WR,Hayashi T,Wang JM,Sasaki C,Sakai K,Warita H,Shiro Y,Suenaga H,Ohmae H,Tsuji S,Itoh T,Nishimura O,Nagasaki H,Abe K

更新日期：1999-12-10 00:00:00

abstract：:Parkinson's disease (PD), caused by the decreased number of dopaminergic neurons in the substantia nigra, is identified as the second most familiar age-dependent neurodegenerative disease to the public. Long non-coding RNAs (lncRNAs) have been reported to participate in the development of PD. In our research, the expr...

journal_title：Neuroscience letters

authors： Xie Y,Zhang S,Lv Z,Long T,Luo Y,Li Z

更新日期：2021-01-06 00:00:00

abstract：:Agmatine (decarboxylated arginine) has been proposed as an endogenous ligand for non-adrenoceptor, imidazoline binding sites, but also binds to alpha 2-adrenoceptors. The interaction of agmatine with alpha 2-adrenoceptors was evaluated by studying the effect of agmatine on the firing rate of locus coeruleus (LC) neuro...

journal_title：Neuroscience letters

authors： Pineda J,Ruiz-Ortega JA,Martín-Ruiz R,Ugedo L

更新日期：1996-11-22 00:00:00

abstract：:A mini-symposium (chaired by L. Chal, Australia, P. Lembeck, Austria, J. Szolcsányi, Hungary and M. Zimmermann, F.R.G.) was held in Bad Nauheim, F.R.G. on June 29, 1990, under the sponsorship of the European Neuropeptide Club, which focussed on recent advances of research on sensory peptides and mechanism of action of...

journal_title：Neuroscience letters

authors： Maggi CA,Pierau FK

更新日期：1991-01-28 00:00:00

abstract：:Iontophoretically applied 2-azido photoaffinity analogues of adenosine 5'-triphosphate (ATP) and adenosine 5'-monophosphate (AMP) have been tested on rat cerebral cortical neurons. 2-Azido-AMP and 2-azido-ATP had a powerful depressant action on the spontaneous firing of cortical neurons. Both compounds were equipotent...

journal_title：Neuroscience letters

authors： Phillis JW

更新日期：1981-01-01 00:00:00

abstract：:Amphiphilic monomers and dimers of acetylcholinesterase (AChE) and hydrophilic tetramers of butyrylcholinesterase (BuChE) were released by extracting human meningioma with Tris-saline and Tris-saline-Triton X-100 buffers. The amphiphilic or hydrophilic behavior of the AChE and BuChE forms was assessed by sedimentation...

journal_title：Neuroscience letters

authors： Sáez-Valero J,Vidal CJ

更新日期：1995-08-04 00:00:00

abstract：:Whether or not chronic L-dopa treatment (100 mg/kg, intraperitoneally (i.p.), twice daily for 4 weeks) alters lipid peroxidation in the brain as an indicator of neuronal damage was examined in normal mice and mice in which catecholamine (CA) neurons had been injured previously by the administration of 6-hydroxydopamin...

journal_title：Neuroscience letters

authors： Ogawa N,Asanuma M,Kondo Y,Kawada Y,Yamamoto M,Mori A

更新日期：1994-04-25 00:00:00

abstract：:The association between (GT)n dinucleotide repeats in monoamine oxidase gene loci, monoamine oxidase A (MAOA) and B (MAOB), and Parkinson's disease (PD), Alzheimer's disease (AD), and Lewy body variant (LBV) of AD were determined. MAOA-GT polymorphisms were significantly associated with pure AD and LBV. MAOA-GT allele...

journal_title：Neuroscience letters

authors： Takehashi M,Tanaka S,Masliah E,Ueda K

更新日期：2002-07-19 00:00:00

abstract：:A pronounced decrease in dopamine content in both the striatum and the mesolimbic area was observed up to 120 days of age after treatment with 6-hydroxydopamine (100 micrograms, intracisternally) following desipramine pretreatment (20 mg/kg, i.p.) at the 5th postnatal day. In the 6-hydroxydopamine-treated rats, Met-en...

journal_title：Neuroscience letters

authors： Kurumaji A,Takashima M,Watanabe S,Takahashi K

更新日期：1988-04-22 00:00:00

abstract：:Kainic acid administration induces status epilepticus seizures in the rat which damage CA1 and CA3 hippocampal neurons. Rats made hypoglycemic prior to seizure had enhanced volumes of damage, when compared to normo- or hyperglycemic rats. The mild hypoglycemia was not in the range which, itself, typically produces hip...

journal_title：Neuroscience letters

authors： Sapolsky RM,Stein BA

更新日期：1989-02-13 00:00:00

abstract：:To investigate whether the xenon-induced inhibition of the transient receptor potential vanilloid type 1 (TRPV1) ion channel in rat dorsal root ganglion (DRG) neurons reduces nociceptive processing, we examined the effect of xenon in reducing the release of calcitonin gene-related peptide (CGRP) from those neurons. We...

journal_title：Neuroscience letters

authors： Calcott G,White JP,Nagy I

更新日期：2011-07-20 00:00:00

abstract：:Estrogen levels in rats are positively correlated with enhanced memory function and hippocampal dendritic spine density. There is much less work on the long-term effects of estradiol manipulation in preadolescent rats. The present work examined how injections of estradiol during postnatal days 19-22 (p19-22; preadoles...

journal_title：Neuroscience letters

authors： Wartman BC,Keeley RJ,Holahan MR

更新日期：2012-10-24 00:00:00

abstract：:There is considerable evidence linking both genotype and coagulopathy to vascular complications of traumatic brain injury (TBI) and other cerebral insults. The authors explored a possible connection between the apolipoprotein E (Apo E) genotype, coagulopathy and intravascular microthombosis (IMT) in TBI. The predicted...

journal_title：Neuroscience letters

authors： Stein SC,Graham DI,Chen XH,Dunn L,Smith DH

更新日期：2005-10-14 00:00:00

abstract：:In an attempt to understand the change of superoxide dismutase (SOD) in tumor cells by hypoxia and hypoxia-normoxia exposure, the present study performed an in vitro investigation using rat glioma cell line in culture. Hypoxia was induced by an incubation with nitrogen gas for 15 h followed the normoxia exposure with ...

journal_title：Neuroscience letters

authors： Chang CK,Tsai CY,Lin LS,Jou SB,Liao SS,Cheng JT

更新日期：1997-08-29 00:00:00

abstract：:The actions of noradrenaline (NA) in the substantia gelatinosa (SG) are important for their antinociceptive effects. In order to identify the possible mechanisms underlying NA actions in the SG of trigeminal subnucleus caudalis (Vc), the direct membrane effects were examined by gramicidin-perforated patch clamp record...

journal_title：Neuroscience letters

authors： Han SK,Park JR,Park SA,Chun SW,Lee JC,Lee SY,Ryu PD,Park SJ

更新日期：2007-01-10 00:00:00

abstract：:Pineal serotonin (5-HT), 5-hydroxyindole-acetic acid (5-HIAA), norepinephrine (NE), epinephrine (E) and adrenal corticosterone, NE and E contents were measured spectrofluorometrically 5, 15, 30 and 60 min after insulin treatment to induce hypoglycemic stress. In the pineal gland, hypoglycemic stress caused dramatic de...

journal_title：Neuroscience letters

authors： Mahata SK

更新日期：1991-01-02 00:00:00

abstract：:In this study, we aimed to investigate whether self-reported mild traumatic brain injury (mTBI) was associated with decreased AD-vulnerable cortical thickness, and to assess the relationship between AD-vulnerable cortical thickness and AD-related biomarker in the Alzheimer's Disease Neuroimaging Initiative subjects. W...

journal_title：Neuroscience letters

authors： Wang ML,Wei XE,Yu MM,Li PY,Li WB,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2017-08-10 00:00:00

abstract：:An optimized clinical functional magnetic resonance imaging (fMRI) protocol with a total scanning time of 8 min is presented that localizes Broca's and Wernicke's areas robustly and determines hemispheric dominance. Language function was visualized using two different sentence generation (SG) and word generation (WG) ...

journal_title：Neuroscience letters

authors： Stippich C,Mohammed J,Kress B,Hähnel S,Günther J,Konrad F,Sartor K

更新日期：2003-07-31 00:00:00