Nitric oxide induces cultured cortical neuron apoptosis.

Abstract:

:A series of experiments were designed to examine the potential induction of apoptosis by nitric oxide (NO) donors on cortical neuronal cell culture. A 24 h exposure of three different NO donors, 3-morpholinosydnonimine, S-nitroso-N-acetyl-penicillamine, and S-nitrosoglutathione, induced apoptosis as indicated by following histological (cellular and nuclear morphology) and biochemical markers (DNA oligonucleosomal fragmentation and protection by protein synthesis inhibitor).

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Palluy O,Rigaud M

doi

10.1016/0304-3940(96)12532-5

subject

Has Abstract

pub_date

1996-04-12 00:00:00

pages

1-4

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304394096125325

journal_volume

208

pub_type

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