Expression of a developmentally-regulated neuron-specific isoform of the neurofibromatosis 1 (NF1) gene.

abstract：:The intracellular stress-induced proteins provide protection against toxic insults. Here, a 60,000-Da heat shock 60 (hsp60)-like protein was detected, with five different antibodies, in conditioned media derived from rat cortical astrocytes and a human neuroblastoma cell line. Extracellular neuroblastoma hsp60-like im...

journal_title：Neuroscience letters

authors： Bassan M,Zamostiano R,Giladi E,Davidson A,Wollman Y,Pitman J,Hauser J,Brenneman DE,Gozes I

更新日期：1998-06-26 00:00:00

abstract：:Polypeptides phosphorylated in vivo in Drosophila mutants defective in learning and memory, were characterized by polyacrylamide gel electrophoresis of subcellular fractions obtained by phase partitioning in Triton X-114 [3]. In the mutants turnip, dunce and Shaker, one or more bands at a molecular weight range of 50-...

journal_title：Neuroscience letters

authors： Buxbaum JD,Dudai Y

更新日期：1989-10-09 00:00:00

abstract：:Previous studies indicate that the locus coeruleus (LC) can be divided into sub-areas depending upon dominant efferent projection zones. Ascending projections to the forebrain originate within the dorsal half and projections to the spinal cord and the cerebellum course from the ventral half of the LC. Using Sprague-Da...

journal_title：Neuroscience letters

authors： Babstock D,Malsbury CW,Harley CW

更新日期：1997-03-21 00:00:00

abstract：:The epsilon4 allele of the apolipoprotein E gene (APOE) has repeatedly been associated with increased risk for Alzheimer's disease (AD). Bullido and colleagues recently identified a polymorphism in the promoter region of the APOE gene (-491A/T) and found that -491A homozygosity predicted AD independently of APOE epsil...

journal_title：Neuroscience letters

authors： Town T,Paris D,Fallin D,Duara R,Barker W,Gold M,Crawford F,Mullan M

更新日期：1998-08-14 00:00:00

abstract：:Regeneration of reduced nicotinamide adenine dinucleotide phosphate (NADPH) is essential for the activity of glutathione redox cycling during cellular peroxide detoxification. In order to test for a function of astroglial glycogen to serve as endogenous precursor for glucose-6-phosphate, the substrate for the regenera...

journal_title：Neuroscience letters

authors： Rahman B,Kussmaul L,Hamprecht B,Dringen R

更新日期：2000-09-01 00:00:00

abstract：:Synaptotagmin I (Syt I), a possible Ca(2+) sensor for neurotransmitter release, was suggested to be involved in neurite outgrowth of chick dorsal root ganglion (DRG) neurons, based on introduction of the antibody against the C2A domain into cells via mechanical lesions. Recently, however, the functional block antibody...

journal_title：Neuroscience letters

authors： Fukuda M,Mikoshiba K

更新日期：2000-12-01 00:00:00

abstract：:Neuronal density, neuron size, and the number of neurons under 1 mm2 of cerebral cortical surface area were measured in the right pre-frontal cortex of Albert Einstein and five elderly control subjects. Measurement of neuronal density used the optical dissector technique on celloidin-embedded cresyl violet-stained sec...

journal_title：Neuroscience letters

authors： Anderson B,Harvey T

更新日期：1996-06-07 00:00:00

abstract：:We recently described dextran derivatives (RGTA) which stimulate tissue repair in several in vivo models. One of them, RGTA11, has been shown to accelerate crush-induced regeneration and reinnervation of rat EDL and Soleus muscles. In this study we wanted to know if RGTA11 alters the pattern of myosin heavy chain expr...

journal_title：Neuroscience letters

authors： Aamiri A,Butler-Browne GS,Martelly I,Barritault D,Gautron J

更新日期：1995-12-15 00:00:00

abstract：:Presenilin1 (PSEN1) 1143T and G384A mutations give rise to severe early-onset Alzheimer's disease in two extensively studied Belgian families. In the present study, we examined the effect of PSEN1 1143T and G384A mutations on tau phosphorylation in human SH-SY5Y and mouse Neuro-2a neuroblastoma cell lines that were tr...

journal_title：Neuroscience letters

authors： Julliams A,Vanderhoeven I,Kuhn S,Van Broeckhoven C,De Jonghe C

更新日期：1999-07-09 00:00:00

abstract：:In the caudal postcentral finger region near or in the anterior bank of the intraparietal sulcus of alert monkeys, we found neurons that were activated selectively by the contact of the hand to certain common objects such as bottle brushes, acrylic plates, parts of the stabilized monkey's chair, etc. All of these neur...

journal_title：Neuroscience letters

authors： Iwamura Y,Tanaka M,Hikosaka O,Sakamoto M

更新日期：1995-02-17 00:00:00

abstract：:DNA variation at the FGF20 gene has been associated with Parkinson's disease (PD). In particular, SNP rs12720208 in the 3' untranslated region (3' UTR) was linked to PD-risk through a mechanism that would implicate a differential binding to microRNA-433 (miR-433). The reduction of the affinity of miR-433 to the 3' UTR...

journal_title：Neuroscience letters

authors： de Mena L,Cardo LF,Coto E,Miar A,Díaz M,Corao AI,Alonso B,Ribacoba R,Salvador C,Menéndez M,Morís G,Alvarez V

更新日期：2010-07-19 00:00:00

abstract：:The occurrence and distribution of nociceptin, a 17-amino acid peptide with structural similarity to dynorphin A, and its receptor, opioid receptor-like-1 (ORL1) receptor, were investigated in the guinea-pig sympathetic nervous system by means of immunohistochemistry and reverse transcription-polymerase chain reaction...

journal_title：Neuroscience letters

authors： Kummer W,Fischer A

更新日期：1997-09-26 00:00:00

abstract：:A dose-dependent loss of vanilloid receptors (specific [3H]resiniferatoxin binding sites) was found in sensory ganglia of rats 24 h after s.c. administration of resiniferatoxin (RTX), an ultrapotent capsaicin analog. This receptor loss displayed an ED50 of 30 micrograms/kg both in dorsal root and trigeminal ganglia; t...

journal_title：Neuroscience letters

authors： Szallasi A,Blumberg PM

更新日期：1992-06-08 00:00:00

abstract：:Gap junctions between neurons contribute to synchronous neuronal firing and may play a role in the pathophysiology of epilepsy. We examined the expression of a number of gap junction subunits, including the neuronal gap junction forming protein connexin36 (Cx36), in the hippocampus at various time points following an ...

journal_title：Neuroscience letters

authors： McCracken CB,Roberts DC

更新日期：2006-09-11 00:00:00

abstract：:Recent findings from our and other laboratories indicate that cell cycle-related phenomena may play a key role in the formation of Alzheimer-type pathology and neuronal cell death in both Alzheimer's and cerebro-vascular diseases. In this study we examine the expression patterns of cyclins A, B1, D1 and E in neuronal ...

journal_title：Neuroscience letters

authors： Smith MZ,Nagy Z,Esiri MM

更新日期：1999-08-13 00:00:00

abstract：:Localized moderate cooling (+10 degrees C) of the anterior and ventral part of the raphe dorsalis induced cortical synchronization and ponto-geniculo-occipital (PGO) waves followed sometimes by paradoxical sleep. Cooling the region of the raphe magnus produced cortical arousal. After depletion of brain 5-hydroxytrypta...

journal_title：Neuroscience letters

authors： Cespuglio R,Walker E,Gomez ME,Musolino R

更新日期：1976-11-01 00:00:00

abstract：:The dichotic listening test is non-invasive behavioural technique to study brain lateralization and it has been shown, that its results can be systematically modulated by varying stimulation properties (bottom-up effects) or attentional instructions (top-down effects) of the testing procedure. The goal of the present ...

journal_title：Neuroscience letters

authors： Hugdahl K,Westerhausen R,Alho K,Medvedev S,Hämäläinen H

更新日期：2008-01-24 00:00:00

abstract：:The superoxide (O2.-) scavenging activity and the neuroprotective effects of pterin-6-aldehyde (P6A), a xanthine oxidase inhibitor, were examined and compared with those of alpha-phenyl-N-tert-butyl nitrone (PBN), a spin trapping agent. The scavenging activity of P6A was more potent than that of PBN by 150-fold in neu...

journal_title：Neuroscience letters

authors： Mori H,Arai T,Ishii H,Adachi T,Endo N,Makino K,Mori K

更新日期：1998-01-30 00:00:00

abstract：:The 22Na+ efflux stimulated by selected agonists of the 4 excitatory amino acid receptors, previously detected in the striatum, has been studied on 22Na+-preloaded slices prepared from 10 major areas of the rat brain. All brain areas were found to be sensitive, albeit to varying extents, to excitatory amino acids. The...

journal_title：Neuroscience letters

authors： Luini A,Goldberg O,Teichberg VI

更新日期：1983-11-11 00:00:00

abstract：:Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

journal_title：Neuroscience letters

authors： Peters J,Daum I

更新日期：2009-05-01 00:00:00

abstract：:The purpose of the present experiment was to investigate the effect of vision on postural control following a lower limbs muscular fatigue. Ten adult males were asked to maintain a single leg upright posture as immobile as possible in two conditions of no-fatigue and fatigue of the calf muscles. This muscles fatigue w...

journal_title：Neuroscience letters

authors： Vuillerme N,Nougier V,Prieur JM

更新日期：2001-08-03 00:00:00

abstract：:In 16 rats, the extensor digitorum longus (EDL) - a fast muscle - was grafted, complete with its innervation, into the bed of the (removed) soleus - a slow muscle. Following the transposition, performed on one side only, EDL recovered and showed the contraction time of the contralateral EDL that served as control. How...

journal_title：Neuroscience letters

authors： Gutmann E

更新日期：1976-07-01 00:00:00

abstract：:The objective of this study was to determine if yohimbine, a central norepinephrine enhancing drug, increases cortico-motoneuronal excitability in intact humans. Transcranial magnetic stimulation was used to assess excitability of the motor system reflected in the parameters motor threshold, recruitment curve, intraco...

journal_title：Neuroscience letters

authors： Plewnia C,Bartels M,Cohen L,Gerloff C

更新日期：2001-07-06 00:00:00

abstract：:Calcium antagonists inhibit both the Ca2(+)-dependent and -independent release of endogenous glutamate from intact synaptosomes. In the present study, the inhibitory potency of several different classes of calcium antagonists were determined under conditions that control for an effect of these compounds on the Ca2(+)-...

journal_title：Neuroscience letters

authors： Terrian DM,Dorman RV,Gannon RL

更新日期：1990-11-13 00:00:00

abstract：:This study examined the ERP (event-related potential) correlates of categorization processing in brand extension with irrelative task. Participants faced two sequential stimuli in a pair consisting of a soft drink brand name (S1) and a product name (S2) which comprised two categories: beverage (typical product of the ...

journal_title：Neuroscience letters

authors： Wang X,Ma Q,Wang C

更新日期：2012-09-06 00:00:00

abstract：:Many studies have shown that acupuncture can contribute to the biochemical balance in the central nervous system and maintenance or recovery of homeostasis. It is well known that chronic administration of ethanol may produce depletion or sensitization of extracellular dopamine levels in the nucleus accumbens. The pres...

journal_title：Neuroscience letters

authors： Zhao RJ,Yoon SS,Lee BH,Kwon YK,Kim KJ,Shim I,Choi KH,Kim MR,Golden GT,Yang CH

更新日期：2006-02-27 00:00:00

abstract：:A quantitative analysis of cytochrome oxidase (CO) activity in histochemically stained sections of rat brain was developed using tissue standards and computerized image processing. Standards of brain paste containing known amounts of CO were cryosectioned and stained under the same conditions as brain sections. The gr...

journal_title：Neuroscience letters

authors： Gonzalez-Lima F,Garrosa M

更新日期：1991-02-25 00:00:00

abstract：:Recent studies suggested that statins have anti-inflammatory effects beyond their lipid-lowering properties. In the present study, we sought to investigate whether rosuvastatin could alleviate morphine tolerance by attenuating the glia mediated neuroinflammation in the spinal cord. Using a rat model of L5 spinal nerve...

journal_title：Neuroscience letters

authors： Li W,Li Y,Zhu S,Ji Q,Shu Y,Zhang L,Liu J

更新日期：2015-01-01 00:00:00

abstract：:We previously reported that corticotropin-releasing factor (CRF) increased neuronal excitability specifically in type II neurons of the dorsolateral part of the bed nucleus of the stria terminalis (dlBNST). Because the majority of type II dlBNST neurons are thought to be GABAergic interneurons, at least a portion of w...

journal_title：Neuroscience letters

authors： Nagano Y,Kaneda K,Maruyama C,Ide S,Kato F,Minami M

更新日期：2015-07-23 00:00:00

abstract：:We compared the modulation of GABA (gamma-aminobutyric acid)-activated currents by benzodiazepines in recombinant GABAA receptors containing either one of two alpha subunits, alpha 1 or alpha 6. Lüddens et al. (Nature, 346 (1990) 648-651) have previously demonstrated that the alpha 6 subunit is part of a cerebellar re...

journal_title：Neuroscience letters

authors： Kleingoor C,Ewert M,von Blankenfeld G,Seeburg PH,Kettenmann H

更新日期：1991-09-16 00:00:00