Abstract:
:Localized moderate cooling (+10 degrees C) of the anterior and ventral part of the raphe dorsalis induced cortical synchronization and ponto-geniculo-occipital (PGO) waves followed sometimes by paradoxical sleep. Cooling the region of the raphe magnus produced cortical arousal. After depletion of brain 5-hydroxytryptamine (5-HT) by para-chlorophenylalanine, cooling the raphe dorsalis resulted in muscle atonia and bursts of high frequency PGO waves but not in cortical synchronization. Following restoration of brain 5-HT by intravenous administration of 5-hydroxytryptophan, cooling again produced cortical synchronization and PGO waves as in the control experiments, but with a diminishing efficacy during repetitive cooling episodes.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Cespuglio R,Walker E,Gomez ME,Musolino Rdoi
10.1016/0304-3940(76)90077-xsubject
Has Abstractpub_date
1976-11-01 00:00:00pages
221-7issue
4eissn
0304-3940issn
1872-7972pii
0304-3940(76)90077-Xjournal_volume
3pub_type
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