Cardiovascular actions of neuropeptide Y in the hypothalamic paraventricular nucleus of conscious Long Evans and Brattleboro rats.

Abstract:

:The central cardiovascular effects of neuropeptide Y (NPY) have been investigated by microinjection of the peptide into the hypothalamic paraventricular nucleus (PVN) of conscious rats. NPY (100 ng) elicited a significant bradycardia in both Long Evans (control) rats (-27 +/- beats/min) and vasopressin-deficient Brattleboro rats (-19 +/- 6 beats/min). There was a slight fall in systolic blood pressure in both strains which was significant only in Long Evans rats. A higher dose of NPY (1000 ng) had no significant effect on blood pressure or heart rate, but produced a marked behavioural response characterized by initiation of foraging behaviour. These results provide further support for a role for NPY in central cardiovascular regulation, but provide no evidence of an indispensable involvement of vasopressin-containing pathways in the observed responses.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Harland D,Bennett T,Gardiner SM

doi

10.1016/0304-3940(88)90358-8

subject

Has Abstract

pub_date

1988-02-29 00:00:00

pages

239-43

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(88)90358-8

journal_volume

85

pub_type

杂志文章
  • Relation between asymmetry of prefrontal cortex activities and the autonomic nervous system during a mental arithmetic task: near infrared spectroscopy study.

    abstract::The present study evaluated the relationship between asymmetry of the prefrontal cortex activity and the automatic nervous system (ANS) response during a mental arithmetic (MA) task. Employing near infrared spectroscopy, we compared cerebral blood oxygenation changes in the right and left prefrontal cortices during a ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.07.076

    authors: Tanida M,Sakatani K,Takano R,Tagai K

    更新日期:2004-10-07 00:00:00

  • Morphological and conduction changes in the sciatic nerve of spontaneously hypertensive rats.

    abstract::The morphology and function of sciatic nerve were investigated in spontaneously hypertensive rats (SHR), either control or hydralazine-treated, and in normotensive Wistar Kyoto rats of 6 months of age. In control SHR decreased percentages of class I fibers (20-15 microm in diameter), of axonal NFP-H 200 kDa neurofilam...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.03.014

    authors: Tomassoni D,Traini E,Vitaioli L,Amenta F

    更新日期:2004-05-20 00:00:00

  • A substance P mediated pathway contributes to 6-hydroxydopamine induced cell death.

    abstract::The neurotoxin 6-hydroxydopamine (6-OHDA) is used to induce dopaminergic cell death, resulting in insufficient striatal dopamine content in the basal ganglia and motor dysfunction typical of Parkinson's disease. Dopamine induces release of the neuropeptide substance P (SP) within the substantia nigra, whereas SP is ab...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.06.057

    authors: Thornton E,Tran TT,Vink R

    更新日期:2010-08-30 00:00:00

  • The role of protein kinase CK2 in skeletal muscle: Myogenesis, neuromuscular junctions, and rhabdomyosarcoma.

    abstract::For the first time, a review article focuses exclusively on the role of the protein kinase CK2 in mono- and poly-nucleated mammalian skeletal muscle cells. While CK2, a pleiotropic serine/threonine kinase was originally thought to phosphorylate mainly casein, later evidence found glycogen phosphorylase and glycogen sy...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2020.135001

    authors: Hashemolhosseini S

    更新日期:2020-06-11 00:00:00

  • A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.

    abstract::Many studies have shown that minocycline, an antibacterial tetracycline, suppresses experimental pain. While minocycline's positive effects on pain resolution suggest that clinical use of such drugs may prove beneficial, minocycline's antibiotic actions and divalent cation (Ca(2+); Mg(2+)) chelating effects detract fr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.03.014

    authors: Bastos LF,Godin AM,Zhang Y,Jarussophon S,Ferreira BC,Machado RR,Maier SF,Konishi Y,de Freitas RP,Fiebich BL,Watkins LR,Coelho MM,Moraes MF

    更新日期:2013-05-24 00:00:00

  • Lack of association of interleukin-1beta polymorphism with Alzheimer's disease in the Jewish population.

    abstract::A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes, including the activation of inflammatory cytokines. We performed a case-control association study between sporadic AD patients and the exon 5 position +3953 polymorphism in the potent pro-inflammatory cyt...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.03.063

    authors: Rosenmann H,Meiner Z,Dresner-Pollak R,Kahana E,Aladjem Z,Grenader T,Wertman E,Abramsky O

    更新日期:2004-06-10 00:00:00

  • Immunocytochemical localization of endopeptidase-24.11 in the nucleus tractus solitarius of the rat brain.

    abstract::Recently, it has been hypothesized that the N-terminal portion of substance P (SP), SP(1-7), which results from the action of endopeptidase 24.11 (EC3.4.24.11), could be involved in mediating the depressor effects of baroreceptor afferent activation via its action on cells in the nucleus tractus solitarius (NTS). In t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90117-r

    authors: Lasher RS,Lutz EM,Mulholland F,Sanderson R,Stewart JM,Bublitz C

    更新日期:1990-09-04 00:00:00

  • Constitutive expression of mRNA for the same choline acetyltransferase as that in the nervous system, an acetylcholine-synthesizing enzyme, in human leukemic T-cell lines.

    abstract::Both muscarinic and nicotinic acetylcholine (ACh) receptors are known to be present on the surface of lymphocytes. We have shown that variable amounts of ACh are detectable in the blood of various mammals including humans, and a major portion of blood ACh is localized in circulating mononuclear leukocytes in humans. I...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00921-5

    authors: Fujii T,Tajima S,Yamada S,Watanabe Y,Sato KZ,Matsui M,Misawa H,Kasahara T,Kawashima K

    更新日期:1999-01-08 00:00:00

  • Noxious stimulus-induced increase in spinal prostaglandin E2 is noradrenergic terminal-dependent.

    abstract::Prostaglandins (PGs) were measured in perfusate from the lumbar intrathecal (IT) space of pentobarbital anaesthetized rats. The level of PGE2, but not of PGF2 alpha or 6-keto PGF1 alpha, was increased by immersion of a hindpaw in water at a noxious temperature (50 degrees C). No increase in PGE2 was produced by non-no...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90464-k

    authors: Coderre TJ,Gonzales R,Goldyne ME,West J,Levine JD

    更新日期:1990-07-31 00:00:00

  • Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-beta-peptides.

    abstract::Acetylcholinesterase (AChE) colocalizes with amyloid-beta peptide (A beta) deposits present in the brain of Alzheimer's patients. Recent studies showed that A beta 1-40 can adopt two different conformational states in solution (an amyloidogenic conformer, A beta ac, and a non-amyloidogenic conformer, A beta nac) which...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)12127-c

    authors: Alvarez A,Bronfman F,Pérez CA,Vicente M,Garrido J,Inestrosa NC

    更新日期:1995-12-01 00:00:00

  • Tetraethylammonium-induced long-term potentiation in layer V horizontal connections of rat motor cortex.

    abstract::The possibility for the induction of long-lasting synaptic plasticity by the potassium channel blocker tetraethylammonium (TEA) was investigated in adult rat motor cortex in vitro. Brief application of TEA (25 mM) resulted in a long-term potentiation (LTP(K)) of field potentials evoked in layer V intralaminar connecti...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01715-8

    authors: Jagodzinski P,Hess G

    更新日期:2001-01-26 00:00:00

  • NGP1-01, a lipophilic polycyclic cage amine, is neuroprotective in focal ischemia.

    abstract::NGP1-01, a member of the pentacycloundecylamine cage compound family, was recently shown to exhibit both NMDA receptor channel blocking and L-type calcium channel antagonism activity. In the present study, focal ischemia was induced in mice by permanent middle cerebral artery occlusion (MCAO) to test for potential neu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.03.042

    authors: Mdzinarishvili A,Geldenhuys WJ,Abbruscato TJ,Bickel U,Klein J,Van der Schyf CJ

    更新日期:2005-07-22 00:00:00

  • Activation of substantia gelatinosa by midbrain reticular stimulation demonstrated with 2-deoxyglucose in the rat spinal cord.

    abstract::The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map the descending effects of midbrain reticular stimulation on the rat cervical spinal cord. The stimulation evoked consistently a defensive 'freezing' reaction as well as a large and highly localized increase in 2-DG uptake in the substantia gelatino...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90283-1

    authors: Gonzalez-Lima F

    更新日期:1986-04-24 00:00:00

  • Adaptation of postural response to voluntary arm raises during locomotion in humans.

    abstract::Adaptation of the response to voluntary rapid arm flexion during 3 phases of the step cycle in humans are examined. The onset of arm movement was similar to the standing condition and was unaffected by the phase of the step cycle. The locomotor cycle in contrast was altered. These changes improved the stability of the...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90512-4

    authors: Patla AE

    更新日期:1986-08-04 00:00:00

  • Design principles of electrical synaptic plasticity.

    abstract::Essentially all animals with nervous systems utilize electrical synapses as a core element of communication. Electrical synapses, formed by gap junctions between neurons, provide rapid, bidirectional communication that accomplishes tasks distinct from and complementary to chemical synapses. These include coordination ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2017.09.003

    authors: O'Brien J

    更新日期:2019-03-16 00:00:00

  • Sensory supplementation system based on electrotactile tongue biofeedback of head position for balance control.

    abstract::The present study aimed at investigating the effects of an artificial head position-based tongue-placed electrotactile biofeedback on postural control during quiet standing under different somatosensory conditions from the support surface. Eight young healthy adults were asked to stand as immobile as possible with the...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.11.049

    authors: Vuillerme N,Pinsault N,Chenu O,Demongeot J,Payan Y,Danilov Y

    更新日期:2008-02-06 00:00:00

  • Vasoactive intestinal polypeptide-immunoreactive nerves in the kidney.

    abstract::Nerve fibers immunoreactive for vasoactive intestinal polypeptide (VIP) were demonstrated by immunocytochemistry in the dog and rat kidney. They were seen in association with the renal artery and its branches. In the dog, VIP-immunoreactive fibers were rarely seen close to small blood vessels suggestive of arterioles....

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90199-4

    authors: Barajas L,Sokolski KN,Lechago J

    更新日期:1983-12-30 00:00:00

  • Prickle promotes neurite outgrowth via the Dishevelled dependent pathway in C1300 cells.

    abstract::Murine Prickle1 and Prickle2 belong to the planar cell polarity genes. Prickle2 but not Prickle1 gene expression was induced in C1300 neuroblastoma cells during neurite-like process formation induced by retinoic acid (RA). Over-expression of Prickle1 or Prickle2 in C1300 cells induced striking neurite-like process for...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.09.050

    authors: Fujimura L,Watanabe-Takano H,Sato Y,Tokuhisa T,Hatano M

    更新日期:2009-12-18 00:00:00

  • Transient retinal fibers to the inferior colliculus in the newborn albino rat.

    abstract::Transient retinal fibers to the inferior colliculus were found in newborn albino rats. After horseradish peroxidase injection into the vitreous cavity of rats of 1-3 days of age, anterogradely-labeled retinal fibers were traced through the superior colliculus to the inferior colliculus. These retinal fibers to the inf...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90496-2

    authors: Kato T

    更新日期:1983-05-27 00:00:00

  • Induction of Fos-immunoreactivity in prolactin-like containing neurons of the rat lateral hypothalamus after insulin treatment.

    abstract::The role of the lateral hypothalamus (LHT) in the regulation of feeding behavior has long been established. The major contribution of LHT glucose-sensitive neurons, activated by low glucose concentration, is well accepted. Two peptidergic neuron populations, whose perikarya are exclusively located within this area, ha...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90404-9

    authors: Bahjaoui-Bouhaddi M,Fellmann D,Bugnon C

    更新日期:1994-02-28 00:00:00

  • Simulation of the geomagnetic field experienced by the International Space Station in its revolution around the Earth: effects on psychophysiological responses to affective picture viewing.

    abstract::There is evidence suggesting that exposure to an abnormal magnetic environment may produce psychophysiological effects related to abnormalities in responses to stress. This may be of relevance for space medicine where astronauts are exposed to a magnetic field different from that exerted by the Earth. Aim of this stud...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.neulet.2006.02.045

    authors: Del Seppia C,Mezzasalma L,Messerotti M,Cordelli A,Ghione S

    更新日期:2006-06-12 00:00:00

  • Evidence for spinal dorsal horn hyperexcitability in rats following sustained morphine exposure.

    abstract::Repeated or sustained exposure to opioids can not only induce analgesia but also long lasting enhancements in pain sensitivity, a phenomenon reported clinically and in animals. In rats, opioid-induced abnormal pain can be readily measured following continued delivery of morphine and the recruitment of descending facil...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.08.027

    authors: Suzuki R,Porreca F,Dickenson AH

    更新日期:2006-10-23 00:00:00

  • Cell that are O4 antigen-positive and O1 antigen-negative differentiate into O1 antigen-positive oligodendrocytes.

    abstract::In freshly dissociated viable cells of early postnatal mouse cerebellum, O1 antigen-positive oligodendrocytes have been eliminated by complement dependent immunocytolysis. Before seeding residual cells in culture, O4 antigen-positive cells were immunolabeled by O4 antibody which had been directly conjugated with rhoda...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(82)90351-2

    authors: Sommer I,Schachner M

    更新日期:1982-04-16 00:00:00

  • NRF2/HO-1 activation via ERK pathway involved in the anti-neuroinflammatory effect of Astragaloside IV in LPS induced microglial cells.

    abstract::The anti-neuroinflammatory effect of Astragaloside IV (ASI) has been reported, but its underlying mechanisms are unclear. This study is further to explore the underlying mechanism of ASI on anti-neuroinflammatory effect in LPS induced microglia cells. The result showed ASI significantly reduced the production of infla...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.12.039

    authors: Li C,Yang F,Liu F,Li D,Yang T

    更新日期:2018-02-14 00:00:00

  • Synaptic communication of cellular oscillations in the rat suprachiasmatic neurons.

    abstract::Circadian firing rhythms of cultured rat suprachiasmatic nucleus were measured simultaneously from 4-8 neurons by using a multi-electrode dish and neuronal interactions were examined by a cross-correlation analysis of spontaneous action potentials. Functional connections were detected in the neuron pairs showing synch...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01558-5

    authors: Honma S,Shirakawa T,Nakamura W,Honma K

    更新日期:2000-11-17 00:00:00

  • Increased susceptibility of brain slices from carbonic anhydrase II-deficient mice to low [Mg2+]O-induced seizures.

    abstract::Brain pH is thought to be an influential factor in determining susceptibility to seizures. We compared the susceptibility of brain slices from carbonic anhydrase II (CA II)-deficient mice to epileptiform activity induced by low extracellular [Mg2+], with slices from normal littermates, both bathed in artificial cerebr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(96)12515-5

    authors: Velísek L,Moshé SL,Stanton PK

    更新日期:1996-04-05 00:00:00

  • Prefrontal gray matter increases in healthy individuals after lithium treatment: a voxel-based morphometry study.

    abstract::The objective of this study was to test the hypothesis that 4 weeks of lithium administration would be associated with changes in brain gray and white matter volumes in healthy individuals. Thirteen right-handed healthy volunteers (6 females, mean age=25.9+/-10.0 years) were studied. 3D SPGR MRIs (TR=25 ms, TE=5 ms, s...

    journal_title:Neuroscience letters

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.neulet.2007.09.074

    authors: Monkul ES,Matsuo K,Nicoletti MA,Dierschke N,Hatch JP,Dalwani M,Brambilla P,Caetano S,Sassi RB,Mallinger AG,Soares JC

    更新日期:2007-12-11 00:00:00

  • Nerve cell bodies and small ganglia in the connective tissue stroma of human submandibular glands.

    abstract::The objective of the study was to investigate the presence and distribution of nerve cell bodies and small ganglia in the stroma of human submandibular gland. A retrospective immunohistochemical study in 13 human submandibular glands, fixed in neutral buffered formalin and embedded in paraffin wax, was undertaken. Six...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.03.045

    authors: Tosios KI,Nikolakis M,Prigkos AC,Diamanti S,Sklavounou A

    更新日期:2010-05-07 00:00:00

  • Traumatic brain injury-induced expression and phosphorylation of pyruvate dehydrogenase: a mechanism of dysregulated glucose metabolism.

    abstract::Dysregulated brain glucose metabolism and lactate accumulation are seen following traumatic brain injury (TBI). The underlying molecular mechanism is poorly understood. Pyruvate dehydrogenase (PDH), the rate-limiting enzyme coupling cytosolic glycolysis to mitochondrial citric acid cycle, plays a critical role in main...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.01.047

    authors: Xing G,Ren M,Watson WD,O'Neill JT,Verma A

    更新日期:2009-04-17 00:00:00

  • Frontal but not parietal positivity during source recollection is sensitive to episodic content.

    abstract::Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.03.019

    authors: Peters J,Daum I

    更新日期:2009-05-01 00:00:00