Short-term synaptic plasticity in the rat geniculo-cortical pathway during development in vivo.

abstract：:Cocaine's enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process. A large body of data indicates that opioids and dopamine together mediate emoti...

journal_title：Neuroscience letters

authors： Ambrose LM,Gallagher SM,Unterwald EM,Van Bockstaele EJ

更新日期：2006-05-22 00:00:00

abstract：:This study was aimed to evaluate effects of peptides from Phascolosoma esculenta and its ferrous-chelating peptides on spatial learning and memory in mice by Morris water maze test. 100mg/kg peptide on spatial learning and memory function about quadrant time and passing times through the platform better than 50 and 15...

journal_title：Neuroscience letters

authors： Liu L,Cao J,Chen J,Zhang X,Wu Z,Xiang H

更新日期：2016-09-19 00:00:00

abstract：:Seizures in genetically epilepsy-prone rats (GEPRs) may result from hypoactivity of locus coeruleus (LC) neurons during seizures. This study examined Fos-like-immunoreactivity (FLI) in the LC following audiogenic seizures in two strains of GEPRs (GEPR-9s and -3s), and following pentylenetetrazol (PTZ) or maximal elect...

journal_title：Neuroscience letters

authors： Eells JB,Clough RW,Browning RA,Jobe PC

更新日期：1997-09-12 00:00:00

abstract：:By means of light microscopic autoradiography, binding sites for the gamma-aminobutyric acid (GABA) analogues, 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol ([7-3H]THIP), [3H]isoguvacine and [3H]baclofen were found on many cultured cerebellar and spinal neurons of fetal and newborn rats. The number of neurons labelle...

journal_title：Neuroscience letters

authors： Hösli E,Krogsgaard-Larsen P,Hösli L

更新日期：1985-10-24 00:00:00

abstract：:Spinocerebellar ataxias (SCAs) are a group of clinically and genetically heterogeneous neurological diseases. The expansion of unstable microsatellite repeats has been identified as the underlying pathogenic cause of 10 subtypes of autosomal dominant SCAs. The aetiology of sporadic SCA is unknown. The aim of this stud...

journal_title：Neuroscience letters

authors： Majounie E,Wardle M,Muzaimi M,Cross WC,Robertson NP,Williams NM,Morris HR

更新日期：2007-12-11 00:00:00

abstract：:The effect of the N-methyl-D-aspartate (NMDA) receptor antagonist, 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP), on the ethanol-evoked release of brain ascorbate (AA) was investigated in freely moving rats using an in vivo voltammetry technique. Ethanol (1.0 g/kg, intraperitoneal injection, i.p.) increase...

journal_title：Neuroscience letters

authors： Wu C

更新日期：1993-07-09 00:00:00

abstract：:Dendritic branching of neurons may be quantitatively studied using applications of graph theory. Dendritic ramifications may be considered as 'forests' of planted, stemmed, binary 'trees' with simple mathematical properties. Two fundamental numbers, that of dendritic tips and that of dendritic stems, usually suffice t...

journal_title：Neuroscience letters

authors： Percheron G

更新日期：1979-10-01 00:00:00

abstract：:To determine the involvement of the medial prefrontal cortex (mPFC) in operant-type delayed alternation, microinjections of muscimol into the mPFC were used for temporal inactivation during behavioral tests in rats. The temporal mPFC inactivation showed effects related to both dorsal (decreased delay-dependent correct...

journal_title：Neuroscience letters

authors： Izaki Y,Maruki K,Hori K,Nomura M

更新日期：2001-11-27 00:00:00

abstract：:APPsw transgenic mice showing substantial features of brain Abeta amyloidosis such as senile plaques and behavioral abnormalities were examined by immunostaining to determine whether Abeta deposits could induce the subsequent disturbance of neurotransmitter systems including somatostatin, substance P and choline acety...

journal_title：Neuroscience letters

authors： Tomidokoro Y,Harigaya Y,Matsubara E,Ikeda M,Kawarabayashi T,Okamoto K,Shoji M

更新日期：2000-10-13 00:00:00

abstract：:Immunolocalization of 14-3-3 protein isoforms in relation to Pick bodies in Pick body disease (PBD) brains was investigated. Weakly granular immunoreactivity of 14-3-3 proteins was found in neurons in control subjects and in Pick body disease brains. In addition to this granular immunoreactivity, many Pick bodies were...

journal_title：Neuroscience letters

authors： Umahara T,Uchihara T,Tsuchiya K,Nakamura A,Ikeda K,Iwamoto T,Takasaki M

更新日期：2004-11-23 00:00:00

abstract：:The pathological basis for essential tremor (ET) is unknown. We used proton magnetic resonance spectroscopic imaging (1H MRSI) in 16 ET patients and 11 controls to measure levels of intracellular metabolites, including N-acetyl-L-aspartate (NAA) and total choline, relative to total creatine (tCR), in several brain reg...

journal_title：Neuroscience letters

authors： Louis ED,Shungu DC,Chan S,Mao X,Jurewicz EC,Watner D

更新日期：2002-11-15 00:00:00

abstract：:Slightly suprathreshold magnetic stimuli were delivered over the left scalp while a normal human subject attended a sensory signal which called for a motor response of right fingers in a reaction time paradigm. The cortico-motoneuronal systems of the two muscles producing finger extension disclosed a remarkable physio...

journal_title：Neuroscience letters

authors： Tomberg C

更新日期：1995-02-06 00:00:00

abstract：:Cerebral perfusion is important in older adults as it is linked to cognitive declines. Physical activity can improve blood flow in the body but little is known about the relationship between physical activity and cerebral perfusion in older adults. In particular, no study has investigated the relation between strength...

journal_title：Neuroscience letters

authors： Xu X,Jerskey BA,Cote DM,Walsh EG,Hassenstab JJ,Ladino ME,Clark US,Labbe DR,Gunstad JJ,Poppas A,Cohen RA,Hoge RD,Sweet LH

更新日期：2014-02-07 00:00:00

abstract：:Oxidative stress is considered important for the pathogenesis of Alzheimer disease (AD), which is characterized by the formation of senile plaques rich in amyloid beta-protein (Abeta). Abeta cytotoxicity has been found dependent on lysosomes, which are abundant in AD neurons and are shown to partially co-localize with...

journal_title：Neuroscience letters

authors： Zheng L,Roberg K,Jerhammar F,Marcusson J,Terman A

更新日期：2006-02-20 00:00:00

abstract：:Several studies have indicated that higher levels of childhood aerobic fitness is associated with superior cognitive function, and this association is disproportionately observed in tasks requiring greater top-down control. We designed the current study to clarify the relationship between childhood fitness and top-dow...

journal_title：Neuroscience letters

authors： Kamijo K,Takeda Y,Takai Y,Haramura M

更新日期：2016-10-06 00:00:00

abstract：:The CA1 region of the rat hippocampal slice generates spontaneous electrographic seizures (field bursts) when exposed to ACSF containing < or = 0.2 mM calcium. It has been proposed that, particularly during the early part of a field burst, synchronised activity in small independent aggregates of neurons results in low...

journal_title：Neuroscience letters

authors： Fox JE,Bikson M,Jefferys JG

更新日期：2007-01-10 00:00:00

abstract：:Cold defense mechanisms in mice are attenuated in the light phase during fasting, resulting in hypothermia. The present study examined whether specific neurons and areas in the SCN are related to the response. Mice were fasted over 47h or remained fed, during which they were placed at 20 or 27°C for 3h in the light or...

journal_title：Neuroscience letters

authors： Uchida Y,Tokizawa K,Nagashima K

更新日期：2014-09-05 00:00:00

abstract：:Oxytocin (OT) modulation of synaptic transmission between olfactory bulb neurones has been implicated in the induction of maternal behaviour, but the mechanism of action is unknown. We examined the action of OT on gamma-aminobutyric acid(A) (GABA(A)) receptor-mediated spontaneous inhibitory postsynaptic currents (sIPS...

journal_title：Neuroscience letters

authors： Osako Y,Otsuka T,Taniguchi M,Oka T,Kaba H

更新日期：2000-07-28 00:00:00

abstract：:To identify choline acetyltransferase (ChAT) transcript(s) in human foetal brain we used the reverse polymerase chain reaction including different couples of oligonucleotide primers. The analysis indicated the presence of a new choline acetyltransferase transcript containing at its 5' end an untranslated exon (E1A) of...

journal_title：Neuroscience letters

authors： Schmitt M,Garnier JM,Simoni P,Quirin-Stricker C

更新日期：1994-09-12 00:00:00

abstract：:English /l/ and /r/ sounds are not distinctive for Japanese speakers and they are loosely associated with corresponding graphemes. The purpose of this study was to investigate the brain activities in the memory process for the graphemes containing 'l' and 'r' in Japanese speakers. Two functional magnetic resonance ima...

journal_title：Neuroscience letters

authors： Sumiyoshi C,Matsuo K,Kato C,Ozawa F,Takehara Y,Isoda H,Isogai S,Sakahara H,Nakai T

更新日期：2003-01-09 00:00:00

abstract：:The angular distribution of mitotic spindle fibers has been studied in the telencephalic ventricular zone (VZ) of mouse embryos and has been found to be monophasic and invariant during the early cortical histogenesis both in the normal and in a reeler embryo. This observation suggests that the orientation of mitotic s...

journal_title：Neuroscience letters

authors： Landrieu P,Goffinet A

更新日期：1979-06-01 00:00:00

abstract：:The neuronal number and nucleolar volume of the magnocellular population of the basal nucleus of Meynert in 6 patients with progressive supranuclear palsy (PSP) - one associated with Alzheimer's disease - were compared with those of 5 controls. In the 5 typical PSP cases, an age-dependent neuronal loss was demonstrate...

journal_title：Neuroscience letters

authors： Tagliavini F,Pilleri G,Bouras C,Constantinidis J

更新日期：1984-01-27 00:00:00

abstract：:Abnormal alteration of brain function is a characteristic complication of hepatic encephalopathy in both acute and chronic liver failure. Previous studies suggest that the pathogenesis of hepatic encephalopathy involves chronic glial edema with subsequent alteration of glioneuronal communication, N-methyl-d-aspartate ...

journal_title：Neuroscience letters

authors： Ohara K,Aoyama M,Fujita M,Sobue K,Asai K

更新日期：2009-09-22 00:00:00

abstract：:Associations between PIN1 gene polymorphisms and Alzheimer's disease (AD) risk remain controversial, possibly because single studies often lack sufficient statistical power. In this study, we performed a meta-analysis to evaluate the association of two commonly studied PIN1 polymorphisms, -842G/C and -667T/C, with the...

journal_title：Neuroscience letters

authors： Cao L,Wang F,Ge H,Wu PC,Qu P,Chen GH,Gao ZL

更新日期：2013-02-22 00:00:00

abstract：:Emotions are at the core of human cognition and behavior. Traditionally, emotions have been classified dichotomously as being either positive or negative. However, recent behavioral research (An et al., 2017) suggests that emotions contain both positivity and negativity. The current work investigated neural correlates...

journal_title：Neuroscience letters

authors： An S,Han X,Wu B,Shi Z,Marks M,Wang S,Wu X,Han S

更新日期：2018-09-25 00:00:00

abstract：:Effects of sleep deprivation (SD) on one-trial recognition memory were investigated in rats using either a spontaneous novel-object or object-place recognition test. Rats were allowed to explore a field in which two identical objects were presented. After a delay period, they were placed again in the same field in whi...

journal_title：Neuroscience letters

authors： Ishikawa H,Yamada K,Pavlides C,Ichitani Y

更新日期：2014-09-19 00:00:00

abstract：:The effects of bath-applied phorbol esters, protein kinase C (PKC) activators, and sphingosine, a PKC inhibitor, on membrane currents evoked by serotonin were studied in Xenopus oocytes injected with rat brain mRNA. The oscillatory Cl- current in response to bath-applied 50 nM serotonin was significantly depressed by ...

journal_title：Neuroscience letters

authors： Matsumoto M,Barnard EA

更新日期：1994-02-14 00:00:00

abstract：:The mechanisms underlying alterations in brain functions in response to physical exercise are not fully understood. The present study examined the central effect of irisin, a 112 amino acid polypeptide hormone secreted from the skeletal muscle after exercise, on the locomotion in rats. Central administration of irisin...

journal_title：Neuroscience letters

authors： Zhang W,Chang L,Zhang C,Zhang R,Li Z,Chai B,Li J,Chen E,Mulholland M

更新日期：2015-05-19 00:00:00

abstract：:The electrophysiological mechanism underlying afterhyperpolarization induced by the activation of the nicotinic acetylcholine receptor (nAChR) in male rat major pelvic ganglion neurons (MPG) was investigated using a gramicidin-perforated patch clamp and microscopic fluorescence measurement system. Acetylcholine (ACh) ...

journal_title：Neuroscience letters

authors： Park KS,Cha SK,Kim MJ,Kim NH,Lee JW,Jeong SW,Kong ID

更新日期：2010-09-27 00:00:00

abstract：:Mirror neurons, which have now been found in the human and songbird as well as the macaque, respond to both the observation and the performance of the same action. It has been suggested that their matching response properties have evolved as an adaptation for action understanding; alternatively, these properties may a...

journal_title：Neuroscience letters

authors： Catmur C

更新日期：2013-04-12 00:00:00