Afterhyperpolarization induced by the activation of nicotinic acetylcholine receptors in pelvic ganglion neurons of male rats.

abstract：:The purpose of this study was to identify the subcortical neural pathways which mediate adrenocortical responses following cortical stimulation. The frontal cortex was stimulated in intact rats and in animals with medial or lateral septal or preoptic lesions or with large or small anterior hypothalamic deafferentation...

journal_title：Neuroscience letters

authors： Feldman S,Conforti N

更新日期：1987-01-02 00:00:00

abstract：:Bereitschaftspotentials (BPs) preceding muscle relaxation and contraction were compared by using subdural electrodes which were implanted onto the right medial frontal surface in two patients with supplementary motor area (SMA) seizure. The applied movement paradigm (muscle relaxation and contraction tasks) was comple...

journal_title：Neuroscience letters

authors： Yazawa S,Ikeda A,Kunieda T,Mima T,Nagamine T,Ohara S,Terada K,Taki W,Kimura J,Shibasaki H

更新日期：1998-03-20 00:00:00

abstract：:It is known that depolarization of cortical cells in vivo during cortical spreading depression (CSD) is accompanied by accumulation of cyclic AMP (cAMP). Under similar conditions in vitro adenosine release has been demonstrated. The present study investigates the possible role of adenosine in the mechanism of CSD. Top...

journal_title：Neuroscience letters

authors： Ueda M,Krivánek J

更新日期：1977-03-01 00:00:00

abstract：:Acetylcholinesterase (AChE) is an essential enzymatic component of the neuromuscular junction where it is responsible for terminating neurotransmission by the cholinergic motor neurons. The enzyme at the neuromuscular junction (NMJ) is contributed primarily by the skeletal muscle where it is produced at higher levels ...

journal_title：Neuroscience letters

authors： Rotundo RL

更新日期：2020-09-14 00:00:00

abstract：:The learned helplessness (LH) developed after repeat inescapable stress is a well validated animal model of human major depression and is not species specific. c-Fos, the protein product of the protooncogene c-fos, is expressed in neurons under a variety of stressors and could reflect the regional neuronal activation....

journal_title：Neuroscience letters

authors： Huang YH,Cheng CY,Hong CJ,Tsai SJ

更新日期：2004-06-17 00:00:00

abstract：:Using renal arteries from young (6 months), mature (18 months) and old (70 months) rabbits, the effect of dopamine on 3',5'-cyclic adenosine monophosphate (cAMP) generation was studied. No significant differences in basal adenylate cyclase values were found in homogenates of renal artery from young, mature or old rabb...

journal_title：Neuroscience letters

authors： Amenta F,Cavallotti C,Collier WL,Iacopino L

更新日期：1984-10-26 00:00:00

abstract：:Frequent and persistent stressful events caused depressive illness. Stress is an aversive stimulus which disturbs physiological homeostasis and reflects a variety of biological systems. The present study was designed to investigate the nitric oxide mechanism in the protective effect of imipramine and venlafaxine again...

journal_title：Neuroscience letters

authors： Kumar A,Garg R,Gaur V,Kumar P

更新日期：2009-12-25 00:00:00

abstract：:Limited work has been done to investigate the molecular mechanisms behind the process of demyelination and remyelination that occurs in response to chronic nerve compression (CNC) injury. In the present study, we investigated the expression of the transcription factors krox-20 and c-jun, positive and negative regulato...

journal_title：Neuroscience letters

authors： Pham K,Nassiri N,Gupta R

更新日期：2009-11-13 00:00:00

abstract：:Electrical high frequency deep brain stimulation (DBS) of the globus pallidus internus (GPi) or the subthalamic nucleus (STN) has dramatic beneficial motor effects in advanced Parkinson's disease (PD). However, the mechanisms underlying these clinical results remain unclear. It is proposed that the gamma-aminobutyric ...

journal_title：Neuroscience letters

authors： Li T,Qadri F,Moser A

更新日期：2004-11-23 00:00:00

abstract：:The cellular prion protein (PrP(C)) is crucial for the development of transmissible spongiform encephalopathies (TSEs), where the pathogenic scrapie isoform (PrP(Sc)) of the same protein, is considered to be the principal or sole infectious agent. Here, we report findings on PrP(C) expression in the rat forebrain, usi...

journal_title：Neuroscience letters

authors： Verghese-Nikolakaki S,Michaloudi H,Polymenidou M,Groschup MH,Papadopoulos GC,Sklaviadis T

更新日期：1999-09-03 00:00:00

abstract：:Recently, we have reported that erythropoietin (Epo) provides neuroprotection in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-induced neurotoxicity in vivo. In the present study, we investigated the effects of single Epo administration on brain antioxidant enzyme (superoxide dismutase (SOD) and glutathion perox...

journal_title：Neuroscience letters

authors： Genc S,Akhisaroglu M,Kuralay F,Genc K

更新日期：2002-03-15 00:00:00

abstract：:Rapid removal of synaptically released glutamate from the extracellular space ensures a high signal-to-noise ratio in excitatory neurotransmission. In the cerebellum, glial glutamate transporters, GLAST and GLT-1, are co-localized in the processes of Bergmann glia wrapping excitatory synapses on Purkinje cells (PCs). ...

journal_title：Neuroscience letters

authors： Takatsuru Y,Iino M,Tanaka K,Ozawa S

更新日期：2007-06-08 00:00:00

abstract：:The adenosine triphosphate (ATP)-dependent sodium/potassium pump extrudes intracellular sodium in exchange for extracellular potassium. Low ATP causes pump dysfunction increasing both intracellular sodium and water thereby enhancing metabolite mobility. This should be detectable by proton magnetic resonance spectrosco...

journal_title：Neuroscience letters

authors： Cady EB,Lorek A,Penrice J,Wylezinska M,Cooper CE,Brown GC,Owen-Reece H,Kirkbride V,Wyatt JS,Osmund E

更新日期：1994-12-05 00:00:00

abstract：:Peripheral inflammation induced by intraperitoneal (i.p.) injection of Lipopolysaccharide (LPS) is known to cause functional impairments in the brain affecting memory and learning. One of mechanisms may be the interference with neurotrophin (NT) expression and function. In the current study we administered a single, h...

journal_title：Neuroscience letters

authors： Schnydrig S,Korner L,Landweer S,Ernst B,Walker G,Otten U,Kunz D

更新日期：2007-12-11 00:00:00

abstract：:The effects of morphine (0.2-200 micrograms/kg) administered into the brain stem via a vertebral artery on the somatosympathetic A- and C-reflexes evoked in a cardiac sympathetic nerve by electrical stimulation of somatic myelinated (A) and unmyelinated (C) afferent nerve fibers in anesthetized cats were examined. The...

journal_title：Neuroscience letters

authors： Kato J,Meguro K,Sato A,Sato Y

更新日期：1992-04-27 00:00:00

abstract：:Learning is important for humans and can be disrupted by disease. However, the essence of how learning may be represented within a neuronal network is still elusive. Spike trains generated by neurons have been demonstrated to carry information which is relevant for learning. The present study uses well-established mut...

journal_title：Neuroscience letters

authors： Jog MS,Aur D,Connolly CI

更新日期：2007-01-22 00:00:00

abstract：:Our previous genetic and proteomic studies demonstrated that dynamin 1 is significantly associated with nicotine dependence (ND) in human smokers and its expression is highly modulated by nicotine in the brains of animals. To provide further molecular evidence for the involvement of dynamin 1 in the etiology of ND, we...

journal_title：Neuroscience letters

authors： Xu Q,Li MD

更新日期：2011-02-11 00:00:00

abstract：:Using the monoclonal antibody, ME 20.4, against the p75 nerve growth factor (NGF) receptor, NGF receptor-like immunoreactivity has been identified in axonal processes innervating the human hippocampus, where previously a loss of reactivity has been reported in a preliminary study of Alzheimer's disease [10]. In an ext...

journal_title：Neuroscience letters

authors： Kerwin JM,Morris CM,Perry RH,Perry EK

更新日期：1992-08-31 00:00:00

abstract：:It is known that the number of newly generated neurons is increased in the young and adult rodent subventricular zone (SVZ) and dentate gyrus (DG) after transient brain ischemia. However, it remains unclear whether increase in neurogenesis in the adult DG induced by ischemic stroke is transient or sustained. We here r...

journal_title：Neuroscience letters

authors： Wang C,Zhang M,Sun C,Cai Y,You Y,Huang L,Liu F

更新日期：2011-01-13 00:00:00

abstract：:Alzheimer disease (AD) is the most common type of dementia, and is currently incurable. The efficacy of existing treatments for AD such as acetylcholinesterase inhibitors is limited to symptom improvement. Research on disease-modifying therapies (DMTs) has conventionally focused on amelioration of CNS pathogenesis. Tw...

journal_title：Neuroscience letters

authors： Shozawa H,Oguchi T,Tsuji M,Yano S,Kiuchi Y,Ono K

更新日期：2018-06-11 00:00:00

abstract：:Projection of the vagal C-afferent to the insular cortex was examined in rats. Electrical activation of the C-afferent resulted in two cortical field potentials in the anterior insula. They were independent of each other and neither of them was attributed to the specific thalamic projection. These results imply that v...

journal_title：Neuroscience letters

authors： Ito S

更新日期：1992-12-14 00:00:00

abstract：:Patch-clamp pipettes filled with 50-5000 microM glutamate were placed on crayfish muscle fibers treated with collagenase, formed G omega seals and elicited single-channel currents with a main amplitude of about -8 pA at -70 mV membrane potential, representing a conductance of about 100 pS (19 degrees C). Evaluation of...

journal_title：Neuroscience letters

authors： Franke C,Dudel J

更新日期：1985-09-06 00:00:00

abstract：:Wild-type neuronal calcium-binding protein VILIP (visinin-like protein), and a myristoylation mutant of VILIP which lacks the consensus sequence for N-terminal myristoylation, have been stably transfected in PC12 cells. Immunocytochemical studies of VILIP-transfected PC12 cells have revealed the wild-type VILIP is str...

journal_title：Neuroscience letters

authors： Spilker C,Gundelfinger ED,Braunewell KH

更新日期：1997-04-04 00:00:00

abstract：:Mental activity which engages one half of the brain is usually accompanied by a suppression of alpha rhythm that is greater over the active hemisphere. When the left hemisphere is active, as during mental arithmetic, the magnitude of the asymmetry in the alpha rhythm is proportional to the rate at which subjects perfo...

journal_title：Neuroscience letters

authors： Glass A,Butler SR

更新日期：1977-03-01 00:00:00

abstract：:With the use of the microdialysis technique, we examined the modulatory effect of ketamine on catecholamine efflux from in vivo cardiac sympathetic nerve endings. A dialysis probe was implanted in the left ventricular myocardium, and dialysate norepinephrine (NE) levels in anesthetized cats were measured with liquid c...

journal_title：Neuroscience letters

authors： Kitagawa H,Yamazaki T,Akiyama T,Yahagi N,Kawada T,Mori H,Sunagawa K

更新日期：2002-05-24 00:00:00

abstract：:The morphology of single saccular afferents was studied by the intracellular horseradish peroxidase (HRP) method. Four neurons were sufficiently stained to allow reconstruction of their axonal arborizations. The main axon of these neurons bifurcated into an ascending and a descending branch at the level of the lateral...

journal_title：Neuroscience letters

authors： Imagawa M,Graf W,Sato H,Suwa H,Isu N,Izumi R,Uchino Y

更新日期：1998-01-16 00:00:00

abstract：:Olprinone, an inhibitor of cyclic nucleotide phosphodiesterase III, inhibited an increase in intracellular Ca(2+) concentrations for acutely dissociated rat hippocampal pyramidal neurons induced by extracellular high K(+) (35 mM) depolarization. Olprinone (100 microM) significantly reduced spontaneous glutamate releas...

journal_title：Neuroscience letters

authors： Fujikawa H,Kanno T,Nagata T,Nishizaki T

更新日期：2008-12-26 00:00:00

abstract：:Morphine analgesia measured by the tail withdrawal test was examined in rats that were either restrained or left free during testing. It was found that restraint potentiated morphine analgesia and decreased the latency of the peak analgesic effect. Methysergide, a serotonin antagonist, and valine, which prevents the i...

journal_title：Neuroscience letters

authors： Kelly SJ,Franklin KB

更新日期：1984-02-24 00:00:00

abstract：:Repeated stress triggers a wide range of adaptive changes in the central nervous system including the elevation of serotonin (5-HT) metabolism and an increased susceptibility to affective disorders. To begin to examine whether these changes are mediated by alterations in gene expression for tryptophan hydroxylase (TPH...

journal_title：Neuroscience letters

authors： Chamas F,Serova L,Sabban EL

更新日期：1999-06-04 00:00:00

abstract：:gamma-Aminobutyric acidA (GABA(A)) gated chloride ion channels were expressed from human recombinant cDNA using the baculovirus/Sf-9 insect cell expression system. The electrophysiological effects in whole-cell currents of 5-(4-piperidyl) isoxazol-3-ol (4-PIOL), a GABA(A) receptor partial agonist, were investigated on...

journal_title：Neuroscience letters

authors： Westh-Hansen SE,Noguchi K,Witt MR,Murai Y,Nielsen M,Akaike N

更新日期：1997-07-11 00:00:00