Effect of transposition on contractile and histochemical properties of muscle.

Abstract:

:In 16 rats, the extensor digitorum longus (EDL) - a fast muscle - was grafted, complete with its innervation, into the bed of the (removed) soleus - a slow muscle. Following the transposition, performed on one side only, EDL recovered and showed the contraction time of the contralateral EDL that served as control. However, as demonstrated histochemically, the transposed EDL exhibited a different succinic dehydrogenase activity: it acquired the muscle fiber pattern of the slow red soleus muscle. This method of transposition of muscle plus nerve allows the study of nerve-muscle relationships with respect to a multiple regulation of muscle properties, including the decisive role of neuronal specificity and other mechanisms such as substrate (oxygen) supply.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Gutmann E

doi

10.1016/0304-3940(76)90159-2

subject

Has Abstract

pub_date

1976-07-01 00:00:00

pages

273-7

issue

5

eissn

0304-3940

issn

1872-7972

pii

0304-3940(76)90159-2

journal_volume

2

pub_type

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