Abstract:
:In 16 rats, the extensor digitorum longus (EDL) - a fast muscle - was grafted, complete with its innervation, into the bed of the (removed) soleus - a slow muscle. Following the transposition, performed on one side only, EDL recovered and showed the contraction time of the contralateral EDL that served as control. However, as demonstrated histochemically, the transposed EDL exhibited a different succinic dehydrogenase activity: it acquired the muscle fiber pattern of the slow red soleus muscle. This method of transposition of muscle plus nerve allows the study of nerve-muscle relationships with respect to a multiple regulation of muscle properties, including the decisive role of neuronal specificity and other mechanisms such as substrate (oxygen) supply.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Gutmann Edoi
10.1016/0304-3940(76)90159-2subject
Has Abstractpub_date
1976-07-01 00:00:00pages
273-7issue
5eissn
0304-3940issn
1872-7972pii
0304-3940(76)90159-2journal_volume
2pub_type
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