Abstract:
:To evaluate possible prespike field synchronizations, its relation to both interictal discharges and postspike return to baseline, penicillin-induced cortical interictal discharges were recorded in anaesthetized rabbits by magnetoencephalography (MEG) and electrocorticography (EcoG). Statistical parameters of spatial (global field power (GFP)) and temporal properties (Z-parameter) of field synchronization were calculated. In our previous report, three types of prespike field synchronization were found before the onset of interictal spike. We report here that the continuous and fluctuating, but not the abrupt prespike increases, were more often associated with a spike and wave pattern of interictal discharge than with a spike alone. Furthermore, the postspike return of these statistical parameters shows the same three patterns as the prespike field synchronizations, but in the inverse time sequence. More often than not pre- and postspike pattern were of the same type. The results suggest an influence of prespike field synchronization upon interictal discharge and subsequent field return dynamics.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Zwiener U,Eiselt M,Giessler F,Nowak Hdoi
10.1016/s0304-3940(00)01271-4keywords:
subject
Has Abstractpub_date
2000-08-04 00:00:00pages
103-6issue
2eissn
0304-3940issn
1872-7972pii
S0304-3940(00)01271-4journal_volume
289pub_type
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