Ultrastructural studies of medullary synaptic inputs to vasopressin-immunoreactive neurons in the supraoptic nucleus of the rat hypothalamus.

Abstract:

:Direct projections from the A1/C1 catecholaminergic cell group in the caudal ventrolateral medulla oblongata to neurons containing vasopressin (VP) in the supraoptic nucleus (SON) were studied electron microscopically by a double-labeling technique which combines anterograde tracing after injection of wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) into the A1/C1 cell group with VP immunocytochemistry. WGA-HRP-labeled axon terminals originating from neurons in the A1/C1 cell group were found to make synaptic contacts with VP-immunoreactive cell bodies and dendrites in the SON, most often forming axo-dendritic synapses. This indicates that VP-containing neurosecretory neurons in the SON receive monosynaptic catecholaminergic input from the A1/C1 cell group.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Shioda S,Shimoda Y,Nakai Y

doi

10.1016/0304-3940(92)90828-u

keywords:

subject

Has Abstract

pub_date

1992-12-14 00:00:00

pages

155-8

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(92)90828-U

journal_volume

148

pub_type

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