Differential regulation of SC1/PRDM4 and PRMT5 mediated protein arginine methylation by the nerve growth factor and the epidermal growth factor in PC12 cells.

abstract：:To investigate the effects of bromazepam on motor performance and electroencephalographic activity (qEEG) in healthy subjects, during the process of learning a typewriting task, with a focused attention demand. A randomized double-blind model was used to allocate subjects in one of the following conditions: placebo (n...

journal_title：Neuroscience letters

authors： Cunha M,Machado D,Bastos VH,Ferreira C,Cagy M,Basile L,Piedade R,Ribeiro P

更新日期：2006-10-23 00:00:00

abstract：:Much research is focused on developing novel drugs to improve memory. In particular, psychostimulants have been shown to enhance memory and have a long history of safe use in humans. In prior work, we have shown that very low doses of amphetamine administered before training on a Pavlovian fear-conditioning task can d...

journal_title：Neuroscience letters

authors： Carmack SA,Wood SC,Anagnostaras SG

更新日期：2010-01-01 00:00:00

abstract：:LHRH administration is reported to facilitate male sexual behavior. The aim of the present study was to investigate whether male sexual behavior is associated with the number of LHRH neurons in the forebrain in middle-aged rats. Male Long-Evans rats (18-19 months) were assigned to three groups on the basis of sexual p...

journal_title：Neuroscience letters

authors： Tsai YF,Tsai HW,Tai MY,Huang RL,Peng MT

更新日期：1997-11-21 00:00:00

abstract：:Hippocampal synaptic plasticity between Schaffer collaterals and CA1 pyramidal neurons can be induced by activation of N-methyl-d-aspartate receptors (NMDARs) or of metabotropic glutamate receptors (mGluRs). Inhibitory GABAergic interneurons in this region abundantly terminate on pyramidal neurons and may thus influen...

journal_title：Neuroscience letters

authors： Rohde M,Tokay T,Köhling R,Kirschstein T

更新日期：2009-12-18 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic inflammatory CNS disorder, resulting in progressive neurological dysfunction. The disease has a higher incidence in Caucasian Americans (CA) than African Americans (AA); however, the latter may have a more aggressive disease course. We used cluster analysis to determine whether the...

journal_title：Neuroscience letters

authors： Huang R,Hughes M,Mobley S,Lanham I,Poduslo SE

更新日期：2007-02-27 00:00:00

abstract：:We have conjectured that axons embody a post transcriptional sprouting programme repressed by mature Schwann cells. Injured nerves of Wld(s) mice neither degenerate nor regenerate for several weeks but axons do regrow if the resident cells of the distal stump are destroyed. To test our hypothesis we made an extended c...

journal_title：Neuroscience letters

authors： Iñiguez A,Alvarez J

更新日期：1999-06-18 00:00:00

abstract：:A two-stage model of sustained neural activity in the prefrontal cortex is proposed in order to simulate feature binding and capacity limits in visual working memory. In the first stage, object features are stored in parallel network layers without explicit conjunctions. A second stage binds features into integrated o...

journal_title：Neuroscience letters

authors： Domijan D

更新日期：2003-10-23 00:00:00

abstract：:The opioid peptide dynorphin decreased somatic calcium-dependent action potential duration in a portion of mouse dorsal root ganglion (DRG) neurons without altering resting membrane potential or conductance. Dynorphin action was antagonized by naloxone. Responses of DRG neurons to dynorphin differed from responses to ...

journal_title：Neuroscience letters

authors： Werz MA,Macdonald RL

更新日期：1984-05-04 00:00:00

abstract：:Accumulating evidence indicates that somatostatin (SS) is a key substance for the circadian rhythm of rodents. In the present study, we investigated whether SS mRNA coexists with arginine-vasopressin (AVP) mRNA, vasoactive intestinal peptide/peptide histidine isoleucine amide (VIP/PHI) mRNA and glutamate decarboxylase...

journal_title：Neuroscience letters

authors： Tanaka M,Okamura H,Matsuda T,Shigeyoshi Y,Hisa Y,Chihara K,Ibata Y

更新日期：1996-09-06 00:00:00

abstract：:The present study was performed to explore the role of galanin in nociceptive modulation in anterior cingulate cortex (ACC) of rats with acute inflammation, and the changes in galanin and galanin receptor 2 (Gal R2) expressions in rats with acute inflammation. Intra-ACC injection of galanin induced antinociception in ...

journal_title：Neuroscience letters

authors： Zhang ML,Fu FH,Yu LC

更新日期：2017-01-18 00:00:00

abstract：:Crude membrane preparations from the dorsomedial medulla and whole heart of adult rats were used to characterize muscarinic receptors (mChRs) in the nucleus tractus solitarius (NTS). Isotherm binding assays with [3H]quinuclidinyl benzilate ([3H]QNB) indicated a uniform population of muscarinic cholinergic receptors in...

journal_title：Neuroscience letters

authors： Goodwin BP,Anderson GF,Barraco RA

更新日期：1995-05-19 00:00:00

abstract：:The effect of insulin-induced hypoglycemic stress on the concentrations of immunoreactive beta-endorphin (ir beta-EP) in plasma and cerebrospinal fluid (CSF) was examined in conscious non-pregnant ewes in which the cisterna magna and a jugular vein had been previously catheterized. In control experiments, no significa...

journal_title：Neuroscience letters

authors： Owens PC,Smith R,Green D,Falconer L

更新日期：1984-08-24 00:00:00

abstract：:The insular cortex (IC) contributes to nociceptive information processing. IC neurons express opioid receptors, including the mu (MOR), kappa (KOR), and delta (DOR) subtypes. Opioidergic agonists suppress excitatory synaptic transmission in the cerebral cortex. In addition, morphine injection into the IC reduces respo...

journal_title：Neuroscience letters

authors： Yokota E,Koyanagi Y,Nakamura H,Horinuki E,Oi Y,Kobayashi M

更新日期：2016-08-15 00:00:00

abstract：:The present study was designed to determine whether the p53 tumor-suppressor protein is involved in the development of antinociceptive tolerance to morphine. When the doses of morphine (mg/kg per injection) were subcutaneously given into mice as pretreatment twice daily for 2 days (first day (30) and second day (60)),...

journal_title：Neuroscience letters

authors： Tan-No K,Shimoda M,Watanabe K,Nakagawasai O,Niijima F,Kanno S,Ishikawa M,Bakalkin G,Tadano T

更新日期：2009-02-06 00:00:00

abstract：:The CA1 region of the rat hippocampal slice generates spontaneous electrographic seizures (field bursts) when exposed to ACSF containing < or = 0.2 mM calcium. It has been proposed that, particularly during the early part of a field burst, synchronised activity in small independent aggregates of neurons results in low...

journal_title：Neuroscience letters

authors： Fox JE,Bikson M,Jefferys JG

更新日期：2007-01-10 00:00:00

abstract：:The potassium conductance (gK) blockers tetraethylammonium (TEA) and 4-aminopyridine (4-AP) strongly excited experimental neuromas that had spontaneous discharge, but had minimal effects on acutely cut nerves and on old, quiescent neuromas. Resting gK apparently moderates hyperexcitability in active neuromas. ...

journal_title：Neuroscience letters

authors： Devor M

更新日期：1983-09-30 00:00:00

abstract：:In order to clarify the mechanism of action of cerulenin analog, C75, known to suppress feeding behavior, food intake was measured in adult CD-1 male mice n=5 per group, treated i.p. with 10 and 20mg/kg of C75. Animals in both treatment groups had significantly lower 24h food consumption rate relative to the control g...

journal_title：Neuroscience letters

authors： Binienda ZK,Ross IA,Gough B,Riccio T,Kim CS,Ali SF

更新日期：2010-01-29 00:00:00

abstract：:Although the relationship between hyperglycemia (using diabetic animal model) and plasma nitrotyrosine level has been studied, the effect of hypoglycemia on nitrotyrosine level in the brain has not been addressed. Here, we evaluated nitration of protein, the colocalization of nitration with alpha-synuclein, activity o...

journal_title：Neuroscience letters

authors： Liu Y,He R

更新日期：2010-03-26 00:00:00

abstract：:Fluorescent tracers (Nuclear Yellow, True Blue, Fast Blue) were injected, in various combinations, into the globus pallidus and substantia nigra in three marmosets. Examination of perikarya in the ipsilateral neostriatum, well removed from pallidal injection sites, revealed that the predominant pattern was of single-l...

journal_title：Neuroscience letters

authors： Féger J,Crossman AR

更新日期：1984-08-24 00:00:00

abstract：:Most single fibers of the cochlear nerve (CN) in 22 cats exhibited effects of mechanical interaction in one cochlea between two sounds applied binaurally, similarly to results in two cats in which the contralateral CN was transected. In 11 of 189 fibers, the spontaneous and/or the sound-evoked activity was suppressed ...

journal_title：Neuroscience letters

authors： Murata K,Tanahashi T,Horikawa J,Funai H

更新日期：1980-07-01 00:00:00

abstract：:Event-related potentials were recorded from sleeping newborns to compare amplitudes and latencies of mismatch negativity (MMN) and late discriminative negativity (LDN) in active and quiet sleep stages. MMN and LDN were obtained in response to changes in semi-synthesized vowels from 20 healthy newborn infants. MMN and ...

journal_title：Neuroscience letters

authors： Martynova O,Kirjavainen J,Cheour M

更新日期：2003-04-10 00:00:00

abstract：:Alzheimer's disease (AD) is a complex disease with the possible involvement of several genes. Genetic studies on sporadic late-onset AD have determined APOE*4 to be the major risk factor. Members of the synuclein gene family are potential candidates for the risk of AD. The persyn gene (gamma-synuclein) has recently be...

journal_title：Neuroscience letters

authors： Luedecking EK,Ganguli M,DeKosky ST,Kamboh MI

更新日期：1999-02-19 00:00:00

abstract：:Cocaine-induced modifications of glutamatergic synaptic transmission in the mesolimbic system play a key role in adaptations that promote addictive behaviors. In particular, the activation of ionotropic glutamate N-methyl-D-aspartate receptor (NMDAR) in the ventral tegmental area (VTA) is critical for both cocaine-ind...

journal_title：Neuroscience letters

authors： Schumann J,Matzner H,Michaeli A,Yaka R

更新日期：2009-09-18 00:00:00

abstract：:beta-Amyloid protein immunoreactivity in neocortex and hippocampus of Alzheimer's disease and control brains has been measured using an automatic image analysis system. Successive fields from the pial surface to white matter in 4 neocortical sites, parahippocampal gyrus and along the pyramidal cell layer in the hippoc...

journal_title：Neuroscience letters

authors： Cairns NJ,Chadwick A,Luthert PJ,Lantos PL

更新日期：1991-08-05 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) plays an important role in the regulation of energy balance. While the regulation of TRH in the paraventricular nucleus (PVN) in response to changes of energy balance has been well studied, how TRH is regulated in the dorsomedial hypothalamus (DMH) in maintaining energy homeostasis ...

journal_title：Neuroscience letters

authors： Zhang N,Zhang HY,Bi SA,Moran TH,Bi S

更新日期：2019-06-11 00:00:00

abstract：:Adult monkeys who have been under training over a long period of time show a loss of the M2 component in their biceps electromyographic response to brief, random perturbations of an alternating arm movement, the M1 component being apparently enhanced. These changes of the stretch-induced responses indicate a long-term...

journal_title：Neuroscience letters

authors： Christakos CN,Wolf H,Meyer-Lohmann J

更新日期：1983-11-11 00:00:00

abstract：:This study assessed the effect of the kappa opioid receptor agonist U50,488 administered into the rat temporomandibular joint (TMJ) on nociceptive behavioral responses evoked by formalin injected into the same site. Groups consisted of females, stratified into proestrus and diestrus phases of the estrous cycle, and ma...

journal_title：Neuroscience letters

authors： Clemente JT,Parada CA,Veiga MC,Gear RW,Tambeli CH

更新日期：2004-12-06 00:00:00

abstract：:Different responses evoked by stimulation of contralateral hippocampus at various levels are examined in new-born rabbits up to 1 month of age. Commissural fibres coming from the CA3-CA4 reach the contralateral regio superior (CA1) essentially at the st. oriens levels. CA1 responses elicited by stimulation of the cont...

journal_title：Neuroscience letters

authors： Thomson MA

更新日期：1979-02-01 00:00:00

abstract：:The effects of stress on carcinogenesis have been equivocal. The present work examined the influence of an unpredictable pattern of chronic restraint stress on estradiol-induced pituitary hyperplasia in male Fischer 344 rats. The animals were grouped as follows: (1) control, (2) stressed, (3) estradiol (31 mg), subcut...

journal_title：Neuroscience letters

authors： Gottesfeld Z,Liehr JG

更新日期：1987-09-11 00:00:00

abstract：:Cyclin-dependent kinase 5 (cdk5) is a homologue of cell division cycle 2 (cdc2)-like protein kinase. It is mainly expressed in neurons, and supposed to be involved in the dynamic change of neurocytoskeleton structure seen in the brain after ischemia. In the present study, we investigated immunoreactivity for cdk5 and ...

journal_title：Neuroscience letters

authors： Hayashi T,Warita H,Abe K,Itoyama Y

更新日期：1999-04-09 00:00:00