Genetic polymorphism in the persyn (gamma-synuclein) gene and the risk of Alzheimer's disease.

abstract：:In the present study we aimed at evaluating the prevalence and the associated clinical, neuropsychological and behavioral features of extrapyramidal symptoms in Frontotemporal Dementia (FTD) patients. Seventy-five patients fulfilling clinical criteria of FTD were consecutively enrolled. Each patient underwent clinical...

journal_title：Neuroscience letters

authors： Padovani A,Agosti C,Premi E,Bellelli G,Borroni B

更新日期：2007-07-05 00:00:00

abstract：:Disturbed motor control of the fingers, as revealed by the response to unexpected loading of an object held in a precision grip, or to finger perturbation during isometric holding, has been studied in patients with Huntington's disease (HD) and in normal subjects. In normal subjects unexpected loading elicited a refle...

journal_title：Neuroscience letters

authors： Fellows S,Schwarz M,Schaffrath C,Dömges F,Noth J

更新日期：1997-04-25 00:00:00

abstract：:Peripheral nerve damage causes a dramatic alteration to the gene expression in primary sensory neurons, changes within the neuronal cell body giving rise to an altered phenotype, adapted for axonal regeneration. Such changes suggest an alteration in activity, or levels, of cellular transcription factors. The POU famil...

journal_title：Neuroscience letters

authors： Begbie JL,Wood JN,Anderson PN,Latchman DS

更新日期：1996-04-05 00:00:00

abstract：:The perception of global coherent motion perception in complex motion patterns containing different direction vectors was investigated. Random dot kinematograms (RDK), plaids and fragmented plaid pattern were presented in which direction vectors of the moving elements were varied. In order to elicit coherent motion pe...

journal_title：Neuroscience letters

authors： Niedeggen M,Wist ER

更新日期：1998-04-24 00:00:00

abstract：:Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60-70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce oxidative stress, and prevent diabetes and non-alcoholic fatty liver disease. However, it is unclear whether Spirulina maxima 70% ethanol extra...

journal_title：Neuroscience letters

authors： Koh EJ,Kim KJ,Choi J,Kang DH,Lee BY

更新日期：2018-04-23 00:00:00

abstract：:An ionotropic glutamate receptor of the kainate subtype (GluR6) and a G-protein coupled metabotropic glutamate receptor (mGluR1 alpha) were expressed and studied in two insect cell lines: sf9 cells from Spodoptera frugiperda and MG1 cells from Trichoplusia ni. Application of kainate to GluR6-infected MG1 cells produce...

journal_title：Neuroscience letters

authors： Ross SM,Taverna FA,Pickering DS,Wang LY,MacDonald JF,Pennefather PS,Hampson DR

更新日期：1994-05-23 00:00:00

abstract：:The aim of this study was to investigate trigeminal nerve involvement in patients with peripheral facial palsy. In total, 25 patients with facial nerve palsy and 19 controls were tested by electrophysiological methods regarding their facial and trigeminal nerve functions within 1 month after disease onset. The presenc...

journal_title：Neuroscience letters

authors： Uluduz D,Kiziltan ME,Akalin MA

更新日期：2010-07-26 00:00:00

abstract：:In anorexia nervosa patients, body image distortion is a core and often persistent symptom, which continues to pose a risk for relapse even after weight recovery. Using functional magnetic resonance imaging (fMRI) in combination with a computer-based life image distortion technique, we stimulated female anorectic pati...

journal_title：Neuroscience letters

authors： Seeger G,Braus DF,Ruf M,Goldberger U,Schmidt MH

更新日期：2002-06-21 00:00:00

abstract：:In an attempt to understand the changes of circulating neuropeptide Y (NPY) during hypoxia, the plasma level of NPY was investigated by radioimmunoassay. Exposure of rats to hypobaric hypoxia at an altitude of 18,000 ft for 4 weeks causes an increase of pulmonary pressure and an elevation of plasma NPY-like immunoreac...

journal_title：Neuroscience letters

authors： Cheng JT,Chen CF,Shum AY,Wang JY,Chen HI

更新日期：1992-06-22 00:00:00

abstract：:By observing the ultrastructural intracellular Ca2+ distribution with Ca(2+)-oxalate-pyroantimonate method, we examined whether the protective mechanism of the nitric oxide (NO) synthase inhibitor, N omega-nitro-L-arginine (LNNA), involves change of the intracellular Ca2+ movement in delayed neuronal death (DND) in ge...

journal_title：Neuroscience letters

authors： Kohno K,Higuchi T,Ohta S,Kohno K,Kumon Y,Sakaki S

更新日期：1997-03-07 00:00:00

abstract：:The expression of neuronal nicotinic acetylcholine receptors (nAChRs) influenced by lipid peroxidation has been investigated. The results showed that exposure of PC12 cells to a free radical insult (FeSO(4)) induced concentration-dependent increase in level of MDA (malondialdehyde), and a significant decline in MTT [3...

journal_title：Neuroscience letters

authors： Guan Z,Zhang X,Nordberg A

更新日期：2000-06-09 00:00:00

abstract：:A study was carried out to determine at what stage of development the adult pattern of primary afferent projections to the substantia gelatinosa (SG) is first established. Horseradish peroxidase conjugated wheat-germ agglutinin (WGA-HRP) was applied to cut ends of sciatic nerves at mid-thigh level in adult and neonata...

journal_title：Neuroscience letters

authors： Fitzgerald M,Swett J

更新日期：1983-12-30 00:00:00

abstract：:The effect of pineal indoles on fast axoplasmic transport of proteins in the sciatic nerve was examined in rats injected with [3H]leucine in the sixth lumbar dorsal root ganglion. Melatonin (350-1100 nmol) applied locally in the sciatic nerve impaired significantly axonal transport. At a 350-nmol dose all other indole...

journal_title：Neuroscience letters

authors： Prevedello MR,Ritta MN,Cardinali DP

更新日期：1979-06-01 00:00:00

abstract：:Our previous study has shown that both electroacupuncture (EA) and vagus nerve stimulation (VNS) can inhibit cortical epileptiform activities induced by pentylenetetrazole (PTZ). The current study compared the effects of EA and VNS on thalamic neuronal responses to PTZ-induced epileptiform activities. Under general an...

journal_title：Neuroscience letters

authors： Zhang JL,Zhang SP,Zhang HQ

更新日期：2008-08-22 00:00:00

abstract：:The high-affinity, sodium-dependent uptake of dopamine (DA) was inhibited by the pretreatment of synaptosomes with neuraminidase from Vibrio cholerae. The inhibition was of a non-competitive type, resulting in a 40% decrease of Vmax. Neither basal nor depolarization-stimulated release of DA was affected. Treatment of ...

journal_title：Neuroscience letters

authors： Zaleska MM,Erecińska M

更新日期：1987-11-10 00:00:00

abstract：:In order to clarify the mechanism of action of cerulenin analog, C75, known to suppress feeding behavior, food intake was measured in adult CD-1 male mice n=5 per group, treated i.p. with 10 and 20mg/kg of C75. Animals in both treatment groups had significantly lower 24h food consumption rate relative to the control g...

journal_title：Neuroscience letters

authors： Binienda ZK,Ross IA,Gough B,Riccio T,Kim CS,Ali SF

更新日期：2010-01-29 00:00:00

abstract：:Contact heat evoked potentials (CHEPs) have been difficult to elicit due to slow temperature rise times. A recently developed heat-foil technology was used to elicit pain and CHEPs. Two groups of subjects were separately stimulated at the left arm with contact heat via one fast-acting (70 degrees C/s) heat-foil thermo...

journal_title：Neuroscience letters

authors： Chen AC,Niddam DM,Arendt-Nielsen L

更新日期：2001-12-01 00:00:00

abstract：:Acrolein-induced oxidative stress is hypothesized to involve in the etiology of Alzheimer's disease (AD). Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) have antioxidative and neuroprotective properties. The present study investigated the protective effects of CA/CAPE on acrolein-induced oxidative neuronal ...

journal_title：Neuroscience letters

authors： Huang Y,Jin M,Pi R,Zhang J,Chen M,Ouyang Y,Liu A,Chao X,Liu P,Liu J,Ramassamy C,Qin J

更新日期：2013-02-22 00:00:00

abstract：:Intracellular cyclic AMP regulation systems play an important role in the mechanisms of morphine dependence and withdrawal. In the present study, to clarify the involvement of phosphodiesterase (PDE) 4, degradation enzyme of cyclic AMP in morphine dependence and withdrawal we investigated the activities of PDE4 after ...

journal_title：Neuroscience letters

authors： Kimura M,Tokumura M,Itoh T,Inoue O,Abe K

更新日期：2006-08-14 00:00:00

abstract：:Employing video-enhanced contrast (VEC) microscopy, we examined whether TAK-029 (GPIIb/IIIa antagonist) inhibits the adhesion of activated platelets to human brain microvascular endothelial cells (HBEC) in vitro. HBECs were cultured on a coverglass and put in the observation chamber of VEC microscopy. Then, activated ...

journal_title：Neuroscience letters

authors： Tanahashi N,Fukuuchi Y,Tomita M,Tomita Y,Inoue K,Satoh H,Abe T

更新日期：2001-03-23 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Akathisia is characterized by restlessness and crawling sensations similar to restless legs syndrome (RLS). Long latency flexor reflex (LLFR) which has helped to advance RLS pathophysiology has never been investigated in akathisia. Due to the clinical commonalities of akathisia and RLS, we inve...

journal_title：Neuroscience letters

authors： Gunduz A,Metin B,Metin SZ,Poyraz BC,Karadeniz D,Kiziltan G,Kiziltan ME

更新日期：2017-02-22 00:00:00

abstract：:Emerging evidence suggests that the SNP rs2736990 of SNCA is a susceptibility factor for idiopathic Parkinson's disease (PD) in different populations, but the studies which examined the association have provided inconsistent results. Therefore, we performed a meta-analysis of some case-control studies to obtain a more...

journal_title：Neuroscience letters

authors： Fang J,Hou B,Liu H,Zhang X,Wang J,Zhou C,Xie A

更新日期：2017-09-29 00:00:00

abstract：:In untreated patients with Parkinson's disease (PD), the total (free and conjugated) serotonin (5-HT) and dopamine (DA) concentrations in the cerebrospinal fluid decreased significantly. While the 5-HT concentration displayed a non-significant trend of negative correlation with the DA concentration in controls, it had...

journal_title：Neuroscience letters

authors： Tohgi H,Abe T,Takahashi S,Takahashi J,Hamato H

更新日期：1993-09-03 00:00:00

abstract：:Twenty-four hour patterns in somatostatin (SS)-like immunoreactivity (LI) within the suprachiasmatic nucleus (SCN) were determined by enzyme immunoassay in rats blinded by bilateral orbital enucleation or kept sighted under light-dark conditions. A remarkable circadian rhythm was found in the concentration of SS-LI in...

journal_title：Neuroscience letters

authors： Shinohara K,Isobe Y,Takeuchi J,Inouye ST

更新日期：1991-08-05 00:00:00

abstract：:Online shopping festivals play a significant role in consumers' purchase decision and have been the focus of much research and many marketing practices. However, research has yet to explore which product categories can promote consumer purchase intention during online shopping festivals. This study carried out a neuro...

journal_title：Neuroscience letters

authors： Shang Q,Jin J,Qiu J

更新日期：2020-01-10 00:00:00

abstract：:The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, s...

journal_title：Neuroscience letters

authors： Evans HF,Huntley GW,Morrison JH,Shine J,Paxinos G

更新日期：1992-11-09 00:00:00

abstract：:Mouse neuroblastoma x rat glioma hybrid cells (N x G, NG108-15) were used to study the mechanism of Ca(2+)-current (ICa) inhibition by 5-hydroxytryptamine (5-HT). 5-HT caused a dose-dependent decrease of ICa which was abolished by ICS 205-930 (10)(-8) M) while 2-methyl-5-HT was an agonist. Intracellular infusion of GD...

journal_title：Neuroscience letters

authors： Eckert R,Utz J,Trautwein W

更新日期：1993-04-16 00:00:00

abstract：:To clarify the psychopharmacological profile of blonanserin, a novel antipsychotic, we examined its effect on the methamphetamine-induced disruption of latent inhibition (LI) and the neural activation related to this effect in rats. To evaluate the LI, we used a conditioned emotional response in which a tone (conditio...

journal_title：Neuroscience letters

authors： Kuramashi A,Abe H,Koganemaru G,Matsuo H,Ikeda T,Ebihara K,Funahashi H,Takeda R,Nishimori T,Ishida Y

更新日期：2013-08-09 00:00:00

abstract：:Histone modifications, such as lysine methylation, acetylation and ubiquitination, are epigenetic tags that shape the chromatin landscape and regulate transcription required for synaptic plasticity and memory. Here, we show that transcription-promoting histone H3 trimethylated at lysine 4 (H3K4me3), histone H3 acetyla...

journal_title：Neuroscience letters

authors： Bach SV,Tacon PR,Morgan JW,Hegde AN

更新日期：2015-03-30 00:00:00

abstract：:The localization of cells which produce estrogen receptors in the rat central nervous system was performed using an in situ hybridization technique. For this, we used a synthetic oligonucleotide probe labeled with 35S complementary to the mRNA coding for a fragment (1-24) of estradiol receptor which is not common to t...

journal_title：Neuroscience letters

authors： Pelletier G,Liao N,Follea N,Govindan MV

更新日期：1988-11-22 00:00:00