Extrapyramidal symptoms in Frontotemporal Dementia: prevalence and clinical correlations.

abstract：:The autonomic nervous system is importantly involved in the maintenance of arterial pressure during orthostatic challenges. However, little is known about the specific central areas involved in these cardiovascular compensations. It has been proposed that the paraventricular nucleus of the hypothalamus (PVN) is involv...

journal_title：Neuroscience letters

authors： de Andrade O,Borghi SM,de Souza HC,Fontes MA,Martins-Pinge MC

更新日期：2014-01-13 00:00:00

abstract：:The level of endogenous nerve growth factor (NGF) in rat sciatic nerve was determined using a highly sensitive two-site enzyme immunoassay. After crushing this nerve NGF accumulated linearly distal to the crush during the first 12 h to reach levels 13-fold higher than in the uncrushed contralateral side. In contrast, ...

journal_title：Neuroscience letters

authors： Korsching S,Thoenen H

更新日期：1983-08-19 00:00:00

abstract：:Sciatic axotomy in 2-day-old rats (P2) causes lumbar motoneuron loss, which could be associated with nitric oxide (NO) production. NO may be produced by three isoforms of synthase (NOS): neuronal (nNOS), endothelial (eNOS) and inducible (iNOS). We investigated NOS expression and NO synthesis in the lumbar enlargement ...

journal_title：Neuroscience letters

authors： Rogério F,Teixeira SA,Júnior HJ,Maria CC,Vieira AS,de Rezende AC,Pereira GA,Muscará MN,Langone F

更新日期：2006-10-23 00:00:00

abstract：:The activity of single units in the striatum of urethane-anesthetized rats was recorded before and after the systemic administration of 7-nitro-indazole (7-NI; 50 mg/kg intraperitoneally), a selective inhibitor of neuronal nitric oxide (NO) synthase. Two neuronal types were clearly distinguishable electrophysiological...

journal_title：Neuroscience letters

authors： Sardo P,Ferraro G,Di Giovanni G,Galati S,La Grutta V

更新日期：2002-06-14 00:00:00

abstract：:To elucidate the mechanisms of individual differences in pain and analgesic sensitivity, we analyzed the variable number of tandem repeat polymorphism in the third exon of the dopamine D4 receptor gene. Alleles that were less than four repeats long and four or more repeats long were considered Short and Long, respecti...

journal_title：Neuroscience letters

authors： Aoki Y,Nishizawa D,Kasai S,Fukuda K,Ichinohe T,Yamashita S,Ikeda K

更新日期：2013-05-10 00:00:00

abstract：:In human caudate and cortex membranes, [3H]serotonin ([3H]5-HT) labels 5-HT1A and 5-HT1C recognition sites which show nanomolar affinity for 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin) and mesulergine respectively, whereas no 5-HT1B binding could be identified. However, the majority of the sites labelled by [3...

journal_title：Neuroscience letters

authors： Hoyer D,Waeber C,Pazos A,Probst A,Palacios JM

更新日期：1988-03-10 00:00:00

abstract：:Xenopus oocytes were injected with mRNA from adult or neonatal rat spinal cord, or from adult cerebral cortex, and examined electrophysiologically to measure currents elicited by various receptor agonists. The mRNAs induced the oocytes to acquire similar types of amino acid receptors, albeit with different potencies. ...

journal_title：Neuroscience letters

authors： Akagi H,Miledi R

更新日期：1988-12-19 00:00:00

abstract：:The effects of treadmill exercise training on prepro-galanin (GAL) and tyrosine hydroxylase (TH) gene expression in the locus coeruleus (LC) were examined. Male Fischer-344 rats (n=9) were assigned to 6 weeks of treadmill running. An additional group of animals comprised the sedentary home cage control group (n=9). Le...

journal_title：Neuroscience letters

authors： O'Neal HA,Van Hoomissen JD,Holmes PV,Dishman RK

更新日期：2001-02-16 00:00:00

abstract：:We investigated changes in the corticospinal pattern of activity in healthy volunteers during sustained noxious and non-noxious mechanical stimulation of the first hand digit, resulting from active (self-stimulation) or passive (externally-induced) pressing against a sharp or blunted tip. The results indicate that, in...

journal_title：Neuroscience letters

authors： Fadiga L,Craighero L,Dri G,Facchin P,Destro MF,Porro CA

更新日期：2004-05-06 00:00:00

abstract：:The structure of CACNA1G, the gene encoding alpha1G, a human brain T Ca2+ channel alpha1 subunit, was determined by comparison of polymerase chain reaction-amplified brain cDNA and genomic sequences. The gene consists of at least 38 exons, two of them newly-identified, spanning at least 66490 basepairs of chromosome 1...

journal_title：Neuroscience letters

authors： Mittman S,Guo J,Agnew WS

更新日期：1999-10-29 00:00:00

abstract：:NCB-20 cells expressed m1- and m4-muscarinic acetylcholine receptor (mAChR) mRNAs, while NG108-15 cells expressed only m4-mAChR mRNA. Butyrate induced a time-dependent increase in the level of m1-mAChR mRNA with no change in the m4-mAChR mRNA level in NCB-20 cells. Similarly, butyrate did not affect the m4-mAChR mRNA ...

journal_title：Neuroscience letters

authors： Fukamauchi F,Mataga N,Wang YJ,Chuang DM

更新日期：1996-07-05 00:00:00

abstract：:An increase in diaphragmatic electromyogram (EMG) recorded via oesophageal electrodes during positive pressure breathing has been reported to indicate an increase in the neural outflow to the muscle. However, using similar techniques, the size of compound muscle action potentials produced by supramaximal phrenic nerve...

journal_title：Neuroscience letters

authors： McKenzie DK,Gandevia SC

更新日期：1986-09-25 00:00:00

abstract：:Peripheral nerve transection results in a disconnection of the neuron from its target. As a result, a series of metabolic changes occur in the cell body that may cause neuronal death, mainly by apoptotic mechanisms. Although neurons from neonatal animals are the most susceptible, peripheral, lesion-induced, neuronal l...

journal_title：Neuroscience letters

authors： Pierucci A,de Oliveira AL

更新日期：2006-03-27 00:00:00

abstract：:We investigated the anti-hyperalgesic effect of FR140423, 3-(difluoromethyl)-1-(4-methoxyphenyl-5-[4-(methylsulfinyl)phenyl]pyrazole, in a rat model of postoperative pain. Oral administration of FR140423 at doses between 1 and 100 mg/kg after surgery dose dependently attenuated the punctate mechanical hyperalgesia cau...

journal_title：Neuroscience letters

authors： Ochi T,Ohkubo Y,Mutoh S

更新日期：2003-10-16 00:00:00

abstract：:Although the therapeutic use of microglia has received some attention for the treatment of brain diseases, few non-invasive techniques exist for monitoring the cells after administration. Here, we present a technique using magnetic resonance imaging (MRI) to track microglia injected intra-cardially. We labeled microgl...

journal_title：Neuroscience letters

authors： Song Y,Morikawa S,Morita M,Inubushi T,Takada T,Torii R,Tooyama I

更新日期：2006-02-27 00:00:00

abstract：:The norepinephrine (NE) and dopamine (DA) content of the cat carotid body (CB) in vivo was investigated under normoxic and hypoxic conditions (5% O2 for 1 h) by radiolabelling method. To avoid a large scattering of the measured values due to inhomogeneity of the biological material, young sib animals were used. The me...

journal_title：Neuroscience letters

authors： Starlinger H,Acker H

更新日期：1986-02-14 00:00:00

abstract：:In anaesthetised cats, antibody microprobes were used to measure the release of immunoreactive calcitonin gene-related peptide (irCGRP) in the lumbar dorsal horn during stimulation of non-nociceptive or nociceptive primary afferent fibres. Release of irCGRP was detected in the substantia gelatinosa, where immunostaini...

journal_title：Neuroscience letters

authors： Morton CR,Hutchison WD

更新日期：1990-09-18 00:00:00

abstract：:Immediate post-training intraperitoneal administration of the centrally acting anticholinesterase physostigmine (70.0, or 150.0 microg/kg) enhanced retention of male CF-1 mice tested 48 h after training in a one-trial step-through inhibitory avoidance task (0.8 mA, 50 Hz, 1 s footshock). The effect was observed in mic...

journal_title：Neuroscience letters

authors： Boccia MM,Blake MG,Acosta GB,Baratti CM

更新日期：2003-07-17 00:00:00

abstract：:In the present study we investigated the effect of electrolytic lesion of the medial septal area (MSA) on the dipsogenic, natriuretic, kaliuretic and pressor responses elicited by intracerebroventricular (i.c.v.) injection of the cholinergic agonist carbachol. Freely moving rats with sham or MSA lesion (1-7 days and 1...

journal_title：Neuroscience letters

authors： Luiz AC,Saad WA,Camargo LA,Renzi A,De Luca Junior LA,Menani JV

更新日期：1991-11-11 00:00:00

abstract：:Protein profiling of cerebrospinal fluid in Guillain-Barrè syndrome (GBS), an acute and immune-mediated disease affecting the peripheral nervous system, was performed by two-dimensional electrophoresis. Significant modulated spots in GBS patients vs. control groups (a group of multiple sclerosis patients and one of he...

journal_title：Neuroscience letters

authors： D'Aguanno S,Franciotta D,Lupisella S,Barassi A,Pieragostino D,Lugaresi A,Centonze D,D'Eril GM,Bernardini S,Federici G,Urbani A

更新日期：2010-11-12 00:00:00

abstract：:GABAergic modulation of enkephalin, substance P and glutamic acid decarboxylase (GAD67) gene expression and the alterations induced by dopamine receptor blockade were studied in the rat striatum. Following subchronic treatment with the GABA-A agonist muscimol, the GABA-B agonist baclofen or the GABA transaminase inhib...

journal_title：Neuroscience letters

authors： Jolkkonen J,Jenner P,Marsden CD

更新日期：1994-10-24 00:00:00

abstract：:A new non-N-methyl-D-aspartate (non-NMDA) glutamate receptor antagonist, GYKI 52466, was tested on L-glutamate (Glu)-, kainate (KAI)- and NMDA-induced responses in vivo, using both extracellular recording of antidromic field potentials and intracellular recording from rat abducens motoneurones. Intravenous (5-10 mg/kg...

journal_title：Neuroscience letters

authors： Ouardouz M,Durand J

更新日期：1991-04-15 00:00:00

abstract：:Growth associated protein-43 (GAP-43) gene induction may be involved in reactive events that follow cerebral ischemic damage. Antagonists of the N-methyl-D-aspartate (NMDA) subclass of glutamate receptors are thought to ameliorate functional outcome after ischemic injury. To assess whether glutamate NMDA receptor bloc...

journal_title：Neuroscience letters

authors： Luque JM,Puig N,Martínez JM,González-García C,Ceña V

更新日期：2001-06-08 00:00:00

abstract：:Supporting cell mitosis contributes significantly to hair cell regeneration in the acoustically damaged bird inner ear. Yet there may be another mechanism of hair cell replacement: supporting cell conversion. This study used cytosine arabinoside (Ara-C), an inhibitor of DNA synthesis, to better determine whether suppo...

journal_title：Neuroscience letters

authors： Adler HJ,Raphael Y

更新日期：1996-02-16 00:00:00

abstract：:The influence of testosterone on the postnatal development of reflex electromyographic (EMG) jaw muscle activity evoked by injection of mustard oil (MO) into the temporomandibular joint region and the later recurrence of this EMG activity after intravenous injection of naloxone, was studied in male rats. MO-evoked EMG...

journal_title：Neuroscience letters

authors： Seo K,Fujiwara N,Cairns BE,Someya G

更新日期：2002-12-25 00:00:00

abstract：:Substance P (SP) immunocytochemistry and receptor autoradiography were used to define the innervation of the equine synovial membrane of joints equivalent to the wrist and knuckle of man. SP-immunoreactive fibers were mainly concentrated around blood vessels in the subsynovial layer, although not exclusively, while in...

journal_title：Neuroscience letters

authors： Bowker RM,Sonea IM,Vex KB,Caron JP

更新日期：1993-12-24 00:00:00

abstract：:The effect of different frequencies of music on brain function was investigated through measurement of blood pressure in spontaneously hypertensive rats (SHR). Previous studies indicated that exposure to Mozart's music (K. 205) leads to increased calcium/calmodulin-dependent dopamine synthesis in the brain, and that t...

journal_title：Neuroscience letters

authors： Akiyama K,Sutoo D

更新日期：2011-01-03 00:00:00

abstract：:In the superoxide dismutase 1 (SOD1)(G93A G1H) transgenic mouse, the primary pathology and disease signs are associated with the degeneration of motor neurons in the lumbar spinal cord. It is unclear if the descending motor pathways from the cortex and brainstem are also compromised. The retrograde tracer Fluorogold w...

journal_title：Neuroscience letters

authors： Zang DW,Cheema SS

更新日期：2002-10-31 00:00:00

abstract：:Samples collected from rabbit neocortical surface during a tetanic stimulation of the neocortex induced neurite growth in PC-12 cells in culture and synaptic long-term potentiation (LTP) in guinea pig hippocampal slices. If these samples were preheated and cooled, or if they were collected in the absence of a tetanic ...

journal_title：Neuroscience letters

authors： Sastry BR,Chirwa SS,May PB,Maretić H

更新日期：1988-08-15 00:00:00

abstract：:The purpose of the study was to investigate the accuracy of location of equivalent current dipoles estimated by the dipole tracing method (DT) utilizing a realistic 3-shell (scalp-skull-brain) head model (SSB-DT). Three patients with intractable complex partial seizures, diagnosed as having typical temporal seizures w...

journal_title：Neuroscience letters

authors： Homma I,Masaoka Y,Hirasawa K,Yamane F,Hori T,Okamoto Y

更新日期：2001-05-18 00:00:00