Adhesion of adenosine diphosphate-activated platelets to human brain microvascular endothelial cells under flow in vitro is mediated via GPIIb/IIIa.

abstract：:A novel preparation for the study of male and female sexual function in anesthetized, acutely spinalized rats is reported. In both sexes, the coitus reflex (the neuromuscular concomitants of sexual climax) could be elicited by mechanical stimulation of the distal urethra. It is concluded that the spinal sexual circuit...

journal_title：Neuroscience letters

authors： Chung SK,McVary KT,McKenna KE

更新日期：1988-12-05 00:00:00

abstract：:Strengthening of synaptic connections has been proposed to underlie information storage in the brain, and experience-dependent increases in synapse number have been observed. However, the effect of these new synapses on the specific connectivity, and thus function, of a given brain area remains largely unknown. We rep...

journal_title：Neuroscience letters

authors： Federmeier KD,Kleim JA,Greenough WT

更新日期：2002-11-08 00:00:00

abstract：:Mitogen-activated protein kinases (MAPK) can be activated by opioids such as morphine via opioid receptor, and their activations have been observed in synaptic plasticity, learning, memory and addiction. Long-term exposure to morphine may induce physical dependence, manifested as somatic withdrawal symptoms such as di...

journal_title：Neuroscience letters

authors： Li T,Hou Y,Cao W,Yan CX,Chen T,Li SB

更新日期：2010-01-14 00:00:00

abstract：:Thioredoxin (TRX) is a small, multifunctional protein with a redox-active site and multiple biological functions that include reducing activity for reactive oxygen intermediates. We assayed TRX by immunohistochemical methods in the rat brain after intraperitoneal injection of 3-nitropropionic acid (3-NP), an irreversi...

journal_title：Neuroscience letters

authors： Sugino T,Nozaki K,Takagi Y,Hattori I,Hashimoto N,Yodoi J

更新日期：1999-11-12 00:00:00

abstract：:Lucifer Yellow (LY) selectively labels embryonic chick amacrine cells from days 11 until 14 in vivo. Its usefulness as an in vitro marker was investigated. In vivo labeling and subsequent culturing was not possible due to dye leakage. Neurons, however, could be labeled at various times in vitro. The number of neurons ...

journal_title：Neuroscience letters

authors： Zeevalk GD,Hyndman AG

更新日期：1986-03-14 00:00:00

abstract：:The mammalian circadian system contains both central and peripheral oscillators. It was reported that the rhythmic expressions of period homolog 2 (per2) mRNA in peripheral tissues were abolished by the suprachiasmatic nucleus (SCN) lesions. However, there are no reports that ventromedial hypothalamic (VMH) lesions ca...

journal_title：Neuroscience letters

authors： Kiba T,Kintaka Y,Suzuki Y,Ishizuka N,Ishigaki Y,Inoue S

更新日期：2010-03-08 00:00:00

abstract：:The intramedullary axon collateral systems of adult cat spinal alpha-motoneurones were studied with morphological and physiological techniques 12 weeks after peripheral transection of the motor axons. Morphologically, intracellular horseradish peroxidase (HRP) staining showed that the axotomy induced an elimination of...

journal_title：Neuroscience letters

authors： Havton L,Kellerth JO

更新日期：1984-11-23 00:00:00

abstract：:In this study, the effects of 5-HT4 receptors of the CA1 on MK801-induced amnesia and hyperlocomotion were examined. One-trial step-down method was used to assess memory retention and then, the hole-board method to assess exploratory behaviors. The results showed that post-training intra-CA1 administration of RS67333 ...

journal_title：Neuroscience letters

authors： Nasehi M,Tabatabaie M,Khakpai F,Zarrindast MR

更新日期：2015-02-05 00:00:00

abstract：:The effect of calcium on the biogenic amine level and distribution in the mouse brain was investigated by a histochemical method using a microscopic photometer (Pl, Nikon). Histochemical fluorescence intensities in the corpus striatum and cortex cerebri regions were significantly increased by the intraventricular admi...

journal_title：Neuroscience letters

authors： Sutoo D,Akiyama K

更新日期：1986-08-15 00:00:00

abstract：:The purpose of the present study was to confirm the functional regulation by alpha 2-adrenoceptors of the release of serotonin (5-HT) from the rat hippocampus in vivo. Under several pharmacological conditions, extracellular levels of 5-HT were estimated by assaying its concentrations in the perfusate by high performan...

journal_title：Neuroscience letters

authors： Numazawa R,Yoshioka M,Matsumoto M,Togashi H,Kemmotsu O,Saito H

更新日期：1995-06-16 00:00:00

abstract：:Many experimental observations have demonstrated the modulatory role exerted by several neural structures and neurotransmitters on spontaneous and paroxysmal bioelectric activity of the hippocampus. Recently, the control exerted by locus coeruleus (LC) and its noradrenergic (NA) efferent pathway on different experimen...

journal_title：Neuroscience letters

authors： Ferraro G,Sardo P,Sabatino M,Caravaglios G,La Grutta V

更新日期：1994-03-14 00:00:00

abstract：:Functional neuroimaging suggests asymmetries of memory encoding and retrieval in the prefrontal lobes, but different hypotheses have been presented concerning the nature of prefrontal hemispheric specialization. We studied an associative memory task involving pairs of Kanji (Chinese) pictographs and unfamiliar abstrac...

journal_title：Neuroscience letters

authors： Epstein CM,Sekino M,Yamaguchi K,Kamiya S,Ueno S

更新日期：2002-03-01 00:00:00

abstract：:In newborns, hypoxia elicits defensive behaviors including awakening from sleep, body movements and crying. An inability to produce this defense response is a risk factor for sudden infant death syndrome and other respiratory control disorders. In this study, we examined the possibility that the defense response to hy...

journal_title：Neuroscience letters

authors： Bollen B,Bouslama M,Matrot B,D'Hooge R,Van den Bergh O,Gallego J

更新日期：2007-06-15 00:00:00

abstract：:The ability of three nitric oxide (NO) donor compounds to modify ligand binding to kainate receptors was studied in tissue from human adult autopsy brains. Binding of [3H]kainic acid (5 nM) was measured in frontal cortex membranes made from Brodmann area 8 (BA 8) and autoradiographically using sections of frontal cort...

journal_title：Neuroscience letters

authors： Lees RD,Slater P,D'Souza SW

更新日期：1997-09-19 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is a promising method for use in the clinical field, as it can induce modulation of cortical excitability. Generally, rTMS inhibits the motor cortex when delivered at less than 1 Hz. However, it has been indicated that a facilitative effect is induced by 1 Hz rTMS, d...

journal_title：Neuroscience letters

authors： Nojima K,Iramina K

更新日期：2018-01-18 00:00:00

abstract：:1-methyl-4-phenylpyridinium ion (MPP(+)) has been shown to selectively inhibit mitochondrial function and induce a parkinsonism-like syndrome. MPP(+) stimulates the production of reactive oxygen species (ROS) and induces cell death in vitro. In this study, we investigated the protective effects of okadaic acid on MPP(...

journal_title：Neuroscience letters

authors： Ahn KH,Kim YS,Kim SY,Huh Y,Park C,Jeong JW

更新日期：2009-01-09 00:00:00

abstract：:Effects of intracerebroventricular (i.c.v.) administration of atrial natriuretic polypeptide (ANP) on renal sympathetic nerve activity (RSNA) and renal blood flow (RBF) were examined in conscious rats. Administration of ANP had no appreciable effects on baseline RSNA and RBF. The pressor response induced by i.c.v. ang...

journal_title：Neuroscience letters

authors： Kannan H,Ueta Y,Nakamura T,Yamashita H,Hayashida Y

更新日期：1990-08-14 00:00:00

abstract：:Suicide is a major contributor to the morbidity and mortality of schizophrenia, accounting for approximately 10% of deaths in these patients. Genetic factors have been reported to modulate the risk for suicide, although the precise mechanism and magnitude of the genetic contribution are unknown. Further, suicide attem...

journal_title：Neuroscience letters

authors： Souza RP,De Luca V,Manchia M,Kennedy JL

更新日期：2011-02-11 00:00:00

abstract：:MicroRNA-146a (miRNA-146a) is an inducible, 22 nucleotide, small RNA over-expressed in Alzheimer's disease (AD) brain. Up-regulated miRNA-146a targets several inflammation-related and membrane-associated messenger RNAs (mRNAs), including those encoding complement factor-H (CFH) and the interleukin-1 receptor associate...

journal_title：Neuroscience letters

authors： Li YY,Cui JG,Dua P,Pogue AI,Bhattacharjee S,Lukiw WJ

更新日期：2011-07-20 00:00:00

abstract：:Although the relationship between hyperglycemia (using diabetic animal model) and plasma nitrotyrosine level has been studied, the effect of hypoglycemia on nitrotyrosine level in the brain has not been addressed. Here, we evaluated nitration of protein, the colocalization of nitration with alpha-synuclein, activity o...

journal_title：Neuroscience letters

authors： Liu Y,He R

更新日期：2010-03-26 00:00:00

abstract：:Mood stabilizers are a category of medications used in the management of mood disorders. The mood stabilizing properties of lithium were first reported in 1949 by John Cade, and since then it has been considered the first line treatment for bipolar disorder. Despite presenting more differences than similarities, mood ...

journal_title：Neuroscience letters

authors： Pisanu C,Papadima EM,Del Zompo M,Squassina A

更新日期：2018-03-16 00:00:00

abstract：:Rats with suprachiasmatic nuclei (SCN) lesions did not show increased sleep after triazolam (TRZ) injections at any dose from 0.2 to 1.6 mg/kg, whereas 0.4 mg/kg TRZ given intact rats in the middle of their activity phase significantly increased sleep. Across SCN-lesioned and intact rats, the amount of sleep before an...

journal_title：Neuroscience letters

authors： Edgar DM,Seidel WF,Martin CE,Sayeski PP,Dement WC

更新日期：1991-04-29 00:00:00

abstract：:The DNA-binding activity of nuclear factor (NF-kB) was found to be induced in the spinal cord of rats with experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), from the onset of the disease. This activation of NF-kB persisted throughout the disease period and decreased thereafter ...

journal_title：Neuroscience letters

authors： Pahan K,Schmid M

更新日期：2000-06-16 00:00:00

abstract：:A strong link between obesity and dopamine (DA) has been established by studies associating body weight status to variants of genes related to DA signalling. Human and animal studies investigating this relationship have so far focused mainly on the role of DA within the mesolimbic pathway. The aim of this study was to...

journal_title：Neuroscience letters

authors： Alsiö J,Rask-Andersen M,Chavan RA,Olszewski PK,Levine AS,Fredriksson R,Schiöth HB

更新日期：2014-01-24 00:00:00

abstract：:Parkinson's disease (PD) is one of the common neurodegenerative diseases that result in the progressive damage of dopaminergic neurons. Environmental exposure, including paraquat, is considered risky for PD. Epigenetics refer to the study of heritable changes in gene expression that occur without a change in DNA seque...

journal_title：Neuroscience letters

authors： Kong M,Ba M,Liang H,Ma L,Yu Q,Yu T,Wang Y

更新日期：2012-08-22 00:00:00

abstract：:The putative anti-addiction alkaloid ibogaine and its principal metabolite 12-hydroxyibogamine appear to act at the (+)-5 methyl-10,11,dihydro-5H- dibenzo[a,d]cycloheten-5-10-imine maleate (MK-801) binding site in the N-methyl-D-aspartate (NMDA)-receptor cation channel. This conclusion is based on findings that both c...

journal_title：Neuroscience letters

authors： Mash DC,Staley JK,Pablo JP,Holohean AM,Hackman JC,Davidoff RA

更新日期：1995-06-02 00:00:00

abstract：:Extracellular noradrenaline was measured on-line in the cerebral cortex of the freely moving rat by microdialysis coupled to high performance liquid chromatography and electrochemical detection. High potassium concentrations in the perfusion fluid led to a strong increase, whereas tetrodotoxin led to almost undetectab...

journal_title：Neuroscience letters

authors： van Veldhuizen MJ,Feenstra MG,Boer GJ,Westerink BH

更新日期：1990-11-13 00:00:00

abstract：:The purpose of this investigation was to evaluate the effect and mechanisms of electroacupuncture (EA) at the bilateral Zusanli acupoints (ST-36) on glucose tolerance in normal rats. Intravenous glucose tolerance test (IVGTT) was performed to examine the effects of electroacupuncture (EA) on glucose tolerance in rats....

journal_title：Neuroscience letters

authors： Lin RT,Chen CY,Tzeng CY,Lee YC,Cheng YW,Chen YI,Ho WJ,Cheng JT,Lin JG,Chang SL

更新日期：2011-04-25 00:00:00

abstract：:It has been reported that tyrosine administration augments clozapine-induced dopamine (DA) release in the medial prefrontal cortex (MPFC). To characterize this effect and exclude possible confounds, we conducted a series of studies in which microdialysate collection started 24 h after probe implantation, a time at whi...

journal_title：Neuroscience letters

authors： Jaskiw GE,Simpson C,Bongiovanni R,Yamamoto BK

更新日期：2004-02-26 00:00:00

abstract：:We describe the incidence of gamma-aminobutyric acid (GABA)ergic neurons after post-embedding immunocytochemistry on semithin sections of the claustrum, putamen and lateral, dorsal and medial cortical areas. Twelve percent of the neurons counted in the claustrum of 11 rabbits were GABAergic. This incidence was signifi...

journal_title：Neuroscience letters

authors： Gómez-Urquijo SM,Gutiérrez-Ibarluzea I,Bueno-López JL,Reblet C

更新日期：2000-03-24 00:00:00